Mikoflyukan: malangizo ntchito

mawonekedwe mlingo

Kukonzekera "Mikoflyukan" malangizo chomwe chili m'munsimu akhoza kupangidwa mwa mawonekedwe a mapiritsi woipa zosiyanasiyana za mankhwala yogwira kapena mu mawonekedwe a njira yothetsera kulowetsedwa. mapiritsi mwayera, kuzungulira mawonekedwe ndi pang'ono bevelled m'mbali.

Mapiritsi munali 50 mg wa mankhwala yogwira mbali Chidwi «F», ndi pa zina - "50". The piritsi mawonekedwe "Mikoflyukan" 150 mg wa yogwira pophika - «F150» ndi mzere wolekanitsa, motero.

Kukonza njira ndi colorless, mandala, popanda particles iliyonse.

Zikuchokera: Mapale

Yogwira mankhwala: fluconazole - 50/150 mg (1 tsamba.).

Excipients:

- pakachitsulo woipa ,

- lactose,

- povidone,

- mankhwala enaake a stearate

- Valium,

- talc,

- mapadi mikrokristallicheskayae

yankho

Yogwira mankhwala: fluconazole - 2/200 mg (1 ml vial 1, motero).

Excipients:

- Madzi a jekeseni,

- sodium kolorayidi.

The kanthu pharmacological mankhwala "Mikoflyukan"

Guide limanena kuti kukonzekera ikugwilizirana ndi wothandizila antifungal wa otumphukira triazole. Fluconazole ziletsa ergosterol kaphatikizidwe motere: Iwo amapereka permeability wa pakhoma selo. The mankhwala ndi yogwira motsutsana Microsporum, candida, Trichophyton, Cryptococcus neoformans.

Nkhani ina kanthu pharmacological mankhwala ndi kuti onse kusankha woletsa wa cytochrome P450 mu bowa, koma pa nthawi yomweyo, sangosonyeza ntchito iliyonse motsutsana ndi dongosolo enzyme anthu.

Pharmacokinetics

mankhwala bwino chosakanikirana pambuyo makonzedwe, ndi kudya chakudya molumikizana ndi kutenga mankhwala sikumangotikhudza mayamwidwe ake. Bioavailability - 90%. mankhwala ndi inafalitsidwa kwa ziwalo zonse ndipo zimakhala za thupi. Choncho ndende wake plasma ndende ofanana ziwalo izi ndi zimakhala: olowa madzimadzi, mkaka wam'mawere, malovu, ukazi, sputum ndi madzimadzi perinatal, ndi cerebrospinal madzimadzi bioavailability akhoza zosiyanasiyana, kuyambira 50 mpaka 90%.

Komanso, ziwalo zina ndi zimakhala za ndende mankhwala akhoza kupitiliza ndende mu madzi a. Pakati pawo, ndi khungu, ndi dermis, ndi stratum corneum, thukuta madzi. Hafu ya moyo - pafupifupi 30 maola.

Zikuonetsa ntchito mankhwala "Mikoflyukan"

Malangizo limanena kuti mankhwala ali ndi ntchito yapamwamba ndi tizilombo matenda otsatirawa, omwe sachedwa matenda a mafangasi:

• zokhudza zonse candidiasis,

• cryptococcosis,

• mucosal candidiasis,

• ukazi candidiasis,

• kupewa matenda a mafangasi

• mycoses khungu,

• onychomycosis,

• pityriasis versicolor,

• parakoktsidiovikoz,

• coccidioidomycosis,

• pistoplazmyuoz,

• sporotrichosis.

Zotsatira zoyipa za mankhwala "Mikoflyukan"

Ndemanga za gulu mayeso pambuyo mndandanda wa maphunziro a mankhwala, kuphatikizapo placebo-mayeso ndi njira zina za kafukufuku wasonyeza kuti mankhwala akhoza kukhala otsatirawa mavuto:

- chikutanthauza pa mundawo m'mimba:

• ululu m'mimba,

• nseru,

• flatulence,

• m'mimba;

- mudziko la chapakati ziwalo mantha dongosolo:

• chizungulire,

• mutu;

- chokhudza thupi lawo siligwirizana:

• zochita anaphylactic wa chamoyo,

• ziwengo.

Contraindications mankhwala "Mikoflyukan"

Malangizo kwa mankhwala limanena kuti contraindications ku phwando ake ndi laling'ono mokwanira, pakati pawo:

• mpaka 1 chaka,

• pregnancy,

• kudziwa pawiri triazole ndi fluconazole.

Mwanjira mankhwala

Prothrombin nthawi ukuwonjezeka pamene ntchito mankhwala anticoagulant coumarin mtundu.

Opangidwa kuchokera kwa sulfonylurea wothandizila m'kamwa hypoglycemic kwambiri kuonjezera awo theka moyo anakumana ndi fluconazole.

Fluconazole theka moyo nthawi yafupika pamene analankhulana ndi rifampicin.