"Disulfiram": ndemanga. "Disulfiram": kufotokoza, mtengo

M'nkhani ino tinaganiza kuti ndikuuzeni inu kuti ndi mankhwala monga "Disulfiram". Malangizo ntchito, maganizo ndi mmene ndalama lidzayeretsedwa pansipa. Komanso, muphunzira kuti kodi mtengo wa mankhwala anati, chifukwa amapangidwa m'njira ina iliyonse imene m'gulu kapangidwe kake, ndi zina zotero D..

Mawonekedwe ndi zikuchokera ma CD

The medicament "Disulfiram", malangizo ntchito imene akachita m'bokosi chidapangidwa kuchokera ku katoni, ndi akugulitsa mawonekedwe a njira wochuluka ndi miyala chifukwa makonzedwe m'kamwa ndi implantation.

Mawonekedwe woyamba kamapangikira vayozi wa 20 ml, ndipo lachiwiri ndi lachitatu - mu mitsuko galasi pa mayunitsi 10 ndi 20 motero.

The yogwira pophika medicament ndi disulfiram. Kuwonjezera izo, mankhwala lili komanso zigawo zina (malingana ndi mitundu kumasulidwa): kolorayidi sodium, mannitol, wowuma, sodium stearate, msomali-6000, MCC, calcium diphosphate, hydroxypropyl mapadi, asidi stearic ndi polyoxyl 40.

katundu pharmacological

Kodi patsogolo pathu mankhwala? Chimene iwo anena za iye ndemanga mankhwala? "Disulfiram" ali ndi zotsatira kutchulidwa odana ndi mowa.

Mukalandira chida ichi amatchuka chifukwa zotsatira zake chidwi kagayidwe mowa. Chifukwa, metabolites otetezeka anapanga, omwe amaonjezera ndende ya poizoni monga acetaldehyde. Ndipo Iye ndiyo efficacy wa mankhwala.

Ndi utsogoleli mtsempha wa medicament ndi, komanso odwala ake m'kamwa pafupifupi nthawi yomweyo anayamba kumverera amatuluka otentha, pachimake dyspepsia, tachycardia, asthenia amphamvu ndipo ngakhale pangozi hypotension. Komanso, maonekedwe a kuledzera ndi acetaldehyde kumathandiza tikamapita ku mowa ndi kuwonongedwa kwa cholinga mtima mowa.

magawo pharmacokinetic

Kodi kuganizira ali mankhwala magawo kayendedwe? Nanga bwanji ndemanga zake lipoti mayamwidwe? "Disulfiram" ndithu mofulumira ndipo pafupifupi atamezedwa kotheratu kwa m'matumbo.

Pamene ntchito, pali mkulu kagayidwe wa chigawo yogwira, imene metabolites angapo anapanga. Derivation wa mankhwala ikuchitika mwa mapapo ndi impso.

zikuonetsa

Mankhwala "Disulfiram", mtengo wa chomwe chili m'munsimu, akusonyeza kuti:

• chithandizo cha uchidakwa aakulu;
• kupewa muyambirenso mankhwalawa uchidakwa aakulu.

Tengani mankhwala pa nzeru zake osafunika. Izo ziyenera anaika dokotala.

contraindications

Mankhwala "Disulfiram" m'nsinga ndi pakamwa ali osavomerezeka chifukwa matenda otsatirawa:

• matenda neuropsychiatric;
• khunyu;
• shuga.

Komanso, mankhwala si anasonyeza woyembekezera, ndi kudziwa chigawo chimodzi yogwira ndi chigawo zina, yoyamwitsa.

Tiyenera kuona kuti ndi kusamala kwambiri mankhwala tikulimbikitsidwa kuti kutenga odwala ndi mkhutu chiwindi ntchito, dongosolo kupuma impso.

Mankhwala "Disulfiram": malangizo ntchito

Kugwiritsa ntchito njira iliyonse ndalama ndi chovomerezeka yekha pa malamulo dokotala. dokotala ayenera kuchita kufufuza zonse zimene wodwalayo, kenako sankhani munthu chithandizo chakudya ndi kumwa mankhwala iye.

Malinga ndi malangizo, tsiku mlingo avareji mankhwala kwa makonzedwe m'kamwa ndi za 125-500 mg.

Koma jekeseni ndi implantation mankhwala, ndiye ndondomeko izi ziyenera kuchitidwa ndi wokonza odziwa. Pankhaniyi analimbikitsa mlingo wa mankhwala zimadalira makhalidwe a mtima kwakukulu ndi matenda alipo.

zotsatira zoyipazi

zotsatira zoyipa za mankhwala funso akhoza Ndikaitana? Nanga bwanji izi kuti ndemanga? "Disulfiram" kawirikawiri kukhala chifukwa zochita oopsa mbali. Pamene ingested kungakhale ena kupatuka kapepala kakuti m'mimba ndi kukhalapo kwa kukoma zachitsulo ndi chitukuko cha matenda a chiwindi.

Komanso, kuyan'anila angayambe ntchito mantha dongosolo. Mikhalidwe osafunika monga polyneuritis wa miyendo m'munsi, matenda okhudza ubongo, kuiwala, disorientation ndi mutu.

Komanso, musati kukusalani chitukuko cha zochita osiyanasiyana awo sagwirizana, amene amayamba ndi atamwa mowa (mwachitsanzo, kugwa, zikwapu, arrhythmias mtima oziziritsa edema ndi m'mnyewa wamtima infarction).

Zizindikiro cha mankhwala osokoneza bongo

Kukonzekera "Disulfiram" pa mlingo waukulu angathe kuyambitsa zotsatira monga kugwa, chikomokere ndi zoopsa zochita ubongo.

Kuthetsa zizindikiro zimenezi ayenera kukhala mankhwala symptomatic mu chipatala, amene ayenera zinthu detoxification.

ZINGATHANDIZE medicament

Akatswiri atsimikizira kuti neutralization wathunthu wa mankhwala akhoza kukhala.

Ngati ndi kotheka, linanena bungwe "Disulfiram" kwa thupi (mwachitsanzo, mu zochita kwambiri moti kumene anatengera mlingo wa mowa) ikuchitika kayendetsedwe.

Monga mankhwala ntchito mankhwala ascorbic asidi izi. Iwo kutumikiridwa m'nsinga. mchitidwe uwu salola mowa lidzasanduke acetaldehyde, chimenenso, amachititsa nkhawa.

Ena ntchito ephedrine ndi H1-blockers.

Mwanjira mankhwala

Ndi zovomelezeka ndi kugwiritsa ntchito mankhwala ena patsogolo pathu mankhwala? Nanga bwanji ankachita mankhwala ndemanga kuti? "Disulfiram" osakaniza anticoagulants kumawonjezera zochita zawo, komanso kumaonjezera ngozi ya magazi.

Munthawi yomweyo chithandizo ndi mankhwala mankhwala amene zimapukusidwa mu chiwindi, akhoza kwambiri amanyoza pa ndondomekoyi.

Yonseyi Mao zoletsa, antidepressants tricyclic ndi ena ofanana phenothiazine ndi "Disulfiram" angapereke kwa zikamera cha zochita zovuta mbali.

Kuphatikiza izi zikutanthauza ndi "buspirone" chimachititsa chitukuko cha zinyengo. mankhwala monga "Amitriptyline", nthawi zambiri timapitiriza zotsatira za "Disulfiram" ndi kukwezedwa zotsatira zake poizoni pa wamanjenje dongosolo.

Ankaona medicament angathe kuwonjezera ndende ya chlordiazepoxide ndi ntchito diazepam mu magazi, kuchepetsa mphamvu ya zochita poizoni ndi kuchititsa chizungulire.

Ndi kuphatikiza "Disulfiram" ndi "isoniazid wa" angathe maganizo ndi chizungulire, "a metronidazole" - chisokonezo ndi pachimake psychosis, ndi "Omeprazole" - chakhungu manyazi, ndi tiyi kapena khofi - yafupika excretion ake thupilo.

"Chlorzoxazone" kumaonjezera ndende ya mankhwala odana ndi mowa magazi, ndi "Chlorpromazine" amakulitsa hypotension.

Mankhwala "Disulfiram": ndemanga, mtengo ndi analogues

amagawanika ndi mankhwala monga "Ekzorran", "Radotera", "Aspen", "Krotenal", "Tetlong", "Refuzal", "Stoptil", "Antietil", "Kontrapot", "Tetradin", "Antietan" "Dizetil", "Alkofobin", "Aversan", "Anticoli", "Antabuse", "Esperal", "Lidevin", "Abstinil".

Kodi zambiri ndi mankhwala "Disulfiram"? Mtengo wa mankhwala a mapiritsi Mitandadza 200-1000 rubles (malingana ndi Mlengi). Pankhani mawonekedwe a m'mimba, komanso njira wochuluka, iwo zikhoza kugulidwa kwa 600-2400 rubles.

ndemanga kwambiri za chiphunzitso pano abwino. N'zochititsa chidwi kuti mankhwala amene amagwiritsidwa ntchito mankhwala chinsinsi cha anthu ndi uchidakwa. Akatswiri musati amalangiza kupereka malo opanda nzeru wodwalayo.

Malinga ndi maganizo a anthu amene anali mankhwala ankaona mogwira mtima kwambiri amalimbana ndi chilakolako chofuna kutenga muyezo atsopano mowa. Childs, pambuyo pa kulandira mankhwala wodwala ukapezeka tikamapita ku mowa. Ngati mowa chinaperekedwa akachoka mankhwala, izo zimayambitsa pachimake dyspepsia, ankatenthetsa, asthenia kwambiri, tachycardia, ndipo ngakhale pangozi hypotension.