Creatinine chilolezo

Mankhwala ano, mawu akuti "chilolezo" omwe akuimira kachulukidwe chizindikiro liwiro mayeretsedwe madzi ena kwachilengedwenso. Kugwiritsa ntchito chizindikiro uyu kwambiri tikulitse kumvetsa kwathu kwa pharmacokinetics ndi pharmacodynamics awa ndi zinthu zina.

Choncho, mwachitsanzo, creatinine chilolezo anatsimikiza ntchito mayesero matenda Reberga-Toreeva. Dziwani kuti mu nkhani iyi n'zotheka kudziwa mlingo kusefera ngati chikhazikitso endogenously apanga zofunikira kuchokera kunja (kwa mankhwala ndi njira zina). Kuyesa imagwiridwa ndi kuwerengetsa mphamvu zosefera (glomeruli) wa madzi mlingo kumasulidwa ku chinthu makamaka. Nkhaniyi umachitika mu nthawi yoikika (makamaka - tsiku).

Ponena za creatinine, ayenera kulabadira chakuti kuchotsa izo mthupi ndi makamaka chifukwa ntchito kusefera a impso. Kuchokera pa ichi, monga kugunda chilolezo creatinine chidzakhala chapadera mu kufufuza aimpso uziyenda glomerular kusefera. Tikumbukenso kuti chithunzi ichi amakhala osati mphamvu zinchito za dongosolo fyuluta, komanso ena kusokoneza ena a ziwalo ndi kachitidwe. Kusinthidwa kunsi, creatinine chilolezo ndipo mwina zimasonyeza kuchepa magazi impso (atherosclerosis, ndi lakuthwa pachimake ndi chitukuko - thromboembolism).

Mlingo wa sakuyendetsa ntchito aimpso zikadzatha zaka makumi anayi. Kuchepetsa mlingo kusefera glomerular wa 1% pachaka. Patatha zaka makumi asanu ndi limodzi, mlingo wa ntchito yafupika pang'ono msanga (kusintha kwenikweni chikugwirizana ndi kukalamba lake). Komabe, tisaiwale kuti mawonetseredwe aliyense zimenezo kusandulika mwaonapo chifukwa okalamba ndi liwiro njira zonse kagayidwe kachakudya, kuphatikizapo kaphatikizidwe wa amkati creatinine.

Pokonzekera chitsanzo Rehberg m'pofunika kuchotsa kugwiritsa ntchito mankhwala ena zimene zingakhudze zochita za kafukufuku (mankhwala "tochepa" "Furosemide", "Corticotropin", "Methylprednisolone," "Thyroxine" ndi ena).

Kuika nyemba mkodzo zitsanzo zosankhidwazi imagwiridwa, komanso kuyesa kwa magazi pa mlingo avareji plasma creatinine.

Mwa zizindikiro cholinga phunziro: endocrine kudwala, ziyenera a ntchito aimpso zinchito, komanso adziwe amene amadza chifukwa cha zolimbitsa thupi.

Malinga ndi mlingo wa kuchepetsa chilolezo chimatanthauza kuyan'anila awa kapena ena.

• 30 ml ya / mphindi / m2 ndi 1.7 - kuchepa ntchito aimpso mu zolimbitsa;
• 30-15 ml ya / mphindi / m2 1.7 - pamaso pa kulephera aimpso (kapena kulipidwa digiri subcompensated);
• <15 ml / mphindi / m2 1.7 - aimpso kulephera decompensation gawo.

Nkofunika kudziwa kuti mphamvu zinchito za dongosolo kusefera Mzimuyo chilolezo aimpso wa creatinine, mlingo umene pa chitsanzo Reberga limasonyeza impso yachibadwa.

Komabe, ena matenda sikumachititsa kuti kusintha chizindikiro (mwachitsanzo, aakulu pyelonephritis).

creatinine mlingo mu magazi zimadalira ntchito kaphatikizidwe ake amkati ndi pa mlingo wake wa excretion wa mkodzo. Nkofunika kuzindikira kuti chithunzi ichi kumadalira osati kokha pa ntchito dongosolo sefa, komanso liwiro ndi buku la reabsorption zinthu mu mapangidwe mkodzo chachikulu.

Choncho, panopa Reberga nyemba (kudziŵa creatinine chilolezo) zokwanira kupeza ntchito ambiri mankhwala matenda. A kugwirizana pakati pa chilolezo ndi impso ntchito amapereka mkulu matenda tanthauzo ndondomeko.