Epidermal necrolysis poizoni: zizindikiro zimayambitsa, chithunzi

Chipangizo matenda dermatological kuti akhoza kukhala moyo pachiswe, sanalembedwepo zambiri. Komabe, iwo ali. Imodzi mwa zimenezi akuti oopsa epidermal necrolysis. kudwala Izi ndi matenda osowa wa khungu zimene zingachititse kuti imfa.

kudwala ndi chiyani?

Otani epidermal necrolysis - aakulu awo sagwirizana kudwala, zomwe zimachititsa detachment a wosanjikiza kumtunda kwa khungu. Iye ndiye wamwalira ndi thupi wadwala kuledzera amphamvu. Popanda mankhwala oyenerera anthu kumachitika sepsis ndi imfa.

Bullous imfa kusinthika ndi adzatengedwe nkhati osati khungu, komanso zimagwira ntchito zosiyanasiyana mucous. Matendawa sioneka kwambiri. Mfundo yakuti kunyanyala zina mkati mucous zimagwira ntchito zosiyanasiyana, omwe nthawi zambiri kumayambitsa magazi chapamimba, kulephera kupuma, ntchito ndi kuyan'anila ena a chamoyo.

Nthawi zambiri akufotokozera poizoni epidermal necrolysis pambuyo kugwiritsa ntchito mankhwala ena. Komabe, zifukwa mwina ena. Zikamera ndi zochita matenda kuli kovuta kulosera.

zimayambitsa

Chifukwa ambiri a matenda ndi ntchito mitundu ina ya mankhwala:

• Sulfonamides.
• Macrolides 'mankhwalawa. "
• Penicillin mankhwala.
• Anticonvulsant: "lamotrigine", "carbamazepine", "Phenobarbital".
• Quinolones "Trovafloxacin".
• Protivovspalitelnye mankhwala nonsteroidal: "Indomethacin" "Ibuprofen," "piroxicam".

The zochitika ndi otsika kwambiri ndipo okha 1 mlandu pa anthu 1 miliyoni pa chaka. Nthawi zambiri zimakhudza akazi. Age ndi zofunika, monga ambiri a milandu kudwala zimawonedwa patapita zaka 55.

Kuwonjezera kumwa mankhwala a kuyambitsa zikamera necrolysis akhoza kukhala ndi kachilombo ndi matenda staph.

Features wa chitukuko cha matenda

Epidermal necrolysis poizoni ikusintha mofulumira zokwanira. Mu nkhani ya matenda chitetezo cha m'thupi sangathe bwino kuzindikira ndi n'chongoletsa thunthu poizoni mu nkhani iyi mankhwala kuchipatala. Sayanjana ndi wamphamvu kwambiri.

Pankhaniyi, chitetezo cha m'thupi akuukira khungu, chifukwa amaona iwo thupi lina. Choncho lamulo la kuwola mapulotini ndi akusokoneza. Khungu wayamba kudziunjikira poizoni chopatsa okwana kuledzera. Ngati nthawi sayamba chithandizo, munthuyo adzafa.

Species ndi kutanthauzira

Otani epidermal necrolysis (matenda, Takambirana kale) akhoza wachinsinsi motere:

1. Idiopathic. Zimachitika paokha, ndipo chifukwa chake sindingathe adzakhazikika.
2. Chifukwa cha mankhwala osokoneza bongo ena.
3. Akuwuka mchikakamizo cha matenda staph. Mtundu wa kudwala amawapeza makamaka ana. Pankhaniyi, n'zotheka imfa Kwaletsedwa.
4. Pamodzi ndi matenda ena.

zotupa akhoza wapezeka pa malo limeneli la matako, mapewa, chifuwa, mimba ndi kumbuyo, m'kamwa mucosa.

symptomatology matendawa

epidermal poizoni necrolysis (syndrome Lyell a) ndi ambiri yodziwika ndi zizindikiro zotsatirazi:

• Total thupi kuphwanya chikhalidwe chimene kumaonekera kufa kudya, mutu wowonjezera kutentha woyambira. Nthawi zambiri chizindikiro cha kudwala kwambiri chifukwa ludzu.
• Ululu ndi kusapeza mu nembanemba wa mucous. Komabe, tilinazo yawo kwambiri kuchuluka. Mwachitsanzo, pamene mukudya wodwala akumva kupweteka pamene Pomeza.
• Nthawi mawanga ofiira, totupa ndi zotupa pa khungu ndi nembanemba mucous. Nthawi zambiri zimakhudza pafupifupi 30% ya thupi, ngakhale akhale yokulirapo.
• Exfoliation a khungu. Pankhaniyi, khungu amayamba kuotcha ngakhale pansi kukhudza ofooka. Ngati zinkakhala m'dera la khungu kuchotsa bala magazi adzaoneka pansi.
• Aimpso insufficiency.
• Opatsirana ndondomeko. chakuti khungu akhoza silingayende bwino ndi kuteteza anthu kukhudzana ndi tizilombo toyambitsa matenda. zinthu angachotsedwe sepsis.
• Mu masiteji ina ya matenda penyani madzi m'thupi, tachycardia ndi hypotension.
• Kupweteka minofu.
• Malungo ndi chifuwa.
• Anorexia.
• Kunyansidwa ndi kusanza.

Kumbukirani kuti chifukwa zotupa mucosal zimachitika mofulumira kuposa matenda khungu. Ndiye kenako wamuona bwino ngati magawo koyamba poizoni epidermal necrolysis, chithunzi cha amene si kukomoka mtima, pang'ono noticeable.

diagnostics Features

Ngati muli ndi kukayikirana wa poizoni epidermal necrolysis, muyenera kufunsa dokotala nthawi yomweyo. Iye ayenera kupanga masiyanidwe matenda ndi mokwanira kwambiri, womwenso:

1. Kukondetsa wovulalayo madandaulo. Akunena kuti aliyense zotupa ululu zomverera.
2. Kusonkhanitsa mbiri mtima. Kuti, dokotala ayenera tikupeza kuti iye chifuwa aliyense amene amathandiza kuti chitukuko cha zimenezi zingachitike zovuta. Iwo m'pofunika kudziwa mavuto ofanana mu achibale a munthu wodwalayo.
3. Kunja mosamala mtima. Pankhaniyi, ndi dermatologist limatisonyeza khungu, pamaso pa zotupa ndi matuza pa Kakhungu mucous. Wodwala akhoza kuchita kwa chilengedwe chawo si zokwanira ndithu.
4. Analysis magazi okwana. Iye mpata kudziwa milingo ngati zapamwamba za maselo oyera, pali maselo mwana magazi, mathamangitsidwe wa erythrocyte sedimentation. Ngati magawo awa kupitirira malire wabwinobwino, zinthu limasonyeza pamaso kutupa.
5. Amuzolengedwa kusanthula magazi. Ngati chifukwa pali msinkhu apamwamba bilirubin ndi chochepa kapena kuchuluka kwa mapuloteni, wodwalayo mwina mavuto ndi ntchito impso.
6. Urinalysis. kafukufuku n'chofunikanso kudziwa impso ntchito. Ngati pali magazi, ndiye, ndi nkhawa lonse mu mkodzo.
7. Kuyeza ntchito za mtima, magawo magazi.

Matendawa ndi kofunika kusiyanitsa poizoni epidermal necrolysis zina matenda: pemphigus, fever, erythema, bullous impetigo, ndere planus.

Features mankhwala

Umaimiridwa ndi matenda ayenera ankachitira. Apo ayi, wodwala akhoza kudikira sepsis ndi imfa. Ngati wodwala alipo zizindikiro pamwamba, ndiye ayenera kuperekedwa msanga zinthu kuchipatala. Ngati matenda ovuta, wozunzidwayo anaikidwa mu odwala kwambiri komwe madokotala angapereke iye ndi chithandizo chokwanira.

The Komiti, amene amadwala, ayenera kukhala wosabala, amene adzachotsa kuthekera kujowina matenda ena. Kudwala Chithandizo kumafuna kuchotsa zinthu zimene zinayambitsa matenda.

Koma mankhwala, ndiye adzabwera kuthandiza corticosteroids ndi mankhwala. Komanso, ayenera mwadongosolo mankhwala kulowetsedwa. Maantibayotiki angathe kugwiritsidwa ntchito mu chochitika kuti wodwalayo ali inalowa matenda sekondale.

Otani epidermal necrolysis (icho chiri, mukudziwa kale) Tifunikanso ankachitira ndi thandizo la chuma m'dera kuthandiza kubwezeretsa khungu labwino kubadwanso dzanzi (othetsa ululu), mafuta, antiseptics.

Komanso, muyenera kutsatira mfundo za mankhwala:

1. Ziyenera kukhala zotheka mwamsanga bwino m'thupi mankhwala atengedwa kale. Limagwiritsa ntchito enemas.
2. Ndi zofunika kutenga mankhwala zimathandiza kuti kubwezeretsa yachibadwa kagayidwe madzi amchere, monga "Regidron".
3. Doctor mankhwala mankhwala chitetezo chiwindi, makamaka "Gepabene".
4. Kulandira nthumwi kuti kuchepetsa magazi clotting.

Kodi mavuto angayambe?

Ngati inu amapezeka ndi poizoni epidermal necrolysis, zosokonezeka ingakhale monga iyi:

• Chitukuko cha matenda aakulu bakiteriya.
• Aakulu madzi m'thupi, zomwe zingayambitse imfa wodwalayo.
• Kumwalira kwa kwambiri kuchuluka kwa khungu. Ngati munthu wotaya oposa theka a khungu, izo akuyembekezera imfa.
• Kuyanika wa khungu, maonekedwe a zipsera pa iye, kusintha mtundu.
• Matenda kukokoloka kwa nembanemba wa mucous.

kaonedwe

Ngati mankhwala a kudwala sanali anayamba Patapita nthawi, amafa angafikire 70%. Imfa ya mbali yofunika kwambiri khungu azitentha mtima atengeke kwambiri matenda.

Panthawi yake anayambitsa mankhwala osati kuthandiza muchisiye matenda, koma Kutithandizanso mwayi kupewa mavuto zoipazi monga magazi mkati, kuwononga dongosolo genitourinary, kulephera kutenga chakudya, kulephera impso ndi chiwindi.

Tikumbukenso kuti ana akufa matenda ndi zochepa kwambiri kusiyana ndi achikulire. Ngati wodwala watsala ndi kanthawi kochepa 60 chaka wosaiwalika, izo zanyengo zokhumudwitsa. Komabe, mankhwalawa akhoza kusintha chikhalidwe chake.

kudwala Kuteteza

dzina lina kudwala ichi monga poizoni epidermal necrolysis - syndrome Lyell a. Photos of matenda ndi bwino kuyang'ana anthu n'zaka. Izi ndi kudwala zovuta, zomwe zikhoza kupewedwa ngati inu kutsatira njira zodzitetezera:

• Mankhwala ayenera kumwedwa ngati ali zotchulidwa dokotala.
• The katswiri ayenera kudziwa ngati muli ndi zochita aliyense matupi awo sagwirizana.
• Kaya kudwala mukakhale, sayenera kumwa kuposa 7 mankhwala imodzi.
• Kodi musalankhule staphylococcal ndi matenda yotupa khungu.
• Musayandikire irritant aliyense zomwe zingachititse chifuwa.

Monga mankhwala, ndiye izo zidalira pa makhalidwe a chamoyo ndi chilakolako wodwalayo kuthana ndi kuphwanya lapansi. Khalani wathanzi!