Kuthetsa - ndi chiyani ichi? Features

Kuyambira kalekale anthu akhala ankaganiza kuti chilengedwe m'mimba, ndi wosabala malo izo microflora. Mmimba, ndi wokhutira mkati - asidi, kapena kungoti sanakhale ndi moyo limodzi chamoyo. Kudziwika Helicobacter pylori kapepala kakuti m'mimba zasinthiratu lingaliro la chikhalidwe cha matenda m'mimba: gastritis, duodenitis, zilonda muzituluka ndi zilonda mmatumbo, khansa m'mimba ndi mankhwala. M'nkhani ino tikambirana mwatsatanetsatane zimene inayamba. Ndi njira imene chithandizo wakhala wotchuka kwambiri m'zaka za posachedwapa.

Ulendowu m'mbiri ya Helicobacter pylori

Ndipotu, bakiteriya anatulukira nthawi yaitali osati kamodzi. Kwa nthawi yoyamba zimenezi zachitika kumapeto kwa zaka za m'ma lomaliza. chaka cha 1886. Jagiellonian University Professor V. Yavorsky kudziwa mabakiteriya khalidwe mwauzimu mawonekedwe mu nkhani muzituluka. Iye anapereka dzina la bakiteriya Vibrio rugula, ndipo ananena kuti n'chofunikira mu chitukuko cha matenda muzituluka.

Komabe, chidwi chifukwa sipanatenge Yavorsky ntchito m'dera kuchipatala. patatha zaka zisanu ndi wasayansi Italy D. Bidzodzero anasolola tizilombo wosiyana ndi kapepala m'mimba mwa galu. Yotsatira, yemwe anati pamaso pa mabakiteriya maselo m'mimba kwa odwala opareshoni anam'peza anali Professor Morozov Moscow. Anali kale mapeto a 70s Mu zaka zapitazo.

zoyesayesa Komanso kuti mwanjira amafotokoza m'kagulu, kukula kwa zasayansi ndi kufufuza anonymous bakiteriya wakhala kucitika mu 1979 ndi 1981 ku Australia Marshall ndi Warren. Ndipo iwo anapambana. Marshall unachitikira zinachitikira bwino kudziletsa matenda a Helicobacter pylori ndi machiritso a helicobacter gastritis yotengedwa ndi njira ya chithandizo iwiri ndi "mankhwala a metronidazole" ndi mchere bismuth.

Njira imeneyi imagwiritsidwa maziko a kuthetsa yamakono ya Helicobacter pylori. A ofufuza wolimba mu 2005 analandira Nobel Prize mu Medicine.

Dzina la Helicobacter pylori chamoyo anali mu 1989, komanso kufotokoza wathunthu ndi gulu. Mwauzimu bakiteriya malo wasankha "mlonda" wa m'mimba ( "pylori" - kuchokera Greek "mlonda") infects m'madera onse a duodenum ndi m'mimba. Mu kuchuluka kwambiri a gastritis, duodenitis, zilonda zonse matumbo ndi zilonda mmatumbo mpaka khansa ndi mlandu wa bakiteriya izi.

Kuopsa kwa matenda ndi Helicobacter pylori?

Helicobacter pylori, kukhala thirakiti m'mimba wa munthu kapena nyama pores khalidwe pafupifupi. Pa kulephera pang'ono mu chitetezo cha m'thupi kapena zotsatira chokhala ndi kuperewera kwa zakudya m'thupi kapena zizolowezi salimbikitsa adamulowetsa bakiteriya amakhala aukali. Ndi chiyani icho oopsa? Kukhala Kakhungu mucous ziwalo mkati - m'mimba ndi duodenum - tizilombo bakiteriya kuchita pa izo.

Kumayamba kuchuluka kumasulidwa zinsinsi, amene zikuwononga amakhudza minofu m'mimba. Mucous iwo amakhala lotayirira, wosweka, pali mbali kwambiri chofuna mapangidwe zilonda. Matenda gastritis chifukwa cha tizilombo bakiteriya Helicobacter pylori gulu, mosiyana ochiritsira makina gastritis, si amenable kuwachiritsa ndi njira zinazi.

Helicobacter pylori likulowerera zigawo zonse zakuya minofu, potero mulibe mankhwala ambiri (mankhwalawa ndi wosakhazikika kuti acidity). Chotero vandalnye zochita zake chifukwa njira sizingasinthe mu mucosa Mwachitsanzo, chikhalidwe precancerous, ndipo mwachindunji, chitukuko cha Oncology. Popewa izi, ntchito kuthetsa Helicobacter.

Matenda a Helicobacter pylori kapepala kakuti m'mimba

Ngati wodwala anadandaula kuchita nseru, kudzimbidwa, kutentha, ululu, mavuto ndi mpando, ndi kusapeza chowawa m'dera epigastric - zimasonyeza mwachindunji kuti aone pamaso pa chamoyo Helicobacter pylori. Kusanthula lendi ndi:

• magazi, kusanthula ambiri oteteza ndi, kuphatikizapo pamaso pa H. pylori;
• chopondapo kusanthula pamaso pa mabakiteriya zinyalala;
• mpweya mayeso zachokera mtima wa ndende amoniya mu mpweya;
• cytologic kusanthula.

The njira yodalirika ya Kupeza Vuto matenda ndi minofu biopsy wa mucosa muzituluka ndi zilonda mmatumbo. nsalu zikutengedwa kusanthula ndi endoscopy.

zikuonetsa kuthetsa

Monga tanenera kale pamwambapa, kuthetsa - njira kuthana ndi bakiteriya muzituluka.

Kuthetsa ikuchitika odwala pathologies amenewa:

• Zizindikiro chilonda m'mimba ndi duodenum;
• udindo positi resection (opaleshoni kuti achotse khansa);
• limati precancerous ndi matupi minofu ya manja;
• lymphoma.

Pachiopsezo anthu amene achibale zowawa khansa. Analimbikitsa kuthetsa mankhwala ndi odwala ndi gastroesophageal matenda Reflux ndi zinchito dyspepsia.

njira kuthetsa

Kuthetsa - ndi kuwonongedwa, kuthetsa (English inayamba.). Izi muyeso, cholinga kuononga kachilombo ndi Helicobacter pylori thirakiti m'mimba. njira mankhwala akusonyeza odwala ndi aakulu chapamimba chilonda kapena mmatumbo chilonda. Kwenikweni umenewu chagona pa njira zakudya mankhwala mu ndondomeko yeniyeni.

Isanayambe Maphunzirowa wochititsidwa liwunikidwenso chapamimba mucosal minofu pamaso pa maselo zilonda.

Helicobacter pylori kuthetsa ali mitundu ingapo:

• rekodi, kumene amagwira ntchito mankhwalawa kulandira njira imodzi yokha, kawirikawiri medicaments zochokera salt bismuth, kapena maantibayotiki;
• Awiriwa mankhwala wapawiri (vismutosoderzhaschee mankhwala kuphatikiza mankhwala);
• triplet, monga dzina lake likunenera, chithandizo ndi mankhwala atatu (bismuth, maantibayotiki ndi nthumwi imidazole gulu);
• kvadriplet, kupanga zinayi, mmene ndi triplet zovuta anawonjezera PPI mankhwala (blockers asidi hydrochloric).

Rekodi-kuthetsa - izi pafupifupi konse ntchito njira mankhwala chifukwa cha kupanda ake (m'munsimu 50%). Iye anali otchuka pa chiyambi cha kutsegula ndi woyamba zatsopano helikobakterialnoy azichitira matenda.

Kuthetsa ntchito mankhwala awiri ali ndi dzuwa la kutaya helicobacter 60%, ndi zocheperatu mu zenizeni lero ankachita. ntchito lero kuthetsa ndi chiyani? Chithandizo regimens ntchito.

Tripletoterapiya zikuphatikizapo pawiri bismuth, maantibayotiki (amoxicillin ndi kunadetsa ntchito klaritomitsin) ndi imidazoles (ichi fungicides).

The njira ya mankhwala anayi - onse formulations pamwamba kuphatikiza zoletsa purotoni mpope (gulu mankhwala antiulcer umalimbana kuchepetsa chapamimba asidi kupanga). Njira kwa dzuwa ake ndi ntchito akalozera 90% ndipo 95% motero. Naŵa kuthetsa bwino Helicobacter kungakhale.

Mankhwala ntchito kuthetsa

Chifukwa malo acidic nullifies zotsatira za mankhwala ambiri, mndandanda wa mankhwala kuthetseratu yochepa:

• mankhwala;
• antiinfectives;
• vismutosoderzhaschie mankhwala;
• zoletsa purotoni mpope;
• probiotics ndi prebiotics.

Maantibayotiki zofala kwambiri ntchito mankhwala kuthetsa

Kodi kuyamba kuthetsa? Mankhwalawa ndi awa:

• "Amoxicillin" kapena "Flemoksin Soljutab" - Penicillin gulu, ali oyenera odwala ambiri ali osavomerezeka ntchito woyembekezera, aimpso kulephera.

• "Amoxiclav" - osakaniza amoxicillin ndi asidi kavulonovoy, ndi wodziika sipekitiramu mankhwala tikulimbikitsidwa ntchito yochenjera mu impso pathologies wodwalayo, pa mimba zimayambitsa mankhwala dysbiosis kwambiri.
• "Clarithromycin" kapena "Klatsid" - otsika poizoni mankhwala mankhwalawa gulu lonse osiyanasiyana otchuka kwambiri kuthetsa, ndi contraindicated mu makanda mpaka miyezi isanu ndi umodzi, amayi apakati, ntchito mosamala odwala ndi insufficiency aimpso kapena kwa chiwindi.
• "Azithromycin" - njira ina "Klaritomitsinu" ndi zotsatira kochepa mbali, komabe zochepa polimbana helicobacter pylori.

Maantibayotiki "angamwe tetracycline" ndi "Levofloxacin" ntchito zochepa zambiri ndipo nthawi kumene mankhwala tatchulawa alibe mukufuna. Formulations ya tetracycline gulu chionetsero kanthu aukali mawu mavuto pambuyo kuthetsa Helicobacter Choncho kawirikawiri ntchito.

mankhwala antibacterial ndi odana infective kwa kuthetsa ndi

"Metronidazole" - odana infective chemotherapeutic wothandizila nitromidazolovoy gulu poizoni kwambiri, mosamalitsa atakwatirana ndi mowa ndipo amaletsedwa pa mimba.

"Makmiror" kapena "Nufuratel" - kupanga mankhwala antibacterial, amagwiritsidwanso ntchito ngati kulephera kwa "Metronidazole".

Vismutosoderzhaschie mankhwala

"De-Nol '- izi ndi zimene mankhwala yasonyeza digiri apamwamba neutralizing kukhudzana Helicobacter. "De-Nol 'dissolves ndi akulowa ya ndulu amatope mu zigawo kuya kwa chiwalo akhudzidwa. mavuto obwera mbali ali pafupifupi ayi, komanso contraindications (kupatula, mwamwambo, mimba).

Pasanathe amagwiritsidwa ntchito pa matenda a Helicobacter mchere mankhwala bismuth:

• bismuth subsalicylate;
• bismuth subnitrate.

Kukonzekera zochokera salt bismuth ntchito zochizira matenda a m'mimba, pamaso kutsegula kwa Helicobacter pylori. mankhwala awa ndi kugonjetsedwa kwa malo acidic m'mimba. mankhwala Bismuth pa mucosa kuonongeka pamwamba kupanga filimu chochokera chilengedwe zikuwononga, kuchepa acidity ndi kulimbikitsa amamuyambitsa timabala oyambirira pamalo anakhudzidwa.

Pamene inu kutsegula Helicobacter pylori mankhwala bismuth anasonyeza zotsatira zidzasintha pa yimitsira ndi chiwonongeko cha bakiteriya imeneyi.

Formulations DZENJE gulu ntchito kuthetsa ndi

purotoni mpope zoletsa (PPIs) ili yofunika ku zotsatira zovuta pa Helicobacter pylori. PPI mankhwala ndi mtundu wa zotsatira mankhwala ochotsa asidi, amachepetsa ndewu ya chilengedwe acid. Mabakiteriya Kafukufuku wasonyeza kuti kunja chilengedwe acidic umafa. Choncho, PPI kulenga zinthu kosati chifukwa omasuka kuli mabakiteriya mu zovuta ndi bismuth, "a metronidazole" ndipo ukuwonjezeka mankhwala bwino kuthetsa Helicobacter pylori kuti 95% ndi pamwamba. mankhwala njirazi ndi izi:

• "Omez" ( "omeprazole");
• "Nolpaza";
• "Rabeprazole";
• "Pantoprazole" ndi zina zotero.

kutanthauza "Omez" amene anapatsidwa zambiri. Blockers kapena purotoni mpope PPI kubweza ntchito ya katulutsidwe wa zopangitsa m'mimba.

Normalization ya m'mimba thirakiti microflora pambuyo kuthetsa Helicobacter

Ndinakumana ndi mankhwala nthawi zambiri chimawononga matumbo ndi m'mimba. Choncho, pambuyo ndondomeko zofunika siziwononga kuthetsa anachititsa kwa thupi. Kuti tichite zimenezi, pali mankhwala othandiza monga probiotics kapena prebiotics yasonyezedwa dysbacteriosis, flatulence, kutsekula m'mimba, etc. Zikuphatikizapo .:

• "Laktoferon";
• "Linex";

• "Hilak forte";
• "Bifidumbacterin";
• "Atsipol" ndi zina zotero.

Probiotics ndi Prebiotics - chikhalidwe mwapadera, mogwirizana complementing ntchito ya wina ndi mzake. magulu onse zimakhala zolimbikitsa kwambiri pa chamoyo ndi normalizing nyama matumbo. Kusiyana pakati pa iwo ndi kuti probiotics - wamoyo chikhalidwe cha tizilombo opindulitsa. Prebiotics chomwecho - organic mankhwala. Woyamba mwachindunji "kukula" ndi microflora akufa, wachiwiri - kulenga zinthu yabwino kwa izi. Iwo amafuna kutenga pambuyo inayamba.

kupewa matenda

Helicobacter pylori zobisika chonyamulira kungakhale lililonse. The bakiteriya amakhala m'mimba, intestine ndi m'kamwa M'mimbamo wa munthu kapena nyama zaka ndipo alibe kuonekera.

Kutsegula mabakiteriya kumachitika chifukwa ndi kulephera m'thupi mwapanikizika, makhalidwe oipa (mowa, kusuta fodya), zakudya akamakonda ndi ululu epigastric kumaonekera. Mitundu ina Helicobacter zingakhudze chiwindi.

Pomaliza

Kuwonongeka kwa matenda TV amapezeka ndi kukhudzana kapena pogwiritsa ntchito nkhani za m'banja. Muyenera amatsatira malamulo a ukhondo, kuti tichepetse kuipitsidwa wa lachitatu chipani. Ndiye izo sikutanthauza kuthetsa Helicobacter pylori.