Mankhwala "Gynestril": malangizo ntchito, analogs ndi ndemanga

Kodi kutenga mankhwala "Gynestril"? Malangizo ntchito mankhwalawa adzakhala kutchulidwa zipangizo za nkhaniyi. Mu izo, ife kudzapereka mayankho odwala, mankhwala, makhalidwe ake pharmacological, zizindikiro ndi contraindications.

The zikuchokera, mawonekedwe

Kodi zigawo zikuphatikizapo mankhwala "Gynestril"? The Malamulo linalanda ntchito njira imeneyi, ndi kuti pophika ake yogwira ndi mifepristone. Ndiponso medicament limapangidwa zosakaniza zina mwa mawonekedwe a mbatata wowuma, lactose, microcrystalline mapadi, povidone, magnesium stearate ndi wowuma ndi sodium carboxymethyl.

Kugula mankhwala akhoza kukhala mapiritsi omwe mmatumba mu mapaketi a makatoni.

Pharmacological makhalidwe mankhwala

Kodi mukudziwa kuti ndi mankhwala "Gynestril"? Malangizo ntchito adzakuthandizani kumvetsa mfundo ya kanthu za mankhwala, ndipo Adzakuuzani kuti palibe zizindikiro za ntchito zake yochizira matenda.

Ankaona medicament ndi steroid wothandizila antigestagens chiyambi kupanga. The achire efficacy wa mankhwala chifukwa kapangidwe kake.

Pa chiphaso cha mifepristone mu thupi la munthu kuti kumabwezera mmbuyo zotsatira za progesterone, koma kuonetsa ntchito progestational.

Akatswiri onani chidani mankhwala chifukwa mpikisano glucocorticoid kumanga pa mlingo cholandilira.

Monga amadziwika, udindo waukulu mu mapangidwe leiomyoma uterine kuperekedwa kwa mahomoni wamkazi, makamaka progesterone. Pa nkhani imeneyi, mifepristone awerenge wodwala kuti ndigwire progesterone cholandilira. Chifukwa cha mankhwala kumachitika chotupa kukula yomweyo, komanso kuchepetsa kukula kwa fibroids , ndi uterine.

The pharmacokinetic katundu wa mankhwala

Tchulani ali pharmacokinetic mankhwala "Gynestril"? Malangizo, ndemanga anakumana madokotala kuti pambuyo makonzedwe m'kamwa ndende apamwamba mankhwala zimawonedwa pafupifupi 80 Mphindi. Komanso, bioavailability ake ndi 69%.

Madzi a m'magazi mapuloteni ankaona mankhwala chimamanga 98% (ndi albumin ndi alpha-1 asidi glycoprotein).

Pambuyo gawo yogawa kumachitika pang'onopang'ono Kupha gawo. Mu ndende mwazi wa mankhwala yafupika ndi theka (pakati pa maola 15 ndi 72).

Kucotsa mankhwala mofulumira, ndi nthawi ya maola 18.

zikuonetsa

Kumene mankhwala "Gynestril" awerenge? Malangizo ntchito, akatswiri enieni amati zizindikiro zotsatirazi:

• mankhwalawa leiomyoma uterine;
• kuchotsa mimbayo intrauterine masiku 42;
• kupatsidwa ulemu (kapena kukondoweza) ntchito (kuphatikizapo pa akuti);
• mwadzidzidzi kulera (postcoital) kwa kusadalirika ntchito kulera zosiyanasiyanazi, ndipo mu nthawi kugonana kutachitika mosadziteteza kugonana.

contraindications

"Gynestril" mankhwala kwa mimba sayenera kugwiritsidwa ntchito pamene:

• kukomoka zosatsimikiza mimba;
• chovomerezeka ectopic pregnancy;
• mimba zomwe zinachitika pambuyo achire njira m'thupi kulera zosiyanasiyanazi, kapena ntchito kulera zosiyanasiyanazi intrauterine;
• mimba patapita masiku 42.

Pamene leiomyoma mankhwala ndikoletsedwa Ndinapereka milandu zotsatirazi:

• kuwayika pa mfundo submucous myoma;
• mu zotupa yamchiberekero;
• endometrial hyperplasia;
• ngati leiomyoma mtengo waukulu.

"Gynestril" Mapale kwa kupatsidwa ulemu ntchito sanagwiritse ntchito:

• aakulu preeclampsia;
• nthenda yoopsa ulaliki;
• chisanadze eclampsia;
• eclampsia;
• asanakwane kapena pambuyo akuti mimba;
• imbalances kukula kwa yoopsa mutu ndi amayi mafupa a chiuno;
• undiagnosed zoonera ku kapepala maliseche pa gestation.

Kodi onse contraindications mankhwala "Gynestril"? Malangizo limapereka pa funso limeneli ndi inde. Ziletsozi zikuphatikizapo zinthu zotsatirazi:

• porphyria;
• yaitali mankhwala ndi glucocorticoids;
• aakulu magazi m'thupi;
• aimpso kapena kulephera chiwindi (mtundu uliwonse);
• kuphwanya hemostasis (zapitazi anticoagulant mankhwala);
• extragenital kwambiri chikhalidwe;
• kudwala a dongosolo wamkazi ubereki, chomwe ndi khalidwe yotupa;
• hypersensitivity (kuphatikizapo mbiri);
• nikotinozavisimost, makamaka zaka 35.

Ndi kusamala kwambiri pamene mankhwala awa:

• matenda obstructive m'mapapo mwanga (khalidwe aakulu);
• mtima kulephera;
• oopsa;
• arrhythmia;
• bronchial mphumu;
• mtima mungoli chisokonezo.

Mankhwala "Gynestril" mawu

Pakuti kuchotsa mimbayo (ndemanga za medicament izi mtima ayankhidwa pang'ono zina), mankhwala ayenera kuperekedwa kokha katswiri yopapatiza. Ndipo kupitiriza kumwa miyala Pankhaniyi yekha pamaso pa gynecologist a.

Popeza ntchito mankhwala "Gynestril"? Malangizo mimba kuchotsa limanena kuti m'pofunika kugwiritsa ntchito mlingo umodzi wa 600 mg.

Mankhwala akutengedwa pa maola 1-1.5 kudya ndi kusamba pansi ndi 100 ml ya madzi.

Kuonjezera efficacy wa mankhwala mulole patsogolo zolinga 400 mg misoprostol (i.e., ndi kupanga prostaglandin E1).

Atalandira mapiritsi wodwala ayenera kuyang'anira azamba maola osachepera awiri. Patapita masiku 1.5 kapena 2 anagwira ultrasound. Ngakhale pambuyo masabata 1-2 kuchita kuona matenda ndi ultrasound mobwerezabwereza ndipo fufuzani milingo magazi a hCG kutsimikiza padera.

Zikatero, ngati mankhwala sadamuthandize (ie, mimba akupitiriza), dotolo akuonetsa wosatsogoleredwa kukhumba kuti liwunikidwenso (histology) zotsatira za ndondomeko.

Yotithandiza ntchito generic, mankhwala kamodzi kutumikiridwa mu mlingo wa 200 mg. Amachita zimenezi pamaso pa gynecologist a. Pakatha tsiku limodzi, mlingo wa mankhwala akubwerezedwa pa mlingo chomwecho.

Patapita masiku 2-3, amanena yowonjezera ngalande kubadwa. Choncho kudziwa kuti n'zotheka ntchito zina "oxytocin pamene" kapena prostaglandins.

Koma uterine leiomyoma ntchito mankhwala "Gynestril"? Guide limanena kuti kukonzekera matenda amenewa nthawi kutumikiridwa mu mlingo umodzi wa 50 mg. Mankhwala akutengedwa pakamwa kwa miyezi itatu.

Pankhani kulera pambuyo coital, madokotala kulengeza ntchito ya medicament m'nkhani ndalama ya 10 mg pa masiku atatu pambuyo kugonana mosadziteteza kugonana (kaya gawo kusamba). Mukumwa mapiritsi mu nkhani iyi ndi zofunika kwa maola awiri patsogolo kapena pambuyo chakudya.

Nthawi cha mankhwala osokoneza bongo

Gwiritsani ntchito mankhwala pa mlingo wa magalamu oposa awiri a zimayambitsa zotsatira zoipa. Pamene ntchito kuposa ndalama mwachindunji mankhwala wodwala akhoza kupanga adrenal insufficiency, chimene chimafuna mankhwala symptomatic.

zotsatira zoyipazi

Kulandira medicament "Gynestril" Nthawi zambiri amayambitsa zotsatira ngati mbali monga mutu, nseru, chizungulire, kusanza, zotupa m'mimba, amenorrhea, lohiometra zoonera, subinvoljutcija uterine, hyperthermia, emmeniopathy, kufooka, maganizo a kutupa kwa chiberekero ndi zokhudzana, ululu komanso ululu pamimba. Ngati muli ndi zizindikiro zimenezi, onetsetsani kukaonana ndi dokotala.

Mwanjira mankhwala

Iwo ali osavomerezeka kutenga mankhwala "Gynestril" limodzi ndi NSAIDs. Iwo ayenera kukumbukira kuti osakaniza glucocorticoids m'pofunika kuwonjezera mlingo, koma atakambilana ndi dokotala.

ayamikira yeniyeni

Iwo ali osavomerezeka kuti makhwalawa monga kulera zosiyanasiyanazi zonse.

Pamene inu ntchito "Gynestril" Kuona inayenera kuuza wodwala za options ena a njirayi, makamaka ngati pambuyo masabata awiri mimba akupitiriza kapena pali mimba chosakwanira (zotheka chiopsezo kuvutika mu mwana wosabadwayo).

Price ndi analogues ndalama

Analogs "Gynestril makonzedwe" mankhwala ndi mankhwala zotsatirazi: "Ginepriston", "Penkrofton", "Agesta" "Mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Price ankaona mankhwala ndi mkulu ndipo chimachititsa 5000-6000 rubles.

Reviews a medicament

Lomveka mosabisa zabwino kapena zoipa ndemanga za "Gynestril" palibe kukonzekera. Komabe, odwala ambiri amvetsera za chida ichi. Iwo amanena kuti ndi othandiza kwambiri ndipo ndi bwino kuti phwando.

Iwo ayenera kukumbukira kuti anthu ena M'malo mwake, nthawi zambiri anamuona chitukuko mavuto.

ndemanga onsewa amanena kuti zakudya za mankhwala zizichitidwa yekha atakambirana ndi dokotala.