"Izoket" Utsi: malangizo Buku, ndemanga, mafotokozedwe, analogues, mtengo

Lero, akatswiri ambiri mankhwala odwala vasodilator utsi "Izoket" prophylactically kapena, ngati n'kofunika, cupping ndi zikwapu. Mankhwala ali yaikulu mndandanda wa zizindikiro zosiyana. Iwo bwino ntchito pa matenda a pathologies mtima, kuphatikizapo kulimbana zinthu pachimake.

mankhwala

Yogwira wothandizila mankhwala kuchokera pectoris angina yodziwika ndi kutchulidwa vasodilating ndi vasodilator katundu. Isosorbide dinitrate kumapangitsa mapangidwe okusayidi asafe mu chamoyo ndipo kumachepetsa zofunikira za minofu mtima mpweya ndi mphamvu, potero kuchepetsa katundu myocardium lapansi. Mogwira amachepetsa kuthamanga mu makope m'mapapo mwanga, amachepetsa magazi kwa atrium lamanja, amachepetsa mtima yamitsempha yamagazi khoma mavuto ndi kucheperachepera kuthamanga diastolic ndi ntchito systolic kuthandiza iwo. Mankhwala alibe mphamvu pa pafupipafupi contractions wa mtima ndipo amawachitira bwino ziwiya ubongo. Komanso angadwale mtsempha wa Dura Mater ubongo ndipo potero kupangitsa kupweteka mutu. Njira chikoka pa kusokonekera kwa otaya inatsekeratu magazi m'dera limene magazi yafupika. Mu CHD (inatsekeratu matenda a mtima) ndi angina chifukwa zochita za mankhwala odwala ndi mwayi kuonjezera ntchito chovomerezeka.

Utsi "Izoket" mofulumira odzipereka kudutsa mucosa m'dera pakamwa, kotero zotsatira za tanthauzo lake lidzayamba pambuyo masekondi 30 ndipo amatenga mphindi 120. Ndiyamika liwiro la nthawi zambiri Kwalamulidwa kwa odwala mpumulo atangochimwa zinthu pachimake.

Fomu kumasulidwa

The mankhwala ndi njira bwino, zomwe ndi colorless ndipo ali ndi fungo mowa. Izo zifika ku mitundu iwiri:

1. Utsi "Izoket" ndi sublingual mlingo. Ndi chimodzi pitani pa dispenser limasuka mu mawonekedwe a madontho ting'onoting'ono mmodzi wa mlingo wake amene wapangidwa ndi 1,25 mg wa yogwira pophika - isosorbide dinitrate ndi zinthu wothandiza: Mowa ndi Macrogol 400. The aerosol zikuchokera ali freon Koma limakhudza mankhwala chabwinobwino chilengedwe. Yopangidwa mu mabotolo mandala 15 ml, ankanyamula mu bokosi ndi dispenser ndi malangizo. Galasi botolo kwa kudina 300 (Mlingo), zimathandiza inu kuwunika kuchuluka kwa mankhwala ndi kukhala m'malo m'nthawi yake.
2. The yothetsera mu mawonekedwe maganizo anafuna infusions. 1 ml kukonzekera izi zili 1 mg wa amafotokozera yogwira isosorbide dinitrate ndi zinthu wothandiza: sodium kolorayidi, hydroxide sodium, madzi. Mmodzi vial - 10 ml ya yothetsera kwa kulowetsedwa. Akupezeka mu makatoni mapaketi zidutswa 10 aliyense.

zikuonetsa

Utsi "Izoket" Akatswiri yoikidwa pa stenokardicheskie kuukira mitundu yonse ndi monga muyeso njira kupewa iwo. Izo analimbikitsanso pambuyo infarction limati, m'mnyewa wamtima infarction mu gawo pachimake, kuwonjezera kulolerana ndi IMS ndi mankhwala a inatsekeratu mtsempha wamagazi kuphipha. Aerosol "Izoket" bwinobwino ntchito ngati mankhwala kwa mtima kulephera mu ventricle kumanzere. Malinga ndi malangizo, yesetsani kuganizira kulowetsedwa Kwalamulidwa kwa odwala pathologies ngati a dongosolo mtima:

• wosakhazikika angina zikuchitika mu chikhalidwe preinfarction kapena yapita m'mnyewa wamtima infarction;
• vasospastic angina;
• m'mnyewa wamtima infarction mu mawonekedwe pachimake, chifukwa cha kulephera kwa ventricle kumanzere kwa mtima;
• inatsekeratu vasospasm pa zikunena opaleshoni;
• mtima kulephera kwa mitundu yonse;
• pachimake kumanzere yamitsempha yamagazi mtima kulephera;
• m'mapapo mwanga edema.

Njira ntchito aerosol ndi

kukonzekera A mu mawonekedwe a kutsitsi sprayed kuti patsekeke m'kamwa wodwalayo, chifukwa izi mwamsanga akulowa mtsempha wa magazi. Aliyense jekeseni amapereka wina ingestion mlingo. Malangizo ntchito amatanthauza njira zosiyanasiyana za ntchito mankhwala, malinga zizindikiro.

Pofuna cupping stenokardicheskie kuukira pamaso adziwitse thupi kapena maganizo nkhawa zomwe zingachititse pachimake, anachedwa kupuma, ndi wodwala amalandira Mlingo 1 mpaka 3 pa intervals wa masekondi 30 pakati jekeseni. Kuwonjezera mlingo popanda kuyang'aniridwa katswiri zoletsedwa.

Pankhani ya amaganiziridwa exacerbation kulephera mtima kapena m'mnyewa wamtima infarction, pachimake pa mtima amalandira Mlingo 1 mpaka 3 pansi ziyang'aniridwe ndi mlingo mumtima ndi magazi. Ngati palibe kusintha, ndiye ndondomeko akubwerezedwa mphindi zisanu kenako ndi chisankho ya dotoloyo. Mu mphindi khumi yotsatira, chikhalidwe ayenera ziziyenda. Apo ayi, mukhoza kubwereza mpheto ya kamodzinso kuyang'aniridwa ndi dokotala.

Pamaso mankhwala ndondomeko cupping inatsekeratu kuphipha (kwa kapena yochizira matenda catheterization) kutumikiridwa kwa wodwala jekeseni 1-2. Pamene panafunika mlingo Mungathe kubwereza, koma pokhapokha ngati magawo ulamuliro wa magazi.

ayamikira enieni kugwiritsa ntchito kutsitsi ndi

Nthawi pamene kutsitsi latsopano umagwiritsidwa ntchito kwa nthawi yoyamba, kapena pambuyo mlingo otsiriza wakhala maola oposa 24, izo m'pofunika kulongosola atolankhani choyamba mu mlengalenga, chifukwa simungakwaneko mlingo chofunika. Pakuti Mlingo mogwirizana ndi malangizo nebulizer mosalekeza anakakamizidwa mapeto, ndipo kenako anamasulidwa. Pa ntchito ndi dispenser kutsitsi botolo ayenera kukhala upwardly ndi vertically. Samalani ndi kupewa akukhavukira mu maso. Pa nthawi chithandizo lonse amafuna ulamuliro nthawi zonse magazi (BP) komanso ECG likhale. Mtengo wa magazi sayenera zosakwana 100 mamilimita Hg. Art. Mwadzidzidzi achire wa mankhwala yoletsedwa malangizo, kotero mlingo yoikidwiratu yafupika pang'onopang'ono. mowa ali osavomerezeka tikadwala aerosol "Izoket".

akatswiri Reviews akusonyeza kuti apamwamba mlingo wa mankhwala, nthawi zambiri poika kapena ntchito m'ndondomeko kungachititse kuti kulolerana chitukuko mu mtima. Mbali otere anayamba ndi kugwiritsa ntchito mankhwala ena amene wapangidwa ku feteleza. Zikatero, madokotala amalangiza kuletsa kugwiritsa ntchito mankhwala kwa masiku 2-3, ndipo pambuyo njira ya chithandizo zonse, zomwe masabata 3-6, yopuma kwa masiku 3-5, ndipo m'malo moyembekezera ndi mankhwala ena ndi mavuto ofanana. Nthawi zambiri, pambuyo pa kusokoneza kapena discontinuation tilinazo wodwala m'malo mofulumira anabwezeretsedwa. zikutanthauza zigawo anachokera metabolites monga impso pafupifupi zonse.

Mlingo ndi ntchito njira

Malinga ndi zofunikira mu malangizo kukonzekera "Izoket" (njira yothetsera kulowetsedwa) umagwiritsidwa ndi m'nsinga. Mlingo wa vrechom amachitira payekha zogwirizana ndi hemodynamic ndi magawo matenda a wodwalayo. Therapy ayenera kuyamba ndi mlingo wochepa ndi kukula pang'onopang'ono kubweretsa kwa ndalama chofunika. Malangizo analimbikitsa mlingo ndi 2-7 mg / hr, motero, mlingo avareji za 7.5 mg / hr. Mu milandu kwambiri buku kufunikira akhoza ziwonjezeke kwa 10 mg / hr.

Nthawi zambiri, anthu ndi matenda a mtima amafuna mlingo waukulu wa mankhwala. Mawu oyamba a mankhwala ayenera kukayezetsa mankhwala inpatient kuyang'aniridwa ndi katswiri ndi ntchito machitidwe zodziwikiratu kwa kulowetsedwa. Ndondomeko lonse limodzi ndi makope kulamulira zizindikiro (magazi ndiponso kugunda kwa mtima).

A njira yothetsera makonzedwe mtsempha linakonzedwa mu wosabala asanalankhule ndondomeko. Mankhwala si kusungidwa maola oposa 24. njira kukonzekera:

• kuti ndende ya 0.01% (100 micrograms / ml) - 50 ml ya 0,1% mankhwala akhoza kupanga 500 ml lokonzekera kukonzekera utsogoleli;
• kuti ndende ya 0,02% (200 micrograms / ml) - 100 ml ya 0,1% njira ya mankhwala zingabweretse 500 ml ya medicament kukonzekera utsogoleli.

Contraindications ndi kusamalitsa

Mankhwala si anasonyeza odwala hypersensitive kuti mankhwala nitrate, komanso zinthu zina za aerosol "Izoket". ntchito nazonso zoletsedwa ngati wodwala matenda:

• hypotonia, limene kuthamanga systolic ndi pansipa 90 mamilimita Hg.
• mtima insufficiency mu gawo pachimake, mwachitsanzo, panthawi mantha kapena mtima kugwa;
• pericarditis ndi pericardial tamponade;
• mu cardiogenic mantha pa nthawi imene palibe kuthekera kusintha zina njira kuthamanga mu ventricle kumanzere kwa mtima;
• hypertrophic cardiomyopathy;
• kutsekedwa khungu.

Komanso, mankhwala si anasonyeza kuti anthu osakwana zaka khumi ndi zisanu ndi zitatu zakubadwa. Malangizo ntchito akuonetsa ntchito mankhwala ndi kusamala kwambiri ndi moyang'aniridwa nthawi zonse Zikatero:

• m'mnyewa wamtima infarction ndi nthenda yotaya pachimake pamene wodwala ali ndi kuthamanga yafupika anasiya mtima ventricle kudzazidwa;
• kuthamanga intracranial;
• mitral ndi / kapena kung'ambika stenosis;
• kupeza pakutchulidwa Mwina wa matenda mtima orthostatic mu lamulo la magazi;
• aimpso kapena chiwindi kulephera.

Mimba ndi mkaka wa m'mawere

Asayansi ku chitukuko cha maphunziro mankhwala nyama akhala akufufuza. The kuyesera mayeso inasonyeza kuti zopweteka wosabadwa si anachita. Komabe, pa mimba ndi mkaka wa m'mawere nthawi poika aerosol ndi bwino kokha mu zochitika kumene ubwino anafuna kuti akazi adzakhala kwambiri kuposa chiopsezo kuthekera kwa mwana wosabadwayo kapena amayamwitsa mwana. Chithandizo mu milandu ayenera idzachitika kuyang'aniridwa okhwima akatswiri, magawo makope ulamuliro (magazi ndi mtima mlingo kugunda), komanso chikhalidwe ambiri wodwala.

Mogwirizana ndi mankhwala ena

Ndi zoletsedwa kugawana vasodilators ndi "Izoket" kukonzekera (kutsitsi). ntchito zawo limodzi zingachititse kuchuluka zotsatira hypotensive. Zotsatira chomwecho kumatanthauza munthawi yomweyo phwando "Izoket" ndipo ngati mankhwala aerosol: antihypertensives, blockers kashiamu njira, "Quinidine" kapena "novokainamid" neuroleptics, 5-phosphodiesterase zoletsa.

Kwambiri zotsatira antianginal pamene ntchito limodzi ndi mankhwala monga "Amiodarone", "propranolol", "Nifedipine", "Verapamil," ndi blockers ena a kashiamu njira pang'onopang'ono.

Kuchuluka intracranial kuthamanga wodwalayo angayambe pa kuphatikiza mankhwala ndi atropine ndi zina mamita-holinoblokatorami.

Kugwiritsa kuchepa magazi, zikubweretsa perfusion inatsekeratu limapezeka mchikakamizo cha alpha-blockers ndi sympathomimetic.

Zotsatira zoyipa za mankhwalawa ndi ndemanga

The malangizo anafotokoza zambiri mavuto kuti mwina chifukwa cha mankhwala "Izoket" (kutsitsi). Ndemanga za ena odwala kuchizidwa ndi mankhwala, kusonyeza maonekedwe a mutu, amene mankhwala otchedwa "ku feteleza". Monga ulamuliro, atapita masiku 2-3 vuto Mwamsanga lokha ndi sikutanthauza uphungu. M'malo mocheperapo medicament zikhoza zochitika monga nseru, redness a khungu, kusanza ndi pakamwa youma. Ena odwala amene mankhwala kwa nthawi yoyamba, kudandaula za kufooka ambiri, chizungulire, utachepa magazi ndi kuchita ulesi. Izi zimachitika chifukwa cha zipolowe yaing'ono kugwira ntchito dongosolo mtima. Yak ntchito yaikulu kapena kuposa mlingo analimbikitsa.

Komabe, malinga ndi ndemanga, odwala mutazindikira ndi lapamwamba. Ndipo pamene kulandira malinga ndi malamulo a akatswiri mavuto sanalembedwepo kaŵirikaŵiri. Kupatulapo ndi mutu m'masiku oyambirira a ntchito, zomwe umabweretsa ambiri milandu, koma zambiri akudutsa mu masiku pang'ono.

Idamva buku pazipita

An ambiri osokoneza mankhwala zingachititse zingapo zolakwika kwambiri: syncope, kugwa, mkulu intracranial kuthamanga, hyperthermia, khunyu, matenda zithunzi ntchito, chodziwa thukuta, methemoglobinemia, bradycardia ziwalo, ndi chikomokere. Ndicho chifukwa chake kuli kofunika kuti kudziletsa mtima, ndi kutenga mankhwala mosamalitsa malinga ndi zofunikira za katswiri!

Ngati zizindikiro anafotokoza amafuna kuchotsa mankhwala komanso akuchititsa mankhwala umalimbana ofunika alili.

analogs

Medicament "Kardiket» (CHWARZ PHARMA, Germany) - mmodzi wa mankhwala ambiri omwe angaperekedwe (analogs) wa mankhwala "Izoket" (kutsitsi). Mtengo wa wogwirizira izi amadalira ndende ya mankhwala yogwira ndi chiwerengero cha mankhwala mu phukusi.

Mwachitsanzo, nthumwi mapiritsi a 20 mg wa "Kardiket achigonjetse" (20 ma PC. Pa phukusi) ndi ku rubles 62 mpaka 72, pamene yokonza imodzi, pa mlingo wa 40 mg ndi kuchuluka kwa ndalama 50, ali ndi ubwino 210-220 rubles.

Gulu la mankhwala "Nitrosorbid" chopangidwa ndi makampani akuluakulu Russian, ndi kukhala zosiyanasiyana kumasulidwa, nayenso, ndi mankhwala wogwirizira "Izoket". Analogues wa gulu ili ndi dzina "Nitrosorbide-Rusfar", "Nitrosorbide", "Nitrosorbide NS", "Nitrosorbide-UWI."

mtengo wa

Mu pharmacies Russian kulipira kwa rubles 365 kwa 470 pa mlingo chiphunzitso "Izoket" (kutsitsi). mtengo aumbike malingana ndi malo kubwereketsa ritelo ndi udindo wake. Pa Websites kuti kugulitsa mankhwala zikhoza kugulidwa pa mtengo wotsika kuposa mankhwala ochiritsira pafupi ndi kwanu. Koma pamene kulamula pa Intaneti kulipira 200 rubles yobereka kapena kulandira wothandizila ufulu ndime wakale, amene si nthawi zonse zinamangidwa mwachirengedwe.

Komanso, pa mankhwala alionse mukhoza kugula phukusi (10 Mbale) anaikira njira yothetsera kulowetsedwa "Izoket". mtengo wake umasiyana 906-980 rubles.

mwachidule

mankhwala amapangidwa kampani German "YUSB Pharma GmbH". Alumali moyo wa zaka zisanu. Terms of zogulitsa - kukhalapo kwa dotolo dokotala. Pambuyo nthawi yaitali ntchito izo tikulimbikitsidwa kuti aletse ntchito ya sprayer lapansi. The chizindikiro cha aerosol ndi limachokera ku muvi pansi. Pamene madzi ukufika mlingo ayenera kukhala kuti ndi mankhwala atsopano, popeza ntchito ya botolo alipo ndi Zimatheka ndi pang'ono linapendekeka, imene wakuyamwa chubu kumizidwa mu madzi.