Mankhwala kwa ziphuphu zakumaso pa nkhope, "Roaccutane": ndemanga, zithunzi isanayambe kapena itatha malangizo

Aliyense wachinyamata pa unamwali vuto la ziphuphu zakumaso kapena mawonetseredwe sayansi ya ziphuphu zakumaso. Wina mosavuta kuthandiza kuti njira zodzikongoletsera ndi kanthu maganizo. Anthu mwai awa onse a matenda a khungu si bwino. Zodzikongoletsera zopindika mawonekedwe a blackheads, ziphuphu ndi zipsera iwo apitiriza bwino mpaka akakula. Pankhaniyi, munthu zochita osati thupi, komanso waukulu maganizo nkhawa. Mavuto ndi khungu kusokoneza Suopa ndi kwathunthu tizisangalala ndi moyo. Pa nthawi imene ena onse njira kulamulira kusonyeza n'zachabechabe awo, madokotala mankhwala mankhwala odwala "Roaccutane". Reviews, zithunzi pamaso ndipo pambuyo chithandizo ndi mankhwala awa kuyambitsa mapeto a dzuwa awo okwezeka. Komabe, Dziwani kuchuluka kwa mavuto ndi kufunika nthawi kuwunika magawo amuzolengedwa magazi wodwalayo.

"Roaccutane" udachita ndemanga zabwino madokotala. Akatswiri amanena: pakalibe contraindications, komanso mogwirizana mtheradi ndi malangizo onse a wodwalayo kwambiri achire ndi zodzikongoletsera kwenikweni.

Kodi mankhwalawa?

"Roaccutane" - ndemanga piritsi lomwe makamaka zabwino njira - ndi pokonzekera mankhwala mwachindunji ziphuphu zakumaso ndi blackheads. makapisozi izi zili zofiira hue kuyimitsidwa, mbali yaikulu ya ndilo isotretinoin mu kuchuluka kwa 10 mg kapena 20 mg (malingana ndi mitundu kumasulidwa). Powonjezera kukonzekera retinoid limapangidwa zigawo zina, Pakati soya mafuta, phula, glycerol, gelatin, wowuma mbatata ndi utoto zosiyanasiyana chakudya khalidwe. "Roaccutane" akusonyeza zochizira mitundu choopsa cha ziphuphu zakumaso kuti sangathe kuchiritsidwa ndi njira zinazi.

Monga ntchito mankhwala?

Chidwi mfundo: madokotala akadali ndiribe asanaganize limagwirira yeniyeni kanthu "Roaccutane" mankhwala. Reviews, zithunzi pamaso ndipo pambuyo chithandizo ndi wothandizila izi kuuzira madokotala ambiri amalangiza odwala awo ndi chitsanzo zovuta za ziphuphu zakumaso. Isotretinoin, ndilo stereoisomer Trans-retinoic asidi, ali zotsatira izi pa thupi la munthu;

• kumabwezera mmbuyo ntchito yambiri pa zopangitsa za sebaceous.

• achepetsedwa awiri.

• Kodi odana ndi yotupa tingati pa khungu.

N'chifukwa chiyani ziphuphu zakumaso anapanga?

The epithelium okuta tsitsi babu, limakula ndi exfoliated. Maselo izo corneocytes, losindikizidwa ritsa khansa keratin ndi sebum. Zimenezi zimabweretsa mapangidwe comedones, kenako ubwenzi wa munthu amene yotupa. Sebum ndi ankakonda kukula sing'anga ndi kubalana mtundu Propionibacterium acnes mabakiteriya. Iwo ali prerequisites chachikulu zikamera mawanga angapo, redness ndi zochitika zina zosasangalatsa m'nkhaniyi.

Mankhwala "Roaccutane" amakambirana kuti madokotala umboni, dermatologically anatsimikizira mphamvu yake kupondereza kuchuluka kwa sebocytes. Iko kumabwezeretsa mlingo physiologically yachibadwa zosiyanasiyana maselo zaminyewa. "Roaccutane" kumachepetsa ntchito sebum chotero kukula kwa bakiteriya ndi anaima, kutupa chikutha zabwino zodzikongoletsera zotsatira zimatheka.

Kodi pharmacokinetics za mankhwala?

Isotretinoin imatsala kwa mundawo m'mimba, ndi ndende pazipita ndi wapezeka magazi mu maola 2-4 pambuyo utsogoleli. Pali zina zimene zili ntchito "Roaccutane" mankhwala. Reviews kulola akatswiri kupanga mfundo yotsatirayi: phale ndi bwino kumwa pambuyo chakudya. Izi kumawonjezera bioavailability wa isotretinoin mu nthawi 2 poyerekeza ndi phwando mankhwala pa chopanda kanthu m'mimba.

Waukulu yogwira pophika ndi chimango yonse zonsezo magazi ndipo zimapukusidwa kupanga mankhwala zinayi zikuluzikulu. Anasonyeza isotretinoin ndi metabolites ake mu mkodzo ndi ndowe pa nyengo ya maola 19 kuti 29. Kubwezeretsa okhutira thupi la retinoids anthu zikadzatha masabata 2 kumapeto kwa njira mankhwala.

Kodi mlingo kuti makhwalawa?

About zochuluka bwanji kutenga "Roaccutane" (mapiritsi), mukhoza kumva mayankho osiyana. Tikumbukenso kuti muyezo ichi chokha chimene chinakhazikitsidwa ndi dokotala kupezeka potengera zochitika payekha alili.

The medicament "Roaccutane" mavoti, chithunzi pamaso ndipo pambuyo chithandizo, zomwe anatsimikizira Mwachangu ake okwezeka, nthawi anatengedwa kamodzi kapena kawiri pa tsiku pakamwa.

Kukhalapo kwa mphamvu ya mankhwala, ndi mavuto zimadalira boma woyambirira wa wodwalayo ndi mlingo kutchula. zinthu izi ulembedwe munthu njira kwa momwe mankhwala mankhwala "Roaccutane". Reviews madokotala amati kuyambira nthawi zonse bwino ndi mlingo osachepera amene masamu anapangira 0.5 mg wa isotretinoin pa makilogalamu 1 kulemera mtima thupi kwa maola 24. Malinga ndi kafukufuku, avareji chiwerengero cha prescribers - 0.5-1.0 mg / kg pa thupi patsiku. Ngati mlingo wa ziphuphu zakumaso wodwalayo amakhala ngati zovuta, ndiye kuti anatuma mlingo waukulu - kuti 2.0 mg / kg pa patsiku. Komanso, mu milandu kuyamba ndi pang'ono - 10 mg / tsiku ndipo ngati n'koyenera, kuchuluka kwa 1 mg / kulemera makilogalamu thupi pa maola 24.

Pali mulingo woyenera kamwedwe "Roaccutane" wa ziphuphu zakumaso mankhwala. Reviews madokotala akusonyeza kuchuluka kwa mankhwala 120-150 mg / kulemera makilogalamu thupi, ndi anagawira pa njira yonse. Choncho, nthawi ya chithandizo kumatengera ankafuna mlingo tsiku la mankhwala. Kawirikawiri kwa nthawi ya masabata 16-24 n'zotheka kukwaniritsa chithunzi pafupifupi kwathunthu kwa chikhululukiro cha ziphuphu zakumaso. Ngati wodwala amanyamula anasankha zoipa phwando chiwembu, mlingo tsiku anali amachepetsa ndi kuonjezera nthawi ya mankhwala.

Kwenikweni, ndithudi mmodzi wa mankhwala "Roaccutane" mankhwala - ndemanga, zithunzi isanayambe kapena itatha kutsimikizira mfundo imeneyi - zokwanira mofulumira wathunthu wa ziphuphu zakumaso. Komabe, ngati wodwalayo kusuta bwino, adokotala akhoza mankhwala yachiwiri achire nthawi. Pankhaniyi, mlingo ndi nthawi ya mankhwala ndi mankhwala akhala sichinasinthe.

Kutalika kwa zotsatira zodzikongoletsera, yomwe mapiritsi a ziphuphu zakumaso pa nkhope yake, "Roaccutane" ayankhe madokotala ndi odwala amatchula masabata 8. Choncho, panafunika kukonzanso chithandizo zimaonekera pokhapokha nthawi ino ndipo osankhidwa.

Kodi pali ambiri osokoneza?

Ngati wodwala kuposa mlingo pamene mukumwa mankhwala "Roaccutane", malangizo ntchito, pamene umboni uperekedwa mtima kuloza kwa zikamera wa zizindikiro za hypervitaminosis mu vitamini A. Izi likuchotsedwa posambitsa m'mimba, chimene chili chofunika n'kupatsa maola ochepa choyamba pambuyo mankhwala chochitika cha ntchito kwambiri.

Mankhwala interacts ndi mankhwala ena?

Munthawi yomweyo phwando "Roaccutane" ndi vitamini A kumabweretsa hypervitaminosis watha, kotero kuphatikiza ayenera kuzipewa.

Contraindicated osakaniza mankhwala ndi isotretinoin ndi tetracyclines, monga imbaendesa ndi kuwonjezeka mu kuthamanga intracranial.

Nthawi zambiri, kuchepetsa mphamvu ya progesterone, zomwe zimabweretsa ziphuphu zakumaso mankhwala "Roaccutane". Reviews madokotala akusonyeza kuti mankhwala a chida ayenera kugwiritsidwa ntchito mapiritsi kulera zosiyanasiyanazi ndi milingo apamwamba timadzi ndi njira ntchito chotchinga cha kulera.

Ngati wodwala amagwiritsira ntchito mankhwalawa "Roaccutane" m'dera wothandizila keratolytic kapena exfoliants, kungakhale mkwiyo wa khungu.

Kodi n'zotheka ntchito mankhwala kwa amayi apakati?

"Roaccutane" (mapiritsi, ndemanga imene ouziridwa ambiri mayeso mogwira mtima kuti mudziwe) ali ndi mbali yofunika kwambiri: iwo mwamtheradi contraindicated pa mimba. Isotretinoin ali amphamvu teratogenic. Chithandizo, ngakhale mlingo lalifupi ndi ang'ono ndi Mwina mkulu zingachititse kwambiri malformations yoopsa.

Chimenechi ndi chifukwa contraindication la mankhwala kwa akazi wobereka zaka amene satsatira mfundo zotsatirazi:

• Kupezeka kwa mawonekedwe choopsa cha ziphuphu zakumaso kuti si inathetsedwa ndi mankhwala ochiritsira.

• Mzimayi mwangwiro amamvetsa ndipo complies ndi malangizo onse a dokotala.

• Iye anauza dokotala za kuopsa mimba pa mankhwala "Roaccutane" ndi mwezi zitachitika izo, kufunika ndi upo mwadzidzidzi katswiri pa mwambo mfundo mimba.

• Mzimayi amadziwa kuchepetsa kapena kutayiratu mphamvu ya kulera.

• Iye amadziwa chofunikira ndi kufunikira kwake kwa dokotala mwachindunji zodzitetezera.

• Mkazi akumvetsa kufunika otetezeka ku mimba m'kati mwa mankhwala, mwezi isanayambe kapena itatha iye, komanso kufunika kogwiritsa ntchito onse njira 2 kulera (kuphatikizapo chotchinga).

• Mayi ali oipa mimba chifukwa mayeso amene ayenera analandira mwa masiku 11 isanafike mankhwala. Komanso, mpheto ayenera anachita pamwezi pa mankhwala ndi 5 masabata pambuyo kutha.

• Ndi ayenera kuyamba kulandira mankhwala yekha kwa maola 2-3 zotsatirazi yachibadwa msambo.

• Mzimayi kwenikweni ayenera kukaonana ndi adokotala mwezi uliwonse.

• Onse katundu pamwamba ndi zogwirizana maphunziro mobwerezabwereza mankhwala "Roaccutane".

Onetsetsani kuti kuphatikiza kulera odalirika ndi "Roaccutane" yothetsera ziphuphu zakumaso. Akatswiri alendo amanenanso za kufunika kwa kusunga malamulo okhwima ndi akazi onse, ngakhale amene samatenga kulera chifukwa cha osabereka, amenorrhea, ndipo sadzalola kuti zachiwerewere. Musakhale yekha wodwala amene anali akukonza hysterectomy.

Kodi tiyenera kukumbukira adokotala?

dokotala ayenera kudziwa mfundo zina za mtima pamaso chithandizo zoika ake "Roaccutane". Mlendo Akatswiri amanena kuti pofuna kupewa zochitika zadzidzidzi, dokotala ayenera kukhala wotsimikiza mwamtheradi zokhudza malo awa:

• Wodwala kwenikweni aakulu mtundu wa ziphuphu zakumaso kuti sangathe kuchiritsidwa ndi njira zina za mankhwala, ndicho nodulocystic kapena konglobatnye zochitika zotsogolera ku amamuyambitsa timabala.

• Amayi ndi zoipa chifukwa mimba mayeso amene anatengedwa pamaso pa njira ya chithandizo, milungu mankhwala ndi 5 nditamaliza ake. deta Zonsezi ndi umboni wa tsiku kusanthula ndi mosamalitsa zalembedwa.

• Wodwala kwenikweni likukhudza kulera (1, ndipo makamaka 2), njira chotchinga chofunika. lamulo limeneli likukhudza kwa miyezi pamaso chithandizo, ndithudi ndi masiku 30 pambuyo mankhwala.

• Mzimayi amamvetsa kufunika kutsatira miyezo popewa mimba.

• Wodwala akukumana onse a muyezo tatchulazi.

Makamaka kupanda kuwunika mimba

Tikumbukenso kuti mimba mayeso, tilinazo 25 yodziwika mME / ml, m'pofunika n'kupatsa masiku 3 kuzungulira kusamba.

Pamaso pa njira ya mwezi wodwalayo ayenera kuyamba kutenga za kulera zosiyanasiyanazi. Mimba mayeso pa tsiku la atasankhidwa, "Roaccutane" tsiku ake ndi dokotala zotsatira olembedwa zalembedwa.

Pa mankhwala, wodwalayo ali wofunikila kukaona dokotala aliyense masiku 28 ndi cheke kuvomerezedwa pakalibe mimba. Mayeso omwewo ikuchitika pambuyo masabata 5 mapeto a mankhwala.

"Roaccutane" mtima umboni umene kulankhula za zotsatira zake zabwino zodzikongoletsera, amasankhidwa ndi mankhwala okhaokha kwa masiku 30. Ngati mukufuna kupitiriza mankhwala Ndi bwino kubwereza mimba mayeso.

Kodi ndizimwa makhwalawa amuna?

Ziphuphu zakumaso chithandizo kwa anthu mankhwala "Roaccutane" n'koyenera, koma wodwala ayenera kusamalira kuti achotse kuvomera mankhwala ndi anthu ena. Padzuwa la mankhwala mu madzimadzi seminal ndi otsika ndi sangathe kusonyeza katundu teratogenic.

M'mene angakonzekere mimba?

akazi ambiri nkhawa mmene mimba adzatuluka pambuyo "Roaccutane". Reviews madokotala zikusonyeza kuti kukonzekera lingaliro akhoza kuyamba palibe kale kuposa mwezi umodzi pambuyo pa mapeto a kwathunthu mankhwala.

Ngati mogwirizana ndi malangizo onse mimba ndi nthawi yoopsa, mkazi ayenera kudziwa kuti kuli chiopsezo osauka fetuses aakulu CNS pathologies a dongosolo mtima, nkhope ndi zopangitsa za endocrine. Choncho, analankhula nkhani yosungira mwanayo.

Mankhwala "Roaccutane" sayenera kumwedwa ndi amayi pa mkaka wa m'mawere, monga chitadutsa mu mkaka wa m'mawere.

zotsatira zake chowawa angayambe?

Pali kwambiri ambiri mavuto omwe angagwe mu wodwalayo ntchito "Roaccutane" mankhwala. Malangizo, ndemanga madokotala ndi odwala amatchula zotsatirazi zotsatira osafunika:

• Depression, kuthamanga intracranial, kupweteka kwa mutu, khunyu.

• Kuchepetsa zovuta usana ndi madzulo masomphenya, matenda diso, kumva kuwonongeka.

• Kuphwanya wa chopondapo, nseru, yotupa matenda matumbo, kapamba, magazi.

• kuchepa magazi, kusintha achiyesa kupatsidwa zinthu za m'mwazi, erythrocyte mlingo sedimentation, hematocrit, neutropenia ndi leucopenia.

• bronchospasm.

• Kumva kupweteka mfundo ndi minofu, hyperostosis, tendonitis, nyamakazi.

• totupa, erythema, kuyabwa, thukuta, mtundu, kupatulira ndi tsitsi imfa, photoallergy.

• kuuma khungu ndipo zimagwira ntchito zosiyanasiyana mucous cha milomo, mphuno, pharynx ndi m'phuno, maso.

• Kusintha magawo zasayansi: kulera mlingo wa mafuta m'thupi, triglycerides, lipoprotein, hyperglycemia.

• zokhudza zonse kapena m'dera streptococcal matenda.

• hematuria, vasculitis, hypersensitivity, lymphadenopathy.

• Stevens-Johnson syndrome, erythema multiforme poizoni epidermal necrolysis.

Izi mankhwala contraindicated?

Mankhwala "Roaccutane" ali contraindicated matenda otsatirawa ndi zikhalidwe:

• Hyperlipidemia mtundu mawu.

• Mimba ndi mkaka wa m'mawere.

• Hypervitaminosis A.

• Therapy ya tetracycline mankhwala.

• Chiwindi kulephera.

• Kuchuluka mlingo wa kudziwa mankhwala.

• Ana mpaka zaka 12.

Mosamala yogwira mankhwala kutumikiridwa kwa wodwala ndi shuga, uchidakwa, matenda zamadzimadzi, maganizo ndi kunenepa.

Mphamvu ya mankhwala si chipeneko. "Roaccutane", ndemanga, zithunzi ndi zidindo zimene umboni zosafanana achire ndi zodzikongoletsera mawonetseredwe ake, kukhulupirira pochiza ziphuphu zakumaso, ngakhale mitundu aakulu. Komabe, kudziwa mavuto onse kumbali ya mankhwala amene ndi yosemphana ndi mimba ndi mkaka wa m'mawere, komanso pamaso pa angapo contraindications. Cholinga cha mankhwala ino yokha ndi dokotala nawo, amene anaika munthu wodwala mlingo ndi nthawi ya mankhwala.