Mankhwala "Arlette": malangizo ntchito, contraindications, zikuchokera ndi ndemanga

Kamodzi chitukuko penicillin yosavuta anakhala limathetseratu vuto lina lililonse kwa chiwerengero cha matenda bakiteriya kuti anthu nthawi zambiri anafa. Kuyambira pamenepo, anthu ankalambira mu Zakachikwi wina, ndipo ali ndi chiwerengero cha mankhwala antibacterial monga yotakata-sipekitiramu, ndipo timaganizira kupsyinjika iliyonse ya bakiteriya. Wina chida amenewa ndi "Arlette". kugwiritsa ntchito bukuli mankhwala kakunena mabuku za katundu wake onse.

The zikuchokera wothandizila antibacterial

The Gawo ali amoxycillin trihydrate (masamu monga amoxicillin zotheka mabuku 250, 500, 875 mg) ndi clavulanate potaziyamu (buku - 125 mg, zochokera chidulo clavulanic). Mbali yoyamba amatchedwa mndandanda wa penicillin semisynthetic, yodziwika ndi munda lonse za ntchito antibacterial. The chachiwiri lalikulu zikuluzikulu za medicament ali woletsa sizingasinthe wa beta-lactamases.

Komanso, ambiri mwa zigawo wothandiza ndiwe wa mankhwala "Arlette". Malangizo ntchito, ikulongosola za kukonzekera wabweretsedwa kwa anthu ogula kuti alipo mu zikuchokera otsika maselo kulemera pakati povidone, wowuma pregelatinized, calcium stearate, microcrystalline mapadi ndi talc. Ndipo si onse.

The casing aumbike mankhwala hypromellose, propileglikol ndi polyethylene glycol 4000 (macrogol kapena 4000), titaniyamu woipa. Misa zomvetsera «Arlette" mapiritsi (malangizo Buku limapangidwa mfundo) 600 1100 kapena 1600 mg.

pharmacodynamics

Monga tanena kale, "Arlette" ndi zovuta za amoxicillin ndi asidi clavulanic. Mitundu yamasika khola inactivated zovuta ndi beta-lactamases (bakiteriya michere Ntchito yaikulu imene imakhala kulimbana beta-lactam mankhwala, lofalitsidwa koposa ntchito antimicrobial Morning - cephalosporin, penicillin, etc ...). Beta-lactamases ali ndi udindo kwa chilengedwe cha kutsutsidwa kulimbikira kwa zipangizo zatchulidwazi zachipatala.

Palokha, asidi clavulanic, amene kapangidwe ndi ofanana kuti mankhwala beta-lactam, yodziwika ndi m'malo ofooka antibacterial luso mwini. Komabe, pamaso pa asidi mu "Arlette" amoxycillin chiphunzitso chimatsutsana chiwonongeko ndi kuonjezera dera mwayi antibacterial, kuphatikizapo mmenemo mabakiteriya ndi tizilombo kuti ndi kugonjetsedwa ndi muyezo zinthu chikoka amoxycillin, njira zina za magulu a penicillin ndi cephalosporins.

Mankhwala "Arlette" malangizo ntchito monga medicament ndi nthawi lonse kukhudzana m'dera. Iye akugwira ntchito ndi atengeke mitundu amoxicillin (osati kupatulapo amene lithe beta-lactamase). Zikuphatikizapo osiyanasiyana galamu HIV ndi galamu alibe aerobic mabakiteriya ndi anaerobic.

Zikuonetsa "Arlette" njira

Field anachita nthumwi antibacterial m'malo lalikulu, ndi mogwira angapo osiyana matenda etymology. "Arlette" malangizo ntchito amalola ntchito kuthetsa mavuto ndi chapamwamba kupuma thirakiti thirakiti chapamwamba kupuma. Makamaka tikulankhula za mitundu pachimake ndi aakulu a sinusitis ndi otitis TV, ndi zilonda zapakhosi, pharyngitis, abscesses m'dera retropharyngeal. Impact zabwino medicament ndi zochizira matenda ali dongosolo m'munsi kupuma, monga matenda (aakulu pachimake, limodzi ndi superinfection bakiteriya) ndi chibayo.

Komabe, si malo onse kumene Arlet ntchito. Malangizo ntchito, malongosoledwe mankhwala anenapo nchito zake pa matenda a matenda a dongosolo genitourinary ndi ziwalo m'chiuno. matenda monga pyelonephritis, prostatitis, urethritis, endometritis ndi vaginitis bakiteriya, mimba septic, chinzonono ndi mamita P..

Komanso ndithu anakopa maantibayotiki pa matenda a khungu ndi minofu zofewa matenda osiyanasiyana (abscesses, cellulitis, erysipelas, impetigo, namkulunga, pamwamba ndi kukonzanso kachilombo dermatoses matenda). "Arlette" angagwiritsidwe ntchito pa matenda a mafupa ndi connective zimakhala, biliary thirakiti prolechivanii (cholecystitis, cholangitis), mu zotupa odontogenic, pofuna kupewa njira yotupa mu opareshoni, nthawi postoperative.

Mlingo ndi njira ya ntchito

Mankhwala "Arlette" njira ya ntchito ndi mlingo atsimikiziridwa payekha ndipo amadalira m'badwo, kulemera, chikhalidwe cha impso kwakukulu ndi matenda. Pofuna kuchepetsa mosavuta mavuto pa mundawo m'mimba, phale ayenera kumwedwa pamaso chakudya wonse, musati kutafuna ndi kumwa madzi.

Odwala pa zaka 12 kapena ndi thupi la makilogalamu 40 ndi kuwala chowongolera matenda mitundu kutenga piritsi limodzi (250 mg ya mbali yaikulu) katatu pa tsiku kapena kawiri pa tsiku (500 mg amoxycillin). Mu kuvulala aakulu kutenga muyezo lofanana 500 mg wa amoxicillin katatu tsiku kapena 875 mg - kawiri pa tsiku.

Odwala zaka 6 mpaka 12 "Arlette" malangizo Buku akuonetsa, potengera kulemera kwa 1 makilogalamu amoxycillin - 20-30 mg wa Clavulanic asidi - 5-7.5 mg. Nthawi zambiri, mlingo odwala awa ndi piritsi 1 (250 mg) kawiri kapena katatu pa tsiku kapena piritsi 1 (500 mg) kawiri pa tsiku. Zikavuta, mlingo akhoza kawiri.

Kwa odwala ndi impso ntchito mkhutu mu mlingo ndi dosing pafupipafupi ndi kusintha malinga ndi chilolezo cha creatinine. Amene amadwala anuria, intervals pakati chakudya ayenera ziwonjezeke kwa maola 48 kapena kuposa. Kwa odwala likufa hemodialysis, kuchuluka kwa medicament osankhidwa mlingo pazipita amoxycillin.

Anthu olumala mu ntchito kwa chiwindi ndi kusamala mu mankhwala "Arlette". Malangizo ntchito (umboni), ndemanga ya madokotala analimbikitsa mosalekeza kuyan'ana mkhalidwe wa thupi.

Kwa odwala achikulire banjali mlingo chofunika.

zotsatira zoyipazi

mndandanda zosonyeza mavuto zikuphatikizapo mankhwala kuti "Arlette" malangizo Buku. Chithandizo (wodwala maganizo zimasonyeza) chida ichi chikhonza zoyambitsa zingapo zolakwika pa kapepala m'mimba mwa mawonekedwe a kusafuna kudya, nseru, kusanza, kutsekula m'mimba. Nthawi zina mungathe kumva za chiwindi anthu, koma osachepera - pa chitukuko cha matenda a chikasu ndiyo cholestatic, matenda a chiwindi, pseudomembranous matenda a m'matumbo.

Zimene chapakati mantha dongosolo kugwiritsa ntchito "Arlette" mankhwala kukhala kupweteka chizungulire, ofuntha (mu mawonekedwe a kusintha) ndipo ntchito kudwala.

dongosolo Hematopoietic angayankhe kuoneka zizindikiro leukopenia wa magazi m'thupi hemolytic, agranulocytosis. Mwina kuonjezera prothrombin nthawi (mu nkhani iyi, ndondomeko ndi kusintha). Crystalluria ndi interstitial nephritis - chomwe chingachitike ngati mankhwala kwa dongosolo mkodzo.

mndandanda mokwanira waukulu zotheka thupi lawo siligwirizana ndi mankhwala "Arlette". Malangizo, ikulongosola za mankhwala kudziŵitsa ogula za zotheka chitukuko cha pruritus, urticaria, erythematous totupa. Nthawi zina mungathe kumva za zizindikiro za exudative erythema multiforme, angioedema, anaphylactic mantha. Pali zambiri za maonekedwe munthu mavuto mu mawonekedwe a matenda Stevens-Johnson, ndi dermatitis exfoliative.

Contraindications ntchito "Arlette"

Mndandanda wa zifukwa zimene kuchepetsa kugwiritsa ntchito mankhwala kwa medicament ndi limapangidwa "Arlette" malangizo Buku. Contraindications kuchepetsa phwando kwa odwala amene akuvutika hypersensitivity munthu kwa Gawo ndipo wocheperapo wa mankhwala ena wothandizila beta-lactam antibacterial (penicillin, cephalosporins ndi zina zotero. P.). Sanagaŵiridwe "Arlette" ndi amene ali ndi mbiri ya ntchito kujambula la Nkhanza ku matenda a chiwindi amoxicillin ndi asidi clavulanic mu zovuta ndi. Mankhwala contraindicated anthu akuvutika mononucleosis ndi lymphocytic khansa, monga kumachititsa kukhala exanthema.

Malo chifukwa chokana mankhwala ndi mankhwala ndi aakulu aimpso kulephera ndi ana zaka 6.

Monga kwa amayi apakati, iwo akhoza kutenga "Arlette" kokha pamene ubwino kwa mayi indisputably kuposa ngozi anazindikira kuti mwana wosabadwayo. Pamene mkaka wa m'mawere ndi Gawo la mankhwala zochepa mu mkaka, kotero muyenera kukambirana ndi dokotala wanu funso chokana kuyamwitsa.

Mlingo Kugwiritsa

Matenda a m'mimba thirakiti - kuti ndi gulu lalikulu zizindikiro khalidwe la mankhwala ambiri osokoneza bongo, "Arlette" (piritsi). Malangizo ntchito, pamene umboni uperekedwa mtima anenapo kusanza, kutsekula m'mimba, kupweteka pamimba. Komanso, pangakhale mavuto monga kusoŵa tulo, ndi chizungulire, mukubwadamuka. N'kovuta kwambiri kumva za khunyu.

Pamene ambiri osokoneza zizindikiro za njira mulingo woyenera wodwalayo - kukhala kuyang'aniridwa ndi katswiri. Chithandizo motikomera symptomatic.

Ngati mfundo za kulandira unacceptably mkulu mlingo panalibe kuposa 4 maola zapitazo, m'pofunika kusambitsana kunja m'mimba ndi kutenga mankhwala, adsorbents (monga adamulowetsa makala) kuti kuchepetsa mayamwidwe. Jaji m'thupi la amoxicillin ndi asidi clavulanic othandiza hemodialysis.

Mogwirizana ndi zinthu zina ndi mankhwala

Mu chikuonetseratu kufanana "Arleta" ndi "methotrexate" zingawonjezere kawopsedwe wa masika. Kwambiri yafupika ndipo pang'onopang'ono mayamwidwe wa mankhwala Mankhwalawa ayenera kumwedwa, glucosamine, aminoglycosides. Ascorbic asidi M'malo mwake, kuwonjezera mayamwidwe - mfundo zimenezi zimaphatikizapo maantibayotiki "Arlette" malangizo Buku.

Mtengo wa mankhwala zimasiyanasiyana malinga ndi mlingo ndi dera, koma zilipo osiyanasiyana ogula. Choncho pamafunika kukaonana ndi dokotala, ndipo sakhala kuphatikiza kugwiritsa ntchito mankhwala ndi mankhwala ena.

"Arlette" moyandikana zotsatira coagulants chifukwa chopinga wa microflora matumbo, kuchepetsa kupanga vitamini K ndi kuchepetsa prothrombin index. Mu phwando zikufanana ndi mankhwala, anticoagulants n'kofunika mosalekeza kuwunika magawo a clotting magazi. Kuchepetsedwa mphamvu ya kulera m'kamwa.

NSAIDs, okodzetsa ndi kukonzekera zina zachipatala kupondereza katulutsidwe tubular, kuwonjezera ndende magazi a amoxicillin.

Mgwilizano "Arlette" ndi "Allopurinom" angachititse chitukuko cha exanthema. mankhwala bactericidal kuyambitsa synergism ndi mankhwala ndi njira bacteriostatic Chikoka - kwa chidani.

malangizo Special

Chifukwa chakuti mankhwala "Arlette" (malangizo Buku lili mfundo zimenezi) ndi mlingo wosiyana wa amoxycillin monga Komabe, yofanana asidi clavulanic (125 mg) ayenera adzanyamula kukumbukira kuti Magome awiri a 250 mg amoxicillin siife yokwana wina piritsi 500 mg wa thunthu.

Tiyeneranso adzanyamula kukumbukira kuti yambiri amoxicillin mwina hule onama ayankhe zabwino akamaona mlingo wa shuga mu mkodzo ngati ntchito kwa kusanthula zipangizo, monga Benedict wa reagent kapena njira yodula. Ndi bwino mu Zikatero ntchito zosiyanasiyana enzymatic ndi glucosidase.

Pa ntchito mitengo ya mankhwala zofunika zonse kuyan'ana mkhalidwe wa ntchito za magazi, chiwindi ndi impso. "Arlette" mu muyezo woyenera sikumangotikhudza luso kusamalira ndi kudzapereka ntchito njira zimene zimafuna chisamaliro ndi liwilo mosiyanasiyana psychomotor.

Price manambala ndi ogula maganizo mankhwala

Information pa Mlingo wa zotheka mwa zigawo zikuluzikulu mu mankhwala lili kuti "Arlette" (piritsi) malangizo ntchito. Price, monga tanenera poyamba, izo zimatengera pa mlingo ndi dera limene medicament ndi zinazake. Mwachitsanzo, filimu TACHIMATA miyala mu mlingo wa 875 mg wa + 125 mg mu Moscow zikhoza kugulidwa kwa ndalama mu osiyanasiyana kuchokera rubles 270 kwa 310 (zidutswa 14 pa paketi). Mu St. Petersburg phukusi yomweyo ndalama 278-282 rubles.

Pankhani maganizo a odwala za mankhwala mankhwala umene uli ndemanga zabwino ndi zoipa za mankhwala. A gulu lalikulu la anthu odwala zikusonyeza zotsatira kwambiri pa matenda a matenda a chapamwamba kupuma thirakiti thirakiti chapamwamba kupuma. Mankhwala mwamsanga ndi mogwira kupirira sinusitis, ndi chikhululukiro ndi motalika kokwanira ndiye. nchito zake mankhwalawa matenda bakiteriya amagwiritsidwa zikutsimikiziridwa ndi odwala review.

ndemanga zoipa za mankhwala mankhwala "Arlette" kuti nthawi zambiri chifukwa kukhalapo odwala hypersensitive kwa zigawo mankhwala. Zikatero, anthu kulankhula za zolakwika mu kugwira ntchito pa mundawo m'mimba, monga: kudzimbidwa, kunyansidwa ndi kusanza, kutsekula m'mimba. Za kuvutika iliyonse kwambiri pafupifupi palibe uthenga.

Komabe, kuyenera kuti ngati nthumwi antibacterial wasankhidwa ndi dokotala nawo komanso anatola mlingo mulingo woyenera, osiyanasiyana kupatuka mbali zimachitika kawirikawiri. Ngati chinachake chonga icho zinachitikadi, adokotala kusankha ofanana mu chikoka ndi dzuwa phindu analogi msika Russian mankhwala ladzala ndi mankhwala ndi sipekitiramu yotakata kanthu.