"Engerix" - katemera chiwindi B zikuchokera katemera, analogs ndi ndemanga

"Engerix" - katemera osiyana ndi chitukuko za matenda B. Chifukwa cha ntchito zake umabala chitetezo chokwanira kwa causative wothandizila matendawa. Katemera - HIV Antigen (chachikulu padziko), otsiriza kuyeretsa ndondomeko, adsorbed pa hydroxide zotayidwa. Katemera umatulutsa zophatikizananso kukhazikitsa DNA luso.

The efficacy wa mankhwala pamene kutumikiridwa achikulire, ana ndi makanda omwe ali pachiopsezo, pafupifupi 98%. Akuluakulu a katemera popangidwa ndi oteteza HBs pokha, zomwe ndiotetezedwa motsutsana a chiwindi B. coinfection "Engerix" chingalepheretse chiwindi D.

The zikuchokera, amasulidwe mawonekedwe "Engerix" mankhwala

njira zikupezeka makapisozi. Mlingo zimene tikubweretsazi mwana limafanana ndi 0.5 ml munthu wamkulu - 1 ml. CD lili ku Mbale zana (khumi kapena zana ndi makumi asanu).

"Engerix" sewerolo komanso umathandiza Mbale kuti akupanga 5 ml (lolingana ana 10 Mlingo) ndi 10 ml (lolingana Mlingo 10 akuluakulu) katemera. mapaketi ndi mabotolo makumi asanu a "Engerix".

The mankhwala ndi akuluakulu

The zikuchokera katemera 1 ml zikuphatikizapo tizilomboto Antigen (20 micrograms) ali m'gulu hydroxide zotayidwa. The ntchito usawonongeke chiphunzitso ndi dzina "2-Phenoxyethanol", pali kuda thimerosal, kuyambira ntchito mankhwala opanga medicament. Iwo kuthetsa thimerosal kuchokera katemera, pamene kuyeretsa ikuchitika. Mu kupanga mankhwala ntchito ndi sodium wochuluka digidrofosfatadigidrat gidrofosfatadigidrat, madzi wosabala anawonjezera.

A katemera wa ana

Kuti 1 ml ya kukonzekera "Engerix" katemera zikuchokera motere:

• tizilomboto Antigen (10 micrograms);
• osachepera kuchuluka kwa mankhwala thimerosal;
• zigawo zina (mofanana mu yokonza munthu wamkulu).

zotsatira pharmacological

Antigen The amapangidwa kudzera yisiti Saccharomyces chikhalidwe, ali ndi chikoka ena. Yopangidwa Saccharomyces kuchotsa maselo ku Antigen, ndondomeko izo mokwanira kuyeretsedwa waudindo wake. Pali deta kusonyeza luso la "Engerix" kuchepetsa mosavuta osauka carcinoma hepatocellular chifukwa akuluakulu a katemera kwa tiana.

Zikuonetsa ntchito

"Engerix" malangizo ntchito akulimbikitsidwa kupewa matenda a chiwindi B, amene amayamba ndi kwa mawu HIV. Katemera tikulimbikitsidwa magulu pangozi. Pamafunikanso:

• anamwino;
• anthu amene adzakhale kudzera kuziika ziwalo;
• okhala m'madera kuderako kwa chiwindi B;
• anthu akuvutika uchidakwa;
• zachipatala ophunzira;
• odwala amene ali okonzeka kuchita ntchito kapena olanda njira yodziwira;
• onyamula HIV kamene kamayambitsa chitukuko za matenda C;
• ogwira ntchito amene kubala kukonzekera immunobiological munali zigawo magazi;
• ana amasiye, sukulu yogonera komweko;
• ogwira ntchito choyezera, akuyendayenda zakuthupi anthu;
• Odwala amene ankachitira kutsatira jekeseni mankhwala;
• anthu akuvutika aakulu chiwindi C mawonekedwe;
• Ana obadwa kwa amayi omwe ali ndi nthumwi causative a chiwindi B;
• anthu amene amadziŵika chikwakwa-selo magazi m'thupi ;
• anthu amene anakumana ndi anthu amene anatulukira chiwindi B mtundu uliwonse;
• Anthu pa chiopsezo kuchepa chiwindi B ufulu kugonana;
• Anthu amene akonza apite kuchigawo kuderako kwa chiwindi B;
• anthu akuvutika ndi matenda aakulu chiwindi akulowera;
• odwala akufunika magazi, zipangizo mwiniwake opangidwa kuchokera ku magazi.

Katemera motsutsana a chiwindi "Engerix" angathe kuchitidwa pa msinkhu uliwonse. Linapangidwa amene sanalandire katemera kale, ndipo anthu a gulu chiopsezo.

contraindications

katemera si kutumikiridwa mu hypersensitivity omwe wapezeka pambuyo jekeseni mankhwala m'mbuyomu. Pamaso pa matenda ndi pachimake zilikuchitika, akuluakulu njira opatsirana mmene muli kutentha thupi, - contra-zikuonetsa katemera.

Ngakhale kuti umboni wa kuwonongeka katemera mwana wosabadwayo, kwina pa akazi wobereka kawirikawiri katemera. kukhazikitsa kawiri kawiri zimachitika pokha pokha wapadera komwe pali zizindikiro.

Ntchito ya katemera, mlingo

Dongosolo mu mnofu ndi kuchita mu anterolateral ntchafu gawo (ana ang'ono, makanda) mu mnofu deltoid. Mwina makonzedwe subcutaneous, koma ikuchitika nthawi zina, pokhapokha ngati wodwala anakantha dongosolo magazi coagulation. Ankalumikiza "Engerix" sanachite m'nsinga. Chifukwa cha Mwina otsika Poyankha m'thupi kukusalani intradermal, subcutaneous ndi mu mnofu jekeseni ku thako lapansi.

Mphamvu ya katemera asanalankhule jekeseni bwino kugwedezeka mpaka slurry yochitidwa ndi wogawana kugawa. lokonzekera sayenera particles yachilendo. Nthawi kumene mawonekedwe a katemera si zizigwirizana ndi kufotokoza, zikutanthauza kuti uwu si ntchito katemera.

Ngati "Engerix" (katemera) ntchito vial, mu adani a mlingo uliwonse m'pofunika kutenga singano wosabala ndi syringe. botolo anayamba angagwiritsidwe ntchito kuti munthu pazipita kumapeto kwa tsiku. Zimenezi zimafuna kugwilizana ndi muyezo anapereka malamulo a antisepsis, asepsis.

mlingo

Katemera katemera chiwembu anatsimikiza, amene analandira dziko. N'zimene njira zopangidwa mogwirizana ndi msinkhu:

• kwa zaka 19 - 0.5 ml ya;
• zaka 19 - 1 ml;
• mankhwalawa odwala amene ali unit hemodialysis, - 2 ml.

vaccinations ubwana zodzitetezera

Mwana katemera kuchita atabadwa, mwezi umodzi ndi isanu. Pamene ndikukhazikitsa chiwembu kale mu mwezi wachisanu ndi chiwiri wa moyo m'thupi wa mwana tizilomboto za matenda B. Ngati pali kufunika imathandizira ndondomeko imeneyi, jekeseni lotsatira imagwiridwa atabadwa mwezi woyamba wa moyo, ndiyeno - wachiwiri. Pa mwezi akhumi wa kukhazikitsa revaccination chofunika.

Ngati munthu wamkulu ana sanalandire katemera pambuyo mlingo woyamba wa nkhani lachiwiri pa tsiku lachisanu ndi chiwiri, wachitatu - mu makumi awiri oyamba. chaka chimodzi pambuyo ntchito yoyamba ya mankhwala chikuyendetsedwera mobwerezabwereza katemera.

Pamene hemodialysis ndondomeko chiwindi B katemera 'Engerix "anayambitsa pansi chiwembu kuti: Tsiku ziro - mmasate - zaka zao za sikisite. Mobwerezabwereza ntchito mankhwala pasanathe miyezi sikisi pambuyo utsogoleli choyamba. Odwala zomwe zimapanga gulu zimenezi, jakisoni ndi mlingo awiri (2 mg). Pambuyo utsogoleli wa mankhwala tikulimbikitsidwa kuchita mayeso serological (mlingo wabwinobwino ayenera kukhala osachepera 10 IU / l).

Makanda ndi mavuto aakulu impso wovulala 0.5 ml ya mankhwala, aliyense oyenera kutsatira madera vaccinations. Mlingo wofanana wa mankhwala chofunika makanda amene amachita hemodialysis.

Munthu amene akhudzidwa ndi zinthu chifukwa cha zomwe ungachitike matenda, ntchito ndi inapita patsogolo katemera ndandanda. Mlingo woyamba pamodzi ndi mankhwala, a chomwe immunoglobulin ndi. wothandizila oterowo zoyipa pa chiwindi B. jekeseni mankhwala Buku "Engerix" malangizo akuonetsa kuti kuchita popanda jekeseni wa immunoglobulin (m'malo osiyanasiyana).

Ngati mukufuna katemera akhanda amene mayi - chotengera cha tizilomboto kapena matenda matenda a chiwindi B, kuyambira mwezi wa chisanu ndi pakati, atabadwa katemera wovulala kwa iye mu zoyambirira za tsiku. Katemera Komanso ikuchitika mwa njila expeditious. Nthawizina, mu Zikatero Ndi bwino kugwiritsa ntchito katemera kuti zamoyo immunoglobulin.

Atayendetsa munthu chiwembu lonse la katemera motsutsana a chiwindi B revaccination Sikuti. Pambuyo dialysis ndi osauka ayankhe m'thupi angathe kuperekedwa ndi chilimbikitso mlingo. Kufunika kukhazikitsa kumatanthauza mayeso serological.

Zotsatira zoyipa "Engerix"

Taganizirani zimene zoipa za thupi, chitukuko cha zimenezi zingachititse katemera 'Engerix ". The malangizo kufotokoza zotsatira ngati mbali, amene akhudzidwa minofu ndi mafupa ndi m'mimba kachitidwe. Pangakhale monyanyira mu ntchito kwa dongosolo zotumphukira mantha, mtima, n'zotheka kusintha chapakati mantha dongosolo. Pambuyo jekeseni, zikhoza kuonedwa ndi ena m'dera lawo siligwirizana anachita.

Thupi la munthu angayankhe mawonetseredwe katemera zizindikiro fuluwenza ngati, malaise, malungo, ndi imfa ya mphamvu. Nthawi zina, kukhala thrombocytopenia, lymphadenopathy limapezeka bronchoconstriction. Childs, kukwiya kwa katemera wofatsa.

Nthawi cha mankhwala osokoneza bongo a katemera ndiribe chavumbulutsidwa. Kodi kuchita zinthu zoterezi mu chitukuko cha zizindikiro osafunika sizinafotokozedwe malangizo.

Isanafike ntchito, bwinobwino mwachidule ndi dokotala.

Mwanjira mankhwala

"Engerix" (katemera) pamene ntchito immunoglobulins pamene kuteteza chiwindi B, sizichepetsa ndi titer a chitetezo malinga ndi utsogoleli wa mankhwala amachitidwa payokha mu mfundo zosiyanasiyana. Apo ayi, chizindikiro sadzakhala mu osiyanasiyana yachibadwa.

Mukhoza kugwiritsa ntchito katemera kuti kumathandiza chitukuko cha matenda a chiwindi B, pamodzi ndi zipangizo zina za mtundu uwu, amene atchuka mu kalendala ya Katemera ndi katemera ngati njira muyeso zizindikiro mliri. Nkofunika kuti katemera awiri osiyana ndi kutumikiridwa mu syringes osiyana pa mfundo ziwiri zosiyana.

Ankalumikiza "Engerix" zikhoza kukhala chomaliza m'ndime a chiwindi B katemera milandu pamene anayamba ntchito katemera wina kuti ndi cholinga chofanana. M'mikhalidwe yemweyo, "Engerix" angagwiritsidwe ntchito pa revaccination.

zochita Kulanga kwa chamoyo ndi katemera kuwaphatikiza ndi mankhwala osiyanasiyana akhala anati.

Kusamala

pa mimba

Theoretically, Mwina kuvulaza mwana wosabadwayo ndi kochepa chifukwa oyamba a katemera. Chipatala maphunziro, zomwe ikomze zotsatira za "Engerix" pa thupi, kuphatikizapo pa mimba sizinachitike anachita. "Engerix B" (ofanana ndi omwewo) ndi wofunika jekeseni akazi woyembekezera, koma ndi umboni yoyenera anakhazikitsa dokotala.

Features mankhwala

Nthawi makulitsidwe kwa chiwindi B amakhala ndi mfundo kuti kumatenga kwambiri, choncho pali kuthekera matenda zobisika za otaya pa nthawi ya katemera. Odwala awa, kupewa matenda a chiwindi B ndi zosatheka.

Chifukwa katemera sangalepheretse yatsoka matenda, kupanga Zimenezi zimathandiza kuti tizilombo toyambitsa matenda ena. Mwachitsanzo, mankhwala ndi operewera ngati n'koyenera kupewa chitukuko cha matenda a chiwindi A, C ndipo E. Iwo komanso alibe zotsatira anakhumba pa toyambitsa matenda ena amene chiwindi zimakhudzira.

"Engerix" (katemera) pambuyo oyamba mu thupi amachititsa yankho m'thupi, mawu ake amadalira zifukwa zambiri. Mwachitsanzo, yankho m'thupi a dongosolo anatsimikiza ndi kugonana kwa munthu, msinkhu wake, pamaso pa makhalidwe oipa monga kusuta fodya, njira imene katemera polima. Nthawi zambiri, zitatha zaka makumi anayi, ndi chitetezo cha m'thupi ayankhe sichidziwika kutchulidwa kuposa achinyamata. odwala amenewa amathera vaccinations zina zoyenera.

Ngati wodwala ali ndi kachirombo ka HIV, mavuto ena m'thupi ndipo chifukwa cha dialysis sangathe kukwaniritsa chokwanira oteteza titer. Ngati njira yaikulu sadzalola kulowa kwa anthu a mtima, malinga ndi zotsatira za kuwunika kungafune jakisoni zina. Chifukwa luso chifukwa zochita anaphylactic, amene losiyana katemera mayankho 'Engerix' inanena za kufunika kokhala ndi zipangizo zapadera kuti kuthetsa zotsatira za mtundu uwu, pamene utsogoleli wa mankhwala. Chifuwa akhoza kuoneka mofulumira kwambiri, kotero muyenera kukhala kwa mphindi makumi atatu kuti azisunga mmene wodwalayo amene jekeseni anapangidwa.

Pamaso pa matenda zazing'ono katemera chamoyo imatheka pamene kutentha thupi akubwerera mwakale. The mfundo umene ankafuna kuti atchule katemera, ayenera kusonyezedwa wothandizila anafuna mankhwala odana ndi mantha.

Katemerayu angagwiritsidwe ntchito ngati mavuto mu chiwindi chake mosamala kutumikiridwa kwa anthu okalamba.

analogues mankhwala

Kupewa matenda a chiwindi B n'zotheka kusankha katemera 'Engerix "kapena" Regevak ". Analogs a "Engerix 'zipangizo zotsatirazi otchuka:" Euvaks "," Biovak ". Mwina katemera "Eberbiovakom HB", "Shanvakom", "HB-Vaks." Oyenera mankhwala anasankha dokotala.

Ndemanga za "Engerix" njira

Ngati ndi kotheka, kupanga katemera chizolowezi ndi katemera chiwindi B zambiri "Engerix" limagwirira ntchito. Makolo osaganizira zotsatira iliyonse mbali, iwo zambiri wokhutitsidwa ndi zotsatira zake. Panopa, pali zambiri maganizo abwino okhudza mankhwala.

"Euvaks" umakopa kwambiri chida, koma makolo kumva si monga mogwira mtima "Engerix". Reviews zimasonyeza kuti Baibulo lachiwiri la katemera zambiri analimbikitsa ndi madokotala.

Kukonza sakhala ndi mavairasi, alibe tizilombo kuphedwa, kuli moyo. Katemera maziko - Antigen anapanga ndi yisiti chikhalidwe choyera.

Kuchita katemera aliyense kungachititse pang'ono kuwonongeka zosakhalitsa thanzi, koma chiwindi B «Engerix" Nthawi zambiri otetezedwa bwino. M'chigawo yachibadwa ya chitetezo cha m'thupi ndi nthawi kufunika ayankhe m'thupi alipo.

Osati aliyense akufuna kuti katemera, koma tiyenera kumvetsetsa popanda inu muyenda angathe kutenga matenda ambiri oopsa. Pamene katemera mankhwala "Engerix 'Katswiri amaganizira ambiri zinthu zosiyanasiyana kumatha kuvulaza thanzi. Pafupifupi onse milandu, chifukwa cha ntchito yake ya katemera sindikufuna kukhala matenda.

Khalani wathanzi!