Dubin-Johnson syndrome: kufotokoza, matenda, zizindikiro ndi mankhwala

Ngakhale kuti mankhwala amakono apita patsogolo kwambiri ndi matenda ambiri salinso chiweruzo kwa odwala, ena mwa matenda amenewa si bwino. Mmodzi wa iwo ndi matenda Dubin-Johnson. Chipatala, matenda ndi mankhwala a matenda zikhoza kuti akatswiri thanzi la anthu ena chidwi. Taganizirani funso ili mwatsatanetsatane.

Ozungulira syndrome ndi matenda Dubin-Johnson - ochepa chabe cholowa matenda chiwindi Similar inakula matenda a chikasu ndiyo.

zimayambitsa

Dubin-Johnson syndrome alinso dzina lina: enzimopaticheskaya matenda a chikasu ndiyo chiwindi. Vutolo limachitika mwa kuphwanya yoperekera mu ya ndulu ku maselo chiwindi a bilirubin.

Zinthu zimenezi zikuoneka mu thupi kuchotsa therefrom erythrocytes kuonongeka kapena inawonongedwa. Kutsiliza bilirubin kumachitika m'njira ziwiri:

• kuwonjezera kuchuluka kwa mankhwala akutuluka kudzera ya ndulu ya;
• wochepa mkodzo kupita.

Dubin-Johnson syndrome kumachitika pamene akusokoneza mayendedwe a bilirubin kudzera ya ndulu ya. Ichi ndi matenda osowa kwambiri atengeke anyamata ambiri (pafupifupi 20-30 zaka). milandu matenda kuyambira kubadwa nthawi zina zimachitika. Kusatetezeka utatha m'badwo wa munthu zaka 50 kapena kuposerapo ndi kochepa.

Chifukwa cha majini a matendawa, Dubin-Johnson chifukwa kusintha losokonekera, kuchita nawo katundu wa bilirubin mu chiwindi ndi kabisidwe mapuloteni.

zizindikiro

Dubin-Johnson syndrome, zizindikiro zimene ziri khalidwe la matenda ena monga Mwachitsanzo, kutopa, ndi amakhazikitsa mbali mwini zimasiyanitsa:

• ululu mu nthiti kumanja;
• ngakhale pang'ono kudya;
• pangakhale pang'ono kuyabwa khungu;
• yatupa chiwindi;
• colic, nthawi zina kumawonjezera;
• kusanza;
• kutentha kuwonjezeka.

Mawonetseredwe ali nakweza chifukwa cha matenda opatsirana, kwadzaoneni m'thupi ndi m'maganizo zimamuchulukira. Kwa amayi, nkotheka aggravation pambuyo madyedwe a kulera.

gulu chiopsezo

Zomwe gulu la anthu ayenera kukhala osamala za matendawa?

matenda ndi cholowa. Ngati banja anali ana ndi matenda, awiri pa siteji ya mapulani a mimba m'pofunika mayeso onse, mayesero zofunika ndi kukaonana ndi katswiri. ayamikira anthu ndi zogwirizana ndi mabanja amenewa, kuphatikizapo mmodzi wa akazi kapena awo achibale zowawa syndrome Dubin-Johnson.

The ndondomeko matenda

Mwachirengedwe, matenda ndi ambiri mwa Ayuda aku Iran. chiwerengero chawo chimakwera kufika pa 70% ya kulemera okwana odwala matenda.

Nkofunika kuti pafupifupi munthu moyo pachiswe Dubin-Johnson syndrome. CHITSANZO odwala akutitsimikizira nkhani imeneyi. Madokotala anafufuza moyo amayembekezeka odwala matenda ndipo anaona kuti sichichititsa imfa.

Pafupifupi 25% ya odwala kubva mu hypochondrium bwino. Kapangidwe ka chiwindi si bwanji, palibe mapindikidwe mu matendawa. Koma pa nthawi yomweyo mu minofu yake kuoneka mawanga akuda, chifukwa mu thupi amasintha mtundu wake kuti zobiriwira kapena woderapo. Mbali imeneyi ya syndrome imatchedwa makeke chokoleti Chip. Amenewa zimatheka ndi katulutsidwe wakuswa metabolites.

Matendawa ali ndi madokotala ananena zawo zabwino, ngakhale kuti akhoza kupitiriza mu moyo wa wodwalayo.

Gome m'munsimu amasonyeza deta pa udindo wa ziwalo za odwala.

diagnostics

Dubin-Johnson matenda, matenda amene chikuchitika mu magawo angapo, anatsimikiza mtima kufufuza.

• Ndi kuvomerezedwa kuti ultrasound wa pamimba.
• General magazi ndi mkodzo mayesero.
• Analysis magazi ndi mkodzo kuti bilirubin. Monga ulamuliro, iwo abwino kwambiri.
• Zitsanzo fenobarbetalom.
• Zolembera za matenda.
• Zitsanzo bromsulfaleinova.
• Coproporphyrin mtengo zizindikiro mu mkodzo patsiku.
• The zili ndi michere mu magazi.

Ikani ena njira zina matenda.

Pamaso pa Dubin-Johnson odwala matenda kukaonana ndi dokotala.

Kuchiza ndi kupewa

Dubin-Johnson matenda, zomwe chithandizo chimenechi salolera kulandira kukonzekera mwapadera olamulidwa ndi zodzitetezera:

• kutsatira zakudya ovuta ntchito mavitamini B, si mchere; kutetezera;
• kuchepetsa zinthu nkhawa;
• kuchepetsa zinthu zolimbitsa thupi;
• chokana mowa;
• Zonse kuwunika milingo bilirubin pa moyo wa moyo wodwalayo.

M'pofunikanso kukumbukira kuti mimba mwina vutoli matenda. Mankhwala kuthandiza kuchiza matenda Dubin-Johnson, panopa sunayambe.

Mofananamo, chikhalidwe cha matenda ndi ozungulira syndrome.

Kufotokoza mwa chidule za

Ozungulira syndrome komanso ndi matenda otengera zokhudza chiwindi. kusintha amaloŵamo mu yobereka bilirubin, ntchito enzyme kukhala zachibadwa. Tikhoza kunena kuti matenda ndi opepuka mtundu wa matenda Dubin-Johnson tafotokozazi. Zizindikiro anasonyezanso pang'ono lililonse limatisokoneza.

Matendawa angasonyeze ngati chibadwire ana. Bilirubin mu magazi a wodwalayo Mukhoza kumasuka ndi kuchuluka. Panali kusiyana kwa ndulu ya.

syndrome ozungulira amakhala ndi chakuti mu hepatocytes palibe zili inki bulauni. Osati pali zotsatira, amene amadziwika ngati makeke chokoleti Chip. Chifukwa cha matenda ndi wosiyana pang'ono kwa syndrome Dubin-Johnson. Pankhaniyi, chiwindi sangathe kulimbana ndi mayamwidwe bilirubin. Chifukwa, kulephera undigested mankhwala kumbuyo mu magazi. Pa mfundo imeneyi, mu mtima akufotokozera giperbulemiya. Yabwino madokotala ananena zawo za matendawa.

Pa nthawi ya matenda lidofreninom chiwindi, ndulu ndi ducts akalipo.

zizindikiro syndrome

Zizindikiro ozungulira syndrome ndi ofanana kwambiri ndi zizindikiro za matenda Dubin-Johnson:

• Wonse anasonyeza matenda a chikasu ndiyo.
• Maganizo kuwawa pakamwa.
• Kupweteka kwa hypochondrium bwino.
• Pamene Dubin-Johnson matenda, chiwindi odwala kuchuluka kukula. Pankhani ya matenda ozungulira ndi kuchuluka yekha zina.
• misinkhu apamwamba bilirubin m'magazi.
• chiwindi mayesero ntchito n'zabwinobwino.
• MAGAZI popanda kusintha.
• The bioptome chiwindi palibe kudzikundikira inki.

Kulosera tsogolo la matenda ambiri yabwino, matendawa amapezeka pa zaka zambiri, nayenso si kunyengerera anthu thanzi.

matenda a matendawa

Matendawa akhoza kuyika pa matenda mwatsatanetsatane za chamoyo.

Maphunziro imachitika kwa zasayansi kuthandiza anathandiza zili bwino bilirubin m'magazi. Pakuti matenda ndikofunika kudziwa chiwerengero cha coproporphyrin zili mu mkodzo.

Odwala kwambiri, nthenda ili m'kati popanda zizindikiro zilizonse.

Pankhani ya matenda a syndrome ozungulira amathera Kupenda chiwindi: lake X-ray ndi ultrasound. Pomaliza chomwecho kukumana ndulu ndi ducts.

kupewa matenda

General zodzitetezera ali motere:

• kuchepetsa zinthu zolimbitsa thupi;
• zochizira matenda kugwirizana ozungulira syndrome;
• Pewani nkhawa ndiponso maganizo.

Zinthu za kuwonjezeka kwa bilirubin m'magazi

ukuwonjezeka Bilirubin pa zifukwa zotsatirazi:

• nkhawa chaukali;
• salimbikitsa zakudya, zakudya kuphwanya;
• ntchito mankhwala;
• ntchito kwambiri mowa.

mankhwala a matenda

njira Common kuthetsa matenda kumeneko. Komabe, ayenera kutsatira njira zodzitetezera. Monga mankhwala muyenera zikutanthauza kuti bilirubin linanena bungwe thupi. Ya ndulu zambiri mankhwala ntchito.

Sankhani chithandizo choyenera kuthandiza dokotala.