Methotrexate. Malangizo ntchito

Medicine "Methotrexate" ndi antitumor wothandizira. The medicament mgulu la antimetabolites - kupatsidwa folic muzikangana acid. Mafotokozedwe "Methotrexate" zinaonetsedwa pa chionetserocho ntchito ndi maselo kukula mofulumira. Komanso, mankhwala akhoza kuchita khama ena obwera immunosuppressive.

"Methotrexate". Malangizo ntchito. Zikuonetsa.

mankhwala Kwalamulidwa kwa pachimake lymphatic khansa, Ewing a sarcoma, myagkokletochnoy ndi osteosarcoma, retinoblastoma, nyongolosi khungu zotupa za n'kuwasanganiza ndi testis, matenda trophoblastic, medulloblastoma. "Methotrexate" Malangizo pa ntchito akuonetsa ntchito ndi khansa akumaliseche ndi khomo pachibelekeropo, khungu, kum'mero, ureter ndi mafupa a chiuno aimpso, chifuwa, m'mapapo, impso, chiwindi, penile squamous mutu ndi khosi, komanso ndi mauka. mankhwala akusonyeza kuti nyamakazi, psoriasis ndi mitundu choopsa cha otaya mu pakalibe Ntchito achire zotsatira mankhwala okwanira.

"Methotrexate". Malangizo ntchito.

The medicament ndi mtsempha, m'kamwa, intralyumbalnogo ndi ntchito mu mnofu. The mtanda ali wodwala aliyense payekha. dokotala amaganizira matenda makamaka chikhalidwe cha dongosolo hematopoietic dera antitumor chithandizo.

Ntchito ya mankhwala zingachititse anorexia, stomatitis (anam'peza), gingivitis, nseru, pharyngitis. Nthawi zina, pali enteritis, m'mimba, kapamba, melena. Yaitali tsiku wambiri zikhoza chifukwa matenda enaake, necrosis a chiwindi, mafuta manja, fibrosis a chiwindi periportal.

zosiyanasiyana chokhwima ndi kugwiritsa ntchito mankhwala "Methotrexate" malangizo Buku m'gulu magazi m'thupi, leukopenia, chizungulire, kutopa, thrombocytopenia, aphasia, khunyu, mutu, somnolence.

Nthawi zina, matenda a kuzungulira msambo kumachitika, kusokoneza spermatogenesis, oligospermia, kusabala, utachepa libido.

Odwala ena ndi cystitis, hematuria, matenda aimpso ntchito ya khalidwe, utachepa kukana matenda, malungo, urticaria, epidermal necrolysis poizoni, photosensitivity, zidzolo, abrasions, ziphuphu, telangiectasia.

Contraindicated "Methotrexate" ndi leukopenia, mimba, matenda a chiwindi ndi impso kulitchula. Osavomerezeka chida ndi immunodeficiency. Pamene muyenera kumwa mankhwala pa mkaka wa m'mawere, kudya ayenera anasiya. Chifukwa cha zimenezi, ena maphunziro anakhazikitsa zotsatira teratogenic ndi embryotoxic.

Akazi akafika msinkhu wobereka ayenera kugwiritsa ntchito njira zolera odalirika pamene ntchito "methotrexate".

Analimbikitsa mankhwala kwa chironda chachikulu mu duodenum ndi m'mimba, pleural effusion, ascites, matenda a impso, gout, matenda a m'matumbo (anam'peza).

Odwala katsabola panopa kapena posachedwapa anasamutsidwa, nsungu (nsungu) ndi matenda ena opatsirana pachimake "Methotrexate" sanagaŵiridwe.

Pamaso mankhwala umagwiritsidwa ntchito pa maziko a mankhwala zofunika kulamulira magazi chithunzi (zotumphukira), ntchito za impso ndi chiwindi.

Mu ntchito "Methotrexate" chifukwa nyamakazi kapena psoriasis chofunika kuchita mayeso wamba magazi (zofunikila) kamodzi pa mwezi, zasayansi mayesero ntchito chiwindi, impso - kamodzi pa mwezi kapena miyezi iwiri.

Pamaso atasankhidwa wodwala ayenera kukhala bwino ndi onse amaganiziridwa mawonetseredwe chowawa. "Methotrexate" ndi mankhwala oopsa. Pofuna kupewa mavuto zapathengo ntchito mankhwala ayenera kuunikira dokotala.