"Suxamethonium mankhwala enaake": kufotokoza zinthu, mbali-zotsatira ndi ndemanga

Zochita mankhwala angapo mankhwala chofunika Mwachitsanzo, kubweretsa thupi wodwala mu boma chofunika ntchito opaleshoni. Kayendetsedwe zimafunika chongopeka chikwiyire zosangalatsa mtheradi minofu. Chifukwa chaichi, ntchito zambiri mankhwala "suxamethonium mankhwala enaake" (malonda dzina la mankhwala - "Listeon"). mankhwala makamaka ntchito mabungwe apadera zachipatala. ndicho kanthu ake pharmacological chiyani? N'koopsa ntchito ndalamazo? Kodi muyenera kukhala okonzeka ndi kugwiritsa ntchito mankhwala "suxamethonium mankhwala enaake"? Kufotokozera za kukonzekera ndi zina mwa ntchito zake nkhani zotsatirazi m'nkhani ino.

kapangidwe

Waukulu yogwira mankhwala lokonzekera imatengedwa suxamethonium mankhwala enaake. Ndiponso medicament zikuphatikizapo zigawo wothandiza monga sodium kolorayidi, asidi ethylenediaminetetraacetic disodium mchere (Trilon B), kapena disodium edetate, ndi madzi a jekeseni.

Fomu kumasulidwa

"Suxamethonium mankhwala enaake" kawirikawiri opangidwa ndi opanga mu mawonekedwe a njira (kwa onse mu mnofu ndi mtsempha).

zotsatira pharmacological

Akuti mankhwala ndi depolarizing minofu anasiya. Zimenezi ndi waufupi. The zigawo zikuluzikulu yogwira mankhwala mogwira kutsekereza kufala neuromuscular.

Miorelaxation nthawi zonse zimachitika mu ndondomeko yomweyo, m'pofunika kuganizira madokotala. Choncho, iwo amayamba ndi zaka minofu, zina zimakhudza minofu masticatory ndi minofu ya zala, maso ndi miyendo yonse. Ndiye minofu zosangalatsa ufikira m'khosi, masulani minofu ya kumbuyo, pamimba, ndipo timinofu. Latest anatani zochita za mankhwala minofu intercostal ndi zakulera.

Ngati mankhwala anali kutumikiridwa intramuscularly, kudzatenga zotsatira pambuyo awiri - mphindi zinayi, ndipo ngati mtsempha wa - pambuyo mphindi imodzi yokha. Zolemba malire minofu zosangalatsa chimachitika mu maminiti atatu pambuyo makonzedwe mankhwala. Amenewa kumatenga zisanu - maminiti khumi, malingana ndi mlingo wa thunthu.

mankhwala ndi uniformly anagawira mu madzi a m'magazi ndi madzimadzi extracellular chakachi akuluakulu a njira (anapereka makonzedwe mtsempha). Pafupifupi nainte peresenti hydrolyzed mankhwala, wodziwonetsa mu choline kapena asidi succinic. Malinga ndende ya cholinesterase mu magazi amasungidwa pa mlingo wokwanira, hafu ya moyo wa mankhwala ndi masekondi makumi asanu ndi anayi okha. thunthu ndi excreted kwathunthu ndi impso (kuphatikizapo chakhumi - zikutsatiridwa).

zikuonetsa

Akuti mankhwala ntchito milandu pamene chofunika kuti apange alowererepo kuti amafuna wathunthu minofu zosangalatsa. zinthu zimenezo zimaphatikizapo bronchoscopy, endoscopy, abdominanlnye ntchito muyike pena fractures, dislocations kuchepetsa ndi endotracheal intubation.

dosing

Thunthu "suxamethonium mankhwala enaake" angathe kuperekedwa kudzera m'mitsempha intramuscularly (monga kukapanda kuleka kapena bolus). Pakuti njira ntchito ntchito 0.1% njira ya mankhwala. Ntchito mlingo umene ndi suxamethonium mankhwala enaake ndi iodide aliyense payekha anatumizidwa katswiri malinga ndi makhalidwe munthu wodwala makamaka, ndipo kawirikawiri pamene kutumikiridwa m'nsinga osiyanasiyana monga 0,1 2 mamiligalamu pa kilogalamu, ndi mu mnofu - 3 kwa micrograms 4 pa kg. Mu wonse wa mankhwala buku okwana kulemera musalumphe micrograms zana ndi makumi asanu.

contraindications

Odwala ena Mulimonsemo sangathe atchule mankhwala "suxamethonium mankhwala enaake." Malangizo ntchito mankhwala monga contraindications zotsatirazi ntchito mankhwala: payekha hypersensitivity kuti zosakaniza aliyense wa medicament ndi, myasthenia gravis, bronchial mphumu, njingayo-kutsekedwa khungu, edema m'mapapo mwanga, hyperkalemia, zilonda hyperthermia, pachimake kwa chiwindi insufficiency, kobadwa nako ndi dystrophic myotonia, kusagwira cholinesterase, Duchenne akulu dystrophy, diso choipa makina. Komanso ankaona akuletsedwa ntchito mankhwala kwa ana ochepera chaka chimodzi ndi akazi pa Kubereka kapena yoyamwitsa.

zotsatira zoyipazi

Nthawi zina, "suxamethonium mankhwala enaake" (Anakonza jekeseni) zingachititse angapo zizindikiro zosasangalatsa ku kachitidwe zosiyanasiyana za thupi. Mwa makhalidwe amenewa, thupi lawo siligwirizana (mwachitsanzo, bronchospasm ndi anaphylactic mantha), ziwalo za minofu kupuma (kumachitika ngati pali matenda majini a mapangidwe seramu cholinesterase), arrhythmia, myalgia, malungo, bradycardia, hyperkalemia, hypersalivation, cardiogenic mantha, kutsitsa magazi, conduction zipolowe, kuthamanga intraocular. Kuti mupewe mavuto pamwamba n'kofunika kuti mosamalitsa kutsatira malangizo pa kagwiritsidwe ntchito ka mankhwala "suxamethonium mankhwala enaake." Mankhwala analogues (osachepera ena a iwo) ndi zotsatira yochepa kwambiri mbali. Choncho, nthawi zina zingakhale bwino kutsatira iwo.

ambiri osokoneza

Pankhani ya mwangozi kapena mwadala choposa mlingo kumachitika zotsatira zina osafunika wodwalayo. The owopsa awa ndi kutha kwa kupuma. Pankhaniyi popanda thandizo la ogwira ntchito sangathe kuchita mosiyana zingachititse kuti imfa. Akufunika mpweya wabwino. Nthawi zina seramu cholinesterase mlingo akutsikira kwambiri. Akatswiri ena amalangiza kuchitira chikhalidwe ichi kapena kuikidwa magazi atsopano, chomwe nthawi zambiri otetezeka mankhwala mmalo.

malangizo apadera

Ndi bwino kuti atchule apamwamba sanali depolarizing relaxants minofu kwa miniti patsogolo makonzedwe mankhwala "suxamethonium mankhwala enaake." Kufotokozera nkhani lili ndi mfundo zimene zimachitika ngati kumatha chiopsezo chitukuko wotsatira wa myalgia ndi minofu twitches. Nkofunika ntchito mankhwala okhawo m'madipatimenti apadera mabungwe zachipatala phunziro kwa kupezeka kwa zida zina zofunika (kuphatikizapo zida chifukwa kupuma yokumba) ndi ndodo woyenera akhoza kugwiritsa ntchito bwino njira imeneyi ndi zochita mavuto. Popeza ntchito ankaona njira zikhoza bradycardia mtima, Ndi bwino kuti atchule mankhwala kwa wodwala "atropine" pamaso ntchito "suxamethonium mankhwala enaake".

Kodi pamodzi ndi mankhwala ena

Pamene ntchito mankhwala ena nthawi yomweyo ankaona mankhwala ayenera kulabadira ngati mogwirizana amenewa ali ololedwa. "Suxamethonium mankhwala enaake" malangizo Buku si amalangiza ntchito zikufanana ndi kukonzekera antimiastenicheskimi monga kwambiri amachepetsa mphamvu ya zochita zawo. Akuti medicament komanso timapitiriza zotsatira mankhwala a glycosides. Mulimonsemo sangathe ntchito "suxamethonium mankhwala enaake" imodzi ndi magazi woperekayo, monga n'zothandiza hydrolysis anachita, mankhwala aliwonse magazi, njira soda ndi njira ya barbiturates ndi (amalimbikitsa precipitate).

Zotsatira pa kukhoza kuikira (galimoto ndi njira zovuta)

"Suxamethonium mankhwala enaake" amakhudza kwambiri pa luso kuganizira ndi kukhala tcheru. Izi zikutanthauza kuti apewe ngozi kupewa galimoto ndi ntchito ina iliyonse imene loopsa moyo ndi thanzi la munthu komanso amafuna ndende mkulu ndi zochita mwamsanga ndi nthawi posankha zochita pa tsiku loyamba pambuyo kuchotsa mankhwala ankaona.

zinthu yosungirako ndi moyo alumali

Khalani "suxamethonium mankhwala enaake" Mwina angakhale zinthu mosamalitsa kumatanthauza. Ndiko kuti, kutentha yosungirako ayenera osiyanasiyana monga awiri eyiti madigiri Celsius. mankhwala adzaikidwe kunja m'dera kupezeka kwa ana. The pazipita alumali moyo wa mankhwala ndi zaka zitatu kuchokera tsiku kupanga. Itatha nthawi iyi ntchito mankhwala ali osavomerezeka, chifukwa Pankhaniyi wotaya katundu opindulitsa ndi n'koopsa wodwalayo.

chitetezo wodwala, chitetezo cha moyo wake - ndi udindo madokotala amene zikugwira mankhwala ake. Choncho, n'kofunika kwambiri kuti atsogoleri a mabungwe zachipatala mbamphedza kwa ogwira ntchito mabungwe awa ndi aluso pa ntchito mankhwala, mavuto a ndalama izi, njira kuchotsa zochita chilichonse choopsa. Mofananamo, ogwira ntchito m'chipatala ayenera kudziwa zofunika ndi luso bwino zipangizo alipo angapulumutse moyo wa wodwalayo. Zimenezi zikugwira makamaka kukonzekera amene angathe mavuto angasokoneze isanayambike imfa. Ndi kwa gulu ili la mankhwala monga "suxamethonium mankhwala enaake." Choncho, ayenera kugwiritsidwa ntchito kukachitika kuti pa ndondomeko pali akatswiri woyenera amatha kugwiritsa ntchito makina othandiza. Izi zikhonza kukhala zofunika pamene mbali anachita monga kumangidwa kupuma. Pankhaniyi, kugwirizana zochita madokotala ndi wokhoza awo katswiri adzakhala zinthu kwambiri kuti aone ngati wodwala adzapulumuka.

Nthawi zina madokotala pazifukwa zina (ngati pali ena contraindications) kusankha kugwiritsa ntchito minofu anasiya - analogi "suxamethonium mankhwala enaake" (mwachitsanzo, "Ditilin" amene sakhoza okhawo pamaso pa khungu). Nkofunika kudalira maganizo odalirika a akatswiri pa nkhani imeneyi. Choncho muyenera onetsetsani yamtunduwu akatswiri a madokotala amene inu kugwirizana.

Musanayambe kusankha chiphunzitso pano ayenera kuphunzira za nkhani "suxamethonium mankhwala enaake": dzina malonda, analogs, contraindications, chingachitike mbali, ntchito, ndi mlingo analimbikitsa. Wodwala ayenera kuphunzira zingwe wotani mankhwala anali kuwalanga. "Listenon" ( "suxamethonium mankhwala enaake") - malonda dzina la thunthu mu funso. Choncho, pamene inu mumva pa milomo ya dzina ili dokotala, mudzakhala bwino za mmene zinthu thupi lanu. Kudziwa zimenezi n'kofunika kuti kupeŵa miyoyo yawo pangozi zosafunika. Nkofunika kukhala wosamala zimene mankhwala inu tikuuzidwa mu mankhwala.

Kukhulupirira thanzi lanu yekha kuti akatswiri, kusankha wapamwamba kwambiri chithandizo ndi zinthu zabwino! Dzisamalire!