Pathogenicity ndi virulence tizilombo. Virulence - izo ...

Thupi pafupifupi 100 trillionov mabakiteriya. Asayansi a lero ndi chabe tsopano bwino momwe izi madera zovuta kucheza ndi munthu. Iwo bwanji ndondomeko ya chimbudzi, chitetezo cha m'thupi mwinanso pa maganizo bwino. Komabe, si mabakiteriya onse akhoza azikhala limodzi ndi thupi mwamtendere. Likutchedwa tizilombo bakiteriya zimene zingachititse matenda zomera, nyama kapena tizilombo. Tizilombo posonyeza pathogenicity pogwiritsa virulence. Choncho, kodi virulence?

Lingaliro la virulence

Virulence - ndi mawu pofotokoza mlingo wa pathogenicity wa tizilombo toyambitsa matenda a. Choncho, determinants wa virulence wa tizilomboto ndi aliyense wa, zochititsa majini amuzolengedwa kapena structural kuti amalola matenda chifukwa.

Kubverana khamu ndi tizilomboto nthawi zonse zazikulu, chifukwa aliyense akhoza kusintha ntchito ndi ntchito za ena. Zotsatira za ubale zimadalira virulence wa tizilomboto ndi digiri wachibale kukana kapena chiwopsezo cha nkhondo. Yofunika kwambiri amadziwikanso ankaimba mogwira wa asilikali oteteza wa chamoyo.

zinthu Virulence mwachindunji zokhudzana ndi katundu amene amalola tizilombo zoipa kulowa mkati kapena pa thupi la khamu ndi chifukwa matenda. Izi poizoni bakiteriya zimene zimachititsa pathogenicity lapansi.

mfundo zofunika

Invasiveness - ichi nzeru mu minofu. Pamafunikanso njira kwa kulamulira zotheka ndi kupanga zinthu extracellular zimene zimachititsa kuti n'zotheka kuwukira ndi circumvent kapena kusiya njira zina zodzitetezera.

Toksogennost - kukhoza excrete poizoni. Mabakiteriya zingabweretse mitundu iwiri ya poizoni: endotoxins ndi exotoxins. Exotoxins kumasulidwa ku maselo bakiteriya ndi kulimbikitsa kukula kwa mabakiteriya. Endotoxins ndi selo mankhwala.

poizoni bakiteriya, onse sungunuka ndi selo kugwirizana, akhoza kusamutsidwa ndi mwazi ndi lymph minofu ndi kuyambitsa zotsatira cytotoxic m'madera akumidzi ku mfundo koyamba malowedwe. Ena bakiteriya poizoni mukhoza kutsegula madera nawo kuwukira lapansi.

Pathogenicity ndi virulence tizilombo

Pathogenicity - luso la chamoyo matenda. Luso limeneli ndi chibadwa zikuluzikulu za tizilomboto, amene amawononga mbali makamu. Kwa tizilombo toyambitsa matenda osiyanasiyana, luso limeneli matenda si titadziwa. Tizilombo toyambitsa matenda akhoza kufotokoza osiyanasiyana virulence.

Virulence - mfundo imene inextricably zogwirizana ndi mfundo pathogenicity. Mlingo wa virulence wa tizilomboto pa nthawi chilamulira chikhalidwe ndi luso motsanzira mu khamu ndi amadalira zinthu zina. virulence zinthu ziti zimene zingathandize kuti pathogenicity ndi, mwachitsanzo kuthandiza matenda.

tizilomboti

Ambiri ikufotokoza mobwerezabwereza kuti zolengeza zosiyanasiyana za malonda mankhwala amati kupha 99% ya majeremusi. Tizilomboto - ndi anawagwiritsa ntchito pofotokoza zinthu zazing'ono (mabakiteriya ndi tizilombo tina), kuchititsa matenda osiyanasiyana. Mu terminology zamoyo, imatchedwanso monga nthumwi causative. Pali mitundu ingapo ya toyambitsa matenda osiyanasiyana chifukwa kuyambira chimfine ndi kutha khansa.

tizilombo toyambitsa matenda kusokoneza munthu m'njira zosiyanasiyana, malingana virulence awo. Virulence - ndi anawagwiritsa ntchito pofotokoza mphamvu ya tizilomboto makamaka. Tizilomboto mosamva ali, m'pamenenso adzakhala kungasokoneze thanzi la munthu.

Zinthu za virulence

Virulence zinthu M'magazini toyambitsa kudziwa nazo tizilomboto virulence. The kwambiri, wamkulu mosavuta kuti adzakhala chifukwa cha matenda. zinthu izi mwayi polimbana ndi dongosolo anthu m'thupi, ndi zambiri, m'pamenenso iwo kungawononge.

Pali mitundu yosiyanasiyana ya zinthu virulence kuti akhale kwathu kapena kwina pa tizilomboto makamaka: zinthu za kulamulira, enterotoxins ndi hemolysin. Virulence - n'kofunika kachulukidwe, kuimira digiri ya matenda chifukwa cha bakiteriya a. Mbali imeneyi, limene zimachitika pakati pa tizilomboto ndipo chotengera. Virulence nthawi chilamulira chikhalidwe ndi luso tizilomboto kuti zikupitiriza. Ichinso amadalira chonyamulira ndi zinthu zachilengedwe.

A tizilomboto bakiteriya kawirikawiri chimatanthauza bakiteriya aliyense amatha kuchititsa matenda. umatha kupangitsa matenda amatchedwa tizilombo toyambitsa matenda. The virulence wa bakiteriya ndi mwachindunji amadalira chikhalidwe cha matenda ndipo ndi chizindikiro cha kukula kwa matenda zimabweretsa.