"Finoptinum": malangizo ntchito, zikuchokera, Akhristu enieni

Kuchokera mu mtima ndi matenda mtima zimakhudza anthu ambiri. Komanso, ndi zaka, chiopsezo limati ngati matenda ali kwambiri. Kuchepetsa chiopsezo njira aakulu mu thupi, madokotala kulengeza ntchito zipangizo zapadera. Pakati pawo makamaka wotchuka ndi kashiamu njira blockers. Iwo ndi gulu sakanikira mankhwala. limagwirira zochita amagwirizana ndi luso ziletsa malowedwe a ayoni kashiamu ku malo extracellular mu maselo ndi mitsempha ya mtima. Kuchepetsa ndende ya zinthu izi, medicament ochitachita vasodilating kanthu.

Mankhwala yabwino kwambiri ndi katundu amenewa ndi "finoptinum". Malangizo ntchito zikuchokera, analogs, zikuonetsa ntchito mankhwala ndipo zotsatira zake zam'mbali akufotokozedwa hereinafter.

Fomu, zikuchokera

Kodi mawonekedwe ndi khalidwe la mankhwala "finoptinum" chiyani? Malangizo pa ntchito akunena kuti zikhoza kugulidwa monga jakisoni ndi mankhwala.

Ngati zosakaniza yogwira wothandizila izi amachita verapamil hydrochloride. Komanso yokonza monga kugwirizana osiyanasiyana othandiza (malingana ndi mitundu kumasulidwa).

zotsatira pharmacological

Kodi chalakwika chibadidwe mankhwala "finoptinum"? Malangizo ntchito, ndemanga amati ndi kashiamu njira blocker (kusankha) kalasi yoyamba. Ndi ndilochokera difenilalkilamina ndipo akusonyeza antianginal, antihypertensive ndi kanthu antiarrhythmic.

zotsatira Antianginal za mankhwala ndi wachibale umatha bwanji myocardium ndi hemodynamics zotumphukira. M'mawu ena, mankhwala amachepetsa kamvekedwe ka mitsempha. Komanso kumachepetsa transformatsiiyu ATP mphamvu kuti uli mu ubale mkulu-mphamvu mu ntchito makina ndipo kumachepetsa m'mnyewa wamtima contractility.

Tiyenera kuona kuti ntchito mankhwala kwambiri kumachepetsa m'mnyewa wamtima O2 ndipo ali chronotropic zoipa, inotropic ndi zotsatira vasodilatory.

katundu wa mankhwala

Chifukwa kapangidwe kake, ndi medicament "finoptinum", analogues zimene zili m'munsimu, limaleka automaticity la nkusani mfundo kumachepetsa AV-conduction ndi kumawonjezera nthawi refractory.

Kuwonjezeka nthawi yosangalala diastolic ventricle (kumanzere), mankhwala amachepetsa tonus m'mnyewa wamtima khoma, i.e. ndi njira wothandiza zochepetsera obstructive hypertrophic cardiomyopathy.

Iwo ayenera kukumbukira kuti ankaona mankhwala chikusonyeza katundu odana arrhythmic ndi arrhythmias supraventricular.

The kinetics wa mankhwala

Kukonzekera "finoptinum" malangizo amene pansipa, imatsala pa kapepala m'mimba (pafupifupi 90% ya mlingo). kuyanjana ake ndi mapuloteni ndi 90%.

mankhwala ndi zimapukusidwa mu ndime (choyamba) kudzera chiwindi. Izi ndipamene otumphukira monga norverapamil kuti si hypotensive ntchito kuposa verapamil unmodified.

Hafu ya moyo nthawi ya mankhwala pa chiphaso cha mlingo umodzi ndi maola 3-8. Pa ntchito Mlingo mobwerezabwereza medicament, chithunzi ichi zimasiyanasiyana (maola 5-12).

Linachokera mankhwala kudzera matumbo ndi impso.

umboni

Nthawi zina, mankhwala "finoptinum"? Malangizo ntchito (mapiritsi ndi njira injectable chimodzimodzi modzionetsera) limanena kuti chida ichi chikhonza kwa supraventricular tachycardia (kuphatikizapo paroxysmal, syndrome Lown-Ganong-Levine ndi WPW-syndrome), kufa ziwalo (voteji, khola popanda vasoconstriction, khola vasospastic), nkusani tachycardia, matenda flutter, matenda tachyarrhythmia, matenda arrhythmia, hypertensive mavuto (kwa makonzedwe mtsempha), matenda oopsa, n'kofunika oopsa mu hvs ang'onoang'ono kupezeka, hypertrophic obstructive cardiomyopathy.

contraindications

Pamene kupereka "finoptinum"? Malangizo ntchito (jakisoni ndi miyala ndi contraindications yomweyo) akusonyeza kuti chida ichi ndikoletsedwa ntchito hypotension kwambiri, sinoatrial anazinga ndi odwala nkusani syndrome (kupatula odwala ndi pacemaker a), AV-anatseka misewu wachitatu ndi wachiwiri digiri syndrome Launa -Ganonga-Levin ndi WPW-syndrome osakaniza fibrillation matenda kapena matenda flutter (kupatula anthu odwala pacemaker a), mimba, hypersensitivity kuti verapamil, yoyamwitsa.

Mankhwala "finoptinum": malangizo ntchito

Mlingo wa mankhwala kuchita masamu dokotala payekha.

odwala wamkulu piritsi chikuyendetsedwera pakamwa pa mlingo koyamba kwa 40-80 mg wa katatu patsiku. Likamanena mlingo limodzi chosunga kumasulidwa mlingo ayenera chinawonjezeka ndi pafupipafupi makonzedwe - m'munsi.

Kids zaka 6-14, mankhwala tikulimbikitsidwa kuti atenge kuchuluka kwa 80-360 mg wa pa tsiku, ndi zaka 6 - pa mlingo wa 40-60 mg wa pa tsiku. Pafupipafupi ka mankhwala ndi kanayi pa tsiku.

Ngati ndi kotheka, mankhwala mu funso angathe kuperekedwa kudzera m'mitsempha (pang'onopang'ono). Choncho ndikofunikira kuyan'ana ECG, kuthamanga kwa magazi ndi kugunda kwa mtima wa wodwalayo.

Disposable njira mlingo anthu wamkulu ndi 5,10 mg. Ngati zotsatira achire palibe, mphindi ndiye pambuyo 20 kukonzekera akhonza analowa (pa mlingo yomweyo).

A umodzi mlingo injectable mawonekedwe a mankhwala ana zaka 6-14 wa zaka 2.5-3.5 mg pa ana a zaka 1-5 - 2-3 mg, ndi kwa mwana mpaka chaka chimodzi - 0.75-2 mg.

Odwala aakulu chiwindi tsiku mlingo sayenera upambana 120 mg.

Mlingo pazipita kukonzekera m'kamwa patsiku ndi 480 mg.

zotsatira zoyipazi

Kukonzekera "finoptinum" kungakhale zotsatirazi zochita mbali:

• kunenepa, bradycardia, agranulocytosis, kapena akuchuluka mtima kulephera, hyperprolactinemia, tachycardia, imfa chosakhalitsa cha masomphenya, edema zotumphukira;
• Amowabu kuchepetsa magazi, gynecomastia, galactorrhea, nyamakazi, angina, arrhythmia, edema m'mapapo mwanga, AV-chipika cha mlingo lachitatu, asystole, thrombocytopenia asymptomatic, kugwa;
• nseru, stiffness mu mikono kapena miyendo, gingival hyperplasia, kukomoka, kutopa, kuwonjezeka kudya, nkhawa, kuwonjezeka transaminases chiwindi;
• ziwengo, chizungulire, kudzimbidwa kapena m'mimba, mutu, maganizo, sedation, matenda extrapyramidal, kutopa, ankatenthetsa wa khungu, tulo, exudative erythema multiforme, pruritus.

Mwanjira mankhwala

Kodi n'zotheka kuphatikiza ndi mankhwala ena mankhwala "finoptinum"? Malangizo pa ntchito limanena kuti kuphatikiza kwa wothandizila awa ndi mankhwala antihypertensive matanthauzo kwalimbitsa mmene antihypertensive.

Ndi utsogoleli mtsempha wa verapamil anthu omwe inalandira mlingo wa beta-blockers, pali chiopsezo hypotension (wolumikizira) ndi asystole.

Pamene co-kutumikiridwa "finoptinum" mankhwala ndi beta-blockers, mankhwala inhalation mankhwala ochititsa ndi mankhwala antiarrhythmic kumaonjezera ngozi ya kudwala mtima kulephera, bradycardia, hypotension kwambiri ndi AV-anatseka misewu.

Pamodzi ndi chikuonetseratu "Amiodarone" nakweza bradycardia, zoipa inotropic tingati AV-chipika ndi conduction chisokonezo.

Chifukwa verapamil kumabwezera mmbuyo isozyme CYP3A4, nawo kagayidwe wa simvastatin, lovastatin ndi atorvastatin zina mawonetseredwe mogwirizana kuti chifukwa cha kuwonjezeka magawanidwe a statins m'magazi. milandu rhabdomyolysis ndi inunso.

katundu antianginal "finoptinum" nakweza pamene pamodzi ku feteleza.

Pamodzi ndi chikuonetseratu asidi acetylsalicylic ndi kuchuluka magazi nthawi chifukwa zowonjezera antiplatelet kanthu.

Kodi ndingachite "Dizopiramid" pamodzi ndi mankhwala "finoptinum"? Malangizo ntchito inanena kuti kuphatikiza kungayambitse hypotension kwambiri ndi kugwa, makamaka anthu ndi kulephera decompensated mtima kapena cardiomyopathy.

Pamene ntchito mapiritsi komanso njira kumawonjezera ndende zake magazi ndi "imipramine", umene chiopsezo kusintha osafunika pa ECG. Iwo ayenera kukumbukira kuti verapamil kumawonjezera bioavailability wa "Imipramine", kuchepetsa chilolezo chake.

Ndi osakaniza mankhwala ndi "carbamazepine" kanthu kumatheka mwa yamasika, komanso kumaonjezera ngozi ya mavuto kuchokera CNS.

Pa nthawi yomweyo kutenga mankhwala ndi "clonidine" pali milandu kulephera mtima anthu ndi matenda oopsa.

Pamene kaphatikizidwe wa medicament ndi mawonetseredwe lifiyamu carbonate wa ankachita mankhwala ndi osadalirika ndi kusakaniza. Pali milandu neurotoxicity, bradycardia kwambiri, kumapangitsanso zotsatira za lifiyamu ndi kuchepetsa ndende zake magazi.

Monga "Rifampicin" zochita pa mankhwala "finoptinum" chiyani? limati Manual kuti kuphatikiza induces chiwindi michere, kufulumiza kagayidwe wa verapamil. Izi mapeto kuchepetsa matenda efficacy wa mankhwala pansi kulingalira.

ayamikira yeniyeni

Zimene muyenera kudziwa musanagwiritse ntchito mankhwala "finoptinum" (40 mg)? Guide inanena kuti chida ichi ntchito mosamala pamene AV-anatseka misewu ya mlingo woyamba, aakulu kung'ambika stenosis, bradycardia, m'mnyewa wamtima infarction ndi pamaso pa kulephera kumanzere yamitsempha yamagazi, congestive mtima kulephera chikhalidwe aakulu, zolimbitsa kapena wofatsa hypotension, kwa chiwindi kapena insufficiency aimpso. Mosamalitsa mankhwala tikulimbikitsidwa okalamba ndi ana.

Mu pachimake akufunika kuchitidwa ndi osakaniza mankhwala a matenda oopsa ndipo angina ndi verapamil ndi beta-blockers. Koma m'pofunika kupewa utsogoleli mtsempha wa masika.

Pa phwando izi zikutanthauza wodwala angathe maganizo payekha monga kugona kapena chizungulire, zomwe zingakhudze luso munthu agwire ntchito woopsawo.

Mimba ndi mkaka wa m'mawere

Kaya m'tsogolo abereka chinafotokoza mankhwala "finoptinum"? Malangizo ntchito pa mimba ali kuti zimenezi zikutanthauza zimakhudzanso chowawa pa chitukuko yoopsa. Komanso akudutsa mu mkaka wa m'mawere. Choncho, pansi pa zikhalidwe izi mankhwala ali mosamalitsa contraindicated.

Medicament "finoptinum": Anzawo ndi mtengo

Mtengo wa chida ichi angakhale osiyana. Monga ulamuliro, izo zimatengera mtundu wa amasulidwe mankhwala, kuchuluka kwake anamvetsa. Wapakati mtengo "finoptinum" ndi 100-170 rubles.

Ngati ankaona mankhwala muli contraindicated, tingathe m'malo ndi imodzi mwa njira zotsatirazi: "Verapamil", "Verogalid" "Verapamil-OBL", "Kaveri", "Verapamil Sopharma", "Verapamil-Lect," "Verapamil-Verein" "verapamil-ratiopharm" "Isoptin", "verapamil-Escom," "Vero verapamil," "verapamil hydrochloride" "Lekoptin".

Reviews madokotala ndi ogula

Akatswiri amanena kuti miyala ndi njira "finoptinum" ndi ogwira ndi yotchipa njira, amene cholinga kubwezeretsa magazi, ndi bwino bwino kukhala matenda ena a zotengera mtima ndi magazi.

Koma odwala, ambiri a iwo okhutira ndi zotsatira za mankhwala ndi wothandizila izi. Mapiritsi kapena mtsempha kulowetsedwa njira facilitates Kupha mofulumira zizindikiro za matenda oopsa ndi zizindikiro zina matenda a dongosolo mtima.

Tiyenera kuona kuti za mankhwala napeza zoipa. Iwo amalankhula za ambiri zochita mbali zimene zimachitika nthawi yomweyo pambuyo ntchito mankhwala. Komanso, owerenga ambiri akudandaula za contraindications ambiri.