Mankhwala "Aklasta". malangizo

Mankhwala "Aklasta" analogues wa mankhwala ( "Veroklast", "Blaztera", "Zolendronat-Teva", etc.) angathe m'mbuyo kuwonongedwa kwa minofu fupa. Zelendronovaya asidi - mbali yogwira - ali m'gulu la a bisphosphonates (zinthu zenizeni popewa imfa fupa).

Mankhwala "Aklasta". mafotokozedwe

medicament The amachoka mu mawonekedwe a njira yothetsera kulowetsedwa.

Pambuyo makonzedwe mtsempha, mbali yogwira ndi anagawira mu minofu fupa mofulumira. Ngati bisphosphonates zina, zelendronovaya asidi isanafalikire makamaka m'madera a fupa resorption (chionongeko).

Ndi kuteteza chiwonongeko cha, zosakaniza yogwira si kusokoneza katundu makina, ndondomeko mapangidwe ndi fupa mineralization.

Mankhwala "Aklasta". Malangizo: umboni

mankhwala Kwalamulidwa kwa fupa matenda Paget a (deforming osteitis), postmenopausal kufooka kwa mafupa (kuchepetsa mosavuta fractures mu nsana, femur ndi mafupa ena ndi kupititsa mchere awo kachulukidwe), chifukwa kupewa fractures mafupa pambuyo kuvulala mu ntchafu olowa.

"Aklasta" njira. Malangizo: mlingo kamwedwe

Pamaso utsogoleli wa mankhwala pofuna akadakwanitsira hydration (madzi machulukitsidwe) wa chamoyo. Zimenezi n'zofunika kwambiri mu ntchito mankhwala diuretic.

Pakuti kupewa fractures pambuyo choipa ndi ntchafu ndi mankhwala a kufooka kwa mafupa postemenopauznogo mankhwala "Aklasta" mtsogoleri amalimbikitsa kutumikiridwa ndi kulowetsedwa mtsempha kamodzi pachaka mu kuchuluka kwa mamiligalamu zisanu (kamodzi). mankhwala ayenera imodzi kutenga zowonjezera kashiamu ndi vitamini D.

Mankhwalawa matenda Paget a mtsempha medicament "Aklasta" analimbikitsa zolimbitsa malangizo mlingo mamiligalamu asanu pa Botolo zana ya amadzimadzi njira kutumikiridwa monga limodzi kulowetsedwa mtsempha ntchito dongosolo. Administration nthawi - zosachepera maminiti khumi ndi asanu, liwiro ayenera nthawi zonse. Chifukwa chakuti matenda Paget a amakhala ndi chiwonongeko pang'onopang'ono kwa fupa, odwala onse ndi kudwala ili akulimbikitsidwa kudya cha zina tsiku chofunika vitamini D ndi calcium pa masiku khumi pambuyo kulowetsedwa wa.

Utsogoleli loyamba la mankhwala "Aklasta" zimayambitsa nthawi yaitali chikhululukiro deforming osteitis. Pakali pano, lachindunji kukonzanso chithandizo cha matenda Paget a palibe. Komabe, zimenezi n'zotheka, ngati wodwalayo ali ndi kumwa. chitukuko Secondary wa kudwala kwa amakhala ndi zinthu zotsatirazi: palibe normalization wa phosphatase zamchere ku seramu, kuchuluka kwa mphamvu mlingo wake, ndi pamaso pa zizindikiro matenda a matenda Paget a, kuzindikiridwa miyezi khumi pambuyo ntchito ya "Aklasta" mlingo.

mankhwala ali osavomerezeka chifukwa odwala ndi ntchito aakulu aimpso.

Okalamba ndi odwala ndi kusintha matenda chiwindi ntchito mlingo chofunika.

Popeza deta pa chitetezo ndi efficacy a "Aklasta" mankhwala odwala osakwana zaka khumi ndi zisanu ndi zitatu, iwo mankhwala si kutumikiridwa.

Pambuyo kumayambiriro mankhwala angayambe malungo, matenda chimfine, kutopa, kutupa zikamera wa (osowa), malaise, asthenia, kuzizira. Pafupipafupi zosiyanasiyana chokhwima sankaoneka ngati mutu, ulesi, chizungulire, kupuma movutikira. Nthawi zina akhoza kudzakhala paresthesia, syncope, kugwedeza, somnolence. Odwala angaone kupweteka mafupa msana. Mwina chitukuko cha myalgia, arthralgia, dyspepsia, kusanza ndi zotsatira zina zoyipa.

Mankhwala ali contraindicated pa mkaka wa m'mawere, hypocalcemia, mimba, hypersensitivity.