"Helpeks antikold": malangizo (mapiritsi). Contraindications ndi zotsatira zake zoyipa za mankhwala

Mwa matenda tizilombo wa SARS ndi akatswiri fuluwenza ankaona ambiri. Pafupifupi onse anakumanapo ndi matenda amenewa. Kenako, ganizirani pathologies mwachidule makamaka, komanso wina wa mankhwala amakono analamula kuti mankhwala "Helpeks Antikold" (mapiritsi).

Kufotokozera ODS ndi chimfine (lalifupi)

Miliri ya pathologies izi amakonda kubwera mu kuzizira. Chifukwa cha zimenezi, pafupifupi 15% ya anthu odwala dziko. Chimfine - ndi tizilombo matenda a chikhalidwe opatsirana. Popanda mankhwala zolondola yake ya kudwala uyu angakhale ndi zotsatira sizingasinthe ngakhale imfa. Fuluwenza amakhudza bronchi lalikulu ndi trachea. matenda yodziwika ndi kawopsedwe kwambiri. Pachimake matenda kupuma amakwiya chifuwa, zilonda zapakhosi, kutentha thupi ndi mutu. zizindikiro zofanana muthandize ndi chimfine. Mmodzi mankhwala wamba ndi ogwira kwa pathologies ankaona anaona wothandizila "Helpeks Antikold" (mapiritsi). Reviews madokotala zikuonetsa mogwira mkulu wa mankhwala chifukwa zotsatira zovuta. Malinga ndi akatswiri, mankhwala msanga zokwanira facilitates zizindikiro pachimake matenda. Pa limagwirira kanthu mwatsatanetsatane anauza Ufumuyo malo "Helpeks Antikold" (mapiritsi) malangizo. Akatswiri alendo amanenanso za chitetezo cha ndalama ndi zogwira mtima kulolerana odwala.

katundu pharmacological

Amatanthauza "Helpeks Antikold" (mapiritsi) Mawu limafotokoza yokonzekera zovuta. Mankhwala ali analgesic ndi zotsatira antipyretic. Palinso wofatsa odana ndi yotupa ndi antiallergic kwenikweni. Mogwirizana ndi Ufumuyo ndalama "Helpeks Antikold" malangizo mankhwala kuthandiza kuthetsa mutu, maso madzi, amphuno kuchulukana, chifuwa. Mankhwalawa medicament bwino boma ambiri a chamoyo.

pharmacodynamics

lokonzekera zikuphatikizapo zigawo zikuluzikulu yogwira monga phenylephrine hydrochloride ndi cetirizine, ndi paracetamol. Last ali antipyretic, analgesic ndi wofatsa odana ndi yotupa kwenikweni. Paracetamol amatha kulimbikitsa pakati thermoregulatory mu ubongo imene imalamulira kutentha kwa, ziletsa (ziletsa) kaphatikizidwe wa owayimira yotupa (serotonin, kinin) ndi prostaglandins. Pamodzi ndi chigawo ichi yogwira timapitiriza mlingo wa ululu tilinazo. hydrochloride Cetirizine imatengedwa mokwanira amphamvu a antihistamine. chigawo ichi ndi antagonist kusankha H1 zolandilira. Chifukwa ntchito gistaminoposredovannoy ake deceleration amapezeka gawo oyambirira sayanjana. Cetirizine hydrochloride amachepetsa Kusamuka kwa eosinophils ndi kufalitsa owayimira yotupa. Chifukwa ichi, nayenso imafoola ndi mochedwa matupi awo sagwirizana anachita. Cetirizine hydrochloride ali pafupifupi ziribe mphamvu pa maselo ena. Pa nkhani imeneyi, zilibe imfayo antiserotoninovym zoipa ndi zotsatira anticholinergic. Gidrohhlorid phenylephrine akuchita monga kusankha alpha-agonists. Chifukwa zotsatira vasoconstrictor wogwidwa ndi mbali yogwira, amachepetsa kutupa kwa amphuno mucosa ndi kuchuluka kwa allocated chinsinsi. Potero kuwongolera kupuma m'mphuno, ntchito Ndime ya mpweya.

Pharmacokinetics

Paracetamol mwachilungamo mofulumira odzipereka kwa dongosolo m'mimba. Ndende pazipita anati plasma pambuyo mphindi 10-60. chigawo The mofulumira anagawira mu zimakhala za thupi. Pamene ntchito Mlingo mwachizolowezi achire, zochepa yaing'ono (za 28-50%) a paracetamol amagwirizana ndi mapuloteni. Hafu ya moyo - maola 1-3. analgesic zotsatira nthawi - za 4-6, ndi antipyretic - za 6-8 maola. Kagayidwe ambiri maselo a chiwindi. Paracetamol adzamasulidwa dongosolo makamaka aimpso mu mawonekedwe a conjugates sulphate ndi glucuronic ndi inu. Pasanathe 5% ndi excreted sichinasinthe. Cetirizine hydrochloride komanso mofulumira odzipereka kwa dongosolo m'mimba. Chakudya wambiri sizichepetsa mphamvu ya mawu, koma pang'ono kumachepetsa mlingo wa mayamwidwe. Ndende pazipita chigawo chimodzi mu plasma anati pambuyo theka la ola ntchito 10 mg. Excretion wa cetirizine ikuchitika makamaka mu mkodzo mu mawonekedwe unmodified. Odwala ndi ntchito zolimbitsa kapena wofatsa mkhutu aimpso hafu ya moyo kuchuluka kwa maola 19-21. Pafupifupi 90% ya chigawo chimamanga zonsezo plasma. Phenylephrine hydrochloride mofulumira odzipereka, koma chifukwa cha kwambiri presystemic kagayidwe (makamaka etorotsitah), bioavailability ake zokhudza zonse ndi 40%. Atalandira mlingo akangofika ndende pazipita anati SPUS ola limodzi kapena awiri. Madzi a m'magazi theka moyo mu uthunthu wa maola 2-3. Pambuyo mayamwidwe amapezeka kwambiri biotransfomatsiya phenylephrine ndi chiwindi. Excretion kumachitika makamaka kudzera impso mu mawonekedwe a mankhwala kuwonongeka. Zosakwana 20% adzamasulidwa mu mawonekedwe unaltered.

Zikuonetsa "Helpeks Antikold" (mapiritsi)

Kuchokera pa zimene zimathandiza mankhwalawa? Kumatanthauza ikhale mankhwala symptomatic wa fuluwenza ndi matenda pachimake kupuma tizilombo zovuta ndi matenda hyperthermia. kuwerenga chikukwaniritsa ndi Ufumuyo kwa medicament "Helpeks Antikold" (mapiritsi) malangizo. Akatswiri alendo amati mankhwala ayenera kuyamba pa chizindikiro choyamba cha kudwala. Mankhwalawa m'mbuyomo anayamba, kosavuta kudzatenga lipole.

mlingo

Phwando ayenera kuchitika monga analimbikitsa m'gulu ndi mankhwala "Helpeks Antikold" malangizo. Mapiritsi amapatsidwa Odwala zaka 12 zakubadwa. Mlingo - 1 pc. 4 p. / Tsiku. odwala ambiri amafunsa kuti: "Ine ndi magome olembedwa" Helpeks Antikold "yaitali bwanji kuti achitenge icho.?" Kutalika kwa mankhwala si masiku oposa 5. Pakati Mlingo koyenera kukhala ndi imeneyi ya ola 4. Amatanthauza kumwa ola mutadya. Azichapa pansi ndi madzi lalikulu zedi. Zina ndi mankhwala "Helpeks Antikold" (mapiritsi) akuonetsa mlingo malangizo amaikidwa dokotala. Ngati palibe zotsatira sayenera upambana izo. Pankhaniyi, muyenera kuona katswiri. Ngati ndi kotheka, adokotala akhoza mankhwala mankhwala osiyana m'malo amatanthauza "Helpeks Antikold" (mapiritsi). Analogs wothandizila (mankhwala "Antigrippin", "Aksagripp", "Antiflu", "Coldrex", etc.) ayenera kusankhidwa yekha katswiri.

Amene ali osavomerezeka chida?

Pokonzekera "Helpeks Antikold" (mapiritsi) contraindications ali motere:

• Munthu hypersensitivity kwa zigawo zikuluzikulu.
• Oopsa.
• Hyperthyroidism.
• Mtima kudwala.
• Mkaka wa m'mawere.
• Mimba.
• Age zaka 12.

Awa ndi zopinga zazikulu zimene amapereka njira wotsagana "Helpeks Antikold" malangizo. Miyala komanso osavomerezeka imodzi ndi antidepressant tricyclic kapena MAOI.

mbali zotsatira

Mankhwala akhoza kungasokoneze pa ntchito kwa dongosolo mtima. Makamaka, pangakhale kuchepa kapena kukhala pampanipani, palpitation. Ndi mwina tachycardia. Odwala ena, pali kusokonezeka kwa dongosolo mkodzo. Makamaka, ndi chiphunzitso "Helpeks Antikold" (mapiritsi) (malangizo Buku lili mfundo zimenezi) zingachititse kuphipha wa ritsa mkodzo kapena vesical sphincter. Ophatikizana mankhwala ndi opiates zingachititse posungira wa mkodzo. Mankhwala lili ndi zotsatira sedative, zikhoza kusinza, amaona chikumbumtima, mphwayi, ulesi, mutu. mankhwala akhoza kuona kuwonongeka mu thupi ndi maganizo ntchito, dysphoria, kusawona bwino, kusintha maganizo, nkhawa. zotsatirapo zimenezi akukhudzana matenda a CNS. Malinga ndi akatswiri, iwo uka kwa owonjezera mlingo akangofika medicament. Mankhwala akhoza kuyambitsa ndi kukhumudwa m'mimba dongosolo ntchito. Makamaka mankhwala akhoza kuona kusapeza m'mimba kapena m'matumbo, youma pakamwa, kusanza kapena kunyansidwa. Sayanjana monga totupa pakhungu.

Kusamala

Monga tangotchulawo, ngati mupitirizabe kusonyeza zizindikiro, dokotala. Ayenera kukaona katswiri mu nkhani ya amveke mawonetseredwe kudwala. Kuwonjezera zofooka pamwamba, pali zina zimene muyenera kukhala osamala kwambiri. mndandanda lili Ufumuyo kwa medicament "Helpeks Antikold" malangizo. Mapiritsi, makamaka, ndi amawagwiritsa odwala ndi opuwala aimpso kapena ntchito kwa chiwindi. Pa mankhwala, mlingo siziyenela. Komanso, musatenge mankhwala ena, monga gawo limene pali paracetamol. Mwina cha mankhwala osokoneza bongo ndi apamwamba kwambiri odwala matenda chiwindi netsirroznymi, chikwiyire mwa uchidakwa. Tiyenera kusamala poika mankhwala odwala matenda a shuga, komanso mbali-kutsekedwa khungu. Tiyenera kukumbukira kuti felilefrin angathe kuonjezera zoipazi. Pa nkhani imeneyi, mungafunike kusintha mlingo odwala kulandira chithandizo antihypertensive, komanso zolandilira beta-adrenergic. Monga mbali ya mankhwala "Helpeks Antikold" (mapiritsi) (chithunzi cha mankhwala limeneli m'nkhani) lili aspartame. Izi chigawo chimodzi - gwero la phenylalanine. pawiri Izi zikhoza kusokoneza chikhalidwe cha odwala phenylketonuria. Iwo ayenera kusankha mankhwala odwala ndi osowa cholowa fructose tsankho, sucrase-isomaltase akusowa, komanso malabsorption shuga-galactose.

Mimba ndi mkaka wa m'mawere

Zotsatira chokwanira kafukufuku kunenanso chitetezo cha ntchito ndalama "Helpeks Antikold" pa nthawi awa. Anapeza kuti phenylephrine ndi paracetamol akhoza kulowa mu mkaka. Pa nkhani imeneyi, mankhwala "Helpeks Antikold" pa mkaka wa m'mawere sikuloledwa. Ngati ndi kotheka, mankhwala mu kudya imeneyi ayenera anasiya.

Kuti mudziwe zambiri,

Mankhwala zingachititse kusinza, kusawona bwino ndi matenda ena CNS. Pa nkhani imeneyi, pakuti nthawi ya mankhwala, odwala sayenera zinthu zingakhale woopsawo. Makamaka izo nkhawa madalaivala ndi amene ntchito zokhudzana zimagwirira ndipo amafuna mkulu ndende chidwi ndi quickness mosiyanasiyana psychomotor. Efficacy ndi chitetezo odwala pansi zaka 12 sichinayambe anakhazikitsa. Mogwirizana ndi mankhwala "Helpeks Antikold" odwala mu gulu m'badwo uwu si anapatsidwa.

mogwirizana

Amatanthauza "Helpeks Antikold" sayenera kuperekedwa molumikizana ndi Mao zoletsa ndi kutambasula masabata 2- pambuyo phwando awo. Osavomerezeka mankhwala imodzi ndi mankhwala ena okhala panado, ndipo anafuna kuti mankhwala a maganizo, matenda Parkinson, matenda a m'maganizo. Yaitali ntchito wothandizila "Helpeks Antikold" umathandiza zotsatira za mankhwala "Warfarin" ndi coumarins ena. zotsatira chidwi chinaoneka ndi mankhwala likukulira. Pamodzi ndi kuvomereza amatanthauza "Helpeks antikold" ndi medicament "Cholestyramine" absorbability amachepetsa ndi imafoola zimene paracetamol. Zomwe mayamwidwe mankhwala chigawo monga "Domperidone" ndi "metoclopramide". Mu ntchito molumikizana ndi NSAIDs kumachititsa cha kuwonongeka aimpso. Chiopsezo zotsatira poizoni kumatheka ndi chithandizo concomitant ndi mankhwala kuti kuonjezera ntchito michere chiwindi. Izi makamaka monga barbiturates, mankhwala antiepileptic ndi mankhwala "Rimfampitsin". Medicine "salicylamide" kumawonjezera theka moyo wa paracetamol. Zotsatira Hepatotoxic wa yotsirizira akhoza kukula chifukwa cha ntchito ophatikizana a mankhwala "Helpeks Antikold" ndi Mowa.

ambiri osokoneza

Pamene anatengedwa mu kuchuluka Zoposa ndi achire komanso anapereka pamaso pa mfundo zoopsa ali paracetamol hepatotoxic kwenikweni. Pambuyo mankhwala ambiri osokoneza ndi matenda choipa chiwindi anati pambuyo maola 12-48. Mwa zizindikiro woyamba titchedwe blanching wa khungu, kupweteka pamimba, kusanza ndi nseru, matenda a anorexia. A chiopsezo nthenda ndondomeko shuga kagayidwe ndipo mwina acidosis. Milandu kapamba ndi arrhythmias chifukwa kuchita. Zikuoneka ngati necrosis a chiwindi ndi impso glomeruli. Pankhaniyi cha mankhwala osokoneza bongo angathe thrombocytopenia, analowa hypoglycemic chikomokere. Kuchuluka tulo pamene kulandira wambirimbiri medicament chifukwa zochita za cetirizine. Pa nthawi yomweyo ana malemeredwe koyamba kumachitika, kenako amapereka njira mphwayi. Mu ambiri osokoneza ngakhale boma yachibadwa thanzi amatchula katswiri wa posachedwapa.