Buserelin zofikira - kufotokoza ndi ntchito mbali

Kusankha mankhwala m'thupi zikhazikitsidwe mosamala kwambiri zizindikiro ndi chizindikiritso mosamala chiopsezo mavuto.

Kukonzekera "Buserelin Depot" akuyerekeza akutsutsana ndi zina Mwachangu ake okwezeka ndi otsika Mwina zizindikiro chowawa. Iye ndi membala wa wothandizila m'thupi anticancer.

The kanthu pharmacological mankhwala

kanthu ndizo buserelin antigonadotropnym, odana ndi androgenic, odana ndi esitirojeni, zotsatira odana ndi chotupa. mankhwala mankhwala "Buserelin Depot" ndi mpikisano anamanga kwa maselo maselo secreting gonadotropin-kumasuka Chinthu (ali mu dongosolo la Lobe zapambuyo wa pituitary England).

Mu gawo loyamba athandizira mankhwala zimawonedwa kuwonjezeka chosakhalitsa mu ndende ya LH ndi FSH (gonadotropic timadzi), allocated ndi pituitary, amene amatsogolera chinawonjezeka maliseche Gomonov okhutira. Pambuyo 14 - 21 masiku Letsani zikutanthauza gonadotropic ntchito ndi feedbacks zoipa, imbaenda kuchepetsa kwambiri a LH ndi FSH, ndipo chotsatira, ndipo kuchepa ulimi wa mahomoni kugonana. Choncho, mwamuna testosterone ndende amachepetsa, akafika mlingo umene unakhazikitsidwa pambuyo orchiectomy (zachipatala castration). Akazi mankhwala zotsatira "Buserelin Depot" ndi adatchithisira kuti mlingo wa estradioda kupanga alipo mu nthawi posklimaktericheskom.

Ntchito mankhwala "Buserelin Depot"

Ndi ntchito mankhwala a khansa prostate, zina, ntchito kuletsa kupanga testosterone mu testes lapansi. Ntchito mankhwala a khansa ya m'mawere (matenda timadzi amadalira, zomwe amakhala ndi kupanga mkulu wa estrogens kapena limapezeka endometriosis). matenda ena, kuchitira "buserelina Depot": fibroids uterine, endometrial hyperplasia, kuchititsa pologalamu lidzawagwiritsenso pochiza osabereka.

Contraindications ndi malangizo apadera

Hypersensitivity, orchiectomy, mimba, mkaka wa m'mawere. CHENJEZO kutenga mankhwala mu kudwala pa mundawo mkodzo pa mlingo wa metastasis vertebral, matenda oopsa, shuga, ndiponso maganizo. Buserelin kudzilimbitsa ndi mimba - mfundo atakwatirana.

zotsatira zoyipazi

Wodwala angadandaule za malaise pa mbali ya dongosolo chapakati mantha mu mawonekedwe a mutu, mantha, kusowa tulo, amnesia, utachepa ndende, chizungulire, kusakhazikika maganizo, ndipo nthawi zina maganizo. Iwo akhoza anamva tinnitus kapena chipsyinjo pa diso, amaona masomphenya kapena kumva. Nthawi zambiri mukhoza kukhala "otentha kwakekwake." Mlungu woyamba wa chithandizo akazi anati psevdomenstruatsiya, ndiye anapereka dryness ukazi, nkotheka fupa demineralization, utachepa libido. Anthu, matenda akhoza kulimbikitsa choyamba 2 - masabata 3, kapena kuoneka gynecomastia, yafupika potency. Chimodzimodzi kumachitika: anorexia, matenda dyspeptic. Buserelin kudzilimbitsa ndi mowa atakwatirana. Mu odwala matenda oopsa achuluke kuthamanga, kugunda kwa mtima. Ku thupi lawo siligwirizana zimachitika: kuyabwa zidzolo, bronchospasm, anaphylactic mantha. Kusintha zasayansi zizindikiro: dyslipidemia, hyperglycemia, kuwonjezeka transaminases ndi bilirubin, thrombocytopenia ndi leukopenia.

Mfundo za mankhwala

Dongosolo mu mnofu: kutumikiridwa yomweyo pambuyo yokonza kuyimitsidwa.

- pamene Prostate chotupa pa masabata 4 pa 4.2 mg.

- Endometriosis - umayamba mkati miyezi 4.

- ndi uterine myoma -3 miyezi.

- osabereka - 4.2 mg.

Dongosolo Intranasal:

- zochizira matenda wamkazi tafotokozazi - kutumikiridwa kwa m'mphuno 900 mg / tsiku (mlingo umodzi, 3 pa tsiku), 1 - 2 masiku a kuzungulira kusamba.

- osabereka 600 mg / tsiku, 1 mlingo wa m'mphuno kanayi pa tsiku. Ngati mwamphamvu anasonyeza anatseka misewu cha ziwalo zoberekera, mlingo yafupika nthawi 2.

Ena anati:

- Chithandizo ndi kansa ya prostate ikuchitika moyo;

- mankhwala odana androgen kutumikiridwa kwa masabata 2. ndipo kwa masabata 2. chithandizo ndi buserelin, kumathandiza mavuto omwe angagwe pa milungu yoyambirira chithandizo;

- mu nthawi yoyamba ya mankhwala mu akazi angaoneke yamchiberekero chotupa;

- ayenera kupewa mimba ndi kulera zosiyanasiyanazi kulandira mankhwala kuchitira buserelin, koma miyezi 2 m'pofunika kugwiritsa ntchito njira sanali m'thupi la kapewedwe;

- zotsatira zabwino pa mankhwala a endometriosis opaleshoni ndi kuchepetsa pafupipafupi musabise.

Mogwirizana ndi mankhwala ena

Buserelin amachepetsa zotsatira za mankhwala hypoglycemic. Chifukwa angayambitse yamchiberekero hyperstimulation, ngati ntchito limodzi ndi mankhwala kupanga kugonana mahomoni.