Cachexia - ndichiyani? Cachexia khansa

Cachexia - ndichiyani? Cachexia, mwa kulankhula kwina, zikutha m'mayiko thupi - ndondomeko zovuta yodziwika ndi imfa chidwi thupi ndi zofooka ambiri komanso kusintha malingaliro. Izi kwambiri zatha mafuta ndi zimam'patsa nkhokwe, yafupika mapuloteni kaphatikizidwe, pamene kuwonjezeka catabolism ake (kusokonezeka). Cachexia akhoza zimachitika matenda oncological.

Pulayimale ndi sekondale kutopa

mitundu iwiri ya matenda cachexia - pulayimale ndi sekondale. wakuta chachikulu umatchedwanso pituitary, ndi sekondale - symptomatic.

● cachexia pulaimale kapena exogenous kumachitika chifukwa wambiri osakwanira zakudya, komanso chifukwa cha matenda otsatirawa: zoopsa oziziritsa, chotupa kapena zokhudza zonse chotupa pituitary, autoimmune hypophysitis, kuvutika maganizo kwakukulu, kukha mwazi (magazi pa zotengera kupatulira), anorexia, embolism ( ingress wa particles zakunja panopa magazi, kuchititsa mtima occlusion), aakulu matenda enieni.

● Secondary kapena amkati cachexia chifukwa cha matenda ndi chimapangidwa ndi zinthu monga gipoinsulinizm (akusowa insulin), kuchulukitsidwa kaphatikizidwe glucagon, malabsorption (malabsorption zakudya), akusowa glucocorticoid, kukula neoplastic, owonjezera somatostatin.

zimayambitsa

matenda Cachexia kumachitika chifukwa cha zifukwa zingapo ndi zinthu:
1. yaitali kutupikana ndi njala.
2. Matenda pa mundawo m'mimba, makamaka kum'mero, komanso matenda celiac, enterocolitis.
3. yaitali kuledzera ndi brucellosis, TB ndi matenda ena opatsirana ndi njira aakulu suppuration.
4. Psychogenic matenda a anorexia.
5. Matenda a chithokomiro England, adrenal insufficiency.
6. matenda Endocrine kugwirizana ndi matenda kagayidwe kachakudya.
7. Mtima kulephera.
8. Yapakhungu chotupa.
9. Mosataya ana.

Kodi zizindikiro za cachexia amakhala ndi? ndi zizindikiro zotani?

symptomatology

Pali zizindikiro, amene amakhala ndi cachexia. Kuti matenda amachita kwa matupi athu:
1. mwadzidzidzi kuwonda la 50% ya kulemera kwa thupi, ndi Zikavuta kwambiri kuposa 50%.
2. Kuperewera kwa madzi m'thupi.
3. Minofu kuchepa mphamvu.
4. kulemala.
5. Tulo matenda.
6. Awonjezere kugonjetsedwa ndi matenda.
7. Idzayambitsa magazi (wolumikizira kuthamanga).
8. wofooka ndi flabby khungu.
9. Kodi vitamini akusowa, ndi imfa dzino.
10. kusintha Trophic mu tsitsi ndi misomali.
11. Kukula kwa stomatitis.
12. Nthawi ya kudzimbidwa chifukwa matenda m'mimba motility.
13. otsika mapuloteni okhutira wa magazi, albumin, chitsulo, B12.
14. Akazi kumachitika amenorrhea (kutha kwa msambo).
15. matenda Mental.

Cachexia ndi psyche

Ndikufuna kulunjika pa matenda maganizo cachexia. Iwo akhoza kuonekera irritability, maganizo ndi tearfulness kuti bwino kuyenda mu mphwayi, kusokonezeka wathunthu. Pa exacerbation la matenda amene anali kuchititsa cachexia zingaoneke amentia / amential syndrome (chizungulire, yodziwika ndi kulephera ndi kuganizira, wachisokonezo kuyenda ndi chododometsa, ndi incoherence wa maganizo ndi malankhulidwe) kapena kuona zilubwelubwe (misala imene munthu ali mu mkhalidwe zonse nkhawa ndi chisangalalo amaona kuyerekezera zinthu m'maganizo), psevdoparalich.

Cachexia ku Oncology

Khansa cachexia - ndi matenda amene mosalekeza amachepetsa chigoba minofu misa ndi minofu adipose mu chitukuko cha formations chotupa payekhapayekha chakudya. Wakuta makamaka kutchulidwa odwala amene ali ndi khansa ya m'mimba thirakiti kapena mapapo ziwalo. Anthu amenewa akhoza kutaya kwambiri monga 80% ya kulemera kwa thupi, zikubweretsa kulephera kuyenda.

Cancer monga chifukwa cha cachexia

Cachexia khansa zotheka. Chifukwa cha cachexia kungakhale chotupa. Chifukwa cha zotupa kagayidwe amakhala atypical, kusintha kwa izo. Chotupa ayenera magawo, okhoza kuonetsetsa kukula ndi chitukuko. Si chinsinsi kuti khansa cachexia zoledzeretsa zimakhudzanso zimakhala wathanzi ndi ziwalo, bongo dongosolo lawo ndi kuchititsa malfunctions.

Mu mapangidwe zotupa mu wambirimbiri asidi lactic ndi zowonongeka chiwindi. Pofuna kuteteza matenda a ndende asidi lactic, thupi limayamba kugwiritsa ntchito magazi shuga, ndi zambiri osati amapanga zochokera.

Pamene khansa cachexia anati:
- kuchepa zoopsa kulemera ndi zofooka;
- kuphwanya njira kudziletsa lamulo;
- kuchepetsa plasma mafuta m'thupi;
- chitukuko cha matenda chifukwa kuphwanya chitetezo chokwanira ma ndi humoral;
- dysphagia (movutikira Pomeza);
- kusanza, kutsekula m'mimba;
- kuwonjezeka mu ankafuna mphamvu;
- antidiuresis ndipo, chotero, hyponatremia;
- hypercalcemia;
- kutupa;
- kuwonjezeka glucocorticoids magazi;
- zina, kuona zilubwelubwe ndiponso chikomokere.

Zotsatira za khansa cachexia

Cancer cachexia ndi choopsa kwambiri. Kuchuluka magazi glucocorticoid imayendetsa njira gluconeogenesis (shuga kaphatikizidwe) mu chiwindi ndi minofu minofu, kumaonjezera kuwonongedwa kwa mapuloteni ndi mafuta. Chifukwa shuga kutengedwa ndi maselo a khansa akufotokozera hypoglycemia (otsika magazi shuga). Pa maziko awa (amene mwina zidzawonjezedwa kwa nkhawa), endocrine zopangitsa mwachangu kutulutsa mahomoni kuchuluka owonjezera imbaenda kuledzera ndi hemic hypoxia (yafupika kusiyana arteriovenous mpweya masinthidwe amtundu). kuvutika Homeostatic zimachitika. Zonsezi zingachititse kuti imfa.

cachexia chithandizo

Ambiri mwa mankhwalawa odwala cachexia anachita m'zipatala kapena zipatala. Mankhwalawa waukulu zikuphatikizapo amalimbikitsa kutaya neoplasms. Mawaya ndi kuchira mphamvu zimatheka ndi zawachitikira thupi ndi mavitamini, kufufuza zinthu, mafuta ndi mapuloteni. Chifukwa chaichi angagwiritsidwe ntchito zakudya mosavuta zidyeke. Ntchito mankhwala: a multivitamin zochizira hypovitaminosis, michere kusintha chimbudzi. Chakudya umayamba m'njira ziwiri: enteral (pamene akulowa m'mimba thirakiti) ndi parenteral (chakudya angamachite thirakiti m'mimba). Parenteral agwiritsa ntchito njira kuchotsa wodwalayo boma molimba (chikomokere) pa matenda a khansa ndipo, kwambiri zakudya m'thupi, matenda akulu pambuyo pawo, Pomeza matenda. Choncho kutumikiridwa shuga, mavitamini, amino asidi zosakaniza, electrolytes, hydrolysates mapuloteni (kutumikiridwa parenterally). Komanso, kuchita ntchito zida kuti kuonjezera kudya. Ngati wodwala akudwala mkhutu chimbudzi chakudya ndi mayamwidwe ake, ntchito mankhwalawa mankhwala polyenzyme (mankhwala "Pancreatin", "zoikidwa" mankhwala).
Pofuna kupewa kusanza, mankhwala njira "Delta-9-tetrahydrocannabinol". Ndi bwino ndipo pambuyo mankhwala amphamvu. Cannabinoids ali kukonzekera imeneyi, chilakolako, ndipo motero, ndipo kunenepa. kuwonda akhoza anasiya ntchito mafuta nsomba, kotero izo ndi gawo la mankhwala a matenda, monga cachexia.

Chithandizo ndi mankhwala.
Kuthetsa ntchito cachexia mankhwala:
1) "carboxylase" - amathandiza matenda kulemera, kuchepetsa ululu ndi kuthandiza kachitidwe thupi. Zotsatira zoyipa za mankhwalawa - matupi awo sagwirizana. Izo sizingakhoze ntchito, ngati chamoyo ndi atengeke chigawo chimodzi.
2) "Megeys" kapena "megestrol nthochi" - amafalitsa kuwonjezeka minofu misa ndi mafuta. Izo sizingakhoze ntchito ngati pali kudziwa zigawo zikuluzikulu za mankhwala, kwa anthu pansi zaka 18, pa mimba ndi yoyamwitsa.
Mu kukhalapo kwa matenda opatsirana monga mankhwala mankhwala antibacterial. Ngati ndi kotheka, kulowa anaboliticheskie mahomoni. Nthawi matenda psychogenic nawo mankhwala a zamaganizo a.
Tikukhulupirira ife anayankha funso lanu "Cachexia - chimene icho chiri, mmene kumasulila ndi mmene nkhondo."