"Isotretinoin": malangizo ntchito, zizindikiro, ndemanga

Chithandizo cha matenda osiyanasiyana a pakhungu ikuchitika kuyamika formulations munali mu zikuchokera isotretinoin ake. thunthu imatengedwa kuti dermatoprotektivnym zikomo katundu yake yapadera. The yokonza dzina chomwecho ntchito zochizira seborrhoea, ziphuphu. "Isotretinoin" malangizo ntchito akulimbikitsidwa kugwiritsa ntchito yekha atakambilana ndi dokotala. Malinga ndi ndemanga, wothandizila ndi ogwira njira yotupa pa khungu.

Kufotokozera za

Mankhwala "Isotretinoin" Ichitu retinoid. Yotsirizira amatanthauza ndilochokera vitamini A. akupita mankhwala yogwira - isotretinoin - kudziwika monga asidi retinoic ndipo ali maonekedwe a ufa chikasu. thunthu angathe neutralizing mofulumiracho. kugawa maselo a khansa. Mundawu poyamba ankagwiritsa ntchito mankhwala a khansa.

Patapita nthawi, ofufuza apeza wina achire katundu ufa mankhwala - izo akhoza kuchepetsa kupanga sebum ndi inhibiting kukula kwambiri za epithelium selo excretory ducts. Mundawu amalola panopa ntchito pofuna kuchiza ziphuphu zakumaso aakulu amatanthauza "Isotretinoin".

The formulations zochokera pophika izi yogwira akhoza kugwiritsidwa ntchito kunja ndipo pakamwa. njira mulingo woyenera amasankha dermatologist ndikatha kumfunsafunsa wodwala.

Kodi mankhwala?

Mankhwala "Isotretinoin" malangizo Buku akuonetsa kuti ntchito bwino kuchitira ziphuphu zakumaso mabala chikhalidwe ndi matenda ena apakhungu. Zotsatira achire mankhwala ali zimakhudzanso kamodzi pa zinthu zonse zimene zimachititsa kuti matenda amenewa. Choyamba, kuchepetsa kupanga sebum, pores amayeretsedwa.

Zokhudza zonse retinoid kumathandiza kukula kwa pathological tizilombo Propionibacterium acnes, zomwe zimabweretsa ziphuphu zakumaso, ziphuphu. Relief kutupa, normalization wa pH - monga mtengo wa lokonzekera. "Izoteretinoin" ntchito mwakhama pakhungu ndi cosmetology. Yogwira chigawo amalola kusonkhezera osati pa matenda, komanso kuthetsa zifukwa zimene zinachititsa kuti chitukuko cha ndondomeko yotupa.

Zikuonetsa ntchito

Onani kuti osavomerezeka ntchito "Isotretinoin" popanda mankhwala dokotala. Kukonzekera mtengo ntchito kunja pa maziko wa chinthu chomwecho yogwira zimasiyanasiyana mkati 280-650 rubles. Perekani mankhwala mawonekedwe piritsi pamaso pa pathologies ena. Ali:

• seborrhea;
• rosacea (kuphatikizapo chaukali);
• mitundu yonse ya ziphuphu zakumaso;
• nodulocystic ziphuphu zakumaso;
• zosiyanasiyana dermatitis;
• kobadwa nako ichthyosis.

Matenda ambiri izi ndi logwirizana chifukwa cha chiyambi - kwambiri sebaceous zopangitsa. Zimenezi, kumabweretsa kusokonezeka kwambiri bwino yachibadwa a khungu.

Kodi nanga njira?

Malinga ndi maphunziro ambiri, mphamvu ya mankhwala udakhazikika mwa zosiyanasiyana matenda khungu. "Isotretinoin," kwambiri amachepetsa ntchito zopangitsa sebaceous (90%) ndi normalizes njira kunachitika khungu. Madokotala kulengeza ntchito ngakhale mawonekedwe choopsa cha ziphuphu zakumaso mankhwala mu piritsi mawonekedwe "Roaccutane". Isotretinoin ntchito ngati mankhwala yaikulu yogwira.

Njira ntchito apakhungu bwino kuwonedwa mu mankhwala a ziphuphu zakumaso, rosacea, ndi dermatitis. retinoids angagwiritsidwe ntchito kwa ofatsa matenda zolimbitsa khungu. Akatswiri amanena kuti mankhwala m'njira imeneyi si owopsa kwa thupi kuposa makapisozi. Pamene m'kamwa isotretinoin ndende zake magazi kuchuluka kwa 2,000 ng / ml. Ngati tigwiritsa ntchito mafuta, mlingo sadzakhala upambana 60 ng / mL.

Kukonzekera zochokera isotretinoin

The yogwira pophika isotretinoin malangizo ntchito amatanthauza mwachibadwa zikuchitika retinoids. A ochepa mankhwala awa ali bwino chosakanikirana ndi thupi, ndi zotsatira zabwino pa khungu, kuchepetsa kupanga sebum, ndi kanthu antimicrobial. Ena kukonzekera kunja muli isotretinoin:

1. Retinoic mafuta.
2. "Izotreksin" (gel osakaniza).
3. "Retasol" (njira).

Pakuti makonzedwe m'kamwa mwa pathologies choopsa cha akatswiri khungu Kwalamulidwa mankhwala monga "Aknekutan", "Roaccutane", "kufufuta". Zikuchokera (isotretinoin ntchito monga pophika yogwira), ndi mlingo zingasiyane.

zotsatira zoyipazi

Pamene choposa mlingo isotretinoin amayambitsa zotsatira zina zoyipa. Chapatali iwo amaoneka zambiri chitetezo. Odwala amadandaula totupa, redness, ukuchoka khungu pa Yakanjedza ndi zidendene za mapazi, kuyabwa, misomaliyo dystrophy mbale. N'zothekanso zikamera wa cheilitis - matenda okhudza khungu pa milomo.

Mantha dongosolo ndi anthu ena odwala komanso akuvutika chifukwa mankhwalawa "Isotretinoin" mankhwala. Reviews amati angaoneke litsipa, kutopa kwambiri, mkhutu masomphenya acuity, osauka maganizo ndinso. Anthu ndi mphumu mu mbiri mankhwala ndi woopsa kwambiri. Zimenezi zingachititse kuti bronchospasm. Zotsatira zake zoyipa pa ziwalo masomphenya anaonetsa zizindikiro monga keratitis, blepharitis, chamawonedwe neuritis, conjunctivitis, diso mkwiyo.

Pa mbali pa mundawo m'mimba akufotokozera kapamba, kutsekula m'mimba, magazi mkati, kusanza, matumbo mucosal kutupa, matenda a chiwindi. Nyamakazi, kupweteka m'malo olumikizirana mafupa ndi minofu, hyperostosis - zizindikiro za mavuto isotretinoin pa dongosolo minofu ndi mafupa.

contraindications

Choyamba, mankhwala "Isotretinoin" malangizo Buku imaletsa ntchito pa mimba kapena mapulano. thunthu ndi embryotoxic ndi teratogenic zotsatira, tingayambe anomalies mu chitukuko ndi kubadwa zopindika mwana wosabadwayo. akatswiri amalangiza kuyamba kukonzekera mimba osati kale kuposa miyezi 3-4 pambuyo pa mapeto a mankhwala mankhwala. Panthawi imeneyi, milingo isotretinoin mu thupi kuti abwerere mwakale.

Iwo amaletsedwa kujambula retinoids iliyonse imene mkaka wa m'mawere, ngati hypersensitivity kapena tsankho, pamodzi ndi mankhwala mankhwala tetracycline. Dongosolo Oral mankhwala contraindicated milandu matenda aakulu a chiwindi ndi impso pa kuchuluka lipids ku seramu magazi ndi malignancies. Kwa odwala ndi hypervitaminosis A ndi siyabwino isotretinoin.

Mtengo wa mankhwala otsika mtengo kwambiri zochokera mankhwala - 280-350 rubles. Chithandizo kamwedwe, mlingo analogs amasankha yekha dokotala.

Kodi kutenga?

Isotretinoin ndi mu mawonekedwe a makapisozi kwa makonzedwe m'kamwa ayenera kumwa akamadya. Mlingo koyamba ndi amangoona zosakwana 0,1 mg wa pa kilogalamu ya kulemera kwa wodwalayo thupi. Kenako mlingo akhoza ziwonjezeke (mu nkhani ya mphamvu zabwino ndi kusowa mavuto).

Avereji tsiku mlingo (0.5 g) ndi kugawidwa mu magawo angapo. Malinga ndi kukula kwa matendawa kuti achuluke. Kumbukirani kuti tsiku akhoza kutenga magalamu zosaposa 10 isotretinoin. mankhwala kawirikawiri yaitali, masabata 16-24. The imeneyi pakati pa maphunziro a mankhwala ayenera kukhala miyezi iwiri.

Mankhwala "Roaccutane"

medicament Price mokwanira mkulu ndi dongosolo la 2700 rubles phukusi (20 mg wa mlingo). Wopanga ndi kampani Swiss mankhwala, "Hoffman-La Roche." Makapisozi "Roaccutane" zothandiza pa ziphuphu zakumaso zotukwana mu kwambiri, keratosis pilaris, ichthyosis, keratoderma.

Kutalika kwa mankhwala zimatengera mtundu wa matenda, ndi zambiri masabata 2-4. Tsiku akhale 0.5 mg wa yogwira pawiri pa makilogalamu 1 kulemera mtima. Mu yachibadwa kulolerana "Roaccutane" ayenera kuyamba gawo lachiwiri la mankhwala, amene kumatenga 20 milungu. Pankhaniyi, dokotala ayenera kuwunika ntchito yakuti pa matenda mphamvu. Ngati pali kuchepa kwa zotupa ndi 70-80%, mankhwala nthawi zimafika.

Features ya ntchito

Pa mankhwala "Roaccutane" zotheka aggravation matendawa. Pankhaniyi m'pofunika kuchepetsa kwa mlingo osachepera (0.5 mg / kg). Childs, mphamvu zabwino ndi yokhalitsa chifukwa chithandizo zingaoneke kudzera miyezi 1,5-2 atayamba chithandizo. Komabe, mu Zikavuta pamafunika wautali Inde wa phwando "Roaccutane" mankhwala.

Mtengo wa mankhwala pa maziko a isotretinoin zimadalira mlingo wa pophika yogwira. makapisozi akhoza muli 10 kapena 20 mg wa pawiri izi. Mutu mlingo ndi chithandizo regimens mankhwala sayenera kuyambitsa zotsatira zoyipa. Akatswiri alendo kunena kuti "Roaccutane" bwino analekerera ndi odwala.

The njira "Retasol"

Current zikuluzikulu za wothandizila ndi isotretinoin. Reviews odwala ndi dermatologists atsimikizire achire efficacy wa mankhwala. Yogwira mankhwala chiphunzitso lili 0,025 mg wa mu 1 ml. yankho A pambali odana ndi yotupa ndi limatha kudzichiritsa kanthu, ali ndi kulimbikitsa mpumulo wa khungu. lokonzekera cholinga cha ntchito khungu adakonzedwa. Pa tsiku la ndondomeko ayenera mobwerezabwereza kawiri. Nthawi chithandizo "Retasolom" amangoona 4-12 masabata.

Sikuti kutsatira njira osakaniza retinoids ena. Izi zingakubweretsereni chitukuko cha hypervitaminosis A. Zilibe mankhwala "Retasol" tetracyclines mankhwalawa kuchuluka intracranial kuthamanga chiopsezo.

Mu maonekedwe a njira mankhwala angagwiritsidwe ntchito pa matenda a ziphuphu zakumaso mu achinyamata ochokera zaka 11 zakubadwa. Njira zapita mayesero matenda, imene chitetezo ake zatsimikiziridwa. "Retasol" ndi abwino kwa khungu wochuluka.

umboni

odwala ambiri akhala bwino ntchito zochizira mankhwala zochokera mankhwala yogwira monga isotretinoin. Analogues mankhwala ayenera kusankha katswiri.

Mu miyezi ingapo ya mankhwala mwamphamvu zachilengedwe retinoid amalola kuti tichotse ziphuphu zakumaso, ziphuphu rosacea. More aakulu matenda khungu zofuna maphunziro mobwerezabwereza mankhwala. Only mu nthawi zina, mavuto zidzachitika, nthawi zambiri anamuona chitetezo cha m'thupi: matupi awo sagwirizana totupa, dermis youma redness. Izo kutiletsa kutenga mankhwala zochokera isotretinoin pa mapulani mimba, atanyamula mwana kapena mkaka wa m'mawere.