Vasodilator - ndichiyani? Kufotokozera za gulu pharmacological

Vasodilation ndi ndondomeko zosangalatsa za wosanjikiza minofu ya linga mtima. Mankhwala kukhala limagwirira chimodzimodzi kanthu ndi ntchito pa matenda a matenda a mtima ndi matenda oopsa, wotchedwa lolingana akuti - vasodilator. Kodi izo ndi zimene zipangizo ndi vasodilators, tiganizire moposera.

mwachidule

Yafupika mtima linanena bungwe, osauka mtima kulephera, akuziyambitsa dongosolo adrenergic mantha ndi renin-angiotensin, chifukwa mu amasulidwe angiotensin II ndi norepinephrine. yogwira kumumanga kwa maselo a, imbaenda vasoconstriction.

Gawo loyamba la kulephera mtima umafuna limagwirira zimenezi, chifukwa timatha kukhalabe kufunika magazi. Komabe, nthawi yaitali kuchepetsa wa mitsempha yopita ku chitukuko cha njira congestive mu mapapo ndi kuchepa linanena bungwe mtima.

Vasodilators - mankhwala (mndandanda wa maudindo angapezeke mu mabuku apadera zachipatala ndi pharmacological Komanso pansipa tikungotchula njira yotchuka kwambiri ya gulu ili), ntchito chifukwa cha kukula kwa mitsempha. Chifukwa ndi chitukuko cha zotsatira hypotensive. umboni wina ofunika mtundu wa mankhwala ndi atsimikize chifuwa. Kodi ngati chikhalidwe kudzakuthandizani vasodilators? Kukonzekera pa chifuwa mtima ntchito kukuza ziwiya inatsekeratu.

gulu la mankhwala

Malinga ziti pa bedi mtima anakhudzidwa ndi surfactants, pali magulu atatu a vasodilators:

1. wolumikizira:
   • "Hydralazine";
   • kashiamu muzikangana.
2. venous:

• ku feteleza;
• sydnonimine.

vasodilators Venous

Venous vasodilator - ndichiyani? Izi zimayambitsa mankhwala utachepa kamvekedwe wa venous mtima khoma. Venules kuyankha woipa apansi yogwira kuposa mtsempha wamagazi ndi. Zikatero, ku feteleza ntchito kumasuka mitsempha yaikulu, kuwonjezera m'magazi, kuchepetsa katundu mtima, kuchepetsa kufunika m'mnyewa wamtima kufunika oxygen.

Venous vasodilators - kukonzekera (maina, Mlingo yafotokozedwa mu tebulo), amene ankaona otetezeka la mankhwala antianginal. Zotsatira zake zoyipa n'zochepa ndi sakhalitsa.

vasodilators wolumikizira

Wolumikizira vasodilator - ndichiyani? Izi pharmacological woukitsa mankhwala yomwe pansi minofu minofu pa khoma wolumikizira.

Mwachitsanzo, "Hydralazine" - mankhwala kumawonjezera mlingo mtima, kuchuluka magazi impso ndi ubongo pali reflex achire zimene kuphipha mtima. Ntchito zosiyanasiyana matenda oopsa, hypertensive mavuto limodzi ndi nthumwi zina.

Zotsatira zoyipa "Hydralazine":

• cephalalgia;
• redness a nkhope;
• kuoneka edema;
• kudzitsitsa maonekedwe a angina;
• chikhalidwe ofanana zokhudza zonse lupus erythematosus.

"Diazoxide" - ndi vasodilator, amene ntchito yokhayo yotumikira thandizo zamavuto hypertensive. M'nsinga, Sachita magazi pambuyo mphindi 2-3. Komanso, wothandizila amachititsa ufulu wosankha amphamvu a chiberekero ndi madzi posungira.

Kashiamu muzikangana - gulu la vasodilators wolumikizira, womwenso njira zotsatirazi:

1. "Nifedipine" - amachotsa ndi kuphipha ziwiya inatsekeratu, Sachita magazi, kumachepetsa ntchito ya minofu mtima.
2. "Verapamil" - kumachepetsa m'mnyewa wamtima contractility, limabwezeretsa mungoli mtima ndi kuthamanga kwa magazi.

Kukonzekera obwerawa Mtundu

Obwerawa vasodilator - ndichiyani? Izi zikutanthauza yogwira pophika amene relieves kuphipha ya mitsempha ndi mitsempha. Mmodzi wa yabwino kwambiri ndi sodium wochuluka nitroprusside. Limagwirira kanthu ndi yofanana ndi ku feteleza. Dongosolo mtsempha wa mankhwala amayambitsa zotsatira mofulumira ndi mwamphamvu, koma nthaŵi yochepa.

Izo ntchito monga vasodilator ngati pachimake ndi aakulu kulephera mtima, boma hypertensive pa maziko a infarction m'mnyewa wamtima, hypertensive encephalopathy ndi zizindikiro. Mawu oyamba a nitroprusside ndi sodium zingachititse chizungulire, kupweteka kwa mutu, imfa ya chikumbumtima, nseru, tachycardia.

Ace zoletsa - gulu zikutanthauza kutsekereza mapangidwe angiotensin akatembenuka enzyme, potero sangabereke angiotensin II. Mu yomweyi, pali kulimbikitsa zotsatira za okodzetsa. Gulu la zoletsa Ace zachokera mankhwala kapangidwe awo:

1. Munali sulfhydryl gulu:
   • "Captopril".
   • "Zefenopril".
   • "Benazepril."
2. A gulu carboxyl:
   • "Lisinopril".
   • "Enalapril".
   • "Spirapril".
3. Phosphinyl gulu okhala ndi:
   • "Fosinopril".

formulations ali ndi ubwino kwa asymptomatic kumanzere yamitsempha yamagazi kukanika, atherosclerosis a mitsempha carotid, matenda kagayidwe kachakudya, microalbuminuria, matenda fibrillation, m'mnyewa wamtima infarction, nephropathy, si matenda ashuga.

ana vasodilators

Vasodilators, mankhwala ana akugwiritsidwa kokha mu pathologies kwambiri. Monga amagwiritsidwa ntchito njira myotropic ( "Dibazol" "Papaverine") ndi ganglionic ( "benzogeksony").

Ana alandire vasodilators mankhwala osokoneza bongo. ndalama ndi umalimbana aziyenda bwino ubongo magazi, ntchito mu "woyera" hyperthermia ndi hydrocephalus.

Aliyense wa mankhwala amasankhidwa payekha, malinga ndi mmene wodwalayo, zovuta kuyan'anila, mawonekedwe ndi zochita matenda. Self-mankhwala osavomerezeka.