"Metadoxil": ndemanga za zidakwa, malangizo ogwiritsidwa ntchito, zolemba ndi kufotokozera

Kodi mankhwalawa ndi otani "Metadoxil"? Ndemanga za zakumwa zoledzeretsa, mtengo wa mankhwalawa ndi kuwerengedwera kwake tafotokozedwa pansipa. Komanso kuchokera mu nkhani ino mudzaphunzira za njira yogwiritsira ntchito mankhwalawa, zotsatira zake ndi zotsutsana.

Mafotokozedwe, mawonekedwe, maonekedwe

Mankhwalawa "Metadoxil" (ndemanga za zidakwa za izo zidzafotokozedwa pansipa) akupitirira kugulitsidwa mu mawonekedwe otsatirawa:

• Biconvex ndi mapiritsi oyera oyera omwe ali ndi chiopsezo kumbali imodzi ndi kulembera dzina la mankhwala - pamzake. Chigawo chake chogwira ntchito ndi pyridoxine L-awiri pyrrolidone zisanu-carboxylate kapena otchedwa metadoxine. Zimaphatikizanso MCC ndi stearate ya magnesium.
• Njira yowonongeka ya jekeseni popanda mtundu kapena ndi tinge yachikasu. Cholinga chake chachikulu ndi metadoxine. Kuwonjezera apo, mankhwalawa ali ndi mpweya wa sodium, madzi, sodium metabisulfite ndi methyl-parahydroxybenzoate.

Zotsatira za mankhwala

"Methodoxil" ndi mankhwala oledzera. Ndiponso wothandizira amasonyeza detoxification ndi hepatoprotective katundu.

Mmene mankhwalawa amathandizira mankhwalawa ndi chifukwa cha nembanemba. Komanso, mankhwalawa amatha kubwezeretsa chiŵerengero chaulere unsaturated ndi chodzaza mafuta acids. Chotsatira chake, kukana kwa hepatocyte kumakhudza mafuta a peroxide owonjezera a mafuta, omwe amapezeka pamene mawonekedwe a poizoni amakhudzidwa, akuwonjezeka.

Mankhwalawa amachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda, zomwe zimagwiritsanso ntchito metabolism ya ethanol (makamaka acetaldehyde dehydrogenase ndi mowa dehydrogenase), yomwe imafulumira kwambiri kuchoka m'thupi, motero imachepetsa poizoni.

Mbali za mankhwala

Ndi chiyani chodabwitsa pa mankhwala "Metadoxil"? Malangizo, ndemanga imanena kuti mphamvu yake yogwira ntchito imalepheretsa mapangidwe a zinthu monga collagen ndi fibronectin, komanso imalepheretsa kuwonjezeka kwa triglycerides, zomwe zimachepetsa kwambiri kukula kwa chiwindi cha chiwindi.

Tiyeneranso kukumbukira kuti chida ichi chikufupikitsa nthawi yochotsa matenda, kuti athe kuchepetsa matenda omwe amachititsa kuti matendawa asinthe.

Mmodzi sangathe kunena kuti metadoxine imayambitsa machitidwe a GABA-ergic ndi cholinergic neurotransmitter, amalepheretsa kuyendetsa galimoto, kumapangitsa kukumbukira pang'ono ndi kuganiza. Kuwonjezera apo, mankhwalawa amatha kukhala ndi nkhawa zopanda mphamvu komanso zowonongeka, komanso kuchepetsa chilakolako cha mowa.

Kinetics

Mutatha kumwa mankhwala mkati mwake, umathamanga msanga kuchokera m'matumbo. Metadoxine ili ndi bioavailability (pafupifupi 60-85%). Zomwe zimamanga plasma mapuloteni ndi 50%.

Chigawo ichi chimagwiritsidwa ntchito mophiphiritsira pachiwindi popanga mapangidwe othandizira - pyrrolidone carboxylate ndi pyridine.

Theka la moyo wa mankhwalawa pa marenteral administration kapena ingestion ndi 45-57 mphindi. Pafupifupi 40-50% ya mankhwalawa amachotsedwa pamodzi ndi mkodzo masana ndi pafupifupi 35-50% ndi nyansi zofiira, kwa maola 95.

Zisonyezo

Pansi pazimenezi ndi mankhwala ogwira ntchito kwambiri "Metadoxil"? Olemba mowa amasonyeza kuti chida ichi ndi chabwino:

• Kusuta mowa mopitirira muyeso;
• Pa zovuta za matenda a chiwindi, kuphatikizapo zakumwa zoledzera;
• Matenda ochotsera mowa ;
• Mowa mwauchidakwa, kuphatikizapo zovuta.

Contraindications

Mankhwala omwe ali mu funsowa akutsutsana ndi:

• Kuyamwitsa;
• Kubereka kwa fetus;
• Kumvetsetsa kwakukulu kwa zinthu za mankhwala.

Mwachidziwitso, mankhwalawa ayenera kuperekedwa kwa matenda a Parkinson, makamaka ngati wodwala akugwiritsa ntchito levodopa kale. Izi ndi chifukwa chakuti metadoxine ikhoza kuchepetsa mphamvu ya wotsiriza.

Mankhwalawa "Metadoxil": malangizo othandizira

Ndemanga imati wothandizira ayenera kugwiritsidwa ntchito pokhapokha atakambirana ndi katswiri.

Pamene mowa umaledzeretsa, makamaka kwambiri, mankhwalawa amaperekedwa intramuscularly pa 300-600 mg kapena intravenously - 300-900 mg.

Ndi ma intravenous administration, mlingo woyenera wa mankhwalawo umachepetsedwa mu 5% yothetsera dextrose kapena 500ml ya sodium chloride. Mu mawonekedwe awa, mankhwalawa amathandizidwa kutayira, kwa maola 1.4.

Kuphatikizidwa kwa matenda a chiwindi, komanso kuledzeretsa kwachilendo, mankhwalawa amaperekedwa kwa 500 mg kawiri pa tsiku kwa mphindi 25-35 asanadye. Mlingo uwu ukhoza kuwonjezeka kufika 500 mg katatu patsiku.

Maphunziro a mankhwalawa ndi mankhwalawa ayenera kukhala osachepera masiku 90.

Pamene mankhwala osokoneza bongo amamwa mankhwala osokoneza bongo omwe amawathira mazira 900 mg kamodzi pa tsiku kwa masiku 3-7 (malinga ndi chikhalidwe cha wodwalayo).

Zovuta zochitika

Kodi zotsatira zovuta za mankhwalawa ndi "Metadoxil" ndi chiyani? Maphunziro a oledzeretsa amanena kuti pamene akugwiritsa ntchito mankhwalawa nthawi zambiri amakhala ndi zotsatira zolakwika.

Tiyeneranso kukumbukira kuti mwa anthu omwe ali ndi mphumu yothamanga, bronchospasm ikhoza kuchitika (nthawi zambiri mukamagwiritsa ntchito yankho).

Mfundo Zapadera

Mu njira ya jekeseni, "Metadoxil" ili ndi gawo monga sodium metabisulfite. Izi zimayambitsa zotsatira zowonongeka kwa anthu omwe amayamba kusokoneza chifuwa cha mphumu, komanso kuwalimbikitsa.

Mankhwalawa "Metadoxil": ndemanga za zidakwa

Tsoka ilo, palibe ndemanga zambiri zokhudzana ndi mankhwala "Metadoxil". Komabe, kuchokera kwa otsalira ndi anthu omwe amamwa mowa mwauchidakwa, tingathe kunena mosapita m'mbali kuti mankhwalawa amathandiza kwambiri kuchiza kudalira mowa.

Pankhani yothandiza kuchipatala , maganizo a odwala amasiyana kwambiri. Ena amati ndi matendawa, mankhwalawa amathandiza bwino, pamene ena - sanaone zotsatira zake.

Palinso mauthenga ambiri oipa pa mtengo wa mankhwalawa. Monga lamulo, ndi 1250-1450 rubles.