Mankhwala 'Atenolol Nycomed'

Mankhwala "Atenolol Nycomed" pali mankhwala, ndi mayiko consonant ndi dzina la "Atenolol". M'chilankhulo cha akatswiri pharmacologists amapanga mankhwala zikuoneka ngati (RS) -4- (2-hydroxy -3- (isopropylamino) phenyl-acetamide. Mapale "Atenolol" zikuimira oboevypuklye mankhwala TACHIMATA wa mtundu woyera, kuti ndi kapisozi mawonekedwe. Thupi waukulu amaperekedwa mphako pa yopuma pa dzanja limodzi, pali zizindikiro AV55 ndi AV57.

Mu piritsi limodzi, malingana ndi mtundu kumasulidwa anyamula makumi asanu kapena zana mamiligalamu wa atenolol. Monga zigawo wothandiza ntchito talc, gelatin, propylene glycol, titaniyamu dioxide, mankhwala enaake a stearate, ipromeloza 2910 (15sP), chimanga wowuma, sodium lauryl sulphate ndi katundu mankhwala enaake a carbonate.

Medicine "Atenolol Nycomed" ntchito ngati njira beta1-kusankha (cardioselective) adrenoceptor kutsekereza wothandizira, Kakhungu ofunika ntchito si. chida Izi zikusonyeza antianginal, antiarrhythmic ndi hypotensive kwenikweni. Iwo amatha kutsekereza zolandilira beta-adrenergic mitima, kuchepetsa m'mnyewa wamtima kukondoweza a gulu wachifundo dongosolo autonomic mantha ndi makatekolamaini, amene zimafala m'magazi. Medicine "Atenolol" zimakhudzanso kuchepetsa nkusani automaticity, normalizes mlingo mtima amaima ndi pa thupi. Izi limakhazikitsa ndondomeko ndi malemeredwe wa contractility m'mnyewa wamtima, liwiro zimakhudzanso AV-conduction. Mu ntchito zake pali kuchepa kufunika m'mnyewa wamtima oxygen. Akutsutsana amakhudza mwadongosolo ntchito mankhwala "Atenolol" pa kutsitsa magazi. Olimba cha mphamvu antihypertensive amapezeka ndi kumapeto kwa sabata lachiwiri la phwando.

Kukonzekera "Atenolol Nycomed" pa njira m'kamwa phwando angathe odzipereka mu kapepala m'mimba mu buku la 50-60% ya mlingo kutumikiridwa. Excreted mu mkodzo ndi theka moyo wa maola 6-7. nthawi awa odwala ndi kuwonongeka aimpso, malingana ndi mlingo wa kusefera glomerular.

Zikuonetsa mankhwala ndi "Atenolol Nycomed" mitundu ya matenda oopsa ndipo tachyarrhythmias (kuphatikizapo nkusani). Ikani mankhwala komanso ngati wothandizira njira kwa kuukira angina.

Mlingo tsiku la mankhwala kwa akulu mankhwalawa angina ndi matenda oopsa ukufika 50-100 mg. mapiritsi chikuonetseratu wapangidwa ndi kawiri pa tsiku Popeza kuti mlingo tsiku sayenera upambana 200 mg. Kusamba pansi mankhwala ayenera kukhala zazing'ono kuchuluka kwa madzi.

Mankhwalawa amagwiritsidwa ntchito mogwirizana ndi malangizo a dokotala nawo. Self-mankhwala sikuloledwa. Mankhwala "Atenolol Nycomed" ali mavuto. Dongosolo mtima mungachite maonekedwe a chisokonezo bradycardia, AV-conduction, mungachite zomverera za paresthesia ndi miyendo ozizira, zina kuwonetseredwa zizindikiro za matenda a mtima. thirakiti m'mimba amachitira zoipa kwa nseru mankhwala, kudzimbidwa, m'mimba, youma pakamwa (osowa), dongosolo endocrine - chitukuko zotheka chikhalidwe cha hypoglycemic mu odwala matenda a shuga, urogenital dongosolo - zotheka kuchepa potency. CNS chowawa zochita akhoza kusonyeza mu mutu, chizungulire, matenda tulo, maganizo, malingaliro a kutopa. N'zothekanso matupi awo sagwirizana zochita, kuyabwa ndi redness. Nthawi amveke thukuta, kuchepetsa kuichotsa katulutsidwe madzimadzi ankalembedwa yatsoka a conjunctivitis.

Komanso, pali a contraindications. Mu mndandanda lawo kumaphatikizapo magawo munthu kulephera aakulu mtima, bradycardia, hypotension, chodziwa kudziwa mankhwala, ndi ena.

Kusunga mankhwala mu malo ouma, kutetezedwa ku kuwala, osati ana. Malo kutentha kwa 25 ° C. mankhwala A amakhala katundu zaka zisanu.