'Milgamma' - malangizo ntchito.

mawonekedwe mlingo

Kukonzekera "Milgamma" anamasulidwa mu njira kwa makonzedwe mu mnofu. Yankho wofiira, mandala, mumtundu wa njira limasonyeza kuti mankhwala si "Milgamma". Malangizo ntchito ali ndi mfundo zonse za mankhwala.

The zikuchokera mankhwala ali m'gulu (chiwerengero cha mankhwala anasonyeza pa 1 ml ya mankhwala)

• Thiamine (vit B1) - 50 mg
• Hydrochloride, cyanocobalamin (vit B12) - 500 mcg
• Pyridoxine hydrochloride (vit B6) - 50 mg
• Lidocaine wa hydrochloride - 10 mg

Madzi otchezedwa, sodium hydroxide: Komanso, adjuvants otsatirawa akhoza kugwiritsidwa ntchito benzyl mowa, hexacyanoferrate potaziyamu, sodium polyphosphate.

The kanthu pharmacological mankhwala "Milgamma"

Malangizo ntchito muyezo mankhwala Imafotokoza mwatsatanetsatane za zochita pharmacological. "Milgamma" tichipeza gulu vitamini B ovuta, amene ali ndi ubwino pa matenda osachiritsika ndi yotupa ya mitsempha. Komanso, vitamini imeneyi kupatsa zovuta kuchuluka magazi ndi bwino kugwira ntchito kwa wamanjenje dongosolo lonse.

Thiamine chimachititsa kwambiri mu kagayidwe chakudya ndi mkombero citric acid, ndi kuwonjezera nawo mu kaphatikizidwe triphosphate adenosine ndi thiamine pyrophosphate.

Pyridoxine ndi kulowerera kaphatikizidwe mapuloteni, komanso mu kagayidwe kunyama ndi chakudya.

Imodzi mwa ntchito thupi la mavitamini awa ndi kupititsa patsogolo zochita wina ndi mzake, amene kumaonekera zotsatira pa machitidwe mtima ndi neuromuscular. Pamene boma pyridoxine akusowa angathe avitaminoznoe cropped pambuyo ka zovuta lapansi.

Cyanocobalamin kumapangitsa gemopoez nawo kulenga ya myelin m'chimake, amachepetsa ululu, imakhudzana ndi zotupa wa mantha dongosolo zotumphukira, ndipo akhoza yotithandiza kuwombola mkati mwa kutsegula folate.

Pharmacokinetics

Pharmacokinetics "Milgamma" malangizo ntchito kumaphatikizapo chidule. Thiamine mwachilungamo mofulumira odzipereka pambuyo jekeseni mu mnofu ndi yomweyo akulowa magazi - pambuyo Mphindi 15 kuika maganizo ake mu magazi 484 ng / ml ya mankhwala ngati anali kutumikiridwa 1 ml pa tsiku loyamba la dongosololi.

Pyridoxine pambuyo jekeseni mu mnofu imatsala m'malo mwamsanga kufalitsa zokhudza zonse, pamene atenge mbali ya coenzyme, chifukwa mu phosphorylation wa gulu la methanol mu malo wachisanu.

umboni

"Milgamma" imene ntchito kukuonetsedwa odwala ubongo, zikusonyezedwa matenda otsatirawa ndi syndromes wa mantha dongosolo:

• Nkhope mitsempha paresis
• Ganlionity
• chamawonedwe neuritis
• plexopathy
• polyneuropathy
• neuropathy
• usiku omangana
• radiculopathy
• zosokonezeka ubongo wa osteochondrosis
• Musculo mankhwala syndromes
• sciatica

matenda onsewa ali ndi chidziwitso ntchito mankhwala "Milgamma". Malangizo ntchito, chimene jakisoni ayenera kuyikidwa intramuscularly limapangidwa mlingo analimbikitsa mlingo.

zotsatira zoyipazi

Kugwiritsa ntchito mankhwala zikhoza thupi lawo siligwirizana:

• urticaria
• adakangalika kupuma
• anaphylactic mantha
• itch
• angioedema

Ndi zotsatira zina mbali

• tachycardia
• kuchuluka thukuta
• ziphuphu zakumaso

contraindications

Contraindications ntchito mankhwala imatengedwa kuti:

• ubwana
• Mimba ndi mkaka wa m'mawere
• kulephera mtima
• Hypersensitivity kwa zigawo aliyense lokonzekera

ambiri osokoneza

An ambiri osokoneza mankhwala ali ndi zizindikiro zotsatirazi:

• arrhythmia
• chizungulire
• khunyu

ambiri osokoneza chithandizo ayenera kukhala symptomatic.

Mwanjira mankhwala

Yosemphana ndi njira zimene zili sulfites, chifukwa thiamine waonongeka kwathunthu mu nawo.

Pamaso pa vitamini B mavitamini zovuta zina mwina inactivated.

Levodopa akhoza kuchepetsa zotsatira za pyridoxine.

Kuchepetsa mphamvu ya pyridoxine zikhoza mogwirizana epinephrine, cycloserine, D-penicillamine, sulfonamides ndi norepinephrine.

Thiamine atakwatirana ndi Mercury enaake, oxidizing wothandizira, iodide, nthochi, carbonate, asidi tannic, phenobarbital benzylpenicillin, riboflavin, metabisulfite ndi dextrose.