Mankhwala "caver": malangizo ntchito (jakisoni)

Ngati inu kuchotsa ululu zakayendesedwe ka m'kamwa mankhwala sizingatheke ntchito "caver" jekeseni. Kagwiritsidwe Guide akuonetsa jakisoni kuchita pamene ululu syndrome sing'anga ndi mkulu mwamphamvu. Izi zikhoza kukhala chikhalidwe postoperative wodwalayo, colic aimpso ndi ululu otsika kumbuyo.

The zikuchokera ndi maonekedwe za kumasulidwa mankhwala

Mu 1 ml ya yothetsera jekeseni ndi 25 mg wa yogwira pophika - dexketoprofen. The zosakaniza wothandiza monga Mowa thunthu mu kuchuluka kwa sodium kolorayidi 96%, hydroxide ndi sodium ndi madzi a jekeseni.

kukonzekera ndi bwino colorless madzi. Mmatumba mu mbale galasi, amene akachita mukatoni ndalama 5-10. Aliyense vial lili 2 ml ya "caver" mankhwala.

Malangizo ntchito jakisoni anafotokoza kuti sanali steroidal antiinflammatory ndi antirheumatic wothandizila ena ofanana asidi propionic.

katundu pharmacological

Dexketoprofen trometamol (yogwira mankhwala lokonzekera) ndi mchere asidi propionic. Yodziwika analgesic, antipyretic ndi katundu odana ndi yotupa. Adzaupereka kwa gulu la anthu omwe sanali steroidal mankhwala odana ndi yotupa, kapena NSAIDs.

Limagwirira ntchito umalimbana kuchepetsa kaphatikizidwe prostaglandins chifukwa chopinga wa cyclooxygenase. Ndiko kuti, liwiro kutembenuka asidi arachidonic mu endoperoxides PGG2 ndi PGH2 cyclical chikhalidwe. Awa, nayenso, anapanga prostaglandins PGEi, PGE2, PGF2a, PGD2, kuphatikizapo zinthu monga prostacyclin PGI2, thromboxane ndi ThAg ndi ThVg. Yimitsira wa prostaglandin kaphatikizidwe amakhudza nyemba za ndondomeko yotupa, monga kinins, zokhudza ntchito yaikulu ya medicament lapansi. Dexketoprofen anaulula zotsatira ochepetsera pa ntchito Cox-1, Cox-2.

Mayesero matenda anakhazikitsa zotsatira analgesic ya mankhwala mu amawasonyeza mosiyanasiyana ululu. Tidapeza mankhwala ochititsa ake katundu mwa kuyambitsa mu njira jekeseni. Analysis kunachitidwa pa zotsatira za ululu mu nthawi postoperative za phukusi. Izi mafupa ndi matenda popanga munthu opaleshoni, komanso opaleshoni m'mimba. Ntchito pa amawasonyeza mosiyanasiyana kwa kupweteka kwa msana mankhwala "caver". Malangizo ntchito jakisoni amalimbikitsa kuchita ndi colic aimpso.

Kafukufuku wasonyeza kuti malo zachipatala amachita nthawi yomweyo, ndi dzuwa ake pazipita akuwonetseredwa pa mphindi makumi asanu. Analgesic zotsatira pa chamoyo amatenga pafupi eyiti maola, koma pansi chikhalidwe chimene wakhala anayambitsa osachepera 50 mg amatanthauza "caver" (jekeseni). Kufotokozera mwa zizindikiro kwa mankhwala - zonse ziri zofunika kwambiri kuphunzira patsogolo ntchito.

Ndi utsogoleli mu mnofu wa dexketoprofen trometamol ndende apamwamba anati mu maminiti makumi awiri. Pawiri ali ndi digiri yapamwamba magazi mapuloteni plasma wa - 99%. Wofalitsa dexketoprofen fluctuates padziko 0,25 L / kg. poluraspredeleniya nthawi ya maola 0,35. Anasonyeza pambuyo maola 1-2,7.

Zikuonetsa ntchito mankhwala

Izo ziyenera kuperekedwa intramuscularly kapena m'nsinga ululu pachimake matenda, sing'anga ndi mkulu mankhwala "caver" mwamphamvu. Malangizo pa ntchito jakisoni analangiza kuchita kokha pamene mankhwala m'kamwa sukukuthandizani. Iwo ayenera kumwedwa mutamaliza opaleshoni, ngati colic aimpso, ndi ululu m'dera lumbar.

contraindications

Iwo ali mankhwala "caver" (akatemera) zizindikiro ndi contraindications. Gulu lachiwiri monga:

• hypersensitivity kwa yogwira mankhwala deksketoprofenu ndi mbali zina za njira;
• kuukira mphumu spasms bronchial;
• pachimake rhinitis, tizilombo ting'onoting'ono m'mphuno, urticaria, angioneurotic edema;
• zilonda ndi magazi;
• m'mimba magazi ;
• Amatupitsa matenda kapena anam'peza matenda a m'matumbo;
• mbiriyakale ya mphumu bronchial;
• mtima kulephera;
• matenda aimpso sekondale ku chaukali;
• ndi magazi matenda;
• aakulu kwa chiwindi matenda;
• Ntchito neuraxial (intrathecal kapena epidural) Dongosolo;
• pregnancy, makamaka III trimester;
• mkaka wa m'mawere.

Sikuti kulekeza aliyense wa mfundozi poika "caver" (akatemera) mankhwala. Malangizo ntchito limafotokoza mbali zonse za ntchito yoyenera ya mankhwala.

mankhwala si kutumikiridwa odwala chifukwa kuda ka amadza chifukwa cha thupi la mwanayo. CHENJEZO azitenga ndi okalamba.

Mankhwala "caver" (jakisoni): malangizo ntchito

Kwa achikulire, mlingo ali 50 mg utsogoleli. The imeneyi pakati jekeseni ayenera kukhala maola 8-12. Ngati ndi kotheka, jekeseni chachiwiri ikuchitika pambuyo maola asanu. Mlingo tsiku ndi 150 mg. Mankhwala ntchito mpumulo mwa nthawi ya ululu waukulu. Si ntchito masiku opitirira awiri mu mzere. Pambuyo mankhwala koyamba ululu, ngati zinthu amalola, wodwalayo ndi kunditumiza ku dzanzi m'kamwa.

mavuto pa thupi ndi kuchepetsa osachepera analola mlingo utsogoleli. Pambuyo pa opaleshoni kuti zomverera ululu amphamvu ndi pafupifupi madigiri a kuopsa kwa mankhwala ntchito mosamalitsa anasonyeza. ngakhale nkotheka mankhwala ndi analgesics opioid.

Okalamba musati kusintha mlingo. Koma ngati njira kagayidwe kachakudya mu impso m'mbuyo ali wamkulu akadali osavomerezeka kuchepetsa mlingo. The lololedwa mlingo ndi pang'ono chintchito impso ndi 50 mg.

Odwala matenda a chiwindi (5-9 mfundo pa Child-Pugh) mlingo tsiku kusanduka 50 mg. Pambuyo utsogoleli wa mankhwala mu thupi mosamala kuwunika ntchito ya thupi ili. Mu kwambiri matenda gawo chiwindi mankhwala si kutumikiridwa (10-15 mfundo pa Child-Pugh).

Mu matenda wofatsa, aimpso (creatinine chilolezo -. 50-80 ml ya / Mph) tsiku mlingo sayenera upambana 50 mg. Ngati zolimbitsa kwambiri kapena kukanika aimpso, imene creatinine chilolezo cha <50 mL / Mph, mankhwala ndi koletsedwa.

Jekeseni chikuyendetsedwera ngati njirazo mu mnofu ndi mtsempha. Pamene kutumikiridwa mwai intramuscularly pang'onopang'ono kwambiri moti "caver" (jekeseni).

Monga kukonzekera mbewu kwa kulowetsedwa mtsempha

The madzi mu ampoule 2 ml pa makonzedwe mu mtsempha ayenera kuchepetsedwa. Kuti zili ampoule n'kofunika kuwonjezera 30-100 ml ya sodium kolorayidi 0,9%, shuga kapena lactate njira Ringer a. The madzi a jekeseni mtsempha linakonzedwa pansi wosabala. Thunthu okonzeka ayenera mandala kwathunthu ndipo alibe zosafunika. Kulowetsedwa imagwiridwa kwa mphindi khumi ndi makumi atatu. Kodi Sangaonetsere poyera kuti tsiku dzuwa udzathetsa pa kukonzekera, ndi pa jekeseni.

"Caver" (jekeseni mu ampoules) Buku akuonetsa kuti limodzi ndi mankhwala kawetedwe. Pakuti ichi 2 ml ampoule ayenera kuwonjezera 100 ml ya sodium kolorayidi 0,9%. Nthawi zina mankhwala akhoza kuchepetsedwa ndi shuga mu chiŵerengero chomwecho.

Iwo ndikoletsedwa kuphatikiza mu njira jekeseni "Promethazine" ndi "Pentazocine" ndi medicament "caver" (jekeseni).

Kodi ntchito mankhwala bolus? Kuti zimenezi zitheke, ndi kulowetsedwa njira buku la 2 ml si kuchepetsedwa. Thirani msanga, masekondi khumi. Iyi ndi nthawi ya utsogoleli sayenera yafupika. Kuphatikiza Mlingo otsika analoleza "caver" zakumwa m'jekeseni monga "Heparin", "lidocaine wa", "Morphine" ndi "theophylline".

Sikuti kusakaniza jekeseni madzimadzi ndi yaing'ono mlingo "dopamine", "Promethazine", "pentazocine", "pethidine" ndi "Hydrocortisone". Ndi bwino chifukwa chiopsezo cha precipitate woyera, umene ndi osafunika kwambiri pa ndondomeko.

Mankhwala sayenera ngakhale yachiwiri patsogolo yosungirako ndipo ayenera kuperekedwa nthawi yomweyo pambuyo Kutolere ndi ampoule galasi. Njira yothetsera ayenera kugwiritsidwa ntchito yomweyo pambuyo kusakanikirana mankhwala zonse zofunikira. Udindo kulondola wochita imagwera chala ntchito thanzi.

Jekeseni pambuyo kuphika lofotokozabe katundu onse liziyenda bwino masana. chikhalidwe ichi ndi kukhuta ngati mankhwala okonzeka kwathunthu kutetezedwa masana ndi kutentha zinthu osati choposa 25 ° C.

Ampoule "caver" lakonzedwa jekeseni imodzi. Zatsalira njira yomweyo zobwezerezedwanso. Asanalankhule kulowetsedwa, ndi kuonetsetsa kuti njira chimaonekera ndipo alibe kudetsa mtundu. Ngati mankhwala ena aliwonse particulate kanthu sangathe ntchito.

Zotsatira zoyipa za mankhwala

zingapo mavuto pambuyo kumayambiriro "caver" (akatemera) mankhwala zingaoneke. Malangizo zikuphatikizapo zomwe kawirikawiri amaoneka zochitika monga kunyansidwa ndi kusanza. Pali ululu jekeseni malo, kutaya magazi, kutupa ndi hematoma. Nthawi zina zikuoneka magazi m'thupi, kusowa tulo, chizungulire, tulo ndi mutu. Kawirikawiri atathana malungo komanso kutopa, amaona masomphenya, kuzizira. Panali ululu m'mimba, dyspepsia. Pambuyo jekeseni nthawi zina akutsegula m'mimba kapena kudzimbidwa, kusanza magazi. kwambiri dryness mkamwa anazindikira. Odwala ena ali dermatitis nkhawa, kuyabwa, totupa thukuta kwambiri.

Nthawi zina, pali hyperglycemia, hypertriglyceridemia ndi matenda a anorexia. Paresthesia nawonekera atakomoka. Kutanganidwa odwala tinnitus, kumenyedwa msanga ndi tachycardia. Nthawi zina, zizindikiro za matenda oopsa, thrombophlebitis, bradypnea ankalembedwa. Panali zilonda, matenda a chikasu ndiyo, totupa, ziphuphu nkhawa, minofu stiffness, olowa stiffness. Maonekedwe a omangana minofu ululu kumbuyo. Pang'ono ananena kuchuluka mkodzo mapangidwe, aimpso colic, acetonuria. Panali zolephera kuzungulira kusamba ndi kugwira ntchito kwa prostate. Panali kugwedeza minofu, edema zotumphukira.

Nthawi yapadera izo unkachitika odwala neutropenia ndi thrombocytopenia. Zitsanzo munthu amasonyeza zochita anaphylactic, mwachitsanzo, anaphylaxis. kawirikawiri kuwonetseredwa bronchospasm, dyspnea. Kusokoneza nthawi zina kapamba ndi matenda Stevens-Johnson, epidermal necrolysis. Odwala zowawa pambuyo ka jekeseni wa angioedema, nkhope edema, photosensitivity. Umboni kwa wina ndi zikwi khumi mu nkhani ya nephritis matenda ndi matenda nephrotic.

Mwalamulo mfundo cha mankhwala osokoneza bongo akhala sakudziwika. Pamene choposa cha Mlingo analimbikitsa wa medicament limakhudza anthu thirakiti m'mimba, kuchititsa kusanza, kupweteka m'mimba, ndi matenda a anorexia. Akhoza kuoneka kugona ndi disorientation, chizungulire, mutu. Kudziwa mfundo ambiri osokoneza ayenera yomweyo zinthu zina ndipo amafuna mankhwala kwa chamoyo ndi dialysis.

analogues mankhwala

Mtengo wa mankhwala losiyana "caver" (jekeseni). Analogs za mankhwala angapezeke mu mankhwala aliwonse. ATC malamulo omwewo ndi yogwira chigawo mankhwala zotsatirazi:

• "Alfort Dex."
• "Dekafen".
• "Delsangin".
• "Delsangin Inekt"
• "Depiofen".
• "Rastel."
• "Sertofen".

Mankhwalawa angathe kwathunthu m'malo "caver" (akatemera), ngati kuli kofunika. Analogs ndipo mmalo mwa kuchita mankhwala N'chimodzimodzinso ndi kukhala chimodzimodzi yogwira mankhwala, mbwenye nkhabe kukatenga paokha. Pamaso kuchotsa munthu mankhwala wina ayenera kuonana ndi dokotala amene angakuthandizeni kusankha njira yabwino kwambiri.

Mtengo wa mankhwala

Anapanga mu Ukraine mankhwala "caver" (akatemera). Buku akuonetsa ntchito si nthawi zonse, koma apo, ndi masiku opitirira awiri. Mu Russia, mankhwala si ambiri ndipo si chogulitsidwa pharmacies, kotero inu mukhoza kuitana mtengo idzatha. Inakhalapo yomasulira ku hryvnia kwa ruble Russian, kutenga nkhani nduna kusinthitsa ndalama limene panopa 1 UAH. wolingana 3,21 rubles. Mu Ukraine, izi mankhwala akhoza kugulidwa kwa 200 hryvnia. Kumbali ya mtengo adzakhala wofanana 640 rubles Russian.

The njira yosungirako ndi alumali moyo

Musaphwanye kusunga kuposa zaka ziwiri pa nthawi kupanga izikhala pa ma CD, mankhwala "caver" (akatemera). Kufotokozera za mankhwala ananena kuti pamapeto pa alumali moyo wa mankhwala si abwino ntchito. Kusunga zikutanthauza zofunika mu bokosi wapachiyambi pa kutentha osati choposa 25 ° C. Mankhwala ayenera kukhala pa malo ozizira kuwerengedwa ana ndi kutetezeredwa dzuwa.

Amagulitsidwa drugstores mosamalitsa pa mankhwala. Mlengi ndi Chiyukireniya kampani PJSC "Farmak".

"Cavers" - wodalirika komanso kwambiri ogwira dlyakupirovaniya pachimake ululu. Zokha ntchito yochepa. Zikuoneka pa msika ndi posachedwapa ndi sanabadwe adakwanitsa kupambana kwa ogula malo. Izo zikhoza kugulidwa mwa pharmacies online, komanso kudzera pharmacies akuluakulu a m'mizinda ikuluikulu ya Ukraine.