Myeloproliferative matenda: zimayambitsa, zizindikiro, matenda

Myeloproliferative matenda zimayambitsa, zizindikiro, matenda a tikambirana kenako, amapanga gulu la limati, imene mafupa, pali chinawonjezeka yopanga thrombocytes, erythrocytes kapena leukocytes. Okwana pali mitundu isanu ya pathologies.

mwachidule

Mafupa zambiri amachita m'badwo tsinde (mwana) maselo. Patapita kanthawi iwo okhwima, yodzala. A selo tsinde akhoza kukhala poyambira mapangidwe mitundu iwiri ya zinthu: angapo lymphoid ndi myeloid maselo. maselo mwana ndi zithunzi mapangidwe leukocytes. Mwa miyambo ya mutu wakuti myeloid amapangidwa:

• Erythrocytes. Iwo amanyamula mpweya ndi zakudya zina kugwirizana ziwalo ndipo zimakhala.
• Leukocytes. zinthu izi ndi udindo chitsutso ndi pathologies ena opatsirana.
• Othandiza. Maselo amenewa kupewa magazi, mawonekedwe kuundana.

Isanafike kusintha mu maselo ofiira, maselo oyera kapena othandiza magazi kuundana, mapulaniwo maselo kupita kupyolera magawo angapo. Ngati alipo, matenda myeloproliferative, wambirimbiri choyambira aumbike mwa mitundu chimodzi kapena zingapo maselo anapanga. Childs kudwala pang'onopang'ono zokwanira ndi kuwonjezeka zinthu owonjezera magazi.

Gawo

Mtundu kumene kungakhale matenda myeloproliferative zimadalira kuchuluka kwa erythrocytes, maselo othandiza magazi kuundana kapena leukocytes. Nthawi zina, thupi Amowabu owonjezera zinthu za mitundu kuposa wina. Kudwala lagawidwa:

• Matenda neutrophilic khansa.
• Polycythemia.
• Matenda myelogenous khansa.
• N'kofunika thrombocytopenia.
• Idiopathic (aakulu) myelofibrosis.
• Eosinophilic khansa.

siteji pathological

Matenda matenda myeloproliferative akhoza lidzasinthidwa khansa pachimake. chikhalidwe ichi amakhala ndi owonjezera maselo oyera. Matenda myeloproliferative matenda alibe yeniyeni staging chiwembu. miyeso achire zimadalira mtundu wa kudwala. Pankhani pathways, ndi matenda myeloproliferative angayambe imodzi mwa njira zitatu:

• Kumera mu zimakhala ena. Pankhaniyi, khansa kufalikira kwa ozungulira zigawo wathanzi, kumenya iwo.
• Lymphogenous njira. matenda Myeloproliferative amatha kulowa mu dongosolo lymphatic ndi nsupa ake anagawira pa zimakhala zina ndi ziwalo.
• Hematogenous njira. Maselo chotupa chija kudutsa mu capillaries ndi mitsempha kuti kudyetsa zimakhala ndi ziwalo.

Pamene kufalikira kwa maselo chotupa, mwina n'kupanga latsopano (sekondale) zotupa. Zimenezi amatchedwa metastasis. Secondary kwa zotupa chachikulu, ndi mtundu womwewo wa khansa. Mwachitsanzo, pali kufala kwa maselo leukemic mu ubongo. Inapeza zinthu chotupa. Iwo amanena kuti khansa, osati khansa ya mu ubongo.

Zizindikiro za kudwala

Kodi matenda myeloproliferative? Zizindikiro za matenda otsatirawa:

• kuwonda, matenda a anorexia.
• Kutopa.
• M'mimba ululu komanso kudzimva kudya chakudya machulukitsidwe. Last chikwiyire zikuluzikulu ndulu (splentomegaliey).
• Kutengera za magazi, kufinya, kapena zizindikiro za thrombosis.
• Mkhutu kutsitsimuka.
• Olowa ululu, kutupa, chikwiyire gouty nyamakazi.
• Akamaganizira lapansi.
• Soreness lamanzere chapamwamba nusu la pamimba ndi kumanzere phewa, lomwe ndi zotsatira za kutupa kapena infarction a ndulu ya.

kafukufuku

Myeloproliferative matenda magazi wapezeka pa maziko a zotsatira zasayansi. The kafukufuku zikuphatikizapo zinthu zotsatirazi:

• Kuphunzira mtima. Pankhaniyi, katswiri ndiyo chikhalidwe ambiri amasonyeza zizindikiro za kudwala (kutupa, mwachitsanzo), komanso kusonyezedwa, panalibe munthu wathanzi. dokotala imafunanso za moyo wa wodwala matenda ndi zizolowezi zoipa, mankhwala.
• Anawonjezera KLA. zitsanzo zosankhidwazi magazi ikuchitika kudziwa:
  
  - chiwerengero cha othandiza magazi kuundana ndi maselo ofiira;
  - chiŵerengero ndi chiwerengero cha leukocytes;
  - mlingo wa hemoglobin;
  - buku limene wotanganidwa ndi maselo ofiira.

• Chiyembekezo ndi mafupa biopsy. Pa ndondomeko, nkhungu dzenje singano umayamba mu sternum kapena iliac fupa. mpheto Zimenezi zimathandiza kuti kutenga mafupa nyemba ndi minofu komanso magazi. chuma bwinobwino ndi maso pamaso pa maselo nthenda mu izo.
• Cytogenetic kusanthula. Ndondomeko imeneyi zimathandiza inu kudziwa kusintha DNA lapansi.

Matenda myeloproliferative matenda: Chithandizo

Pakali pano, pali njira matenda angapo. Chimodzi kapena njira zina amasankhidwa malingana ndi mmene wodwalayo ndi mawonetseredwe kuti ayende matenda myeloproliferative. Mankhwalawa angathe kuperekedwa muyezo - kutsimikiziridwa zochitika kapena experimental. Yachiwiri ndi kuphunzira kugwiritsa ntchito njira zosiyanasiyana latsopano.

phlebotomy

Ndondomeko kutenga magazi kuchokera mu mtsempha wa. chuma ndiye anatumizidwa ku amuzolengedwa kusanthula wamba. Nthawi zina, phlebotomy Kwalamulidwa kwa odwala amene ali ndi matenda myeloproliferative. Chithandizo Pankhaniyi walangizidwa kuchepetsa chiwerengero cha erythrocytes.

kupatsidwa zinthu za m'mwazi apheresis

Njira imeneyi ndi wofanana ndi m'mbuyomu. kusiyana kumeneko ikuchitika kuchotsa othandiza magazi kuundana owonjezera ntchito zipangizo zina zapadera. Wodwala amatenga magazi amene anadutsa olekanitsa a. Iye akugwirizira othandiza magazi kuundana. "Kutsukidwa" magazi kubwerera ku mtima.

kuikidwa

njirayi ndi magazi. Pankhaniyi m'malo ena zinthu zina. Makamaka, wodwala m'malo maselo awo anawonongedwa ndi kuonongeka zikuchoka kuikidwa maselo oyera, maselo ofiira ndi maselo othandiza magazi kuundana.

Morning

Njira imeneyi imaphatikizapo ntchito mankhwala cytotoxic. zochita zawo umalimbana kuwonongedwa kwa maselo chotupa kapena liwiro kukula kwa zotupa. Pakuti m'kamwa, mtsempha kapena mu mnofu ntchito mankhwala, zosakaniza awo yogwira kudutsa mu makope zokhudza zonse, kuchotsa zinthu pathological. Zimenezi zimatchedwa zokhudza zonse mankhwala amphamvu. njira Regional ndi chiyambi zikutanthauza mu ngalande msana, bwanji chiwalo kapena thupi M'mimbamo mwachindunji.

mankhwala cheza

Chithandizo ikuchitika ntchito mkulu pafupipafupi x-ray kapena cheza zina. Cheza mankhwala akhoza kukwaniritsa kuwonongedwa mtheradi maselo chotupa ndi m'mbuyo kukula kwa zotupa. Zochita ndi mitundu iwiri ya mankhwala. cheza kunja mankhwala ndi padzuwa la wagawo ndi, inali pafupi ndi wodwala. Pamene eni kudzazidwa ndondomeko ikuchitika ndi nyukiliya zinthu masingano, catheters, timachubu, amene ndiye jekeseni mwachindunji mu chotupa kapena mu zimakhala ndi ili mozungulira icho. Njira yomwe idzagwira ntchito katswiri, malingana ndi mlingo wa chotupa chija kwa ndondomekoyi. Odwala amene anapezeka ndi myeloproliferative matenda magazi irradiated, monga ulamuliro, m'dera ndulu.

Morning ndi kupatsidwa zina maselo

Njira imeneyi mankhwala ntchito mankhwala mlingo waukulu ndi M'MALO anakhudzidwa antitumor kanthu maselo atsopano. zinthu mwana ali ku mwiniwake kapena wodwala ndi mazira. Nditamaliza Morning, anadzetsa thupi chuma kusungidwa. Zaluso maselo zimayamba kukhwima ndi yotithandiza mapangidwe maselo atsopano magazi.

nthawi kuchira

Pambuyo mankhwala, wodwalayo ayenera kukaonana ndi dokotala nthawi zonse. Kuonanso mphamvu ya mankhwala ukafunidwe kuchita mndandanda wa ndondomeko ntchito kale pamaso atasankhidwa. Malinga ndi zotsatira, kusankha kupitiriza, akamaliza kapena kusintha mankhwala chakudya. Kafukufuku ayenera kubwereza nthawi zonse, ngakhale nditamaliza njira achire. Iwo adzalola inu kuti aone mmene zochitika ndi kudziwa kumwa.