Mukutanthauza chiyani, "matendawa RNA wapezeka"? Analysis wa matendawa RNA

Matenda a chiwindi C mungathe lililonse. Anthu ambiri amakhala ndi matenda kwa zaka osati ngakhale kuti iwo unayambitsidwa mu limagwirira kuti posapita nthawi kuyambitsa mavuto aakulu. Anthu otero mwachangu kupatsira ena, ndi mlingo wa zochitika ndi mosalekeza kuwonjezeka. Kuchepetsa Chiwerengerochi, munthu ayenera kukhala ndi ulamuliro chokuchititsani kusanthula nthawi kwa chiwindi C, makamaka ngati ali pangozi.

mudziwe mwachidule za matendawa

Chiwindi C HIV (matendawa) RNA molekyulu limapangidwa onyamula mudziwe majini ndi mapuloteni wapadera umene kucheza ndi thupi la munthu. Opatsirana pogonana makamaka mwa mwazi ndi. Nthawi zina, nkotheka ofukula HIV (T. E. mayi mwana).

Ozama mu thupi, izo zikukhazikitsa maselo osiyanasiyana magazi (neutrophils, monocytes, lymphocytes) ndi chiwindi (hepatocytes).

matenda chinyengo ndi yonena za zizindikiro za gawo pachimake. Nthawi yomweyo amakhala aakulu asymptomatic ndi wosakwiya amasonyezera mphamvu zake zowononga.

zotsatira

Kuyambira pachiyambi cha malowedwe mu thupi la matendawa RNA pamaso zizindikiro choyamba akhoza kutenga zaka zambiri, nthawi zina kwa zaka 15-20 kapena zambiri. Zikamera madandaulo lililonse kwa mitundu zapamwamba za matenda C, pamene chiwindi kale kwambiri anakhudzidwa. Ambiri odwala awa amapezeka zotsatirazi matenda chiwindi:

• matenda enaake;
• necrosis;
• chosaopsa cysts;
• Oncology.

Isanafike chitukuko cha mavuto wodwala angaone indisposition pang'ono, zomwe kawirikawiri sakhala ngofunika.

Kuchita kuwunika

Analysis wa matendawa RNA lomwe kuti anthu amene ali sitichedwa matenda. Mu gulu limeneli ndi:

• osokoneza;
• anthu zachiwerewere;
• onse amene amachita zochita kugonana mosadziteteza, makamaka ndi bwenzi latsopano;
• mafani mphini, kuboola, kukongola salons (hairdressers);
• anthu amene akukonza ndondomeko opaleshoni (kuphatikizapo kumene, matenda mano);
• Anabadwa pasanafike 1990, amayi ya ana (chakuti pa nthawi matenda silinakwaniritsidwe amadziŵika, kotero kuikidwa akazi awa nako kachilombo);
• Ana ndi amayi;
• achibale ndi ogonana kwa kachilombo;
• Odwala aakulu chiwindi matenda a chikhalidwe osadziwika.

Mndandanda ndi yaikulu kwambiri, ochepa amene anganene motsimikiza kuti chiopsezo wake wa matenda ndi ziro.

kuyezetsa kunyumba

Angati akanafuna kuti aone mtima wa matendawa RNA, koma osati kupita dokotala chifukwa cha manyazi, kusowa nthawi sakonda zipatala ndi zina zotero. N.

Kodi kuthandiza kuthetsa matenda yosavuta kugwiritsa ntchito yapadera mofulumira zofufuza (Elisa). Pankhaniyi, njira Mkhalidwe amasankha yekha mfundo ya kukhalapo kwa chitetezo ku HIV.

Mozama pa mfundo za mayeso kwa mimba, koma ngati magazi mayeso chuma chofunika:

1. Complete ndi Mzere pulasitiki (polojekiti kwa kuwunika) ndi Lancet wapadera, kuboola chala pa zowawa za batani.
2. Ndi mbali ya magazi pipette aikidwa mu chipinda chapadera, ndipo patapita mphindi 10-15 kupenda ayankhe.
3. mipiringidzo ziwiri zikuonetsa zabwino, wina - pa negative. Wotumbululuka maonekedwe a malo chachiwiri mu zoni mayeso akusonyeza pamaso pa matenda Komabe, anthu ambiri zimawatengera m'magazi ndi otsika kwambiri.

Ngati matenda wakhala kuzindikiridwa, m'pofunika kupita kwa adotolo kupenda.

Zoyamba za kudziwika matendawa RNA

Ndi zotsatira m'pofunika kutembenukira kwa matenda opatsirana ndi hepatology, amene adzamuika kuunikidwa zina.

Chinthu chachikulu kuchita kusanthula zina - kudziwa kumene genotype monga atulukira chiwindi, ndi kudziwa kuchuluka kwake m'magazi. Kuchokera deta analandira kudzadalira mankhwala zina, kuyambira mitundu yonse amasiyana mzake ndi angalankhule mosiyana mankhwala. Komanso, tizilombo amatha mwaluso masked.

mitundu ya kafukufuku

Mu matenda a matendawa ntchito imodzi mwa njira zotsatirazi:

1. PCR. Pankhaniyi tikulankhula za zinthu majini a tizilomboto lapansi.
2. Kachulukidwe kusanthula matendawa RNA (r Mukhoza-DNK, TMA). Chotero kusanthula ndi ikuchitika pambuyo chitsimikiziro cha kukhalapo kwa tizilomboto mu thupi. Limatchedwanso katundu tizilombo. Timatha kuzindikira chiwerengero cha oimira tizilombo mu 1 ml magazi. Kuyambira zolozerazi izo zimatengera nthawi ya mankhwala ndi digiri ya infectiousness wodwala. R-DNK amachita mayeso osiyanasiyana pa 500 INE, ndi TMA pa 5-10 INE. njira onse amaonedwa kukhala yosavuta ndi wotsika mtengo.
3. Genotyping. Iwo anachita otsiriza ndipo amalola mwachindunji kumene mitundu monga akudzizindikiritsa matenda.

Lowunikira la zotsatira

Ngati kusanthula matendawa RNA anali wotsimikiza ndi PCR ndi Elisa, matenda zikutsimikiziridwa. Komabe, chifukwa zoipa sapereka chitsimikizo cha pakalibe matenda. Mwatsoka, izo zimachitika nthawi zambiri chifukwa ndondomeko angagwiritsidwe ntchito reactants ndi kudana ndi osiyana.

Anthu ambiri amadabwa chomwe chimatanthauza, "matendawa RNA wapezeka". Umboni umenewu kwenikweni amasonyeza pakalibe matenda kapena ndende zake otsika. Mwachitsanzo, PCR 200 INE / ml zotsatira zabodza ngati wodwalayo chiwerengero cha magazini tizilombo pang'ono. Izi zikhoza kuchitika pamene matenda posachedwapa kapena pa mankhwala.

Kawirikawiri wodwala safuna kuti likhale mfundo zimenezi, kuyambira mfundo zimenezi ziyenera chifukwa ndi dokotala nawo.

Kudziwika matendawa RNA kafukufuku kachulukidwe pa 400 000 INE ndi zambiri amanena kuti kachilombo palibe yekha mu magazi, komanso mwachangu zimafalitsidwa, motero matenda ena. Ngati index ali pafupi 800 000, izo zimasonyeza kuti pali gawo pachimake ndi yogwira maselo chiwindi matenda.

Ngakhale pali katswiri maganizo mogwirizana. Ena mwa iwo amati ubale ndi liwiro Kukula kwa matendawa ndiponso chiwerengero cha magazini a HIV kumeneko.

odwala amenewa ayenera kusamala makamaka kulankhulana ndi okondedwa awo.

zofufuza zina

Pambuyo kudziŵa matendawa RNA ndi maphunziro ena awerenge wodwala chikukhudza:

• kudziwika chiwindi B;
• ambiri kusanthula magazi ndi mkodzo;
• sayansi;
• Ultrasound wa pamimba;
• Kujambula kapena CT mapanga sikani a chiwindi (anasonyeza).

Atalandira zonse zofunika dokotala amayang'anitsitsa zotsatira, udindo thanzi wodwalayo, kenako amasankha chithandizo munthu chiwembu iye.

Pamene yake kudziwika kuwonongeka kwa chiwindi, kawirikawiri kwina.

Achire njira ndi nthawi

Kutalika kwa nthawi yoperekera chithandizo kumatengera genotype lapansi. Lero tikudziwa mitundu 11 zomwe 6 Ambiri. Mu Russia, ambiri 1, 2 3 mtundu.

Zaka zingapo zapitazo chiwindi C anali mwa gulu la matenda osachiritsika. Therapy imachitika makamaka interferon, akanakhoza kwambiri kusintha wodwalayo, koma alephera kwathunthu.

Yojambula mankhwalawa matenda wakhala mankhwala "sofosbuvir," imene inatuluka mu pharmacies pa malonda osiyana dzina "Sovaldi". Pakali pano, pali njira zingapo bwino analogues:

• "Viropak";
• "Gratitsiano";
• "Geptsinat";
• "Gopetavir".

Nthawi zambiri bwino analekerera ndi odwala, koma nthawi zina anati:

• mutu;
• nseru;
• tulo;
• chilakolako imfa;
• kupweteka;
• migraine;
• maganizo;
• Ndikumva dryness mkamwa;
• ululu pachifuwa;
• tsitsi imfa.

The drawback yekha wa zimenezi - (. Avareji 10 000-12000 tsa pa paketi) a mtengo wapatali kwambiri, Amene, malingana medicament anasankha zingasiyane oposa kapena downwards.

reinvestigation

Pambuyo kuchipatalako wosatha ku masabata 12 mpaka 24, wodwalayo nkhani ya kusanthula mobwerezabwereza pamaso pa RNA tizilombo m'magazi.

Pankhaniyi, njira ndi pakhomo osachepera tilinazo ayenera kugwiritsidwa ntchito, popeza pambuyo kukhudzana ndi matendawa ndende mankhwala mwina n'zosatheka. Pankhaniyi chithandizo ayenera anapitiriza.

Chifukwa zoipa ndi kupanda chiwindi C HIV RNA pamene tizilomboto ali wapezeka. Phunziro angafunike nthawi yocheza zambiri (pa intervals lalifupi), kuonetsetsa kuti mankhwala wopambana.

kupewa

Aliyense amene wakhala nthawi yaitali ndi mankhwala okwera mtengo kwa chiwindi C, tiyenera kukumbukira kuti ndi thupi lake sangabereke chitetezo chokwanira, kotero reinfection n'zotheka.

Matendawa N'chapafupi kupewa kuposa kuchiza. Kwathunthu mungadzitetezere ku zoopsa sachiza, koma kuti osakhala ndi kufunsa izo zikutanthauza, "matendawa RNA wapezeka", njira zotsatirazi chiyenera kuchitika:

• sagwiritsa ntchito munthu ukhondo zinthu anthu ena (malezala, lumo, yarns mano);
• Pewani kugonana mosadziteteza;
• pitani pa mano, salons (kukongola, zizindikiro, etc ...) yekha ndi mbiri yabwino;
• kutseka onse kuwonongeka pulasitala kapena bandeji khungu;
• kutali zedi kuti musayandikire munthu amene akudwalayo.

kaonedwe

The kale matenda anali wapezeka, ndi aluso mankhwala adzakhala. Childs, pakalibe mkati limba chiwindi C akhoza atachiriratu ndipo popanda zotsatira.

Ngati sanalandire chithandizo chiwindi C, iye posapita nthawi kuyambitsa matenda enaake kapena khansa chiwindi. Izi zingachitike zaka ngakhale pambuyo 30-40 pambuyo asatenge kachilombo.

Matenda enaake, amene anaonekera mchikakamizo cha chiwindi C ndi aakulu osachiritsika matenda. Langoyamba n'zotheka m'mbuyo otaya mu nkhani ya kuthamanga yekha amene angapulumutse anthu chiwindi kupatsidwa zina.

Atamva zinthu zabwino kwa chiwindi C, musati yomweyo mantha. Choyamba, muyenera onani mkhalidwe wa chiwindi wanu ndi kuyamba kulimbana ndi matenda ndipo comorbidities. Mankhwalawa ndi yaitali ndi okwera mtengo koma amapereka mtima mwayi pa yaitali ndi moyo.