Analogue "ndi chloramphenicol" kutsekula m'mimba (mapiritsi). "Chloramphenicol" (madontho diso) analogs

Ambiri a ife bwino katundu wa mankhwala "Chloramphenicol", mungathe kupirira matenda osiyanasiyana. Ndi zothandiza matenda m'mimba matenda, kuphatikizapo amene ali limodzi ndi kutsekula m'mimba, ankagwiritsa ntchito mchitidwe ophthalmic mu etiology toyambitsa matendawa. Komabe, si nthawi zonse wolungama ndi ntchito za mankhwala, kotero dokotala mankhwala analogue a "ndi chloramphenicol". Nanga zipangizo akhoza wodwala, kutchereza.

Pharmacological katundu wa mankhwala "Chloramphenicol"

antibayotiki kukhala sipekitiramu yotakata kanthu, chifukwa katundu mafuta-sungunuka, mosavuta likulowerera maselo a tizilombo toyambitsa matenda ndi amachitira ndi thunthu la ribosomes bakiteriya. The chifukwa cha zotsatira amenewa ndi chisokonezo pepdidnyh kupanga kumangidwa ndi kaphatikizidwe mapuloteni. Choncho zikuoneka kuti yogwira mankhwala mankhwala ali bactericidal ndi kanthu bacteriostatic.

"Chloramphenicol" akugwira ntchito ndi tizilombo ta ambiri tizilombo amene ali kugonjetsedwa tetracyclines, sulfonamides ndi penicillin. Koma tizilombo mogwirizana - Mycobacterium TB ndi bowa - mankhwala, mwatsoka, alibe chochita.

Kukana kuti izi zikutanthauza tizilombo akufotokozera pang'onopang'ono. Chifukwa ziwalo komanso mkulu kawopsedwe wa mankhwala amagwiritsidwa ntchito pofuna kuchiza matenda aakulu opatsirana kwa amene zochepa kawopsedwe mankhwala antibacterial operewera.

Zikuonetsa ntchito ndi mawonekedwe kumasulidwa

Popeza chida ntchito m'madera angapo mankhwala, mankhwala atenga chisamaliro cha mayiko ntchito ndipo anayamba njira zitatu mankhwala. Choyamba - mowa njira, limene lakonzedwa ntchito panja. Iwo Kwalamulidwa kwa zilonda zam'mimba venous kuti sindimachiritsa kwa nthawi yaitali, komanso amayaka II ndi mlingo III. Kaŵirikaŵiri analimbikitsa yothetsera zotupa purulent, zithupsa ndi losweka nsonga zamabele amayi unamwino.

Bongo mawonekedwe piritsi akulangizidwa kutenga odwala matenda matenda monga kamwazi, paratyphoid, tayifodi, brucellosis, salmonellosis, tularemia, ubongo abscess, chibayo. Mofanana ogwira mankhwala kwa zosiyanasiyana Q malungo, inguinal limfagranuleme, yersiniosis, psittacosis, matenda thirakiti biliary, purulent peritonitis, chlamydia, matenda septic bala, ehrlichiosis, purulent otitis ndi mkodzo thirakiti matenda chiyambi bakiteriya.

Mawonekedwe lachitatu la wothandizira wa - eyedrops. Iwo ntchito ophthalmic kumapeto kwa mankhwala ndi kupewa matenda monga keratitis, conjunctivitis, blepharitis.

Zotsatira zoyipa za zipangizo

Izi wothandizila pharmacological, komanso mankhwala ena, koma zabwino katundu pharmacological angapo mavuto omwe angagwe pa mankhwala.

Ntchito ya mankhwala mu mawonekedwe piritsi zikhoza kubweretsa dysbacteriosis, dyspepsia, kusanza, kutsekula m'mimba ndi kuyabwa wa pharynx ndi M'mimbamo m'kamwa. Yankhani ku phwando zikutanthauza zavuta dongosolo hematopoietic, amene kumaonekera mwa mawonekedwe a thrombocytopenia, granulocytopenia, erythropenia, reticulocytopenia ndi leukopenia. Pasanathe ambiri, wodwala angathe aplastic magazi m'thupi kapena granulocytopenia. Kuchokera mantha dongosolo anachita "Chloramphenicol" Mapale kungakhale neuritis zotumphukira, chisokonezo, kuyerekezera zinthu m'maganizo zithunzi ndi Makutu, ndi psychomotor chisokonezo Al.

zosiyanasiyana chokhwima kugwiritsa ntchito mankhwala mu mawonekedwe njira kungakhale ziwengo, chidawoneka zotupa pa khungu kapena angioedema.

njira kandalama analogue

Waukulu yogwira zikuluzikulu za mankhwala ndi chloramphenicol. Choncho waukulu structural analogue "ndi chloramphenicol" - mankhwala ndi dzina lomweli "Chloramphenicol". Zikuonetsa ntchito zake zofanana kwa anthu amene anafotokozedwa malangizo ntchito "ndi chloramphenicol" malangizo.

Chida amapangidwa m'njira zitatu. Choyamba - mapiritsi ndi makapisozi munali 0,25 ndi 0,5 ga mfundo yogwira. Mawonekedwe chachiwiri ndi 25% ya madontho diso, lachitatu - ufa anafuna njira jekeseni.

Dziwani kuti, monga njira "Chloramphenicol" analogs munali chloramphenicol, ndi yotakata-sipekitiramu mankhwala ayenera kupatsidwa mwachindunji kwa dokotala. Nthawi wodzilamulira makonzedwe a gulu la mankhwala kumaonjezera ngozi ya mavuto.

Mankhwala "Levovinizol"

Wina structural analogue "ndi chloramphenicol," chomwe tsopano lingathe kukopedwa pa mankhwala a, amadziwika pansi pa malonda dzina "Levovinizol". Chifukwa cha nambala chida ntchito ndi chloramphenicol ndipo excipients. Mukhozanso mankhwala mu mawonekedwe a aerosol ndi, liniment, ufa lokonzekera yomalizidwa njira ndi mowa njira.

Perekani yogwira mankhwala matenda osiyanasiyana bakiteriya khungu chifukwa cha tizilombo atengeke. Komanso, madokotala nthawi zambiri ntchito mankhwala kuchiza odwala matenda ndi amayaka kwambiri ndi chabe, zilonda kuthamanga, zilonda trophic, kuchiritsa mabala, zilonda, mankhwala medicament akazi lactating ndi nsonga zamabele losweka.

Mosiyana ndi mankhwala "Chloramphenicol" analogues ano chifukwa ntchito apakhungu, makamaka mankhwala "Levovinizol" ndi yochepa mndandanda wa zotsatira zoyipazi, kotero iwo akhoza ntchito pofuna kuchiza ana chibadwire.

Pankhani contraindications, ndiye nawonso, osati kwambiri. Njira kuteteza anthu ndi hypersensitivity kwa zigawo zikuluzikulu, chopinga wa mafupa hematopoiesis, komanso anthu amene amadwala pachimake likukulira porphyria, akusowa shuga-6-mankwala dehydrogenase, aimpso kapena kwa chiwindi insufficiency, psoriasis, matenda a mafangasi a khungu, chikanga.

Amatanthauza "sintomitsina"

Akuyesera kuthetsa funso la chimene chiri mankhwala "Chloramphenicol" ofanana ndi analogues, onetsetsani kuti kutchula medicament "sintomitsina". mankhwala Izi kawirikawiri Kwalamulidwa kwa odwala ndi amayaka kachilombo 2-3rd mwamphamvu, sanali kuchiritsa zilonda trophic ndi matenda osiyanasiyana bala.

Pa mtima wa mankhwala amatanthauza chloramphenicol. Monga zigawo wothandiza kulenga mlingo umodzi mawonekedwe mankhwala ntchito wamba Kasitolo mbewu mafuta, asidi sorbic, madzi mwayeretsa, emulsifier № 1 ndi carmellose ndi sodium 70/450 "O".

Mankhwala "Metronidazole"

Antiprotozoal ndi antibacterial wothandizila ntchito zosiyanasiyana za mankhwala. Anaikidwa kukhala mu matenda protozoan, matenda zimfundo ndi mafupa, ndi matenda m'mimba ya etiology bakiteriya. Yopangidwa yogwira mankhwala mlingo njira zinayi zikuluzikulu: mu mawonekedwe a gel osakaniza ukazi, kulowetsedwa njira, suppositories ndi miyala.

Izi analogue 'ndi chloramphenicol' kuchokera m'mimba ayenera kugwiritsidwa ntchito pa mankhwala, amene adzaika Kutalika kwa Inde achire ndi mlingo. Apo ayi, chiopsezo zosiyanasiyana chokhwima kwa thupi kumawonjezera kwambiri. Pankhaniyi, chapakati mantha dongosolo amavutika ndi odwala amadandaula omangana, kupweteka kwa mutu, kutopa, kusowa tulo, chizungulire, irritability, kugona, ataxia, chisokonezo ndi ngakhale kuyerekezera zinthu m'maganizo. Komanso, palokha kutenga mankhwala akhoza kuvutika alili, ikuthandizira m'mimba. Lusoli kuoneka kusanza, kudzikayikira dryness mkamwa, imfa wathunthu wa kudya ndi matenda ena a dongosolo m'mimba. Choncho, monga njira "Chloramphenicol" malangizo ntchito analogues amalimbikitsa kutenga yekha mankhwala. Izi zingathandize kupewa zochita osafunika mbali mwamsanga kuthana ndi vuto alipo.

Amatanthauza "Ciprofloxacin"

Wina analogue a "ndi chloramphenicol" - mapiritsi "Ciprofloxacin". mankhwalawa ali ndi zotsatira antibacterial ndi yogwira motsutsana tizilombo toyambitsa matenda a matenda ambiri a dongosolo genitourinary ndi kapepala m'mimba. Mlingo wa mankhwala ndi nthawi ya njira achire kuchita masamu payekha.

Mankhwala si analogi structural amatanthauza "Chloramphenicol", koma pharmacological katundu wa awa awiri mankhwala ofanana kwambiri. Komanso, iwo akhoza kugwiritsidwa ntchito pa matenda otsekula m'mimba chifukwa cha tizilombo zosiyanasiyana tizilombo. Pankhani contraindication ntchito antibayotiki "Ciprofloxacin" kuti ambiri a iwo. Choyamba, izo koletsedwa mankhwala amagwiritsidwa ntchito pofuna kuchiza ndi ana amene alibe atapeza zaka khumi ndi zisanu. Kachiwiri, ali osavomerezeka ntchito mankhwala kwa akazi pa mimba ndi mkaka wa m'mawere. Chifukwa chake kuti analogue a "ndi chloramphenicol" ndi nthumwi ya mndandanda quinolone mankhwala amene angathe kudziunjikira mu mafupa ndi minofu chichereŵechereŵe kuwononga dongosolo lawo. Ndipo ndi choopsa kwambiri kwa nyenyeswa wosabadwa komanso kwa mwana amene amayi ndi yoyamwitsa.

Mankhwala "Amoxicillin"

Wina mankhwala antibacterial, amene mwangwiro lasonyeza mankhwalawa matenda matumbo kuti amayambitsa kutsekula m'mimba, ndi njira "Amoxicillin". Monga mankhwala "Chloramphenicol" analogues wa ayenera kugwiritsidwa ntchito kokha wauzidwa ndi achipatala. Ndipotu, ambiri mankhwala ndi mavuto. Choncho, kupatsa kwa wodwala wothandizila antibacterial, katswiri osati linaŵerengera mlingo wa mankhwala, komanso kukhazikitsa malamulo chikuonetseratu. Amagwiritsidwanso chofunika monga mu mankhwala zovuta za probiotics kuti akhoza kuchepetsa zotsatira zoipa nthumwi antibacterial ndi kukhala zachilendo zomera matumbo.

Analogs "ndi chloramphenicol" ana

Ngati kutsekula wayamba mu mwana ndikuvala - osati njira yabwino yothetsera vutolo. Ndipo osanenapo ntchito osadalira pa nthumwi antibacterial ndi alibe. Chinthu choyamba kuchita ndicho kuona katswiri thandizo. The dokotala zifotokoza nyenyeswa, adzakangamira mndandanda wa maphunziro ndi mankhwala abwino wodwala mankhwala pang'ono. Kumene, ngati anatsimikiza kuti otsekula m'mimbawa ndi tizilombo toyambitsa, chithandizo popanda mankhwala silingakhale zotheka. Koma zimenezi sizikutanthauza kuti a dokotala mankhwala monga "Chloramphenicol". Analogs ana osankhidwa malinga ndi gulu m'badwo wa mtima, kukula kwa matenda, komanso mogwirizana ndi makhalidwe munthu zakugwa (ziwengo, tsankho ndi mankhwala ena ndi mbali zawo, matenda aakulu, ndi zina zotero. D.).

Nthawi zambiri mu Zikatero, ndi kupanga mankhwala "nifuroxazide," kutanthauza gulu la nitrofurans. Lilipo monga piritsi mawonekedwe ndi kuyimitsidwa, izi analogue "chloramphenicol." Miyalayo zambiri Kwalamulidwa kwa achikulire ndi ana a zaka sukulu, koma mu madzi mawonekedwe zikutanthauza mungapereke nyenyeswa.

Kuposa m'malo mankhwala pochiza matenda a maso?

Poganizira katundu wa mankhwala "Chloramphenicol" ndi analogues ake, Tisaiwale kuti mankhwala antibacterial chimachitika m'njira zosiyanasiyana ndipo angagwiritsidwe ntchito m'madera angapo mankhwala. Mwachitsanzo, madontho diso ankagwiritsa ntchito mchitidwe ophthalmologic zochizira matenda oyamba ndi bakiteriya matenda. Nthumwi angathe kuperekedwa kwa odwala matenda conjunctivitis, blepharitis, keratitis, uveitis ndi matenda ena.

Komabe, ngakhale efficacy mkulu, mankhwala sangathe analimbikitsa onse, monga mndandanda wa contraindications ku phwando ake ndi okwanira. Malinga ndi mfundo malangizo kugwiritsa ntchito, medicament ndi kutiletsa ndi ana osaposera zaka 18 a akazi zaka, pakati ndi unamwino. Odwala matenda a dongosolo hematopoietic, aimpso kapena kwa chiwindi insufficiency ndi matenda ena zokhudza zonse ndiponso kugwiritsa ntchito mankhwala "Chloramphenicol" (diso madontho). Amene ali ndi zosakaniza otetezeka mu zoterezi - yekha zolondola njira kwa kuthetsa vutolo. Malinga m'badwo wa mtima kwakukulu ndi matenda, adokotala angakulangizeni madontho monga "sulfacetamide", "Okomistin", "Normaks", "Floksal" ndi ena.

Mankhwala "Albucidum"

Monga mankhwala "Chloramphenicol" (m'malovu), ndi analogue "sulfacetamide" ndi medicament okhala zotsatira bacteriostatic. Izi mankhwala Kwalamulidwa kwa odwala - amisinkhu -. Pakuti kupewa ndi kuchiza matenda yotupa matenda diso monga keratitis, conjunctivitis, blepharitis, etc. Chinthu chokha chimene m'pofunika kulabadira popeza kuti zochizira ana ntchito 20% ya mankhwala kusungunuka koma magulu zaka akulu amasonyeza 30%.

Ngati tikambirana zotsatira zotheka mbali ya mankhwala, kawirikawiri, iwo zimachitika kawirikawiri ndipo sanafunikire chithandizo symptomatic.

Kodi mukufuna kudziwa za mankhwala "Chloramphenicol" ndi analogs ake?

Mankhwala ofanana mu dongosolo kuti njira "Chloramphenicol", osati kwambiri. Koma pano pali mankhwala ndi katundu zofanana pharmacological ziri zoposa mokwanira, ndi tichisankhe - ayenera kutsimikiza mtima potsatira dokotala. Only katswiri, amene wakhala matenda ndi kudziwa kukula kwa matenda ndi etiology ake, angakulangizeni kuti wodwalayo maofesi phwando "Chloramphenicol".

Analogs (m'mimba, mwachitsanzo) mu mawonekedwe a miyala ndi kuyimitsidwa, nayenso, ayenera kumwedwa pa malangizo a dokotala, bwino kutsatira dongosolo dosing. Izi kuchepetsa chiopsezo mavuto.