Mankhwala jini

Gene mankhwala - mankhwala ndi cholowa sanali cholowa, matenda multifactorial, yomwe ikuchitika mwa kuyambitsa jini mu mtima maselo ena. Cholinga cha mankhwala ndi kuthetsa nthenda ya kumtundu kapena kupereka maselo a zatsopano. zosavuta kulowa mu khungu ndi wathanzi, kwathunthu ntchito jini, kusiyana ndi kungokonza zopindika alipo.

Gene mankhwala okha kuti maphunziro zimakhala somatic. Ichi ndi chifukwa chakuti kusokonezedwa aliyense ndi maselo kugonana ndi embryonic angapereke zotsatira sizimadziwika kwambiri.

Panopa njira Akutsatira othandiza kuchiza matenda onse monogenic ndi multifactorial (zotupa zilonda, mitundu ina ya matenda katundu mtima, matenda tizilombo).

Pafupifupi 80% ya ntchito zonse zokhudza mankhwala jini, HIV ndi matenda a khansa. Panopa, akatswiri imachitika ngati matenda otengera monga amapatsira mwana wake B, matenda Gaucher a enaake fibrosis, hypercholesterolemia.

Chithandizo cha matenda majini kumafuna:

· Kusankha ndi kafalitsidwe mitundu munthu maselo mu mtima;

· Malonje a majini yachilendo;

· Kusankha maselo amene "anaona" jini yachilendo;

· Implantation kwa mtima (mwachitsanzo, mwa magazi).

Gene mankhwala zachokera oyamba DNA anaipanga mu zimakhala wodwala. The njira yabwino kwambiri amatengedwa kuti katemera jekeseni ndi aerosol.

Gene mankhwala ntchito m'njira ziwiri:

1. Chithandizo cha matenda monogenic. Zikuphatikizapo chisokonezo mu ubongo imene imakhudzana ndi kuwonongeka kwa maselo yotulutsa timene.

2. Chithandizo cha matenda otengera kwa makolo. Ikuyandikira chachikulu ntchito luso:

· Chibadwa kusintha kwa maselo mthupi;

· Kuwonjezeka immunoreactivity chotupa ndi;

· Block mawu a oncogenes;

· Kuteteza maselo wathanzi kwa mankhwala amphamvu;

· Lowetsani chotupa suppressor chibadwa;

· The yopanga wothandizila odana ndi chotupa maselo wathanzi;

· Yopanga katemera antitumor;

· Local kubwezeretsa kwa zimakhala zachilendo pogwiritsa ntchito antioxidants.

Kugwiritsa ntchito mankhwala jini zambiri ubwino, ndi zina ndi kokha mwayi wa moyo wabwinobwino anthu odwala. Komabe, mbali iyi sayansi asanamvetsetse. Pali lamulo loletsa mayiko pa chiyesedwe cha maliseche ndi chisanadze implantation maselo embryonic. Izi zachitika pofuna kupewa yamanga osafunika jini ndi masinthidwe.

Yopangidwa ndi anavomereza ena mavuto ndi mayesero matenda amaloledwa:

1. Jini anasamutsa m'zipinda chandamale, ayenera kukhala ndi mphamvu kwa nthawi yaitali.

2. Mlendo chilengedwe jini ayenera kukhalabe ndi nchito zake.

3. Gene kutengerapo si chifukwa zochita chowawa mu thupi.

Pali nkhani zosiyanasiyana kuti tikhalebe othandizanso ndi asayansi ambiri padziko lonse:

• Kodi asayansi ntchito m'munda wa mankhwala jini, kukhala genokorrektsiyu wathunthu sadzakhala loopsa kwa mbadwa?

• Kodi kufunika ndi phindu la mankhwala jini amalimbikitsa angapo makamaka kuposa chiopsezo kulowelela ku tsogolo la anthu?

• Kaya njira zimenezi tilungamitsidwa, anapatsidwa kuchulukana kwa dziko m'tsogolo?

• Kodi ikukhudzana njira zofanana pa anthu ndi mafunso homeostasis wa biosphere ndi anthu?

Pomaliza, tisaiwale kuti mankhwala majini pa siteji pano anthu amapereka njira zochizira matenda aakulu kwambiri kuti mpaka posachedwapa ankatengedwa osachiritsika ndipo amapha. Komabe, nthawi yomweyo, chitukuko cha sayansi amachitikira asayansi mavuto atsopano kuti ayenera analankhula lero.