Matenda Addison n'chiyani?

matenda Addison akupezeka pamene wonongeka wa kotekisi adrenal. matenda anapezeka pa amuna ndi akazi, makamaka usinkhu wapakati (zaka 30 mpaka 40). Ndi matenda osowa, amene anawerengedwa mwa munthu mmodzi pa 100 zikwi. Population. matenda Addison Biermer ungapezeke chifukwa njira autoimmune, matenda opatsirana (chindoko, TB ndi adrenals typhoid), ndipo amyloidosis ndi zotupa zilonda. Mu 70% odwala matendawa amapezeka chifukwa cha zolakwa mu chitetezo cha m'thupi (chitetezo ayamba kutenga maselo a thupi, kwa matupi yachilendo, pomenyana ndi kuwononga iwo). Ndi kuwonongedwa kwa maselo adrenal kotekisi amachepetsa kaphatikizidwe gluco ndi mineralocorticoids (tochepa, 11 deoxycorticosterone, aldosterone). Asayansi asonyeza kuti glucocorticoids malangizo osiyanasiyana njira amuzolengedwa mu thupi (nthawi magazi, insulin ndende, zochitika pa lamulo la mapuloteni kaphatikizidwe, lipids ndi chakudya).

Gipokortitsizm zambiri anamuona pa odwala kuchizidwa ndi mahomoni wa kotekisi adrenal. Nthawi zambiri, etiology matendawa Zatsala osadziwika. Adrenal insufficiency zimagawidwa m'magulu pulayimale ndi sekondale. kulephera chachikulu akufotokozera mu kugonjetsedwa kwa minofu adrenal, ndi sekondale - chifukwa osakwanira kukondoweza kwa timadzi adrenocorticotropic.

Addison Nthenda Zizindikiro

zizindikiro matenda a matenda chifukwa cha kuperewera pa chamoyo mchere ndi glucocorticoids. Mbali kwambiri khalidwe ndi kufooka, hypotension, osokonekera m'mimba (nseru, kusowa chilakolako kusanza, kudzimbidwa, m'mimba nthawi zambiri m'malo). Odwala ena hypochlorhydria.

matenda Addison kukuchitikira pamodzi ndi kuchuluka irritability kapena maganizo maganizo, mutu pafupipafupi ndi tulo. X-ray a chifuwa limasonyeza kuchepa kukula mtima. The electrocardiogram nkhani zizindikiro za hyperkalemia (mkulu ndende potaziyamu m'magazi). Khungu mtundu susonyeza zovuta matenda Komabe, choonjezera kapena kuchepa mu mankhwala a umboni pa mphamvu ya kanthu achire.

matenda Addison a amakhala ndi chiyambi cha zizindikiro za sekondale zochepa kwambiri. Kwambiri kawirikawiri matenda kumaonekera popanda mtundu (kotero mutu wa "woyera Addison"). Chifukwa chachikulu cha matenda ndi TB adrenals. Popeza chithandizo choyenera matenda Addison ndizovuta. zizindikiro matenda ali nakweza: nseru, kusanza, kutsekula m'mimba, kuthamanga kwa magazi akutsikira zikuchepa, kuwonjezera ndende ya potaziyamu m'magazi. Mu magazi zotumphukira wa Nayitirojeni yotsalira kumawonjezera chiwerengero maselo a magazi, magazi. Choncho, ngati m'nthawi ya mavuto addisonicheskogo mtima sasamalira thandizo yake, iye afa ndi zizindikiro za aimpso ndi matenda a mtima.

Magawo zofunika kwambiri zasayansi kwa matenda ndi ochititsa 17 OCS mu madzi ndi 17 KS mu mkodzo, komanso kuchepa madzi a shuga magazi. Morphological Kupenda magazi limasonyeza lymphocytosis, eosinophilia ndi ESR anachedwa.

matenda Addison ali kusiyanitsidwa ndi matenda otsatirawa: shuga mkuwa, pellagra, poizoni arsenite ndi Bismut Argentum. Matendawa zambiri ali Inde aakulu ndi peaking nthawi. matenda Addison Biermer kusalekerera anatsimikiza ndi zovuta zizindikiro zazikulu za matenda, komanso ndi nambala ya mankhwala ofunika zoperewerazo insufficiency adrenal.