Chotupa chikhomo HE4: decoding ndi mlingo chizindikiro

Oncology - vuto loopsa. Chaka chilichonse chifukwa cha matenda imapha anthu ambiri. Chachinayi odziwika chifukwa cha khansa ya mazira a. Komanso, amafa ndi yayikulu kwambiri m'madera otukuka. Cancer angathe kuchiritsidwa ngati kuzindikiridwa pa siteji oyambirira a chitukuko. Izi zingathandize zaminyewa chotupa chikhomo HE4 khansa yamchiberekero. Kodi mtengo wa index uyu adzakhala pansipa.

Pa fomu iyi khansa

Zizindikiro zambiri kuzindikira ndi zovuta, popeza kuti n'zogwirizana ndi mapangidwe chotupa mu zokhudzana ndi Choncho bwinobwino. Malinga ndi mfundo operekedwa ndi Agency Mayiko kafukufuku pa Cancer, ndi zaka zisanu kupulumuka mlingo wa odwala yamchiberekero khansa mu magawo otsiriza pafupifupi 46%. Koma ngati muli ndi kamtima matenda mu magawo oyambirira, mlingo kupulumuka ziwonjezeke kwa 94%. Akatswiri ofufuza wapatsa anthu mwayi kulimbana matenda. Kudziwa isanayambike chotupa chija mu magawo oyambirira a zolembera chotupa mu phunziroli. Ndi kuwonjezeka mu msinkhu wawo madokotala akuchenjeza. M'nkhani ino tikambirana chotupa chikhomo HE4.

Khama la chotupa chikhomo

Mu thupi la munthu pali zinthu mu buku laling'ono, limene amatchedwa zolembera chotupa. Iwo nawo mabungwe osiyanasiyana thupi ndi amuzolengedwa ndipo si owopsa kuchuluka yachibadwa. Zonse zikhala osiyana, ngati voliyumu awo amayamba kuonjezera. Izi zikusonyeza Mwina chotupa chija. Mwachitsanzo, kudziwa khansa yamchiberekero, ambiri amangoti ntchito CA 125 chotupa pentopeni. Koma patapita chotupa chikhomo HE4 molondola kwambiri imalongosola Oncology.

Izi mapuloteni serous kuti midadada enzyme protease, njira anawamasulira kuti "munthu mapuloteni -. Anayi mafuta" Chofunika ping'ono ndi mu testis ndi umuna ntchito mu chiphunzitso cha. Komanso ndi dongosolo la kupuma, mazira chubu, ndipo zimagwira ntchito zosiyanasiyana mucous. Koma mmene umagwira ntchito ndi mmene zimakhudza pepsin payekha, komabe si bwino.

Zikuonetsa kuti cholinga kusanthula

A pang'ono chotupa chikhomo HE4 akhoza kukhala mkazi aliyense. voliyumu yake ukuwonjezeka matenda monga:

- yamchiberekero khansa.

- Oncology endometrium.

- khansa.

- M'mapapo khansa.

Benefits HE4

Choncho oncomarker HE4 zikutanthauza ndondomeko kale zilonda. Iwo sangakhoze kukhala otsimikiza ndi mtima wabwino ndondomeko, kapena kutupa thumba losunga mazira ndi. Izi anasonyeza mmene HE4.

kuloŵedwa m'malo, chotupacho chikhomo CA 125 amenenso umalimbana kuzindikira khansa, koma yaing'ono molondola udindo. Kuti ndi kuchuluka kwa CA 125 n'chachikulu mbali yotsirizira pa matenda zolondola. A buku HE4 ukuwonjezeka ndi zaka zitatu pamaso pa tanthauzo lenileni la matenda.

Choncho, pofufuza khansa akhoza wapezeka pa siteji oyambirira, silinafike anayamba zizindikiro. Ngakhale zili chomwechi, mawu olembedwa a chotupa chikhomo HE4 si ntchito mabungwe kafukufuku m'dera la thumba losunga mazira ndi. Iye sangakhoze kuzindikira nyongolosi ndi mitundu mucoid khansa.

HE4 ntchito kuwunika mankhwala a akazi kale. Choncho, ngati kusanthula chithandizo silidzandionanso, ndiye ntchito mankhwala akudutsa.

Malinga ndi chiwerengero cha chikhomo chotupa tingadziwire mapangidwe foci yachiwiri ya maselo chotupa chifukwa cha kusiyana inayamba choyambirira zimakhala moyandikana kapena watsopano.

Kulola kafukufuku HE4

Kuchititsa imfa kwambiri chifukwa khansara ndi kuzindikira matenda mu magawo lotsiriza la chitukuko. Mothandizidwa ndi HE4 pomaliza akhoza kudziwa pa siteji oyambirira a khansa, potero kuchepetsa mosavuta imfa. zolembera chotupa angathe kuonedwa mu magazi otengedwa mtsempha wa. Yobereka moyenera kuwunika ayenera:

• Ndalama magazi ndi mosamalitsa pa chopanda kanthu m'mimba kapena pambuyo maola anayi kapena asanu pambuyo chakudya. Mukhoza kumwa madzi, koma osavomerezeka chifukwa khofi kapena madzi.
• Ngati nkotheka, masiku angapo (masiku 3-4) pamaso yobereka kuwunika sanatenge mankhwala aliwonse.
• Pamaso kusanthula aliyense alibe kumwa kapena kusuta.
• Chiyambi cha mankhwala mkazi dzanja pa kusanthula kamodzi miyezi itatu iliyonse. M'tsogolo, chokwanira cha munthu - kawiri pa yachinsinsi.

Nthawi zina, kafukufuku kutumikiridwa kwa ana. Iwo ayenera kumwa madzi owiritsa kwa theka la ola pamaso yobereka a kuwunika. Voliyumu pafupifupi ya kumwa madzi ayenera kukhala 150-200 ml.

Akazi ayenera kuyesedwa ngati panali zowawa m'dera m'chiuno, akusokoneza msambo, yafupika kudya.

Mu phunziro ndikofunika kuzindikira mkulu mlingo wa chotupa pentopeni.

Chotupa chikhomo HE4: mawu olembedwa

Wakudziko zimadalira kugonana, m'badwo wa wodwalayo. Pambuyo atayezetsa anamuyika, muyenera kudikira. Zotsatira zake zidzakhala okonzeka mu masiku angapo.

Volume HE4 kuzindikira ndi kuphunzira mwapadera chemiluminescent.

Mfundo yofunika ndi izi: pali mankhwala anachita zaikidwa ndi kufunika 4-TH mapuloteni. Ndiye pali kusintha katundu wawo mwachibadwa. The chothandizira akapsa ndi luminescence anachita. Tsopano mothandizidwa ndi njira malangizo kudziwa ndi kuwerengera mlingo wa chotupa pentopeni.

Malamulo a amuna ndi akazi

A chokwanira cha mapuloteni-4 akazi pa chisanadze kusintha sali wamkulu kuposa 70 pmol / l, ndipo pambuyo kusintha - zosakwana kapena wolingana 140 pmol / L. The zambiri zizindikiro izi, wamkulu mosavuta matenda a khansa yamchiberekero.

Koma muyenera ndithudi ndikudziwa kuti pali zaka malamulo, ndiye deta lisinthike malingana m'badwo. Choncho ndi bwino kupeza mfundo zonse kuchokera dokotala. Ichi ndi chimene chimasonyeza chotupa chikhomo HE4.

Tili zotsatirazi chidwi Ndipotu. Pamene anagwira HE4 mawu olembedwa, iwe deta zotsatirazi: theka la theka wamkazi wa anthu chawonjezeka chiwerengero cha chotupa chikhomo, koma CA 125 zambiri amakhalabe ponseponse chovomerezeka.

mlingo wa wa amuna ndi chiyani? Ndi pa mlingo wa 4 ng / ml ya ndipo pansipa. Kodi kukhala osamala ngati akapeza ntchito mwamphamvu kwambiri. Iwo akhoza kulankhula za chitukuko cha khansa mu thupi la matenda oopsa.

Pali kusintha ndi malamulo zaka. Patatha zaka makumi anai amuna mlingo wa 2-2.5 ng / mL, patatha zaka makumi asanu - 4.5-6.5 ng / mL.

Kafukufuku amasonyeza kuti anthu ambiri a mibadwo yonse kupita kuchipatala. Iwo anakweza zolembera chotupa mu magazi ndipo ali ndi kudwala ku prostate.

kusanthula zolakwa

Ziyenera adzanyamula kukumbukira kuti kusanthula makhalidwe kwa zolembera chotupa si chifukwa kutsimikiza kapena kutsutsa Oncology. Molondola koma ntchito HE4 ndi nkhani zina. Ndi bwino kufufuza izo pamodzi ndi CA 125. Ndi kuchita mitundu yosiyanasiyana ya diagnostics, monga zasayansi zoimbidwa.

Nthawi zina mtengo wapatali wa chotupa zolembera HE4 si chifukwa chotupa chija. Tidzaona bwinobwino wabodza zabwino kwa:

• pamaso pa zokhudza zonse cholowa matenda, limafotokoza zimene kusintha transmembrane yang'anira jini;
• kukhalapo kwa ena urogenital inflammations dongosolo;
• aakulu aimpso kulephera;
• yamchiberekero chotupa;
• myoma.

Kodi kuzindikira zizindikiro za khansa?

Pa zipolowe pang'ono m'thupi m'pofunika dokotala. Adzamuika kusanthula pa zaminyewa chotupa chikhomo HE4 khansa yamchiberekero. Lamulo kapena zopatuka tidzamvetsetsa msanga. Poyamba zizindikiro mwina sinkapezeka. Koma Mulimonsemo, kukumbukira ayenera kukhala pa:

• kuyan'anila mu thumba losunga mazira ndi mavuto ndi kusamba mu akazi;
• pachimake ululu m'dera m'chiuno;
• kuwonongeka mu umoyo ndi chilakolako yafupika;
• nkhanza ndi wodzikweza kuwonda;
• mphwayi.

Pa chitsimikiziro cha matenda safunikira mantha, chifukwa khansara ali bwinobwino ankachitira lero. Ndithudi, izi ndi mayeso, koma tingagonjetse ndipo tuluka mwa nkhondo wopambana.

Self-mankhwala ndi zosavomerezeka kudalira akuima yekha pa malangizo a akatswiri.

Kudzatenga chipiriro ndi mphamvu, chifukwa mankhwala - ndi khama, lomwe lili ndi khalidwe yaitali ndi zosasangalatsa.

Pomaliza

The chifukwa olakwika mwina, ngati chotupa si kupanga HE4 kapena lilipo zedi osakwanira kudziwa.

Ngakhale kuti kuwunika adzakusonyezani, si koyenera kukhala wokwiya pasadakhale ndipo anapereka nokha kwa matenda. madokotala akhoza kudziwa matenda ndi mankhwala mankhwala, koma ndikatha kumfunsafunsa zonse.