Yisiti ngati bowa wa mtundu candida

Chotero dziko limene aliyense wa ife wazunguliridwa ndi zikwi za zolengedwa zing'onozing'ono. ndife apoyera sitingawaone, koma kulowa nawo miniti iliyonse. Ena "wosaonekayo" atithandize, ena aphedwa, ndipo ena akhoza kubweretsa, ndi mavuto ndi phindu. Yisiti ngati bowa wa mtundu candida ndi zoterezi tizilomboto kuti sizimathandiza kupewa kuti tikhale ndi moyo mosangalala mpaka kalekale, koma ku zinthu zina kuyamba kuchita zinthu azitengapo, kuchititsa matenda candidiasis kapena thrush. Chifukwa zamoyo izi si nthawi chabwinobwino, iwo amatchedwa osiyanasiyana. Total anatulukira mitundu 186 ya bowa wa mtundu candida, koma kuopsa kwa mitundu iwiri yokha khumi. Pa iwo ayankhidwa m'nkhaniyi.

The mtundu candida bowa: makhalidwe

Candida yisiti wachokera ku mtundu wa. The ambiri mitundu ndi chabwinobwino kwathunthu ndi moyo mu thupi la bowa tiyi yogurt, zakudya zina za mkaka, komanso mu kapepala m'mimba wa munthu, kusonyeza mbali ya zomera wathanzi m'mimba. Bowa wa mtundu candida ndi thupi, mwachitsanzo, ndi achangu mu kukhalapo kwa mpweya. Iwo akhoza kukhalapo m'njira ziwiri - yisiti ndi micellar. Mu yisiti bowa ndi zozungulira kapena chowulungika budding blastospores ndi chulukanani. The micellar mawonekedwe maselo mafangasi elongate, osatembenukira ku pseudomycelia. Mosiyana ndi zoona, palibe partitions, koma pali constriction. Iwo zili blastospores, ndi expansions osachiritsika hlamidiospory awiri Khoma. Mawonekedwe micellar wa bowa amatha amamuchitira.

zolengedwa zina dimorphic bowa wa mtundu candida ndi osiyana mu kuti akhale mu thupi la mbuye wake awiri mwa mtundu uliwonse, koma osati kusintha iwo malingana ndi kutentha yozungulira.

An chuma chofunika wa candida - amatha kupesa maltose ndi shuga.

matenda Candidiasis, malinga ndi kafukufuku wa posachedwapa, chifukwa cha mitundu pafupifupi 20 bowa, ndipo ndi C.Albicans owopsa (60%) ndi C.Tropicalis (20%). Otsala 18 mitundu ya inafalitsidwa mvetsetsa zazing'ono pa zochitika za candidiasis mulibe.

Mwachidule DESCRIPTION mitundu tizilombo

The bowa zambiri anakumana za mtundu candida, wotchedwa C.Albicans. onyamula awo pafupifupi 8 10. ambiri bowa awa kulowa m'thupi mwana pobadwa ndi moyo popanda ovutitsa, mu m'kamwa zibowo zam'mano, kum'mero ndipo matumbo. Mu akazi, nawonso ali m'gulu la microflora ukazi. Ndi mtundu uwu wa candida zambiri udindo pakutchulidwa wa candidiasis.

Mtundu wachiwiri amatchedwa oopsa C.Tropicalis. bowa awa angathe kulowa mu magazi ndi ntchito kuti azikakhala ziwalo zotumphukira. maphunziro Recent ndakufotokozerani mbali ya candida C.Tropicalis ntchito mu tandem ndi Serratia marcescens ndi Escherichia coli, ndi chifukwa cha matenda amene amatupitsa.

Osati sizachilendo, koma amaonedwa kukhala bowa yoopsa kwambiri ya mtundu candida yisiti mitundu C.Krusei. Iwo kugonjetsedwa ndi mankhwala "Fluconazole", ntchito pa matenda a matenda a mafangasi, kotero ndikofunika kusiyanitsa mtundu wa tizilombo bowa kuvutitsa mtima.

Bowa candida mitundu C.Glabrata ankaona sanali tizilombo. Iwo unalipo mu mawonekedwe yisiti ndi kubereka budding yekha. Nthawi zambiri, candida Glabrata wapezeka pa catheters mkodzo, kumene ndipamene biofilm woonda. bowa Izi zimapangitsa urogenital candidiasis.

Candida mitundu C.Parapsilosis kawirikawiri chifukwa cha sepsis. Iwo amatha wa matenda pabalapo, makamaka ngati zinthu zakunja mwa iwo.

Species ya bowa ndi C.Rugosa C.Lusitaniae ndi ena a mtundu candida n'zochepa kwambiri. Mwachitsanzo, C.Lusitaniae mu nthawi kuchokera 1979 mpaka 1990 anali wapezeka kokha odwala 30.

Njira kachilombo

Salembedwa - tizilombo yisiti bowa wa mtundu candida m'kupita kwa kusanduka apanga njira zimene zingawathandize kukhala kuli parasitic. Iwo amatha kupirira yaitali yozizira koopsa ndi kuyanika. Lowani thupi la munthu, iwo akhoza kukhala wauve ndi bwino kukonzedwa chakudya ndi manja zauve ndi zinthu zina, monga bowa C.Parapsilosis kupatsira mabala ndi kusalola zinthu zakunja, kuphatikizapo komanso chosawilitsidwa zida zamankhwala ndi bowa C.Glabrata ndi mkodzo kapena mtsempha catheters. Nthawi zambiri kukhala ali ndi bowa mitundu C.Albicans, ndi mphindi zoyambirira za moyo mwana. Izi zimachitika pobereka, ngati amayi nyini ndi lidzaze ndi majeremusi izi. Palinso nkhambakamwa kuti C.Albicans alowa m'thupi mwana adakali siteji Ndisanaumbidwe, chifukwa bowa wa mobwerezabwereza linapezeka madzimadzi amniotic. Ngati mkazi wakubala ndi mbali ya ochepa a anthu amene sali onyamula bowa, mwana wake pa zaka zoyambirira za moyo kuwatenga iwo mwa nipple, zidole ndi zina zotero. Mantha chifukwa izi si koyenera, chifukwa candida, kamodzi mu thupi la khamu ake, sichichita mwakachetechete, ngakhale kumuthandiza kulamulira kukula kwa tizilombo toyambitsa matenda ena.

Pamene bowa candida matenda amakhala matenda

Munthu atha kukhala chonyamulira cha majeremusi moyo pamene otsala wathanzi kwathunthu. Bowa wa mtundu candida kukhala tizilombo kokha pamene kuchuluka kwawo akupeza kulamulira. zifukwa:

- mimba;

- matenda osiyanasiyana;

- exacerbation la matenda aakulu;

- hypothyroidism kapena vitamini akusowa;

- yaitali chithandizo ndi mankhwala;

- corticosteroids;

- m'thupi matenda.

Chifukwa chachikulu kuti chimachititsa candidiasis, ndi chitetezo chokwanira otsika. chikhalidwe ichi angayambe zinthu zambiri, kuphatikizapo zakudya m'thupi, zinthu osauka moyo, maganizo pafupipafupi.

Komanso kukula mwadzidzidzi bowa candida kumachitika pamene zotsatirazi matenda concomitant:

- AIDS (kapena matenda HIV);

- shuga;

- chifuwa chachikulu;

- matenda m'mimba;

- matenda a dongosolo genitourinary;

- hypothyroidism;

- Ena matenda magazi;

- vaginosis.

zinthu pathogenicity

Makulidwe wa bowa mtundu candida ndi microns 2-5 okha, choncho tinganene kuti yekha pansi simungathe kutiona. Zoyera kapena chikasu greyish plenochki kuti kukula pa Hagara kapena zolengeza kuti kumaoneka pa m'madera okhudzidwa za thupi - ichi ndi madera lonse wa bowa, analipo masauzande tizilombo payekha. Kamodzi pa khamu lake, khalidwe la bowa wa mtundu candida? Microbiologists kafukufuku anasonyeza kuti aliyense bowa amayesetsa kukhala guluu wolimba, ndiko kuti, pafupi amamuchitira, munthu anganene, kukula mu maselo a anthu zaminyewa. Iwo tizilomboto kusamalira mosavuta m'munsi chitetezo chokwanira ya adani awo, ndi apamwamba endocrine matenda ake. Mbali achangu wa zowalamulira bowa mitundu C.Albicans. Kamodzi pa nembanemba wa mucous, limayesetsa 100% ya milandu. Ambiri mitundu chabe bowa C.Krusei. Iye sangatichotsere atathana, ndiye palibe matenda. Kuthandiza bowa kudutsa mapuloteni pamwamba ndi mapuloteni pamwamba, ena mamolekyulu, mwachitsanzo, polysaccharides ndi glycoproteins, ndi tinthu m'kamwa malovu. Nthawi zambiri, candida ndi glikogenofilami (glycogen ngati), kawirikawiri colonizes minofu komwe muli zambiri, mwachitsanzo, ndi mucosa ukazi ndi m'kamwa zibowo zam'mano. Mu chochitika cha yisiti bowa wa mtundu candida mu chopaka anatengedwa kuchokera ku ziwalo izi anavumbula Mwina mkulu limene limathandiza matenda zolakwa-free.

Pa siteji yoyamba ya bowa guluu wolimba ndi yisiti mawonekedwe, koma mofulumira kuwayalanso, kupanga filaments yaitali (hyphae), amene savuta kudutsa mu maselo kuonongeka khamu ndi phagocytosis wa leukocytes sachedwa zochepa.

Alimbikitse ndi mbuye, majeremusi pa moyo wawo khamu lake olekanitsidwa ziphe zosiyanasiyana:

- kandidotoksin (mapuloteni zochita pa basophils ndi maselo mlongoti ndi kuchititsa zoyerekeza-response);

- 6 mitundu otsika kulemera poizoni maselo (kuchuluka mtima permeability m'munsi magazi);

- zamadzimadzi poizoni (leukocyte chifukwa zochita m'dera ndi kuyambitsa maonekedwe a granulation minofu).

Candidiasis ana

Monga taonera, makanda ndi kachilombo candida kapena m'mimba kapena pobadwa pa ndime ya ngalande kubadwa. M'tsogolo, bowa akhoza kutenga mwana mkamwa ndi pacifier bwino ankachitira, maseche, ndi teats kachilombo mayi. Zizindikiro kuti mwanayo ankadwala thrush, zotsatirazi:

- woyera, kanyumba tchizi ngati ❖ kuyanika pa lilime, pa mkati pamwamba desenok ndi masaya;

- moodiness;

- kukana chakudya.

Popanda mankhwala, bowa akupitiriza kuthetsa ndipo posakhalitsa amapezeka pa milomo ya mwanayo.

Bowa wa mtundu candida m'matumbo dysbiosis zizindikiro ziwonekera monga:

- m'mimba;

- ulesi;

- kutentha;

- imfa ya thupi.

M'mimba mwa makanda ndi oopsa chifukwa kumabweretsa madzi m'thupi mofulumira, kotero mwana wodwala ku chipatala. Only mu chipatala angapereke iye ndi mankhwala zofunika (kukapanda kuleka) kupewa imfa madzimadzi.

Kuwonjezera pa kapepala m'mimba ndi m'kamwa zibowo zam'mano, thrush ana akhanda uonekere pa khungu. Pankhaniyi, pali woyera, ndi mawanga ofiira ngati thewera zidzolo. Mwana amakhala capricious kwambiri monga erosions aliyense kukhudza chifukwa akuvutika. Nthawi zambiri, cutaneous candidiasis makanda limapezeka m'makwinya pa miyendo, matako ndi groin. Yoyamba ya thewera zidzolo, pokhala matewera motalika kwambiri, ukhondo osauka ndi zosayenera (kupanga, nayenso zolimba) zovala.

Chithandizo cha candidiasis infantile

Ngati bowa wa mtundu candida ndondomeko tizilombo anayamba m'kamwa mwa mwanayo, chithandizo nthawi zonse umachitikira kwanuko. Amakhala mu processing malo kumene woyera film, kukonzekera mwapadera. Poyamba, madokotala zimachitika dzola mafuta pakamwa mwanayo ndi utoto wobiriwira. mankhwala Izi ndi zabwino, koma youma mucous. Tsopano ntchito "Akriderm", "Fukortsin" njira ya borax mu glycerine ndi.

Monga kupewa ndi kofunika mu miyezi ya moyo grudnichka wiritsani nsonga zamabele ndi mabotolo, kuchapa maseche. Amayi kusamalira pamaso kudyetsa nsonga zamabele mankhwala antifungal.

Pamene zizindikiro za dysbiosis chikudutsa ndowe grudnichka pa bakposev. Akukhulupirira kuti bowa wa mtundu candida ndi chopondapo ana osakwana zaka miyezi 12 akhoza kupezeka zedi osati choposa 103KOE / g, ndi miyezi yoposa 12 kuchuluka kwa 104KOE / g. Ngati mtengo uli kuposa, mankhwala mankhwala kuti abwezeretse zomera ndi kulimbikitsa chitetezo cha m'thupi.

Pamene candidiasis khungu anakhudzidwa madera ena a mafuta antifungal topaka - mankhwala a nystatin, levorinovoy. kwambiri kusamba mwanayo madzi ndi Kuwonjezera msuzi motsatizana calendula, chamomile. Onse linens ndi matewera ayenera chitsulo ndi kumusintha matewera zambiri zokwanira, osati kudikira kuti amalize kudzazidwa.

Ngati mankhwala amenewa si kuthandiza mwana wanu amathera kuunikidwa zina ndi mankhwala mankhwala antifungal.

Candidiasis amai ndi abambo

Akuluakulu, candida bowa akhoza, ngati ana, kuwononga pakamwa, khungu ndipo matumbo. Candidiasis akuwonetseredwa mu pakamwa caseous kukhudza zosangalatsa lilime, m'kamwa, m'kamwa, masaya, ndi mbali mkati limodzi ndi zomverera chopweteka. Nthawi zina ulcerate mucous. Candidiasis wa khungu yodziwika ndi mawanga ofiira malo oyamba a bowa (m'khwapa, pansi pa mabere mu akazi, mu groin ndi osachepera pansi maondo). mawanga izi itch ndi peel, pamene kukanda ulcerate. Koma ambiri a akulu onse akudwala ziwalo candida mkodzo. Akazi bowa mphanga mu nyini ndi akumaliseche, kotero nthendayo imatchedwa vulvovaginitis. zizindikiro zake mu magawo koyamba motere:

- woyera (ngati mkaka wowawasa) ukazi kumaliseche;

- kuyabwa, osati kudutsa, koma m'malo mwake, pambuyo kukonza kukula ndi m'mawa;

- zosasangalatsa fungo kabudula;

- Chisoni pa kugonana.

The koposa chizindikiro - bowa wa mtundu candida mu chopaka anatengedwa kuchokera ku nyini.

Popanda mankhwala, zizindikiro ndi poipa. , Ululu osati pa kugonana, komanso pa chilichonse pokodza, ukazi mucosa zitunda, ulcerate, kumaliseche amakhala thicker.

Anthu, matenda amatchedwa candida balanoposthitis. zizindikiro:

- Kugawilidwa kwanthaka wa mtundu wowumitsa ya chiwalo cha kugonana;

- kuyabwa, kupweteka pamene akukodza;

- kugonana chopweteka.

Kuwonjezera dongosolo genitourinary, candida bowa ndi tizilombo pa matupi lakunja la anthu. Nail matenda otchedwa "sekeleti" ndi prinogtevogo wodzigudubuza - "paronychia". Zimayambitsa matenda amenewa akhoza kukhala hangnail, kugwira zozipakapaka kachilombo zida.

Analysis pa bowa wa mtundu candida

Candidiasis wayikidwa potengera zotsatira za maphunziro awa:

- chopaka ku M'mimbamo m'kamwa kapena kumaliseche;

- yodzala;

- Elisa;

- PCR.

Komanso, adokotala akhoza kulamula mayesero a mkodzo ndi magazi.

Ngati mukufuna kutenga swab ku nyini ndi / kapena mkodzo, inu saloledwa kusamba, koma zitha kukodza kwa maola 2 asanadye ndi kuipitsa mbiri, pambuyo pake. Ngati mukufuna kutenga swab pakamwa, izo ndikoletsedwa kuyeretsa mano.

Pakuti kufesa ntchito ndowe, sputum, mkodzo, scrapings ku m'madera okhudzidwa ndi pakhungu nembanemba mucous. Patapita masiku atatu, kupeza yankho, inde kapena ayi mu nkhani ya bowa wa mtundu candida. Wakudziko - ndi negative. Ngati mayesero kutsimikizira pamaso pa bowa ndi tizindikire mtundu wake ndi kudziwa mankhwala.

Elisa kusanthula amatchedwa enzyme immunoassay. Izi zimathandiza kudziwa chitetezo kwa bowa ndi njanji mphamvu ya ndondomekoyi. Zofunika kafukufuku kwa EIA ndi magazi kuchokera mu mtsempha wa. Childs, izo wochititsidwa pamodzi ndi bakposeve.

Amaona molondola kwambiri PCR kusanthula tanthauzo polima-unyolo zimene DNA mamolekyulu wa bowa ndi. Iwo detects kukhalapo kwa tizilomboto ngakhale pa siteji koyamba za matendawa. Nkhani za PCR ndi sputum excretion, magazi.

chithandizo

Ngati wodwala anapeza bowa wa mtundu candida, chithandizo ndi mankhwala. Mkati mankhwala:

- "Fluconazole".

- "Nizoral".

- "Diflucan".

Kunja ntchito mafuta:

- "clotrimazole".

- "Sertokanazol".

- "miconazole".

- Makandulo ndi pumafitsinom ndi njira zina kuti ziletsa kukula kwa bowa. Iwo akhoza anapatsidwa ndipo antiinflammatory mafuta.

Chithandizo cha amayi apakati ikuchitika kudzera kunja. Only mu zina anatumizidwa "Pumafitsin" pakamwa.

Pamene candidiasis urogenital kapepala ndi mankhwala a akazi kugonana.

Komanso mankhwalawa antifungal ndi akuchipatala mavitamini ndi njira zina, kuthandiza chitetezo cha m'thupi.