"Pomalidomide" (iminovid): mtengo, zofanana. Kodi kugula Imnovid ndi kotsika mtengo wotani?

Pomalidomide ndi mankhwala omwe ali m'badwo watsopano wa antitumor immunomodulators. Zinthu izi zimatha kuletsa maselo osokoneza bongo, omwe amathandiza chitukuko ndi kukula kwa myeloma. Kuwonjezera apo, zimayambitsa apoptosis (yokonzedweratu imfa ya zoperewera maselo) ndipo imalepheretsa kuchulukana (kuchuluka kwa ziphuphu).

Kafukufuku wasonyeza kuti, chifukwa cha kugwiritsa ntchito pamildomide, mlingo wa kupita patsogolo wafupika ndi 52%, ndipo chiyembekezo cha moyo chimakula kwambiri.

Chida ichi chinavomerezedwa ku United States kuti chithandizo cha multiple refractory ndi kubwezeretsanso myeloma. Kumeneko amaperekedwa pansi pa dzina la malonda "Pomalist", ndipo mu EU amadziwika kuti "Imnovid".

Kodi ndingapeze kuti kukonzekera kotsika mtengo komwe kuli pologidomide

Tisanapitirize kufotokozera zochitika za pamelidomide, ziyenera kunenedwa kuti mankhwala omwe amafunika kuchiza khansa ndi okwera mtengo. Ndipo vuto ndi odwala ndiloti palibe kuthekera kolepheretsa chithandizo, ndipo ndizovuta kwambiri kulipira maphunziro onse. Choncho, ku Moscow chifukwa cha mankhwala osokoneza bongo omwe ali ndi pologidomide, mtengowo umasungidwa m'dera la ruble 819,000.

Pa izi, mutha kuthandiza malo otchuka a www.onko24.com. Pano mungagule zowonjezera zomwe zili ndi mankhwala ofanana - pologidomide, mtengo wa iwo pamene zidzakhala zotsika mtengo kwambiri. Ndipo izi siziyenera chifukwa cha khalidwe losauka la mankhwalawa, koma kuti umboni wotchuka wa Indian firm that produces it did not invest in research, development and advertising. Iye adagula ufulu wokonza mankhwalawa, omwe amafotokoza mtengo wake wotsika mtengo, ndi mphamvu yomweyo.

Njira yogwiritsira ntchito ndi mlingo

Pomalidomide amasonyezedwa pochiza odwala okalamba oposa zaka 18 omwe ali ndi chidziwitso chochulukirapo cha mankhwala osokoneza bongo ambiri a myeloma pambuyo pa mankhwala awiri omwe ali ndi lenalidomide ndi bortezomib.

Ikani mankhwala mkatimo, pamodzi ndi dexamethasone, 4 mg kamodzi patsiku, kwa masiku 21, mutatha kupuma kwa sabata.

Mankhwalawa ayenera kutengedwa nthawi imodzi, tsiku lililonse, mosasamala nthawi ya chakudya. Kufunafuna kapena kuswa capsules sikutheka. Ngati mankhwala amodzi akuphonya, tsiku lotsatira simukusowa kumwa mlingo wambiri wa mankhwala.

Nthendayi ikapitirira, mankhwalawa amaletsedwa.

Contraindications

Osati mankhwala omwe ali ndi pamildomide, ana osakwana zaka 18 ndi amayi oyembekezera. Kuyamwitsa kwa nthawi ya mankhwala ndi mankhwala akuyenera kuletsedwa.

Chikhalidwe cha odwala omwe ali ndi vuto la chiwindi komanso chosafuna kudziletsa ayenera kuyang'aniridwa ndi dokotala yemwe akupezekapo, kuti azindikire nthawi yomwe sakufuna.

Zotsatira zoyipa

Pochita ndi mapulani omwe ali ndi pamildomide (Imnovid, Pomalist, ndi zina zotero), zotsatira zotsatilazi zikhoza kuwonedwa mwa odwala:

• Kuwonjezera kutopa;
• Kupezeka kwa mutu, chizungulire ndi chisokonezo;
• Nsomba, kusanza;
• Kuchepetsa kudya;
• Kusokonezeka kwa kapangidwe ka zakudya;
• Matenda a magazi, thrombocytopenia;
• Kuchitika kwa minofu ya minofu ndi ululu m'mapfupa;
• Kukula kwa matenda opatsirana kumtunda wakupuma;
• Kuwoneka kwa kuthamanga.