Kuchuluka prothrombin nthawi zoyenera kuchita komanso m'mene kubwerera mwakale. Kodi "prothrombin nthawi"

Nthawi zambiri pamene mayesero zasayansi wapadera anasonyeza kuti wodwalayo chawonjezeka prothrombin nthawi. Kodi umboni motero? Koopsa ndi chikhalidwe ichi? N'chifukwa chiyani tiyenera kudziwa prothrombin nthawi, ndi amene zikusonyeza kusanthulidwe ka deta? Nkhanizi ndi chidwi ambiri.

Kodi prothrombin nthawi?

Ndi palibe chinsinsi kuti magazi ndondomeko clotting n'chofunika kwambiri kuti uziyenda zachilendo m'thupi la munthu. Komanso, mwazi lili ndi zinthu zapadera zimene zingawalepheretse kuchuluka clotting, potero popewa mapangidwe magazi kuundana ndi blockage Mitsempha. Bwino ntchito zigawo ziwiri izi zipangitsa kugwira ntchito za masiku onse machitidwe onse limba.

Kuti timvetse kodi prothrombin nthawi ayenera kuonedwa ndi limagwirira wamba clotting. Kuwonongeka kwa mpanda chotengera amachititsa kutsegula kwa wapadera enzyme zovuta zimene zimapereka mapangidwe chingwe Ulimbo. ulusi awa chimango amphamvu kwa magazi aumirira ku yake kuti. magazi dongosolo clotting akhoza kuthamanga mu njira ziwiri - ngati kuonongeka zigawo kunja kapena mkati mwa chotengeracho.

Choncho, prothrombin nthawi kumathandiza kudziwa mmene kudya dongosolo magazi clotting ndi kutsegula kunja.

nthawi Prothrombin, INR ndi prothrombin index - ndichiyani?

Mwachibadwa, mlingo wa clotting magazi vuto la kuwonongeka zigawo kunja kwa mpanda chotengera si chizindikiro mtheradi. Mwa njira, nthawi zambiri MF ayenera kukhala pakati masekondi 11 mpaka 16, ndi kuti apeze deta yolondola pa ntchito za thupi, mayesero zina.

Mu mankhwala amakono, ntchito Mayiko dekhetsa alionse m'dzikoli pali kapena INR. Pamene kafukufuku ofanana wodwalayo prothrombin nthawi poyerekeza ndi index womwewo wa madzi a m'magazi dekhetsa mfundo lonse. chilinganizo amaoneka ngati izi: PT mtima / PT dekhetsa plasma (chotsatira liukitsidwa msinkhu otchedwa mayiko index thromboplastin tilinazo).

Prothrombin index komanso Mzimuyo chiŵerengero cha PV kulamulira plasma PT mtima plasma, koma monga anthu a. Mwa njira, nthawi zambiri zosonyezera ayenera 95 - 100%.

Prothrombin nthawi Quick lero mayeso molondola kwambiri. kafukufuku amathandiza kuyerekeza ntchito za wodwalayo prothrombin zovuta ndi kulamulira magawo plasma.

Zikuonetsa kuti kafukufuku

Ndipotu, pali matenda ambiri ndi matenda zokhudza ndondomeko ya clotting magazi. Ndicho chifukwa chake phunziro limeneli ikuchitika pafupipafupi zokwanira. Mwachitsanzo, chikuyendetsedwera odwala thrombosis ankaganizira. kusanthula akusonyezanso kuti ngati wodwala anapeza mikwingwirima ambiri ndi haemorrhages chiyambi osadziwika.

Kafukufuku yemweyo ntchito pamodzi ndi njira zina kuti aone ntchito kwa chiwindi. Ngati mukukayikira kuti munthu akusowa kapena kuswa kagayidwe wa vitamini K amathanso kutumiza odwala yoganizira. Prothrombin nthawi anatsimikiza ndi amayi apakati, monga nthawi imeneyi uka kwa ena mavuto.

Kodi kuchita zitsanzo mpanda?

Pofuna kudziwa prothrombin nthawi, muyenera plasma atsopano. Choyamba khalidwe magazi zitsanzo zosankhidwazi ndi mtima. Zodabwitsa ndizakuti, mu nkhani zitsanzo iyi ikuchokera mtsempha, ndi kuziika mu chubu okhala ndi sodium citrate, amene chimamanga kashiamu ayoni.

Ndipotu, kukonzekera mwapadera mayeso si chofunika. Kusala magazi chiphaso, choncho mu Laboratories kwambiri magazi zitsanzo zosankhidwazi imagwiridwa m'mawa (kwa maola 11). Ambiri mwina, udzapeza zotsatira za tsiku lotsatira. Iwo ayenera kukumbukira kuti zinthu zina mukhoza skew zotsatira, chotero patsogolo Akukuyetsani ayenera kukaonana ndi dokotala.

Kodi kudziwa prothrombin nthawi zasayansi?

Tanthauzo la nthawi prothrombin - zimatenga osavuta. Monga tanenera kale, pambuyo zitsanzo zosankhidwazi magazi wothira citrate potaziyamu ndi kuwapititsa ku zasayansi. Kenako, chitsanzo linatekeseka ndi kuika mu centrifuge pa kutentha 37 ° ^C. Kenako, chitsanzo Chinawonjezeka chofunika kuchuluka kwa calcium, ndiyeno minofu chinthu clotting. Ndiye intersect nthawi imene thrombus anapanga. Monga tanenera kale, ayenera masekondi 11-16.

Kuwonjezera ntchito

Ngati kukwezeka prothrombin nthawi - ndi oopsa? Mwatsoka, zotsatira si nthawi zonse zizigwirizana mtengo yachibadwa. Ngati zakusokonenezedwa kwa kuchuluka prothrombin nthawi?

• Pali matenda ena chibadidwe limodzi ndi akusowa zinthu clotting.
• Nthawi zina osakwanira kuchuluka kwa zinthu clotting ndi zinazake. Makamaka ngati dziko iwo zimawonedwa zingapo za matenda autoimmune ndi amyloidosis.
• kusintha woteroyo IP amapezeka matenda a chiwindi ndi chiwindi kulephera.
• chifukwa mwina DIC.
• Polemba hypovitaminosis K komanso kuchuluka prothrombin nthawi. Nawonso akusowa vitamini izi zingaoneke pa dysbacteriosis, malabsorption matenda, komanso matenda a ndulu ndi kapamba.
• Kusintha phwando MF amatsogolera ena anticoagulants.
• Chachikulu magazi akhoza kusokoneza zotsatira za phunzirolo.

Ngati kugunda ndi adatchithisira

Odwala ena prothrombin nthawi yafupika - ndi thrombus (magazi aumirira) mitundu zambiri mofulumira kuposa chofunika. Ndi chikhalidwe oopsa, amene ana amakumana ndi chitukuko cha occlusion mtima.

Nthawi zambiri, kuchepa PV limasonyeza kukhalapo kapena chiopsezo thrombosis, umene uli woopsa kwambiri, monga zambiri kuopseza kuti moyo wa wodwalayo. Kutsitsa amaganizira kutenga magulu ena a kulera m'thupi. Chifukwa angakhalenso polycythemia. Mu amayi apakati, magazi kuundana zambiri mofulumira mu trimester wachitatu wa mimba.

Amene zingakhudzire yolondola kuwunika?

Mwakucimbidza Dziwani kuti pali zinthu zambiri, amene mwa njira ina zingakhudze chifukwa cha kuwunika. Monga tanenera kale, anticoagulation ndi ena mankhwala m'thupi achuluke kutalika kwa thrombus mapangidwe. Koma pali zoletsa zina zina.

Makamaka, zotsatira kufufuza zonama mu choncho, ngati mukutenga aspirin barbiturates, mankhwala okhala ndi mavitamini K. Komanso, nthawi prothrombin, kusintha magulu ena a antibayotiki.

mavuto m'mimba akhoza kusokoneza zotsatira za kuwunika. Makamaka, amakhala m'mimba kapena kusanza pafupipafupi patsogolo kwa madzi m'thupi. Komanso njira zisakuyenda mayamwidwe mavitamini ndi mchere, kuphatikizapo tocopherol (vitamini K) matenda amenewa.

Ngati kudya zakudya zomwe zili yambiri vitamini K, zotsatira chiyeso kukhala zolakwika. Ndipo kutatsala masiku ochepa zofufuza za kuchepetsa kuchuluka kwa nkhumba ndi ng'ombe chiwindi, mankhwala soya, nandolo, tiyi wobiriwira, kabichi, burokoli ndi wobiriwira.

The ndondomeko mmene magazi coagulation bongo ndi mowa, kotero, kachiwiri, kutatsala masiku ochepa kuti mayeso pa mowa ayenera adzasiyidwa.

Zinthu zokhudza ntchito mkombero zingaphatikizepo kulandira mankhwala ofewetsa tuvi ndi ena mankhwala ofooketsa tizilombo.

Ngati muli kumwa mankhwala alionse, sindilephera dokotala. Uzani katswiri za maonekedwe a chakudya chanu ndi mavuto a masiku ano thanzi. Apo ayi, kusanthula si nkhani, ndipo adokotala akhoza mankhwala ndi mankhwala zosafunika kwathunthu.

N'chifukwa chiyani kudziwa prothrombin nthawi, mayi woyembekezera?

Ndi palibe chinsinsi kuti pa thupi kubala mkazi (makamaka magazi ndi endocrine dongosolo) wayamba kusintha kwakukulu. N'chifukwa chake kudziwa prothrombin nthawi mimba ndi zofunika kwambiri.

Amayi ena nthawi imeneyi chinawonjezeka clotting magazi, zikubweretsa thrombosis ndi occlusion Mitsempha kuti kunyamula magazi m'thupi la mwana. Pamene sanalandire chithandizo kuphwanya amenewa kungachititse kuti mwiniwakeyo intravascular coagulation, ndipo ngakhale imfa ya mwana wosabadwayo.

Komano, magazi mwina kwambiri kupatulira pa mimba. Zikatero, pali chiopsezo chachikulu cha ataya magazi, makamaka pobereka. Tanthauzo la nthawi prothrombin umathandiza dokotala yake kudziwa kuphwanya makamaka ndi kupewa mavuto.