Anti-TPO - mayeso tcheru kuti matenda a thyroiditis autoimmune

Pamodzi ndi matenda a dongosolo mtima m'kati kukula ndi endocrine matenda - shuga ndi chithokomiro zotupa zamitundu yosiyanasiyana.

Mbadwo Wotsirizira ali ndi wapadera malo hypothyroidism, kuyambira chikuoneka ana amachititsa kupanda choopsa cha maganizo ndi thupi kukula kwa mwanayo. Nthawi zambiri, otchedwa autoimmune thyroiditis kapena Hashimoto a. Mu matenda angayambe m'njira zitatu matenda. hypertrophic ili, limene compensatory hyperplasia ya chithokomiro England, atrophic, kukhala gawo lachiwiri la matenda ndi amakhala ndi m'malo a yachibadwa connective dongosolo minofu, ndi alopecia limene chotupa chimakwirira chimodzi chokha gawo thupi.

kusanthula kufunika

Nthawi zambiri okha umboni molondola matenda ndi magazi kudziwika odana TPO, i.e. akupha chithokomiro peroxidase - pulayimale enzyme mapangidwe triiodothyronine ndi thyroxine.

Chifukwa cha ntchito yawo akusokoneza iodination wa thyroglobulin, chithokomiro structural mapuloteni kuti midadada zina kaphatikizidwe magawo mahomoni ake. Popeza ndi mayeso tcheru kwambiri matenda a khosi lotupa Hashimoto, ndiye dotolo amaganiziridwa ndi matenda ulipo ndi mahomoni magazi mayeso. Anti-TPO mu nkhani ya zabwino udzakhala wautali, kenako matenda kwathunthu anatsimikizira. Only mu nkhani iyi, dokotala ali ndi ufulu kukhala ndi khalidwe chithandizo choyenera ndi kupereka madokotala ananena zawo zabwino wodwalayo. Makamaka kwambiri ndi mayeso kwa amayi apakati, T. Kwa., Ngati iwo kusonyeza odana TPO, akulankhula za chiopsezo kwambiri kukhala postpartum thyroiditis ndi zoipa chikoka cha matenda pa mwana wosabadwayo. Mlingo wa chitetezo awa atakhala 0-5,6 IU pa milliliter wa seramu, ndipo kuchepa zingaoneke anthu athanzi pansi ndi zaka 50. Koma zabwino (wotsutsa-TPO pamwamba yachibadwa) chiyeso kukhala matenda ena a chithokomiro England, kotero matenda a pathologies izi zichitike kwenikweni zovuta, pamodzi ndi kusanthula ndi pa T3, T4 ndi TSH.

kafukufuku zovuta

matenda Hashimoto a kumachitika pamene walephera chitetezo cha m'thupi, ndiko kuti, pamene amamvetsera kwambiri kapena kuchepetsa T-suppressor ntchito. Choncho (pamodzi ndi odana TPO) mu magazi odwala zimapezeka chitetezo ena: kapangidwe monga chithokomiro (thyroglobulin microsomal kachigawo) ndi ziwalo zina kwathunthu. Izi zimapangitsa kusakaniza ndi zina, osati endocrine, pathologies chiyambi autoimmune. Kuwonjezera kuyezetsa kwa odana TPO timadzi, zofunika chida chitsimikiziro khosi lotupa Hashimoto. Choncho, pa ultrasound mosamala chithokomiro England angasonyeze heterogeneity wa matabwa ake, hypoechogenicity ena zigawo, pamaso pa calcification ndi thickening ya kapisozi pa. madokotala ananena zawo More aakulu akukhala milandu kumene limba adzakhala mfundo ngati za 5% milandu iwo ozlokachestvlyayutsya.