MMF (mycophenolate mofetil): kufotokoza, analogs

Mycophenolate mofetil (alendo Mycophenolic acid) ndi mgulu la immunosuppressants. Tiyeni tione mwatsatanetsatane milandu imene m'pofunika kugwiritsa ntchito mankhwala, kodi contraindications ntchito zake ndi zotsatira zake zoyipa.

Komanso, ife tikupeza kuti ngati muli ano mankhwala njira zofanana.

Chidule

mycophenolate mofetil likupezeka mu mawonekedwe a makapisozi gelatin khama minyanga ndi ufa woyera mkati.

Kugula mankhwala pharmacies pokhapokha ngati muli ndi mankhwala kwa dokotala.

Alumali moyo zaka ziwiri amatanthauza. Pitirizani zikhale pa kutentha kwa madigiri 25.

Pofuna kuzindikira zithunzi momwe ife tiganizire maonekedwe mankhwala (mycophenolate mofetil), chithunzi pamwambapa kutumikira Mwachitsanzo fanizo.

mankhwala

Mmodzi kapisozi njira lili 250 mg pawiri yogwira (mycophenolate mofetil). Komanso, panopa ndi wothandiza zigawo zikuluzikulu, monga sodium wochuluka croscarmellose, microcrystalline mapadi, povidone ndi magnesium stearate.

Pharmacokinetics

Pambuyo mankhwala ndi mayamwidwe yake ndi wathunthu presystemic kagayidwe. Pankhaniyi, ndende zinthu mwakhama plasma zimawonedwa chifukwa kusintha kwake mofulumira mu metabolites yogwira.

Kumatanthauza excreted ndi mkodzo ndi ndowe.

zikuonetsa

Nthawi zina, ntchito ya mycophenolate mofetil? Malangizo ntchito mofulumira funso limeneli.

Madokotala mankhwala kutenga mankhwala kwa prophylaxis wa pachimake kumuika kukana odwala pambuyo impso kupatsidwa zina, chiwindi kapena mtima.

contraindications

Palibe nthawi zambiri pamene ntchito ya mankhwala ndi koletsedwa "Mycophenolate mofetil". Zikuphatikizapo pamaso pa hypersensitivity wodwalayo kuti waukulu mankhwala yogwira kapena zigawo zina za wothandizila, komanso ngati ali woyembekezera ndi mkaka wa m'mawere.

The efficacy ndi chitetezo cha mankhwala pa matenda a ana sizinachitike amadziŵika, kotero musati ntchito mu Pediatrics.

zotsatira zoyipazi

Mycophenolate mofetil angathe kuutsa zotsatira zina zoyipa. ntchito zake osakaniza cyclosporine ndi corticosteroids akhoza kutsekula, kusanza, leukopenia ndi sepsis. Nthawi zina, panali chitukuko cha lymphoma ndi malignancies ena, makamaka a khungu.

Komanso, odwala onse kumuika ali pa chiopsezo cha matenda opatsirana, amene chikwiyire ndi tizilombo toyambitsa matenda osiyanasiyana. Ambiri mwa iwo ndi nsungu, candidiasis ndi cytomegalovirus.

Machitidwe ena chowawa akhoza zimapezeka mu mawonekedwe a matailosi, matenda thirakiti mkodzo, rhinopharyngitis, hyperthermia, nthenda chiwindi ntchito, esophagitis, m'mimba magazi, matenda a thirakiti chapamwamba kupuma, kutsokomola, litsipa, gastroenteritis, kutopa, sinusitis, m'kamwa candidiasis , kapamba, pancytopenia, neutropenia, ndi zina zotero.

Pali kuopseza kwambiri ndi zina zochitika woopsa monga TB, endocarditis bakiteriya, matenda atypical mycobacterial.

N'zimene ndi Administration

Kodi kugwiritsa ntchito mankhwala "Mycophenolate mofetil"? Malangizo Ufumuyo amapereka mauthenga awa.

Pakuti kupewa impso kukanidwa. Mlingo woyamba wa wothandizira anayambitsa mu thupi mwa mawola 72 kupatsidwa zina maphunziro. Kenako, wodwala ayenera kutenga 1 g kawiri pa tsiku lake.

Choncho mycophenolate mofetil nthawi kutumikiridwa mu osakaniza corticosteroids ndi cyclosporin.

Pakuti kupewa mtima kukanidwa. Mlingo woyamba ayenera kumwedwa pasanafike 5 Patapita masiku opaleshoni maphunziro. Kenako kofunika kuchuluka kwa mankhwala ndi 1.5 ga kawiri pa tsiku

ambiri osokoneza

Data pa mankhwala ambiri osokoneza bongo, "mycophenolate mofetil," palibe.

Izo zikutanthauza kuti n'zosatheka tikuona m'thupi mwa hemodialysis. Mankhwala kumumanga zidulo ya ndulu (cholestyramine) mwina atsogolere kuchotsa IFC chamoyo wowonjezera excretion ake.

Features ya ntchito

Pa kudziwika ndi neutropenia wodwala ayenera kuchepetsedwa mlingo ndipo kwambiri kuyan'ana udindo thanzi wodwala kapena usokoneze chithandizo mycophenolate mofetil.

Pamaso pa aakulu kulephera aakulu aimpso ayenera kwambiri kuyan'ana ukupeza ndipo alibe upambana munthu pazipita mlingo njira, imene Pankhaniyi chimachititsa 2 ga patsiku.

odwala Okalamba (zaka 65) azimwa 1 g wa mankhwala, nthawi 2 tsiku.

Information za mphamvu ya wothandizila pa matenda a odwala ndi kulephera aimpso amene anakumana ndi chiwindi kumuika kapena mtima, akusowa. Komanso, palibe zokhudza mmene mankhwala othandiza odwala ndi zotupa chiwindi anthu osunga mtima kupatsidwa zina anapangidwa.

kusamala

Mulimonsemo sangathe kutsegula kapisozi kukonzekera. Ayenera kupewa mwachindunji kukhudzana ndi ufa: izo inhalation, kukhudzana ndi khungu kapena nembanemba mucous. Koma ngati izo zinachitika, ayenera yomweyo kusambitsa zinkakhala m'dera ndi sopo ndi madzi.

analogues wa ndalama

Kodi pali mankhwala kuti akhoza m'malo mankhwala "Mycophenolate mofetil"? Analogs, ndithudi, pali. Iwo ndi alendo yemweyo (mayiko Nonproprietary Dzina), kapena ATC code. Kodi kokha yosiyaniranapo sipekitiramu ntchito ndi ndalama ndalama.

Yotchuka kwambiri ndi mankhwala zotsatirazi:

• "Baksmun". Ntchito limodzi ndi cyclosporine ndi corticosteroids kwa kupewa kukana mtima, chiwindi, impso kapena pambuyo kupatsidwa zina.
• "Zenapax." Izo ntchito popewa kukana ndi kumuika impso osakaniza cyclosporine GCS.
• "Imusporin". Ntchito kupewa ndi kuchiza ziwalo kuziika ndi mafupa komanso nyamakazi, amkati uveitis, matenda Behcet ndi zokhudza zonse lupus erythematosus, ndi matenda ena.
• "Imufet". Komanso mankhwala chachikulu, wothandizila kutumikiridwa mu osakaniza corticosteroids ndi cyclosporin pofuna kupewa kukana impso kuziika kapena chiwindi.
• "Layfmun". Chida ali sipekitiramu lonse kanthu. Thiabendazole angagwiritsidwe ntchito popewa ndi kuchiza kukana ziwalo kuziika ndi thupi ndi mafupa, monga nyamakazi, nephrotic syndrome, njira yogwira zokhudza zonse lupus erythematosus, matenda Behcet a, amkati uveitis ndi matenda ena.
• "Mifenaks". Zikuonetsa ntchito ndi zofanana ndi za njira yaikulu.
• "Mifortik". Cholinga chake ndi kuchepetsa kusalandira impso kuziika.
• "Mofilet". Zizindikiro ndi ntchito ofanana ndi mycophenolate mofetil.
• "Panimun". Ntchito kupatsidwa zina za m'mapapo, mtima, impso, mafupa, kapamba, komanso matenda ena.
• "CellCept." Iwo akhoza anatumizidwa pamene impso kumuika.
• "Sertikan". Iwo anasonyeza kuti impso kumuika kapena odwala mtima ndi zolimbitsa kapena otsika chiopsezo immunological.
• "Tsikloral". Ntchito limodzi ndi mankhwala ena kuziika ziwalo.
• "Ekvoral". Izo ntchito mu kupatsidwa zina ziwalo parenchymal, komanso kupewa kukana pambuyo kupatsidwa zina.

Ngakhale kuti iwo onse ndi mtundu wofanana wa kanthu, pamaso kuchotsa mankhwala chachikulu china chilichonse, muyenera kaye, ndi kukaonana ndi dokotala.