Wosaoneka mwachizolowezi diso Blashko mzere pa thupi la munthu

Imperceptible chito maliseche diso pa thupi la munthu zimachitika mchikakamizo cha zinthu amkati ndi exogenous negative. Tsimikizani ndi kudwala ngati mizere Blashko. Melanogenesis akuwonetseredwa hypopigmentation, chikukhudza gulu la matenda dermatoses. Looneka chosaopsa chidwi ndi sayansi. Kumvetsa mfundo za maonekedwe a chotupa cha n'zotheka kuteteza maonekedwe a khansa.

Mbiri ya kuphunzira matenda pakhungu

German kafukufuku mavuto dermatological anapeza Blashko mzere mu 1901. Iwo akuyimira chitsanzo cha mtundu, ofanana mu dongosolo odwala onse. Matendawa unatchedwa dzina la wasayansi, amene dzina lake ndi Alfred.

Dermatologist anakhazikitsa ubale ndi zosayembekezereka wa kudwala X-DNA. Pa khungu labwino kusintha imperceptible mu ndende zawo. Chifukwa cha kusamuka wachisokonezo malanoblastov mapangidwe zooneka dera chitsanzo. Momwe maselo mutated amadalira kuwonongeka mantha thupi. Komabe, mavuto dermatological angapezeke mu kobadwa nako cholowa cha matenda.

zifukwa zazikulu zolakwika wa khungu anthu

Kudziwa zinthu zotsatirazi Education Blashko mzere pa thupi:

• Chimerism - zambiri amatchedwa chikhalidwe munthu akungoyang'ana mitundu iwiri ya DNA. A zosiyana majini akapsa mapangidwe mtundu m'thupi. Zimenezi awulule pachibale ndi mitundu iwiri yosiyana. Zimayambitsa khungu kudwala amakhala maphatikizidwe wa dzira pa siteji oyambirira mimba.
• Human nkhawa vutoli - chitsanzo wachisokonezo aumbike.
• Chibadwa - kusintha mu DNA anthu. Chifukwa kuoneka kudwala kobadwa nako amakhala nevi: depigmented, inki, sebaceous, liniya verrucous yotupa.
• Majini kusanganikirana DNA pa embryogenesis - asayansi wokwera Kapangidwe ka zimakhala anthu: mu umodzi khola ya chibadwa zimawonedwa. Ngakhale chiyambi cha iwowa lachokera ku zygote limodzi.

Chikhalidwe cha maonekedwe a dermatosis

N'zokhumudwitsa kuti ndisadziwe mawu akuti "Blashko mzere" - chimenecho ndi mzere? mavuto amenewa amapezeka makanda, mosachuluka kuposa 2% amene ali predisposed kuti maonekedwe a pathologies. Kapangidwe ka DNA ndi poyamba muli matenda zambiri. zizindikiro kunja uka chifukwa cha zolakwika Endocrinology thupi.

Blashko mzere yodziwika ndi maselo atatu mu thupi, ndi gwero la matenda:

• Epidermal keratinocytes - anapeza kudwala zambiri anati chifukwa cha chimerism.
• Inki - ili mu zigawo za mmusi za khungu.
• Profiling malire maselo pigment - kumabweretsa kusintha khungu, kudutsa chapansi Kakhungu mu pamwamba wosanjikiza wa dermis lapansi. boma zimawonedwa pa titadziwa chikhalidwe cha mapangidwe khansa.

zizindikiro zakunja

mabuku zachipatala zambiri za mizere Blashko: kuti ndi matenda a zimakhala anthu, amene kumaonekera mu nkhani ya zolephera mu thupi kwa moyo. Kapangidwe chitsanzo yosaoneka pa gawo kumbuyo akufanana mtundu wa nyama mbidzi kapena kambuku. Iwo Tingaone ndi cheza ultraviolet.

Mtundu wa khungu anthu zimadalira mankhwala a pigment melanin. Iwo aumbike mwa khungu zimakhala, woyambira wosanjikiza limapangidwa melanocytes. Zolakwika mu ndondomeko ya melanogenesis kumabweretsa kusintha mtundu zowoneka amaonekera:

• Hyperpigmentation - chitsanzo wachisokonezo mawanga mdima pa khungu, bwino siyanitsa ndi zofunika mthunzi chimakwirira.
• Hypopigmentation - imfa ya mtundu wa khungu, chifukwa mawanga yochitidwa. Osowa kudwala anati osapitirira 1% ya makanda obadwa kumene.

Kuwonetsera kunja chitsanzo matenda amakhala V woboola pakati, mu mawonekedwe a mapini kapena mizere wavy. Nthawi zambiri unakhazikitsidwa pa mbali imeneyi ya thupi:

• kumbuyo;
• pa mbali;
• mapewa;
• mutu.

Kuzindikira vuto

Mzere Blashko noticeable pamene munthu irradiated ndi kuwala ultraviolet, koma moyo wa kawirikawiri akudutsa Kupenda zimenezi. Kuphunzira chikhalidwe cha thupilo adzayamba kale mu magawo pang'onopang'ono kwa matenda. Makanda obadwa kumene, mawanga chowala wa hypopigmentation thupi ovuta kuona. The mwana amapeza ndi kusintha kwakukulu kwa khungu mu zaka zingapo.

Pa dziko la maselo anakhudzidwa ndi ya DNA. Ngati chiri chosiyana kwambiri zigawo moyandikana a pakhungu, zolakwika anati mu nsalu ochekenera. Choncho hypopigmentation angaoneke zinthu zotsatirazi:

• Wachisokonezo mawanga - chidwi sayansi chifukwa cha nyumba ya m'goli. The chithunzi limasonyeza anaona akalumikidzidwa zovuta mu mawonekedwe a magulu, maselo Chess.
• Mukuchitika - kuwonetseredwa malo amodzi mu malo ena.
• Zowombetsa mkota - akhozanso kukopeka ndi matenda a ziwalo.

N'chifukwa chiyani tiyenera kuphunzira zojambula pa khungu?

Madokotala ayamba kapangidwe kusanthula zimakhala pa mavuto kuonekera pa khungu. Apa chizindikiro chachikulu ndi mzere Blashko, nthendayo ankafufuza za matenda zolondola. Izi umakhala wofunika pamene zotsatirazi mavuto dermatological:

• chimerism;
• mosaicism;
• zoster;
• nevus;
• khansa.

mawonekedwe zovuta ndi zofunika kokha ku mbali kafukufuku, chifukwa layman ndi, kusanthula zimenezi sanabadwe kuyambitsa mfundo zina zokhudza matendawa. Asayansi kukonzekera kuti awulule cholinga cha dongosolo pa thupi la munthu. Mwina anapeza kudzatithandiza kuthetsa zotsatira za osowa khate.