Zolemba za "Koraksan": ndondomeko ndi malangizo ogwiritsidwa ntchito

Kodi ziganizo za Koraksan ndi ziti? Yankho la funso ili lomwe mungapeze m'zinthu za m'nkhani ino. Kuonjezerapo, tidzakudziwitsani zomwe zikufunika pa mankhwalawa, momwe ziyenera kutengedwa, ndi zina zotero.

Zambiri zokhudza mankhwala

Mapiritsi a Koraxan ndi kukonzekera komwe kumachepetsa kuchepa kwa mtima. Mankhwalawa ali ndi mankhwala omwe amagwiritsa ntchito ngati ivabradine hydrochloride, komanso othandizira ena monga lactose monohydrate, magnesium stearate, corn starch, maltodextrin ndi colloidal silicon dioxide.

Pharmacological action

Zithunzi za Coracsan, komanso kukonzekera zokhazokha, zimawongolera kuthamanga kwa mtima mwachindunji komanso mwachindunji njira zothetsera vutoli, zomwe zimayambitsanso kuwonongeka kwa chiwonongeko cha diastolic. Mankhwala othandiza omwe amagwira ntchitoyi amagwiritsa ntchito njira zothandizira anthu pa atrioventricular ndi intraventricular paths, komanso pogwiritsa ntchito ventricular repolarization ndi contractuous contractual contractiles.

Mwazinthu zina, ivabradine hydrochloride ikhoza kugwirizana ndi retinal IF-njira, zofanana ndi njira za mtima za IF, zomwe zimagwira nawo pangoyamba kusintha kwa kanthawi kooneka m'maso. Komabe, mbali yaikulu yamagetsi ya mankhwalawa ndi luso lochepetsa kuchepa kwa mtima.

Zizindikiro za kugwiritsa ntchito mankhwala

Kodi ziganizo za "Koraksan" zikugwiritsidwa ntchito, komanso chida chokha? Mankhwalawa amalembedwa m'mabuku otsatirawa:

• Stable angina. Matenda a matendawa mothandizidwa ndi mankhwalawa amachitikira kwa odwala omwe ali ndi chikhalidwe chodziwika bwino pakakhala kusagwirizana ndi kusagwirizana kwa beta-blockers, komanso kuphatikiza nawo.
• Kulephera kwa mtima (matenda). Pogonjetsedwa kotero, kukonzekera ndi zofanana za Coraxan zimagwiritsidwa ntchito kuchepetsa mavuto a mtima wa mtima. Ndipotu, kufa kwakukulu kwa odwala kumayenderana ndi matendawa.

Kusiyanitsa kwa kugwiritsa ntchito mankhwala "Koraksan"

Mafotokozedwe okonzekera "Koraksan" ndi mankhwala enieniwo sali ovomerezeka kuti agwiritsidwe ntchito pazifukwa zotsatirazi:

• Hypersensitivity kwa ivabradine hydrochloride kapena mbali iliyonse yothandizira ya wothandizira;
• Angina wosakhazikika ;
• Kusokonezeka kwa mtima;
• Bradycardia (ndiko kuti, ndi kuthamanga mtima kwa maola 60 pamphindi pa mpumulo);
• Matenda a myocardial (acute);
• Kulephera kwenikweni (kwakukulu);
• Matenda oopsa a hypotension (pa kupweteka kwa m'mimba osakwana 90 mm Hg ndi diastolic - zosakwana 50 mm Hg);
• Kufooka kwa nthenda ya sinus;
• Kukhalapo kwa electrocardiostimulator;
• Sinoatrial yatsekedwa;
• Kulumikizana ndi mimba;
• Atrioventricular blockade ya digiri ya 3;
• Kugwiritsiridwa ntchito panthaŵi imodzi mwazitsulo zolimba za cytochrome system isozymes (mwachitsanzo, kukonzekera "Ketoconazole", "Erythromycin", "Itraconazole", "Josamycin", "Clarithromycin", "Ritonavir", "Telithromycin", "Nefazodone" ndi "Nelfinavir");
• Zochepa (chitetezo ndi kugwiritsidwa ntchito kwa chida ichi kwa zaka 18 sizinaphunzirepo);
• Kusagwirizana kwa Lactose.

Tcherani mosamala kwambiri!

Mankhwala "Koraksan" (mtengo, zifaniziro za mankhwalawa zidzafotokozedwa m'munsimu) ziyenera kugwiritsidwa ntchito kokha kwa mankhwala a dokotala. Modziletsa kwambiri, mapiritsi awa ayenera kutengedwa ndi:

• Kulephera kusamala (mwaulemu amatchulidwa);
• Kukhazikika kwa nthawi ya QT (yobadwa);
• Kulephera kwachinyengo (kovuta);
• Kugwiritsira ntchito mankhwala osokoneza bongo omwe amapititsa nthawi ya QT;
• Kugwiritsira ntchito madzi amtundu wa palimodzi panthawi imodzi komanso mavitamini a cytochrome isoenzymes;
• Kusokonezeka kwamtundu wa ventricle wamanzere;
• Atrioventricular blockade ya digiri ya 2;
• Sitiroko (yasinthidwa posachedwa);
• Mitundu ya retinal (kutaya kwake);
• Kusokoneza;
• Kusamalidwa panthawi imodzimodziyo kwa anthu oteteza calcium channel (mwachitsanzo, Diltiazem kapena Verapamil).

Kukonzekera "Koraksan": malangizo othandizira

Mafotokozedwe a mankhwalawa amasonyeza njira zofanana zogwiritsa ntchito ndi mlingo monga mankhwala omwe amatchulidwa. Koma musanawagwiritse ntchito, muyenera kuwerenga malemba omwewo ndipo mufunseni dokotala wanu.

• Ndi angina yolimba, mankhwalawa mu mlingo woyambirira amauzidwa kuchuluka kwa 10 mg patsiku. Ngati patapita masabata 3-4 chithandizo cha mankhwala chisanafike, mlingo wa tsiku ndi tsiku uyenera kuwonjezeka kufika 15 mg pa tsiku.
• Mu kulephera mtima kwa mtima, mankhwala oterewa pa mlingo woyambirira amauzidwa kuchuluka kwa 10 mg pa tsiku. Ngati patapita milungu iwiri mankhwala asanafike, mlingo wa tsiku ndi tsiku uyenera kuwonjezeka kufika 15 mg pa tsiku.
• Kwa odwala omwe ali ndi zaka 75, mlingo woyamba woyenera ndi 2.5 mg kawiri pa tsiku. M'tsogolomu, mukhoza kuwonjezera mlingo wa mankhwala.
• Chifukwa cha kuphwanya kwa impso, odwala amapatsidwa mankhwala "Koraksan" pa kuchuluka kwa 10 mg patsiku. Ngati patapita masabata 3-4 chithandizo cha mankhwala chisanafike, mlingo wa tsiku ndi tsiku uyenera kuwonjezeka kufika 15 mg pa tsiku.
• Ngati kuwonongedwa kwa chiwindi, odwala amapatsidwa mankhwala "Koraksan" pa kuchuluka kwa 10 mg patsiku. Ngati patapita masabata 3-4 chithandizo cha mankhwala chisanafike, mlingo wa tsiku ndi tsiku uyenera kuwonjezeka kufika 15 mg pa tsiku.

Zotsatira zotheka mutatha kumwa mankhwala

Ngakhale kuti zili bwino, sikuti munthu aliyense amene ali ndi vuto la mtima amathamangira kumwa mankhwalawa. Choyamba, izi ndi chifukwa chakuti ali ndi zotsatira zambiri:

• Masomphenya osasintha ndi kusintha kawirikawiri kumvetsa kuwala (kapena otchedwa photopsy).
• Bradycardia, sinus arrhythmia, ventricular extrasystole, angina (osasunthika), palpitations, myocardial infarction, arterial hypotension, katemera wambiri, mankhwala oopsa, tricycardia ya ventricular ndi myocardial ischemia.
• Kutsekula m'mimba, kunyoza ndi kudzimbidwa.
• Mutu (makamaka m'mwezi woyamba wa chithandizo), chizunguliro, kupuma pang'ono, minofu ya minofu, kutsekemera ndi kutaya.
• Hyperuricemia ndi eosinophilia.
• Kuthamanga kwa khungu, angioedema, kuyabwa, urticaria ndi erythema.
• Asthenia, malaise ndi kutopa.

Mankhwalawa "Koraksan": ndemanga, mafananidwe a mankhwala

Amene agwiritsira ntchito chida ichi mobwerezabwereza, kambiranani bwino. Komabe, mankhwala ngati amenewa ndi okwera mtengo kwambiri. Kotero, pa mapiritsi 56 a mankhwala "Coraxan" mudzayenera kulipira pafupifupi 1200 Russian ruble. Pankhaniyi, odwala ambiri omwe ali ndi matenda a mtima nthawi zambiri anayamba kugula zizindikiro zosakwera za mankhwala.

Mankhwala otsatirawa angathe kusankhidwa ngati mafananidwe amtundu wa wothandizira awa:

• Ivabradine hydrochloride;
• Iwabradine.

Malingana ndi zotsatira zowonongeka (zokonzekera za mankhwala a angina pectoris):

• Amlodipine;
• Asparks;
• Atenolol;
• "Aspirin Cardio";
• Betalok;
• "Validol";
• Onetsetsani;
• "Isoket";
• Diltiazem;
• "Isolong";
• Chithunzi;
• Chithandizo;
• "Corvitol";
• Lokren;
• "Cordipin";
• Kalata ya Corinthard;
• Metoprolol;
• Kusakaniza;
• "Monosan";
• "Nitroglycerin";
• "Papaverin";
• "Nayitrogeni";
• "Nifedipine";
• "Sinthani";
• "Plavix";
• "Prestans";
• Msewu;
• "Sustonite";
• "Trimetazidine";
• "Tenox";
• "Egilok";
• "Efoks Long" ndi ena.