Mankhwala 'Pipolphen'. Malangizo ogwiritsidwa ntchito

Imodzi mwa mankhwala ogwiritsira ntchito antiallergic, omwe amagwiritsidwa ntchito posachedwa - "Pipolphen". Malangizo ogwiritsira ntchito alipo mu bokosi lirilonse la mankhwalawa, mosasamala kanthu kuti amatulutsidwa mu dragee kapena mwa njira ya njira yothetsera intravenous / kapena intravenous administration. Mafunde a Pulpofen amafanana ndi mphutsi zooneka bwino, ali ndi nkhope yowala kwambiri yomwe ili yobiriwira komanso yopanda phokoso. Njira yothetsera jekeseni ndi yosaoneka bwino, nthawi zambiri imakhala yopanda mtundu, koma nthawi zina ikhoza kukhala ndi tinge yobiriwira, sikununkhiza.

Chifukwa chakuti phukusi lililonse muli malangizo oti agwiritse ntchito "Pipolphen" kukonzekera, anthu amatha kuphunzira ntchito ya mankhwala ya mankhwala. Mankhwala othandiza a mankhwalawa ndi promethazine. Ndizochokera ku phenothiazine, yomwe imadziwika ndi ntchito yaikulu ya antihistamine. Promethazine mofulumira komanso mogwira mtima imakhudza dongosolo lachithupi la umunthu la munthu: ilo liri ndi chithunzithunzi, chowongolera, antipsychotic, antiemetic ndi hypothermic action, ndipo chimalimbikitsa ndi kulepheretsa hiccups.

Mankhwalawa "Pipolphen" amaletsa (koma samathetseratu) zotsatira za mbiri ya histamine, kuphatikizapo kuyabwa ndi ming'oma. Zochita za anticholinergic zimayambitsa kuyanika pamatenda a m'mphuno ndi pamlomo.

Zochita za Promethazine antiemetic zimakhala chifukwa cha kuchepa kwa zinthu zomwe zimapangitsa kuti zinthu zikhale zosangalatsa, zomwe zimapangitsa kuti anthu asagwiritsidwe ntchito, komanso kuti asamayende bwino m'madera ena a medulla oblongata.

Mankhwalawa amachititsa kuti mankhwalawa asokoneze mbiri ya histamine-N-methyltransferase ndipo amalepheretsa mbiri ya histaminergic pakati. Kuonjezera apo, promethazine ikhoza kuletsa acetylcholine ndi serotin receptors, ndipo, mwa kulimbikitsa al-adrenergic receptors, mwachindunji amalepheretsa chidwi cha maonekedwe a ubongo. Mphamvu yolimbana ndi matenda a promethazine imakhala yofooka kuposa ya antipsychotic phenothiazines, chifukwa ndi yopambana kuposa antipsychotic phenotiazines. Zida zawo zimasiyana kwambiri. Pachifukwa ichi, pamene mutenga mankhwala mankhwalawa, promethazine alibe vuto lililonse pamaganizo a mtima.

Malangizo ogwiritsidwa ntchito pokonzekera "Pipolphen" amakulolani kuti mudziwe kuti zotsatira za kuchipatala za mankhwalawa zimayamba kuonekera pambuyo pa maminiti awiri (ngati mankhwalawa akuyendetsedwa mosagwira ntchito) kapena pambuyo pa mphindi zisanu (ndikukhala ndi intravenous administration). Zotsatira za mankhwala zimakhala pafupifupi maola asanu, koma nthawi zina zimatha maola 12.

Malangizowo, omwe amapangidwa ndi kukonzekera "Pipolphen", amapereka mpata kuti adziŵe zizindikiro zogwiritsira ntchito mankhwala:

- Mawonetseredwe alionse a matenda oopsa, kuphatikizapo rhinitis, urticaria, pollinosis, matenda a serum, kuyabwa, angioedema, conjunctivitis;

- ndi chithandizo chothandizira cha machitidwe a anaphylactic;

- kusanza kapena kunyozedwa chifukwa cha anesthesia kapena kuwonekera pambuyo pa opaleshoni;

- amagwiritsidwa ntchito ngati chiwonongeko pa nthawi yotsatila kapena yowonongeka;

Ululu umene umapezeka pambuyo pa opaleshoni;

- kuthetsa kapena kuletsa chizungulire ndi mseru chifukwa choyenda paulendo.

Komabe, ziyenera kukumbukiridwa kuti palinso zotsutsana ndi kumwa mankhwala "Pipolphen". Malangizo ogwiritsira ntchito amakulolani kuti mudziwe za iwo mu nthawi:

- vuto lomwe limakhalapo ndi kuvutika kwakukulu kwa kayendedwe kabwino ka mitsempha;

- kusanza kwa majeremusi osadziwika, omwe amapezeka mwachisawawa kwa ana;

- kugwiritsa ntchito mowa panthawi imodzi, mankhwala osokoneza bongo, mankhwala osokoneza bongo;

- Miyezi iwiri yoyambirira ya moyo wa mwanayo;

- kuyamwitsa ndi mimba;

- Galaucoma yowatsekedwa.

Nthawi zina, mankhwalawa akapezeka, zotsatira zake zimachitika. Kawirikawiri, kutsekemera kwa "Pipolphen" kumachitika. Malingaliro a anthu omwe amamwa mankhwalawa akhoza kukuthandizani zambiri zokhudzana ndi milandu yotereyi.