"Dexylant": malangizo, zizindikiro, zofanana, ndemanga

Kodi mankhwala monga Dexylant ndi chiyani? Malangizo, mafananidwe ndi zidziwitso za mankhwalawa zidzawonekeratu. Komanso, mudzaphunziranso za matenda omwe mankhwalawa akulamulidwa ndi zomwe odwala akunena za izo.

Mfundo zazikulu zokhudza matendawa

Ndi matenda ati omwe amachitira mankhwala Dexilant? Malinga ndi malangizo, mankhwala omwe ali mu funsowa amasonyeza kuti mankhwalawa ndi othandiza kwambiri mu matendawa, omwe ndi matenda a reflux a gastroesophageal. Imeneyi ndi matenda omwe amapezeka kwambiri m'thupi ndipo amachokera ku reflux, ndiko kuti, kuponyedwa mobwerezabwereza kwa zinthu za duodenum kapena m'mimba. Chifukwa cha matendawa, chiwindi cham'mimba ndi, nthawi zina, ziwalo zapamwamba, kuphatikizapo pharynx, larynx, bronchi ndi trachea, zimaonongeka.

Zizindikiro zazikulu za matendawa

Kodi GERD imawonetseredwa bwanji? Zizindikiro (chithandizo cha matendawa chiyenera kuika kokha munthu wodziwa bwino gastroenterologist), zoterezi nthawi zonse zimakhala zofanana. Nthawi zambiri wodwala amadandaula chifukwa cha kupweteka kwa mpweya, kumenyedwa ndi mpweya kapena asidi, kupweteka kwambiri pammero, kupweteka m'mimba kumene kumachitika mutatha kudya, komanso kusokonezeka m'mimba, zomwe zimawonjezeka mutatha kudya.

Kodi mungathenso bwanji kudziwa GERD ndi matenda opatsirana? Kuchiza kwa matendawa kumayambira pakutha kwa bile ndi mchere wambiri wa chakudya. Tiyeneranso kukumbukira kuti nthawi zina odwala omwe ali ndi matendawa amakhala ndi zizindikiro monga kusanza ndikulimbikitsanso, kumverera kwachisokonezo kumbuyo kwa sternum, mankhwala osokoneza bongo komanso dysphagia. Kuwonjezera apo, anthu omwe ali ndi matenda opatsirana amatha kudandaula chifukwa cha kupweteka pachifuwa, zomwe amapereka kumapewa, mkono, khosi ndi kumbuyo.

Ngati muli ndi chizindikiro chimodzi mwazizindikiro, muyenera kupita ku polyclinic kuti mukawone bwinobwino.

Kupanga mankhwala, ndondomeko yake ndi mawonekedwe ake

Ndi mankhwala ati omwe amathandiza kwambiri ku GERD (zizindikiro, kuchiza matendawa zikufotokozedwa m'nkhani ino)? Kawirikawiri, chifukwa cha mankhwala a matendawa, komanso kuthetsedwa kwathunthu kwa zizindikiro zake zachipatala, akatswiri amalimbikitsa kutenga mankhwala a Dexilant. Amapezeka ngati mawonekedwe omasulidwa omasulidwe, komanso ndi thupi lofiira lomwe lili ndi chivundikiro cha buluu pomwe TAP imagwiritsidwa ntchito.

Zomwe zili m'kati mwa capsules ndizoyera kapena zoyera. Chigawo chawo chogwira ntchito ndi dexlansoprazole. Kuphatikizapo mankhwalawa ndi othandizira kwambiri monga giprolose, grits, shuga, macrogol 8000, magnesium carbonate, polysorbate 80, sucrose, silicon colloidal dioxide, giprolose, substituted giprolose, triethyl citrate, hypromellose, methyl methacrylate-methacrylic acid copolymer, talc, methacrylic acid dispersion, titanium Dioxide.

Mukhoza kugula makapisozi Amadzimadzi m'mabotolo a polyethylene omwe amaikidwa mu mapaketi a makatoni.

Zochitika za mankhwala a mankhwala (capsules)

Kodi mankhwala opatsirana mankhwala monga Dexilant ndi otani? Ndemanga imanena kuti mankhwalawa ndi proton pump inhibitor (IPN). Zimatha kuthetsa kusungunuka kwa madzi a chimbudzi chachikulu mwa kuletsa K + / H + -ATPase yomwe ili m'maselo osokoneza m'mimba. Komanso atatha kumwa mankhwalawa, gawo lomalizira lachinsinsi la hydrochloric acid limatsekedwa.

Kodi Dexylant amagwira ntchito bwanji? Malangizo akuti atatha kutenga kapsule mkati mwake, amagawanika m'mimba ndipo amatulutsa mitundu iwiri ya granules yomwe ili ndi zokutira. Motero, chinthu chachikulu cha wothandizirayi chimayamba kugwira ntchito mwakhama malingana ndi pH mlingo m'madera osiyanasiyana a m'matumbo aang'ono.

Chifukwa cha kapangidwe ka kapule ndi granular zokhazikika, kukonzekera kwa "Dexilant", zomwe zimaperekedwa pansipa, zimakhala ndi nthawi yaitali, komanso zimapangitsa kuchepa kwakukulu kwa chitetezo cha madzi chapamimba kwa nthawi yaitali.

Zisonyezo za kutenga makapisozi a mankhwala

Kodi ndizifukwa ziti zomwe wodwalayo adayitanitsa mankhwala monga Dexilant (mtengo wamagulu a mankhwala ndi apamwamba kwambiri)? Malinga ndi malangizo omwe chida ichi chikuwonetsedwa ku phwando:

• Ndi odwala opaleshoni oopsa kwambiri (mankhwala);
• Kusokonezeka kwa matenda oopsa komanso kupuma kwabwino (monga chithandizo chokonza chithandizo);
• Matenda a reflux, kuphatikizapo matenda osagwirizana ndi reflux (monga mankhwala opatsirana).

Zotsutsa pa kayendetsedwe ka oral capsules

Kodi ndi zinthu ziti zomwe simungagwiritse ntchito mankhwala a Dexilant? Malangizowo amadziwitsa zotsatizana zotsatirazi kulandira mankhwalawa:

• Zaka zapakati;
• Kumvetsetsa kwambiri kwa zigawo zonse za mankhwala;
• Kugwiritsira ntchito mofanana ndi HIV protease inhibitors;
• Nthawi yamimba;
• Nthawi yoyamwitsa.

Mmodzi sangathe kunena kuti mankhwala omwe ali nawowa ali ndi sucrose. Pankhani imeneyi, ntchito yake sivomerezedwa kwa anthu omwe ali ndi matenda a glucose-galactose (obadwa) fructose, komanso kusowa kwa shuga-isomaltase.

Mankhwala osamalitsa a mankhwala

Mosamala, mankhwala "Dexylant" (mafananidwe a mankhwala omwe ali kumapeto kwa nkhaniyi) amaperekedwa ku phwando lofanana:

• "Tacrolimus."
• Zizindikiro za isojekyme CYP2C19.
• Warfarin.
• "Methotrexate."

Mankhwala "Osautsa": malangizo othandizira

Tengani mankhwalawa ndizofunidwa pokhapokha mutagwirizanitsa ndi gastroenterologist wodziwa bwino. Ma capsules amathandizidwa pamlomo palimodzi, mosasamala nthawi ya chakudya.

Ngati ndi kotheka, chipolopolo cha capsule chikhoza kutsegulidwa. Pankhaniyi, zomwe zili mkatizi ziyenera kutsanulidwa mu supuni, zosakaniza ndi msuzi wosapanga, ndipo nthawi yomweyo imame popanda kutafuna.

Kodi mungatani kuti muzitha kudwala matenda osokoneza bongo? Ndili ndi matendawa, Dexylant (60 mg) imayikidwa kamodzi pa tsiku. Njira yopangira mankhwala ndi mankhwalayi ndi masabata eyiti.

Mankhwala othandizira atatha kuchiza matenda oopsa, komanso kuchepetsa kupweteka kwa mtima, amafunika kutenga 30 mg mankhwala nthawi imodzi. Pachifukwa ichi, njira ya chithandizo iyenera kukhala pafupi miyezi isanu ndi umodzi.

Pamaso pa odwala opaleshoni oopsa kwambiri ndi ochepetsetsa, mlingo woyenera wa mankhwalawo ndi 60 mg patsiku. Njira yothandizira matenda oterowo ayenera kukhala miyezi isanu ndi umodzi.

Kodi chithandizo cha chizindikiro cha GERD kapena NERD chiri bwanji? Mankhwalawa "Deksilant" (30 mg) ndi matendawa amasankha kapu imodzi kamodzi pa tsiku. Njira yothandizira matendawa iyenera kukhala patatha milungu inayi.

Kwa anthu omwe ali ndi vuto la chiwindi chogwira ntchito mopitirira malire kwambiri, mlingo wa tsiku ndi tsiku wa wothandizirayo suyenera kupitirira 30 mg. Palibenso dokotala wokhudzana ndi kumwa mankhwalawa ndi anthu omwe ali ndi vuto lalikulu.

Kukonzekera kwa mayendedwe okalamba kwa okalamba, komanso anthu omwe ali ndi vuto la chibwibwi komanso chiwindi chowopsya sichifunika.

Mawonedwe olakwika atatha kumwa mankhwala (capsules)

Kodi zotsatira zowopsa zingayambitse chiyani? Ndemanga imanena kuti atalandira mankhwalawo, funsoli limakhalapo mwa odwala. Zina mwa izi mungathe kuziganizira izi:

• Kutsekula m'mimba, matenda opatsirana pogwiritsa ntchito mankhwala osokoneza bongo, kutupa kwa ana, kupweteka m'mimba, kudzimbidwa, kunyowa;
• Epidermal necrolysis, kusanza, exfoliative dermatitis poizoni, matenda opuma kupuma (kumtunda), hypersensitivity;
• Matenda a hyponatremia, machitidwe a anaphylactic, kuyabwa, matenda oopsa a erythema exudative (matenda a Stevens-Johnson), hypomagnesemia, candidiasis a m'kamwa;
• Kuchepetsa kunyowa kwambiri, kupweteka ndi kupweteka m'mimba, ming†™ oma, pakamwa pouma, kuthamanga, kutupa kwa m'kamwa mucosa, leukocytoclastic vasculitis, kuperepesa;
• Kusintha chiwindi, kugwira ntchito, kuthamanga kwa thupi, kutaya magazi, kupweteka, chifuwa;
• Kuthamanga kwamoto, laryngeal edema, kuwonjezeka kwa magazi, kumverera kolimba mmero, mutu, idiopathic thrombocytopenic purpura;
• Umaliseche, kuwonongeka kooneka, dysgeusia, paresthesia, kumva, kumva;
• Sitiroko, vertigo, kusokonezeka kwa ischemic, kuonongeka koyang'ana, kulingalira mozama, kukhumudwa kwa nkhope, kusowa tulo, kusintha kwa njala, kuvutika maganizo, zofooka ndi zina zotero.

Zizindikiro za overdose

Kodi zotsatira zake zimakhala zotani pamene mlingo wa mankhwala ovomerezeka ovomerezedwa ndi dokotala wapitirira? Pakadali pano, palibe malipoti okhudzidwa kwambiri okhudzidwa chifukwa cha kugwiritsa ntchito mankhwalawa. Pa nthawi yomweyi, akatswiri amanena kuti pogwiritsa ntchito mankhwalawa pa mlingo wa 120 kapena 300 mg, palibe zotsatira zoyipa zomwe zimachitika. Ponena za kumwa mankhwalawa 60 mg kawiri pa tsiku, njirayi imayambitsa kuwonjezeka kwa magazi kwa 140/90 mm Hg. Art.

Kodi kuchotsa zizindikiro zowonjezereka? Pamaso pa mawonetseredwe a chipatala, mankhwala opatsirana amachitidwa. Tiyeneranso kukumbukira kuti dexlansoprazole sichidodometsedwa ndi hemodialysis.

Kuyanjana kwa Mankhwala

Kodi dexlansoprazole imagwirizana bwanji ndi mankhwala ena? Malinga ndi malangizo, chogwiritsira ntchitochi chingaperekedwe kwa odwala omwe amatenga Clopidogrel, popanda chiopsezo chogwirizana. Pankhani ya phwando lofanana la njira zowonetsedwa, kukonzekera kwa regimen ya dosing sikofunikira.

Panaliponso kupezeka kwathunthu kwa mgwirizano wofunikira wa mankhwalawa mu funso ndi "Diazepam", "Theophylline" ndi "Phenytoin".

Kugwiritsidwa ntchito kofanana kwa dexlansoprazole kungakhudzitse kuyamwa kwa mankhwala omwe bioavaability imadalira pH mlingo m'mimba (mwachitsanzo, salt salts, ampicillin esters, digoxin, ketoconazole ndi Erlotinib).

Kupeza "Dexylant" palimodzi pokhapokha ndi "Tacrolimus" kumathandiza kuonjezera mchere wa m'magazi, makamaka kwa anthu pambuyo pa kusindikizidwa.

Ndi kugwiritsa ntchito mofanana kwa mankhwala omwe ali mu funsoli ndi "fluvoxamine" pali mwayi wapamwamba woonjezera zotsatira za systemic za kale.

Kugwiritsira ntchito methotrexate ndi dexlansoprazole panthaŵi yomweyo kungachititse kuti chiwonjezereke, komanso kusungidwa kwa msinkhu waukulu kapena woyamba wa metabolite m'magazi a magazi. Ngati mukufuna kutenga mlingo wa methotrexate, ndiye kuti mukulimbikitsidwa kuti muthetse pang'ono kuchotsa dexlansoprazole.

Nthawi yogwirizanitsa ndi nthawi ya kugonana

Kodi n'zotheka kutenga Dexilant panthawi yogonana? Malinga ndi malipoti a akatswiri, panthawi ya mimba mankhwalawa akutsutsana.

Ngati mankhwalawa ndi ofunika kuti asankhe mayi woyamwitsa, ayenera kusiya kuyamwitsa.

Mfundo Zapadera

Kodi ndi chitsimikizo chiti chimene wodwalayo angapereke asanafotokoze mankhwala a Dexylant?

Musanayambe kulandira chithandizo ndi dexlansoprazole, m'pofunika kuchotsa kupezeka kwa matenda osokoneza bongo kwa wodwalayo, chifukwa kumwa mankhwalawo kungasokoneze zizindikiro, komanso kuchepetsa kuika kwa matenda oyenera.

Ngati zizindikiro zonse za matenda alipo zikupitirirabe, ngakhale kuti ndizokwanira, ndiye kuti padzafunikanso kufufuza.

Pogwiritsira ntchito proton pump inhibitors, omwe kwenikweni, dexlansoprazole ndi ofanana ndi, amachititsa chiwopsezo cha mawere m'mimba limodzi ndi kutsekula m'mimba, omwe amagwiritsa ntchito mabakiteriya osiyanasiyana, kuphatikizapo mtundu wa Clostridium difficile. Matenda oterewa nthawi zambiri amapezeka kuchipatala. Mfundo imeneyi iyenera kuganiziridwa, ngati chikhalidwe cha munthu sichikuyenda bwino ndi chithandizo cha kutsekula m'mimba. Pankhani iyi, odwala amalimbikitsidwa kugwiritsa ntchito dexlansoprazole yachangu kwa mankhwala ochepa.

Kwa anthu omwe amalandira mankhwala osokoneza bongo, kapena mankhwala owonjezera ndi proton pump inhibitors kwa miyezi khumi ndi iwiri kapena kuposerapo, chiopsezo cha mafupa a mafupa a manja, mafupa a mafupa ndi mzere wa msana akuwonjezeka kwambiri. Choncho, odwala omwe ali ndi chiopsezo cha osteoporotic fractures ayenera kutsatira nthawi zonse.

Nthawi zina kumbuyo kwa kumwa mankhwala mu funso, hypomagnesemia zozizwitsa komanso zozizwitsa zinawonedwa mwa odwala. Monga lamulo, zinthu zoterezi zinayamba ngati mankhwala "Deksilantom" adatenga miyezi itatu. Tiyenera kukumbukira kuti zizindikiro za hypomagnesemia ndi arrhythmia, tetany ndi convulsions. Thandizo la matendawa likufuna kuti m'malo mwa magnesium alowe ndikuchotsedwe kwa proton pump inhibitors.

Kwa anthu omwe amafunikira chithandizo cham'tsogolo nthawi zonse kapena mofanana ndi kutenga IPN ndi digoxin kapena mankhwala ena omwe angayambitse hypomagnesemia (kuphatikizapo diuretics), magnesium m'magazi ayenera kuyang'aniridwa nthawi zonse (nthawi zonse komanso nthawi).

Poona kuti akhoza kukhala ndi chizungulire, komanso kupweteka kwa maso pa nthawi ya chithandizo, Dexilant ayenera kupewa kuyendetsa magalimoto ndi njira zina zomwe zimafuna chidwi chenicheni kuchokera kwa munthu.

Mankhwalawa "Dexylant": ofanana, mtengo, ndemanga

Kodi chingalowetse mankhwala otani mu funso? Akatswiri amanena kuti zizindikiro zazikulu za mankhwalawa ndi izi:

• "Veloz" - chida chothandizira kuthana ndi kuchepa kwa acidity. Zomwe zimagwira ntchito mofulumira zimalepheretsa kupanga mankhwala owonjezera, kuyambitsa ndi kuthetsa ululu.
• "Barol" - m'makhalidwe ake ali ofanana ndi "Wopanda".
• "Geerdin" - imabwezera mwamsanga uchidulo, imalepheretsa kuwonongeka kwa makoma a matumbo, komanso imachotsa kupweteka kwa mtima.

Komanso mafananidwe a mankhwala otchulidwawo ndi kukonzekera "Omez". Ndi chiyani chabwino - "Omez" kapena "Dexilant"? Yerekezerani ndalamazi sizingatheke, chifukwa zili ndi zinthu zosiyana, ngakhale kuti zonsezi zimatchedwa kuchepetsa kuwonjezeka kwa acidity wa mimba yamimba.

Nthawi zina, akatswiri amalimbikitsa kugwiritsa ntchito mankhwalawa "Nexium" pofuna kuthandizira matenda a reflux a gastroesophageal. Pachifukwa ichi, odwala ali ndi chidwi chosankha - "Nexium" kapena "Dexylant"? Madokotala amati awiri omwe tatchulidwa pamwambawa akulimbana ndi ntchito yawo. Komabe, posankha mankhwala enaake, ziyenera kuganiziridwa kuti mankhwala oyamba amachititsa zotsatira zochepa.

Kodi capsules ndi otani? Mtengo wa mankhwala awa umadalira kuwonongeka kwa intaneti. Pafupifupi mtengo wa malowa ndi pafupifupi ma ruble 900.

Zimene anthu amanena zokhudza odwala medicament? anthu ambiri amene mankhwala izi ponena kuti ali overpriced. Komabe, akatswiri amanena kuti mankhwala othandiza kwambiri. Iye ali ndi kanthu yaitali ndipo mwamsanga matenda a acidity wa madzi muzituluka. Choncho madokotala n'chakuti kuti "Deksilant" angayambitse zotsatira zina mbali, koma nthawi zambiri kutha pamene kusintha mlingo wake tsiku.

Tiyeneranso kuti kudziletsa utsogoleli wa mankhwala oletsedwa. Chimenechi ndi chifukwa chakuti mu udindo wake ayenera kumwedwa kuganizira ngati wodwalayo matenda a impso ndi chiwindi, komanso zaka wodwalayo.