"Poliglyukin": malangizo ntchito, contraindications, ndemanga

"Poliglyukin" - antishock plazmozameshchath medicament facilitates chimathandiza wa Bcc. Motero, ntchito ya mankhwala ndi zizipita ku guluu wolimba wa maselo othandiza magazi kuundana ndi maselo ofiira.

Zikuchokera chikukhudza 'polyglukin "

Chifukwa cha mankhwala - dextran. Mu botolo galasi munali 200 ndi 400 ml ya yokonza mu mawonekedwe a njira amadzimadzi. The zikuchokera mankhwala lili sodium kolorayidi ndi madzi a jekeseni.

pharmacodynamics

"Poliglyukin" malangizo kusonyezedwa monga mankhwala ndi antiagregatnym ndi zotsatira hemodynamic. The mankhwala ndi hydrophilic polysaccharide kumanga madzi. Pambuyo ntchito mankhwala Bcc anabwezeretsedwa mu nthawi yochepa chifukwa chakuti kuti zimatenga madzi okwanira.

Mbali yogwira ali ndi mkulu maselo kulemera, kotero mu m'magazi ndi pa nthawi yaitali, ndipo pa kayendetsedwe pang'onopang'ono umadutsa makoma chotengera. Features mankhwala mwamsanga Kuonjezera ndi yaitali kusunga magazi yachibadwa. "Poliglyukin" kumachepetsa minofu edema, limabwezeretsa Bcc kumatha kuphipha, lomwe limapezeka mu zotengera zotumphukira.

Kuyimitsidwa bata ndi bwino magazi mankhwala "Poliglyukin" malangizo limasonyeza kuti mankhwala zimapangitsa magazi zochepa viscous. Anthu, kanjedza dekhetsa, wosweka chifukwa chitukuko cha mantha: microcirculation, nthenda yotaya magazi kwa zimakhala ndi.

Pharmacokinetics

Excretion wa medicament opangidwa m'thupi makamaka ndi impsozo. Tsankho kuchotsa ikuchitika masana. "Poliglyukin" kuchotsedwa bwinobwino, gawo zonyozeka zace akulowa maselo a dongosolo reticuloendothelial ndipo waikamo kumeneko pang'onopang'ono amapezeka akuwaza medicament. Chifukwa ndondomeko imeneyi, shuga amapangidwa, omwe si monga gwero la mphamvu. Little "polyglukin" limalowera mu kapepala kakuti m'mimba.

umboni

"Poliglyukin" malangizo ntchito limakupatsani perekani pamene wosweka capillary magazi. Mankhwala oyenera zochizira limati kakasi ndi Kuteteza (septic mantha, poizoni, zilonda zamoto, ntchito, zoopsa). A mankhwala ntchito mu imfa pachimake magazi zimene zinachitika pa ndi ectopic pregnancy, pobereka kapena chifukwa cha zoopsa mwamsanga kubwezeretsa Bcc. Anakonza ndi hypovolemia, yomwe ndi chotsatira cha plasma kutayikira (chipinda syndrome, amayaka). Mphamvu ya mankhwala zimawonedwa mu kukhazikitsa njira zodzitetezera umalimbana popewa embolism (preoperative, postoperative).

contraindications

Pamaso chithandizo m'pofunika kulabadira contraindications, lomwe lili ndi alumikiza kuti pamalowo "Poliglyukin" malangizo Buku. Contraindications mankhwala ndi kapewedwe kukonzekera izi motere:

• sitiroko oziziritsa;
• Mkulu ICP;
• limati imene oyamba zakumwa lalikulu zedi ndi osafunika;
• matenda limodzi ndi matenda aimpso (anuria, oliguria);
• aakulu oopsa;
• mtima kulephera;
• matenda a homeostasis, coagulation;
• kupitiriza magazi mkati (kupatulapo - magazi pansipa 60 mamilimita Hg ..).

Mlingo chithandizo

A njira yothetsera makonzedwe mtsempha. Pa nthawi imene imfa magazi ndi pachimake, chakuti ntchito kwapakati pa-wolumikizira mankhwala. Mlingo wa utsogoleli mankhwala anatsimikiza payekha ndipo zimadalira chikhalidwe onse wodwala, kugunda kwa mtima wake, kuthamanga kwa magazi ndi hematocrit.

Mwa limati mantha "Poliglyukin" malangizo Buku amalimbikitsa kutumikiridwa bolus mtsempha njira. Chofunika mlingo umodzi wa wothandizila mu Zikatero si zosakwana 400 koma osapitirira 1200 ml. Nthawi zina m'pofunika kuwonjezera mlingo wa mankhwala mpaka 2000 ml. Ngati ntchito ya BP chifukwa cha utsogoleli wa mankhwala kutha mwakale, kusintha kwa oyamba m'malovu mankhwala.

Imfa kwambiri magazi, lolingana 500 ml ndi zambiri, komanso pamaso pa anemizatsii aakulu kupatula ntchito "polyglukin" njira imagwiridwa magazi. Ngati muyeso njira kuteteza mantha pa opaleshoni mankhwala kutumikiridwa kuti adzagwa pamene zoipazi wagwa - ndege. Kuchepa lakuthwa magazi 60 mamilimita Hg. Art. ndi pansi liyenela kukhazikitsa "polyglukin" mu buku la saposa 400 ml intraarterially. Atam'chiritsa ntchito kugwiritsa ntchito mankhwala zokolola kupewa, kulola kupewa chitukuko cha mantha.

njira ndi amagwiritsidwa ntchito pa ndende ya 6% mankhwala yogwira, koma likukhudza "Poliglyukin 33" zina. Malangizo ntchito chimasonyeza kuti chiphunzitso ndi ndende ya dextran ndi reagent wothandiza pamene poona ngakhale a olandila ndi mwiniwake.

Pamene m'pofunika kuthetsa lamoto mantha, tsiku loyamba wamkulu ndi kutumikiridwa kwa 2 zikwi. Chikwi kwa 3. ml njira, umagwiritsidwa ntchito pa tsiku lachiwiri la osapitirira 1.5 zikwi ml kukonzekera.. Nthawi anthu pamene mantha n'kofunika kuchotsa mwana, izo poyamba kutumikiridwa 40-50 ml ya / kg njira, pa tsiku lachiwiri mlingo pa kilogalamu thupi yafupika 30 ml. Ngati muyeso njira, kuthetsa kuthekera mantha, ana atchule kukapanda kuleka mtsempha njira. Mlingo anafuna mwana ranges ku ml ya 10 mpaka 15 / kg "Poliglyukin" kukonzekera. Malangizo ntchito nyama, nayenso, limachititsa ntchito mankhwala, zochokera oyamba "polyglukin". Pakuti zolinga zimenezi njira mlingo wa 15 20 ml ya / kg. Yoyenera mlingo kwambiri mankhwala anatsimikiza ndi dokotala.

zotsatira zoyipazi

Musanagwiritse ntchito mankhwala "malangizo Poliglyukin 'ntchito, mayankho akulimbikitsidwa kubwerezanso zotsatira zotheka mbali. Kawirikawiri mavuto chiyani osadzuka, ndi thupi la odwala amalabadira mankhwala. Nthawi zina zingaoneke mu mawonekedwe a thupi lawo siligwirizana kakasi anaphylactic, kutupa, kuyabwa ndi totupa. Odwala ena a sternum pali kumverera kwa psinjika, pali ululu. Mwina kupezeka malungo, kungachepetse magazi, mathamangitsidwe wa kugunda kwa mtima. Mungakhale mukuvutika ndi kupuma, chizungulire ndi chitukuko pamaso acrocyanosis. Chifukwa ambiri osokoneza ananyamula katundu owonjezera mtima, amaletsa olumpha mlingo amatanthauza "Poliglyukin" malangizo Buku. Mapiritsi ndi mankhwala ena omwe wodwalayo akusinthira, angasokoneze zochita za njira.

ndemanga Analogs

M'MALO medicament mungathe "HyperHAES", "Reoglyumanom" kapena "Hai-wosabala". Njira zothetsera kuti ntchito kwa cholinga chomwecho monga "Poliglyukin" zimaphatikizapo "Sterofundin", "Reopoligljukin", "Stabizol".

Sinthanitsani "Poliglyukin" malangizo ntchito kulola pa nthawi imene wodwala si woyenera malo ichi. Oloŵa m'malo mwa angagwiritsidwe ntchito "gelofusin", "Refortan N», «Sorbilakt". A kuchita chimodzimodzi angatanthauze "Albunormom" ndi "Neorondeksom".

Reviews zikusonyeza kuti ambiri mankhwala amathandiza kuthetsa vutolo. Koma popeza onsewa ndi osiyana, zotsatira za makonzedwe ake angakhale osiyana. Zikudalira alili. Anthu pa chiopsezo osati ntchito "Poliglyukin" paokha, chifukwa chiopsezo cha dongosolo zosayenera ndalama ndi chitukuko mavuto.

Ntchito yake njira "Poliglyukin" amachita, koma mankhwala, komanso kukhazikitsa kupewa, izo sizinali bwino ndipo kwabweretsa mavuto ena, mlingo wa mankhwala ayenera kusankhidwa ndi dokotala payekha. Only katswiri angathe kupereka mankhwala monga munthu wabwinobwino sangathe molondola kudziwa mlingo chofunika ndi njira yoyenera utsogoleli wa mankhwala. Kugwiritsa Mlingo wa mankhwala ndi owopsa kwa mtima, kotero musatenge ngozi, ndiponso kudzimvera medicate.