Malangizo ntchito "tiapridal". Analogs ndi ndemanga

"Tiapridal" - mankhwala antipsychotic chopangidwa ndi tiapride. mankhwala umagwiritsidwa ntchito monga sedative, analgesic ndi zachinyengo. Maziko a kanthu antipsychotic - kutsekereza dopamine zolandilira, amene kwambiri bwanji kugwira ntchito kwa CNS. M'nkhaniyi tiona kufotokoza mwatsatanetsatane za mankhwala.

Zikuchokera kupanga mankhwala

Mankhwalawa amapezeka m'njira ziwiri, phale zikhoza kugulidwa ndi njira:

• piritsi limodzi monga ampoule munthu limapangidwa 100 mamiligalamu wa chigawo chachikulu ndi zinthu wothandiza. Pamene zosakaniza wothandiza ntchito zikuchokera povidone, magnesium stearate, mannitol. The zikuchokera amadziwikanso wodzilemekeza ndi amadzimadzi colloidal dioxide, pakachitsulo ndipo microcrystalline mapadi.
• Kupatula pa chigawo chachikulu cha njira limapangidwa sodium kolorayidi ndi madzi a jekeseni.

Mu bokosi lina munali miyala 20 (2 matuza ndi miyala 10) kapena mbale 12 (2 matuza 6 mbale). Malangizo ntchito "Tiapridal" mu mawonekedwe a njira jekeseni amalola kutumikiridwa kudzera m'mitsempha intramuscularly. Izi mawonekedwe a mankhwala ndi oyenera okha zochizira odwala wamkulu.

Pharmacodynamics "tiapridal"

The medicament ali neuroleptic, analgesic ndi kanthu anxiolytic. Monga Buku malangizo, "Tiapridal" kusankha midadada kugwira ntchito D ₂ maselo a dopamine chapakati. Choncho pa D ₁ zolandilira alibe chochita. mankhwala kamakhala kuchotsa psoriasis, pamene ntchito okalamba bwino kuganiza.

Pharmacokinetics "tiapridal"

Dongosolo mu mnofu wa mankhwala (200 mg) wa msinkhu wake pazipita mu thupi wapezeka pambuyo pa maminitsi 30, kugwiritsira ntchito mapiritsi pa mlingo chomwecho - mphindi 60. The bioavailability wa mankhwala pamene ntchito asanalankhule chakudya ndi 75% ziwonjezeke kwa 95%. Chifukwa mankhwala umachuluka ngati ntchito ndi mlingo wake pazipita mu chamoyo (40%).

Mayamwidwe mu thupi msanga odwala okalamba. "Tiapridal" malangizo ntchito amatanthauza m'mwamba mitanda ya placental ndi magazi ubongo zotchinga. Amadziwika kuti pamene mankhwala mankhwala alipo mu zikuchokera mkaka wa m'mawere. Mu akazi, kuchotsa tsankho la mankhwala msanga kuposa amuna (pa 2.9 Nchito maola), kusiyana ndi maola 0,7. Kagayidwe yodziwika monga zolimbitsa. Mbali yaikulu ya mankhwala (70%) ndi m'thupi ndi impso sichinasinthe.

Zikuonetsa "Tiapridal" kukonzekera

Kuti litsatira mankhwala ndi mankhwala "Tiapridal" kuwerenga motere:

• dyskinesia (tardive, mowiriza);
• Gilles de A La Tourette syndrome;
• chorea;
• matenda khalidwe (aukali boma, mukubwadamuka neri Al.), chifukwa mu otaya yokulirapo ya uchidakwa aakulu ndi odwala okalamba;
• mawonetseredwe zoipa makhalidwe, monga boma mwamakani ndi mafunde;
• ululu khalidwe tima (mawonekedwe aakulu).

Contraindications, sitingathe kulandira "Tiapridal" mankhwala

Imaletsa imposition wa "Tiapridal" malangizo ntchito ana amene zaka zosakwana zaka zisanu ndi chimodzi. Mu mankhwala Dokotala ikuchitika mankhwala okha. Mankhwala sayenera akazi apakati ndi Odwala amene yoyamwitsa. Mankhwala si ntchito ngati hypersensitivity kwa zigawo zake, ndi njira zina. Contraindications monga limati ngati:

• kwa chiwindi ndi kulephera aimpso, amene ali mwamphamvu ndithu;
• prolaktinzavisimogo Kupeza Vuto zotupa, kukayikirana cha kukhalapo kwake;
• hypertensive mavuto;
• matenda a pheochromocytoma, ndi kukayikirana linakhalapo.

Mapiritsi ndi njira ntchito limodzi ndi "sultopride" ndi dopamine cholandilira agonists (kupatulapo ndi chithandizo cha odwala matenda Parkinson) sali pamodzi mitundu ina ya neuroleptics, odana arrhythmic nthumwi za thupi makalasi Ine ndi III A.

Mankhwala "Tiapridal" malangizo salola imodzi ntchito "Moxifloxacin", "sparfloxacin", "Difemanila", "mankhwalawa", "bepridil," "mizolastine", "levodopa", "cisapride" ndi mtsempha "vincamine" .

Ngati wodwala (makamaka achikulire) kuchitiridwa ndi mankhwala zingachititse kuti chitukuko cha hypokalemia, mtima conduction kuwonongeka, kutalikitsa QT imeneyi, pakutchulidwa wa bradycardia anasonyeza khalidwe, ntchito "Tiapridal" ayenera kukhala mosamala. Chenjezo chofunika Zikatero:

• matenda Parkinson;
• kobadwa nako QT imeneyi elongation khalidwe;
• hypokalemia;
• aakulu aimpso kulephera;
• bradycardia;
• matenda amene akusokoneza dongosolo mtima (decompensation sitepe);
• khunyu.

Mankhwalawa "Tiapridal"

pa ntchito "Tiapridal" Buku amalimbikitsa ntchito yoyamba Mlingo yaing'ono, pang'onopang'ono kuwonjezeka iwo, kuti akakhale zotsatira pazipita.

matenda khalidwe

Mpumulo awo m'pofunika kutsatira 200 mg wa mankhwala tsiku (mpaka 300). Ubwino zimatheka mu masabata asanu pa avareji. odwala achikulire kutumikiridwa mlingo m'munsi mankhwala - 50 mg. A mlingo umodzi ayenera kudyedwa kawiri patsiku, ndi kuwonjezeka ake amaloledwa kugwilizana ndi imeneyi yake, zochitika imagwiridwa pang'onopang'ono, kutenga malangizo nkhani Katswiri. Mlingo tsiku sayenera upambana 300 mg.

Matenda anapwetekedwa

Mlingo tsiku la mankhwala mankhwala zinthu zimenezi ndi 200 400 mg.

Chorea, syndrome Gilles de A La Tourette

Pamene tikugwira mankhwala a mwana tsiku mlingo amusankha kutenga nkhani za thupi ndi za 3-6 mg / kg. Ngati mukufuna kuchita ndi mankhwala wamkulu, choyamba ntchito 25 mg wa mankhwala patsiku, kenako (pambuyo kuwonjezeka pang'onopang'ono mlingo) - 300-800 mg.

Mukubwadamuka, mokwiya

Analimbikitsa mlingo tsiku la medicament ndi 100 mpaka 150 mg.

matenda khalidwe

The mlingo ntchito usana (200 300 mg) pa nkhani ya limati delirious kapena predelirioznogo limatuluka kuti 400-1200 mg. The pazipita zotheka mlingo umene siziyenela, ndi 1800 mg. Mawu oyamba a mankhwala opangidwa pafupifupi aliyense asanu maola. Ngati mankhwala koyenera kuti munthu okalamba, tsiku lililonse 2-3 jakisoni pakati zomwe anaona imeneyi maola 6. Zochizira odwala ngati akulimbikitsidwa kudya tsiku la mg ndi 200 mpaka 300 a medicament pa nthawi amaloledwa kulowa zosakwana 100 mg "tiapridal".

Nacho mawu a chikhalidwe aakulu a ululu

Njira zochokera wovulala mlingo tsiku lolingana 200-400 mg wa mankhwala.

Zotsatira zoyipa za mankhwalawa pamene mukumwa "Tiapridal" mankhwala

Popereka chithandizo cha mankhwala "Tiapridal" malangizo Buku, ndemanga kutsimikizira mosavuta zochita zina chokhwima. Violation kumachitika mu urogenital ndi chonena, endocrine ndi machitidwe a mtima. Komanso pali mavuto ndi maganizo. Zotsatira zina zoipa monga chifuwa, mawonetseredwe khungu limodzi ndi kunenepa, orthostatic hypotension.

Ambiri osokoneza "tiapridal"

Ngati inu ntchito kwambiri mlingo zotheka ambiri osokoneza ndi zizindikiro zake monga zipolowe za chikumbumtima, ndi lalikulu kwambiri limene - chikomokere, neuroleptic syndrome (zilonda, pachimake mitundu). Pofuna kuthetsa mkhalidwe wa chamoyo ikuchitika chithandizo zochokera wothandizila anticholinergic. Pambuyo chiyembekezo chakuti ya mankhwala zofunika kuchita mankhwala symptomatic ndi plasmapheresis.

Kusamala

Pamaso ntchito mankhwala "Tiapridal" malangizo Buku akuonetsa kuti kukonza hypokalemia. Pa mankhwala n'kofunika nthawi zonse kuwunika electrolyte malire kuchititsa electrocardiogram, kuyan'ana kusintha matenda chithunzi.

Ngati m'pofunika kutsatira anticholinergic mankhwala zotsatira kulandira neuroleptics extrapyramidal syndrome anayamba m'malo dopamine cholandilira agonist.

Pa nthawi yolandira chithandizo ayenera kusiya zinthu zimene loopsa kuthekera, si analimbikitsa kuchita ntchito yofunika kusamalidwa ndi sanafike msanga.

Mogwirizana ndi zinthu zina

Ena kukonzekera osakaniza ndi kumwa mankhwala "Tiapridal" malangizo, maganizo kugwirizana ndi Mwina yatsoka mosiyanasiyana zoipa. Iwo ali osavomerezeka pa chithandizo ntchito "Clonidine", mankhwala, anxiolytics, barbiturates ndi opioids, monga "tiapridal" zotsatira adzakhala kutchulidwa. Chifukwa zosagwirizana sayenera kumwedwa "levodopa" ndi mowa. Mankhwala akhoza pamodzi ndi ntchito neurotrophic mankhwala, analgesics, antidepressants, neuroleptics. Mkulu chiopsezo orthostatic hypotension, pali ntchito munthawi yomweyo mankhwala antihypertensive ndi "Tiapridalom".

Mtengo wa analogues mankhwala, ndemanga za mankhwala "Tiapridal"

Ngati ndi kotheka chithandizo "Tiapridal" amatanthauza malangizo kufotokoza tiyeni mukudziwa zimene mankhwala ndi. Mtengo wa mankhwala n'kofunika kwambiri kusankha ndi medicament mankhwala. The yothetsera mu mbale akhoza kugulidwa kwa 995 rubles, ndi miyala - chifukwa 1,400 rubles.

Pakati pa analogues wa mankhwala - "Eglonil", "Betamax". Wa mmalo mwina anasankha "Sulpiride" kapena "Prosulpin". Pali analogue wina wa mankhwala - "tiaprid", iye ankaona kwambiri Kufikika, izo si njira otchuka, ulimi zoweta mankhwala amene amachita ndi kampani "Organic". Monga mbali ya "tiaprid" kudzapereka yemweyo yogwira mankhwala, zomwe ndi mbali ya mankhwala "Tiapridal". Kagwiritsidwe analogs Guide akuonetsa kuti kusankha, pamene woyambirira sangathe ntchito imodzi ndi mankhwala ena amayambitsa zotsatira zina zoyipa ndi sasamalira zotsatira ankafuna. Mankhwala kunali kogwira mtima kwambiri, ganizirani ambiri mfundo imene anasankha.

Pa mankhwala, m'pofunika kutsatira malangizo a dokotala onse ndi malangizo, lomwe lili ndi malangizo ntchito. "Tiapridal", monga momwe ndemanga, nthawi zambiri, ntchito kuthetsa zikhalidwe limodzi ndi chisangalalo mantha ndi makhalidwe aukali, mowa maganizo. Kawirikawiri, odwala ndi madokotala amakhutira ndi zotsatira za mankhwala. Mwachidule, Inde refresher si chofunika chifukwa zotsatira anakhumba kusiyana pambuyo kukhazikitsa njira yoyamba. Reviews kusonyeza kuti odwala mankhwala "Tiapridal" yosavuta kugwiritsa ntchito.