Zamchere phosphatase - yofunika enzyme thupi

Pakali pano, matenda zovuta matenda ambiri ntchito njira zasayansi kulipenda. Zimenezi zimaphatikizapo ndi kusanthula amuzolengedwa magazi.

Zamchere phosphatase: onse makhalidwe a enzyme ndi

Zamchere phosphatase - mmodzi wa zizindikiro zofunika kwambiri. pawiri Ichi ndi puloteni omwe akusonyeza ntchito phosphatase. Mwa pafupifupi maselo onse a anthu. ntchito zake pazipita zikusonyezedwa sing'anga ndi zamchere ndipo amagwirizana ndi nembanemba selo. Ndende apamwamba pawiri imeneyi inalembedwa osteoblasts (maselo mu minofu fupa), maselo chiwindi ndi tubules aimpso mu mucosa m'mimba, komanso latuluka. Zamchere phosphatase, amene ali seramu, monga ulamuliro, anachokera ku fupa kapena hepatocytes. ntchito yake yapamwamba zimawonedwa makamaka matenda chiwindi zimene zimachitika ndi kutsekeka kwa ya ndulu ritsa, komanso zotupa fupa ali limodzi ndi fupa kukonzanso.

Zamchere phosphatase msinkhu ndi mkulu. Chifukwa chiyani?

Pali ambiri matenda limati imene kuchuluka phosphatase zamchere. Ponseponse pa chizindikiro ichi zimadalira msinkhu ndi kugonana, kotero kutenga zimenezo akamamasulira magazi sayansi.

Zina mwa zinthu etiological zomwe zingakhudze mlingo wa michere, kuphatikizapo phosphatase zamchere, muyenera kukhala otsatirawa:

• mimba;

• Postmenopausal;

• osakwanira wambiri kashiamu zakudya, ndi phosphates;

• owonjezera ascorbic asidi thupi;

• ntchito wothandizila umodzi pharmacological (mwachitsanzo, kulera munali esitirojeni ndi progesterone, komanso mankhwala).

Komanso, zamchere phosphatase akhoza zochuluka matenda otsatirawa:

• hyperparathyroidism;

• mtima impso kapena minofu m'mapapo;

• myeloma angapo;

• matenda mononucleosis;

• matenda a mafupa, monga khansa ya chibadwidwe;

• matenda Hodgkin, amene amapezeka ndi chiwonongeko cha fupa;

• rickets;

• zilonda chotupa pa mundawo biliary;

• kutupa chikhalidwe opatsirana komanso matenda a chiwindi, kugonjetsedwa kwake TB.

Etiology kuchepetsa phosphatase zamchere

Pali zingapo pathologies imene M'malo mwake, zamchere phosphatase yafupika. Choncho, mlingo wa enzyme m'munsimu yachibadwa mu hypothyroidism. Kulakwila kukula fupa, akusowa nthaka ndi magnesium, komanso magazi m'thupi - zinthu etiological zomwe zingakhudze kuchuluka kwa phosphatase zamchere mu seramu magazi. Mukumwa mankhwala komanso kusintha zotsatira mayeso. Komanso, pamaso pa chiseyeye, amene akufotokozera chifukwa insufficiency asidi ascorbic akutitsogolera kuti kuchepa kwa enzyme ndi.

Tikumbukenso kuti mimba zamchere phosphatase akhoza kukula ndi kuwonjezera chiwerengero cha isoenzyme placental. Izi ndi zina mwa gawo lotsiriza la mimba ndipo amagwirizana ndi chitukuko pazipita latuluka lapansi. Chotero chitsanzo alibe phindu matenda, choncho sichiri mumayesto boma la mayi kapena mwana wosabadwayo. Nthawi pamene mkazi matenda placental insufficiency, ndende pawiri izi yafupika enzyme.

Features cha kusintha kwa mlingo wa phosphatase zamchere

Zamchere phosphatase ndi mu mawonekedwe a isoenzymes angapo. Mlingo wa kuwonjezeka mu ndende pawiri la chilamulira chikhalidwe ndi osteoblastic yogwira (fupa mapangidwe ndondomeko), kotero kuti mlingo wokweretsa fupa isoenzyme anati matenda Paget a. Ngati wodwala akufotokozera kudwala ntchito osteolytic (mwachitsanzo, angapo myeloma), ndi zamchere phosphatase kuwonjezeka, koma pang'ono chabe.

Pamene zotupa a dongosolo hepatobiliary kumawonjezera kwa chiwindi isoenzyme. Zochita matenda, amagwiritsidwanso ntchito ngati chikhomo cha cholestasis. Pankhaniyi, imfa mwachindunji maselo chiwindi zichitike ndi maziko a misinkhu labwinobwino kapena ngakhale otsika phosphatase zamchere. chitsanzo ndi zina, monga ulamuliro, chifukwa nthawi zambiri matenda, ngakhale sangathenso anati mu mtima munthu, ngakhale ndi kuwonongeka kwa chiwindi kapena kapepala biliary.

Dziwani kuti kuchuluka phosphatase zamchere mwana - chodabwitsa thupi, amene amagwirizana ndi kukula amphamvu. Choncho, mlingo wa puloteni imeneyi ana akhoza kufika pamlingo umene umaposa ponseponse kwa munthu wamkulu nthawi 1.5-2 (kwa 82 kuti 341 U / L).

Kulunjika kudziwa mlingo wa phosphatase zamchere

Pakali pano, zikhalidwe mulingo woyenera kusanthula pa mtima wa anthu ambiri phosphatase zamchere ndi osiyana, chifukwa aliyense zasayansi ali ndi mfundo zake. Pali njira zingapo zofufuza zomwe zimadalira gawo lapansi enzyme ndi dongosolo gawo lotetezedwa komanso kutentha pa zomwe zitsanzo anangokhala. Yunifolomu malire chizindikiro "zamchere phosphatase" si choncho Sikuti kuyerekeza makhalidwe a enzyme, amene zimapezeka mu Laboratories osiyana. Izi ndi zoona makamaka samadziwika zimene amalamulira Laboratories amenewa.

Yoganizira za seramu magazi ntchito. Nthawi zambiri, kutenga pamwamba wosanjikiza, amene anapanga mu olekanitsa chubu. Dziwani kuti mlingo wa phosphatase zamchere akhoza olakwa kuchuluka, ngati mwazi zitsanzo zosankhidwazi tourniquet pa nthambi chapamwamba wakhala adaachitumiza kwa masekondi oposa 30. Komanso, ntchito ya enzyme izi zingasiyane pang'ono ngati chitsanzo magazi kusungidwa firiji. Ichi mu m'galasi hemolysis sikumangotikhudza zotsatira mayeso.

Kodi kuchita pamene mlingo pathological wa phosphatase zamchere?

Pamene zamchere phosphatase kuchuluka, mankhwala ayenera kukhala etiological malangizo. Motero, kukhalapo kwa chiwindi kapena biliary matenda ayenera kuonana ndi gastroenterologist. Cholestasis, pamaso kapamba, mowa chiwindi kapena matenda enaake amafuna lolingana kudzudzulidwa mankhwala amene buku anatsimikiza yekha ndi dokotala. Self Pankhaniyi zingachititse kuti aggravation matenda choyambirira.

Kusintha ndende ya michere, kuphatikizapo phosphatase zamchere, akhoza anaona zoopsa mtima, khansa kudwala ndiponso kuwonongeka kwambiri kwa impso, komanso matenda a shuga, kotero muyenera kukaonana ndi cardiologist, nephrologist kapena m'thupi yemwenso. adokotala kudziwa machenjerero achire malingana ndi chithunzi matenda.

Pochotsa zinthu etiological, zamchere phosphatase ntchito akubwerera mwakale. Poika mankhwala ayenera n'komwe kuti Mwachitsanzo, kuwonjezeka thupi la chizindikiro zimenezi ndi fractures, kukula yogwira dongosolo chigoba, ndi gestation. Izo sikutanthauza alowererepo zachipatala. Kutanthauzira kwa zotsatira za mayesero zasayansi ayenera idzachitika comprehensively, kutenga nkhani zina magawo amuzolengedwa ndi madandaulo mtima.