Streptomycin kwa zinyama: malangizo ogwiritsira ntchito, kufotokozera ndi ndemanga

Kodi ndi zochuluka bwanji komanso kuchokera ku zomwe zikuwonetseratu mankhwalawa monga "Streptomycin"? Malangizo ogwiritsiridwa ntchito, mtengo ndi cholinga cha mankhwalawa zidzakambidwa pansipa.

Fomu, kufotokoza za mankhwala owona zanyama

Mankhwalawa "Streptomycin sulfate" (Chowona Zanyama) ndi mchere wambiri, womwe umapangidwa ndi bowa lamoto kwambiri.

Pogulitsa mankhwalawa amabwera ngati mawonekedwe a ufa wochuluka kapena mtundu wambiri wa mtundu woyera, kulawa kowawa, kopanda fungo komanso mosavuta mumadzi, novocaine ndi saline.

"Streptomycin" ya mankhwala amachiritso amagwiritsidwa ntchito nthawi zonse. Tiyeneranso kukumbukira kuti imakhala yosasunthika mu sing'anga yochepa kwambiri, koma imatha kusokoneza bwino mankhwala a alkali (ndi Kutentha) ndi zida zamphamvu.

Pharmacology ya mankhwala

Kodi mankhwalawa "Streptomycin" amagwira ntchito bwanji zinyama? Malangizo a zolemba zomwe amagwiritsa ntchito kuti wothandizirayu ali ndi mabakiteriya ndi mabakiteriostatic motsutsana ndi mabakiteriya ambiri a gram-negative ndi gram-positive.

Kugwiritsa ntchito mankhwala osokoneza bongo chifukwa cha mphamvu zake zopezera mapuloteni m'maselo ang'onoting'ono omwe ali pamtingo wa ribosomes. Tiyeneranso kukumbukira kuti mankhwalawa alibe mphamvu pa matenda amene Clostridia ndi ena anaerobic tizilombo toyambitsa matenda, bowa, plasmodia, mavairasi ndi rickettsia. Komanso, tizilombo timene timasonyeza kuti tikutsutsana kwambiri ndi streptomycin, ndipo pakubereka kusakaniza kwa mabakiteriya kumachitika masiku angapo. Pa nthawi imodzimodziyo, mitsempha yambiri yolimbana imayamba kumapeto kwa mwezi wachiwiri wa mankhwala. Kuti muteteze izi ndi kuthetsa matendawa, muyenera kugwiritsa ntchito mlingo waukulu wa mankhwalawa, komanso kuzilumikiza ndi othandizira ena.

Pharmacokinetic zizindikiro za mankhwala

Kodi mankhwalawa "Streptomycin" amatenga zinyama? Malangizo ogwiritsira ntchito amanena kuti pamene akugwiritsidwa ntchito pamlomo saloledwa ndi kuchotsedwa kwathunthu m'matumbo.

Ndi jekeseni wa m'mimba, mankhwala othandiza a mankhwalawa amayamba kulowa m'magazi, ndipo amapezekanso ndi phokoso ndi piritoneal cavities, bile, vitreous humor, mkodzo ndi maso.

Mu njira zopweteketsa kwambiri pamapemphero okhutira, ma antibiotic akhoza kufika pafupifupi 50 peresenti ya mlingo wa magazi.

Ndi chitukuko cha meningitis streptomycin amatha kulowa mu ngalande ya msana pamtundu wa 10-50%.

Wogwiritsira ntchito mosavuta amadutsa pamtunda. Ndi chizoloŵezi chachiwindi chogwira ntchito, streptomycin imakhala m'magulu akuluakulu. Ndi ntchito yogwedezeka ya chiwalo ichi, imalowa mkati mwa bile pang'ono, ndipo ndi cholecystitis zomwe zili mu ndulu yamkamwa ndi pafupifupi 85% mwa magazi.

Mitsempha yotchedwa streptomycin yothandizira m'magulu osiyanasiyana ndi ziwalo zimagwiritsidwa ntchito kwa maola 8-13. Thupili limachotsedwa msanga kuchokera ku thupi ndi mkodzo.

Zizindikiro zogwiritsa ntchito mankhwalawa

Ndi matenda ati omwe amachiritsidwa ndi mankhwala mu funso? Kodi malangizo oti agwiritse ntchito mankhwalawa akunena chiyani izi? "Streptomycin sulfate" yalembedwa:

• Ndi leptospirosis, tularemia, chibayo;
• Matenda owopsa a nkhumba ndi erysipelas, malungo a catarr (malungo);
• Matenda a diplococcal, mastitis, endometritis;
• Endocarditis, meningitis, postpartum ndi chilonda sepsis;
• Actinomycosis ya ng'ombe ndi campylobacteriosis, komanso matenda ena, omwe amachititsa chidwi kwambiri streptomycin.

Zomwe zingagwiritsidwe ntchito

Ndi liti pamene simuyenera kupereka mankhwala "Streptomycin" kwa zinyama? Malangizo ogwiritsidwa ntchito, ophatikizidwa ndi mankhwala, asonyeze zotsutsana izi:

• Kuteteza kwambiri kwa nyama kupita ku aminoglycoside antibiotics;
• Kukhalapo kwa mtima wamtima ndi kulephera kwa mphuno.

Tiyeneranso kukumbukira kuti mankhwalawa sangathe kuphatikizidwa ndi othandizira aminoglycoside (kuphatikizapo "Neomycin," Kanamycin, "Monomycin," Gentamycin ") chifukwa cha kukula kwa nephrotoxic.

Malangizo a mankhwala "Streptomycin Sulfate" (kuti agwiritsidwe ntchito pa zinyama)

Musanagwiritse ntchito wothandizirayo, imasungunuka mu thupi lachilengedwe, madzi osabisa kapena 0.25-0.5% yankho la novocaine. Chiŵerengero chotsatirachi chikutsatiridwa: 0.25 g wa streptomycin ndi 1 ml ya zosungunulira. Mwa njira, njira yothetsera shuga monga yotsiriza imaletsedwa.

Zambiri zowonjezera zingakhale zopweteka kwambiri. Njira yothetsera imatha kusungidwa kutentha kwa mlungu umodzi (ndi bwino kuisunga mu firiji).

Kodi ndingagwiritse ntchito bwanji Streptomycin kwa zinyama? Malangizo ogwiritsira ntchito akuti njira yothetsera yokonzekera ikhoza kugwiritsidwa ntchito mosagwiritsidwa ntchito, mwachangu, kunja, pamlomo, m'kati mwa thupi, m'matumbo, m'katikatikati, mu intrauterine komanso mopanda ntchito.

Jekeseni ya m'mimba ya nyama imakhala mkati mwa minofu. Mankhwalawa amaperekedwa kwa masiku 4-7. Mankhwalawa amathandizidwa kawiri patsiku pakati pa maola khumi ndi awiri muzilingo zotsatirazi:

• Ng'ombe zazing'ono - 10 mg / kg kwa akuluakulu ndi 20 mg / kg kwa zinyama;
• Mahatchi - 5 mg / kg nyama zazikulu ndi achinyamata 10 mg / kg;
• Ng'ombe zazikulu - 5 mg / kg kwa akuluakulu ndi 10 mg / kg kwa achinyamata;
• Agalu, nkhumba - 10 mg / makilogalamu akuluakulu ndi 20 mg / kg kwa zinyama;
• Nkhuku - 30 mg / kg kwa akuluakulu ndi 40 mg / kg kwa achinyamata.

Ndi leptospirosis, mankhwalawa "Streptomycin" amaperekedwa kwa masiku 4-10 pa mlingo wa 25 mg / kg. Pa milandu yovuta kwambiri, ndalamayi ikuwonjezeka.

Tiyeneranso kukumbukira kuti, ngati n'koyenera, mankhwalawa akuphatikizidwa ndi "Polymyxin", "Penicillin" ndi mankhwala a sulfonamide. Kuphatikiza kwa mankhwalawa kumayambitsa kugwirizana kwa zochita, komanso kumapangitsa kuti tizilombo toyambitsa matenda tizilombo tizilombo toyambitsa matenda tiyambe ku streptomycin.

Zovuta zochitika

Tsopano mukudziwa chomwe mankhwalawa "Streptomycin Sulfate" ali. Malangizo ogwiritsiridwa ntchito kwa nyama adanenedwa pamwambapa.

Ndi jekeseni ya m'mimba, kutuluka mofulumira kwazitsamba kungadziwonetsere ku ziweto , zomwe zimawopsyeza thanzi ndi moyo wa chinyama. Kupezeka kwa mavuto ngati amenewa kumakhudzana ndi maonekedwe a thupi lake ndipo sikudalira mankhwala omwe amagwiritsidwa ntchito.

Komanso, mavuto osiyanasiyana angathe kukhalapo pambuyo poyambitsidwa kachitidwe ka mankhwala, komwe kawirikawiri imayambitsidwa ndi kuyambitsa chinyama pakapita nthawi.

Pomwe mukuchiza mankhwalawa mu ziweto mungaone zotsatira zowopsa, kutsegula m'mimba, tachycardia, dermatitis, kumva wogontha komanso kulephera kugwirizana.

Mtengo ndi Kuyankha

Mtengo wa mankhwala mu funso (1 g botolo) ndi pafupifupi 18 ruble.

Akatswiri ena samalangiza kusakaniza "Streptomycin Sulfate" ndi "Penicillin" mu syringe imodzi. Komabe, akatswiri ena a zinyama amagwiritsira ntchito ntchitoyi pothandizira ziweto.

Anthu omwe akukumana ndi mankhwala owona Zanyama zambiri kwa nthawi yaitali amanena kuti kulankhulana koteroko kumawachititsa kuti akhale ndi dermatitis.

Malingana ndi akatswiri, kupha nyama zomwe zinkaperekedwa "Streptomycin" kumaloledwa sabata imodzi yokha atatha kugwiritsa ntchito mankhwalawa. Nyama ya nyama yomwe inaphedwa isanafike nthawi yomaliza iyenera kugwiritsidwa ntchito popanga ufa.

Ponena za mkaka, chifukwa cha chakudya chingagwiritsidwe ntchito patangotha masiku awiri mutatha kulamulira mankhwalawa.